Mus musculus

0 known processes

March5

membrane-associated ring finger (C3HC4) 5

(Aliases: 1810015H18Rik,Marchv,MGC130121,5730499H23Rik,2310008I22Rik,MGC130122,E130202O05Rik,Rnf153,MARCH-V,2700055A20Rik)

March5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitochondrion organization GO:0007005 134 0.159
Human
macromolecule catabolic process GO:0009057 281 0.147
proteasomal protein catabolic process GO:0010498 98 0.147
cellular macromolecule catabolic process GO:0044265 206 0.132
regulation of mitochondrial fission GO:0090140 3 0.110
Human
negative regulation of cellular protein metabolic process GO:0032269 247 0.108
modification dependent protein catabolic process GO:0019941 133 0.105
endomembrane system organization GO:0010256 147 0.102
cellular protein catabolic process GO:0044257 155 0.084
protein modification by small protein conjugation GO:0032446 187 0.083
Human
cellular response to dna damage stimulus GO:0006974 207 0.078
ubiquitin dependent protein catabolic process GO:0006511 129 0.077
protein ubiquitination GO:0016567 171 0.071
Human
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.062
amine metabolic process GO:0009308 45 0.058
cellular amino acid metabolic process GO:0006520 103 0.057
protein maturation GO:0051604 176 0.055
modification dependent macromolecule catabolic process GO:0043632 133 0.053
protein modification by small protein conjugation or removal GO:0070647 207 0.052
Human
protein catabolic process GO:0030163 221 0.051
intrinsic apoptotic signaling pathway GO:0097193 132 0.048
transmembrane transport GO:0055085 412 0.048
response to oxidative stress GO:0006979 123 0.046
nucleobase containing small molecule metabolic process GO:0055086 352 0.046
nucleoside phosphate metabolic process GO:0006753 338 0.044
cellular amine metabolic process GO:0044106 44 0.042
heterocycle catabolic process GO:0046700 280 0.041
protein processing GO:0016485 163 0.040
endoplasmic reticulum organization GO:0007029 10 0.040
regulation of membrane potential GO:0042391 192 0.040
positive regulation of programmed cell death GO:0043068 218 0.039
membrane organization GO:0061024 245 0.039
response to inorganic substance GO:0010035 96 0.039
nucleoside metabolic process GO:0009116 246 0.039
cytoplasmic transport GO:0016482 234 0.038
aromatic compound catabolic process GO:0019439 286 0.038
sulfur compound metabolic process GO:0006790 100 0.038
mitochondrial transport GO:0006839 36 0.038
dephosphorylation GO:0016311 129 0.037
positive regulation of cell death GO:0010942 224 0.037
apoptotic signaling pathway GO:0097190 306 0.037
positive regulation of hydrolase activity GO:0051345 148 0.036
innate immune response GO:0045087 157 0.035
organic cyclic compound catabolic process GO:1901361 295 0.034
regulation of cellular catabolic process GO:0031329 242 0.034
nucleotide metabolic process GO:0009117 332 0.033
purine ribonucleotide metabolic process GO:0009150 290 0.033
regulation of proteolysis GO:0030162 164 0.032
cellular response to cytokine stimulus GO:0071345 189 0.032
organic acid biosynthetic process GO:0016053 86 0.031
mitochondrion degradation GO:0000422 3 0.030
regulation of apoptotic signaling pathway GO:2001233 197 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
positive regulation of apoptotic process GO:0043065 217 0.029
negative regulation of phosphorus metabolic process GO:0010563 184 0.029
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.029
regulation of cellular amino acid metabolic process GO:0006521 5 0.028
cellular nitrogen compound catabolic process GO:0044270 280 0.028
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.028
ribose phosphate metabolic process GO:0019693 291 0.027
regulation of cellular ketone metabolic process GO:0010565 66 0.027
purine containing compound metabolic process GO:0072521 311 0.027
apoptotic mitochondrial changes GO:0008637 48 0.027
purine ribonucleoside metabolic process GO:0046128 241 0.027
negative regulation of intracellular signal transduction GO:1902532 167 0.027
male gamete generation GO:0048232 285 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.026
sulfur compound biosynthetic process GO:0044272 37 0.026
negative regulation of cellular amine metabolic process GO:0033239 1 0.026
establishment of protein localization to organelle GO:0072594 118 0.026
regulation of hydrolase activity GO:0051336 246 0.026
response to organonitrogen compound GO:0010243 246 0.026
intracellular protein transport GO:0006886 204 0.025
regulation of cytokine production GO:0001817 266 0.025
reactive oxygen species metabolic process GO:0072593 84 0.025
cytokine production GO:0001816 319 0.025
purine nucleoside metabolic process GO:0042278 241 0.024
blood circulation GO:0008015 195 0.024
regulation of protein catabolic process GO:0042176 108 0.023
organelle fission GO:0048285 170 0.023
Human
purine ribonucleoside catabolic process GO:0046130 205 0.023
response to endoplasmic reticulum stress GO:0034976 53 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
negative regulation of molecular function GO:0044092 258 0.022
negative regulation of apoptotic signaling pathway GO:2001234 104 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
regulation of defense response GO:0031347 233 0.022
cellular ketone metabolic process GO:0042180 84 0.022
protein import GO:0017038 101 0.022
nuclear transport GO:0051169 139 0.022
response to radiation GO:0009314 165 0.021
ribonucleoside catabolic process GO:0042454 206 0.021
spermatogenesis GO:0007283 284 0.021
cellular amide metabolic process GO:0043603 58 0.021
positive regulation of proteolysis GO:0045862 85 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.020
positive regulation of defense response GO:0031349 124 0.020
response to reactive oxygen species GO:0000302 56 0.020
cellular response to hormone stimulus GO:0032870 150 0.020
dna metabolic process GO:0006259 303 0.020
protein localization to organelle GO:0033365 185 0.019
Human
locomotory behavior GO:0007626 195 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
regulation of mitochondrion organization GO:0010821 27 0.019
Human
regulation of reactive oxygen species metabolic process GO:2000377 40 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
response to growth factor GO:0070848 198 0.019
regulation of cell activation GO:0050865 289 0.019
regulation of peptidase activity GO:0052547 96 0.019
reactive nitrogen species metabolic process GO:2001057 0 0.019
organophosphate catabolic process GO:0046434 232 0.018
negative regulation of kinase activity GO:0033673 81 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
positive regulation of protein modification process GO:0031401 299 0.018
positive regulation of peptidase activity GO:0010952 49 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
protein targeting GO:0006605 143 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
positive regulation of endopeptidase activity GO:0010950 43 0.017
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.017
positive regulation of cellular catabolic process GO:0031331 148 0.017
inflammatory response GO:0006954 244 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
nucleoside phosphate biosynthetic process GO:1901293 79 0.017
regulation of anatomical structure size GO:0090066 178 0.017
regulation of cellular response to stress GO:0080135 159 0.017
t cell activation GO:0042110 289 0.017
regulation of map kinase activity GO:0043405 120 0.017
rhythmic process GO:0048511 174 0.017
regulation of kinase activity GO:0043549 249 0.017
mapk cascade GO:0000165 281 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.017
ribonucleoside monophosphate metabolic process GO:0009161 80 0.016
circulatory system process GO:0003013 197 0.016
protein oligomerization GO:0051259 67 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.016
carbohydrate homeostasis GO:0033500 128 0.016
myeloid cell differentiation GO:0030099 233 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
negative regulation of protein modification process GO:0031400 163 0.016
immune effector process GO:0002252 321 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.015
leukocyte mediated immunity GO:0002443 174 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
nitrogen compound transport GO:0071705 271 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
cellular modified amino acid metabolic process GO:0006575 63 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
b cell activation GO:0042113 161 0.015
negative regulation of transferase activity GO:0051348 85 0.015
regulation of protein complex assembly GO:0043254 83 0.015
cofactor metabolic process GO:0051186 80 0.015
homeostasis of number of cells GO:0048872 210 0.015
response to lipopolysaccharide GO:0032496 128 0.014
pyridine nucleotide biosynthetic process GO:0019363 4 0.014
regulation of transferase activity GO:0051338 263 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
ras protein signal transduction GO:0007265 77 0.014
nucleoside monophosphate catabolic process GO:0009125 59 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
atp metabolic process GO:0046034 75 0.014
translation GO:0006412 93 0.014
autophagy GO:0006914 45 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
cellular response to amino acid stimulus GO:0071230 29 0.014
regulation of organelle organization GO:0033043 289 0.014
Human
nucleoside triphosphate catabolic process GO:0009143 205 0.014
cellular lipid metabolic process GO:0044255 323 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
regulation of endopeptidase activity GO:0052548 89 0.014
gland development GO:0048732 330 0.014
positive regulation of lymphocyte activation GO:0051251 140 0.013
vascular process in circulatory system GO:0003018 62 0.013
regulation of protein localization GO:0032880 231 0.013
glycoprotein metabolic process GO:0009100 116 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.013
ion transmembrane transport GO:0034220 361 0.013
positive regulation of cell activation GO:0050867 158 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.013
organophosphate biosynthetic process GO:0090407 122 0.012
mitochondrial membrane organization GO:0007006 26 0.012
regulation of innate immune response GO:0045088 91 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
gonad development GO:0008406 141 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
regulation of cysteine type endopeptidase activity GO:2000116 65 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
response to hyperoxia GO:0055093 2 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
glucose homeostasis GO:0042593 128 0.012
regulation of secretion GO:0051046 274 0.012
ossification GO:0001503 216 0.012
oxidation reduction process GO:0055114 342 0.012
regulation of t cell activation GO:0050863 170 0.012
purine nucleoside monophosphate catabolic process GO:0009128 58 0.012
response to oxygen levels GO:0070482 62 0.012
protein localization to mitochondrion GO:0070585 15 0.012
Human
negative regulation of phosphorylation GO:0042326 166 0.012
multicellular organism growth GO:0035264 161 0.012
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.012
cellular response to inorganic substance GO:0071241 37 0.012
spermatid development GO:0007286 108 0.012
positive regulation of innate immune response GO:0045089 80 0.012
defense response to other organism GO:0098542 197 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
lipid biosynthetic process GO:0008610 179 0.011
forebrain development GO:0030900 302 0.011
protein refolding GO:0042026 1 0.011
defense response to bacterium GO:0042742 119 0.011
epithelial cell migration GO:0010631 63 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
myeloid cell homeostasis GO:0002262 114 0.011
neuronal action potential GO:0019228 54 0.011
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.011
response to heat GO:0009408 27 0.011
spermatid differentiation GO:0048515 115 0.011
respiratory system development GO:0060541 190 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
dna repair GO:0006281 107 0.011
lymphocyte proliferation GO:0046651 164 0.011
cellular homeostasis GO:0019725 240 0.011
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.011
negative regulation of cell development GO:0010721 169 0.011
hormone secretion GO:0046879 128 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
compound eye development GO:0048749 1 0.011
interleukin 6 production GO:0032635 58 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
leukocyte proliferation GO:0070661 172 0.011
regulation of cellular response to growth factor stimulus GO:0090287 82 0.011
cation transport GO:0006812 399 0.011
epithelium migration GO:0090132 63 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
regulation of fat cell differentiation GO:0045598 81 0.011
sensory organ morphogenesis GO:0090596 242 0.011
positive regulation of mitochondrion organization GO:0010822 17 0.011
Human
mitotic cell cycle GO:0000278 195 0.010
regulation of lipid metabolic process GO:0019216 118 0.010
cell adhesion GO:0007155 329 0.010
nuclear import GO:0051170 95 0.010
transmission of nerve impulse GO:0019226 76 0.010
regulation of secretion by cell GO:1903530 249 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.010
lateral inhibition GO:0046331 1 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.010
tube closure GO:0060606 91 0.010
response to hydrogen peroxide GO:0042542 32 0.010
asymmetric stem cell division GO:0098722 3 0.010
endocytosis GO:0006897 168 0.010
smad protein complex assembly GO:0007183 1 0.010
t cell differentiation GO:0030217 174 0.010
rna processing GO:0006396 105 0.010
positive regulation of secretion GO:0051047 130 0.010
protein targeting to peroxisome GO:0006625 4 0.010

March5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.041
disease of anatomical entity DOID:7 0 0.041
nervous system disease DOID:863 0 0.041
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.017
musculoskeletal system disease DOID:17 0 0.015
immune system disease DOID:2914 0 0.013
hematopoietic system disease DOID:74 0 0.011