Mus musculus

52 known processes

March7

membrane-associated ring finger (C3HC4) 7

(Aliases: Gtrgeo17,Axot,Axo)

March7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.794
spermatogenesis GO:0007283 284 0.453
cellular macromolecule catabolic process GO:0044265 206 0.434
protein methylation GO:0006479 81 0.416
cellular response to dna damage stimulus GO:0006974 207 0.399
histone lysine demethylation GO:0070076 13 0.269
germ cell development GO:0007281 185 0.262
methylation GO:0032259 134 0.244
regulation of cellular response to stress GO:0080135 159 0.222
chromatin organization GO:0006325 206 0.215
modification dependent protein catabolic process GO:0019941 133 0.206
regulation of organelle organization GO:0033043 289 0.203
positive regulation of protein modification process GO:0031401 299 0.200
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 3 0.186
macromolecule catabolic process GO:0009057 281 0.184
stem cell development GO:0048864 219 0.176
spermatid differentiation GO:0048515 115 0.170
protein modification by small protein conjugation or removal GO:0070647 207 0.169
genitalia development GO:0048806 37 0.165
positive regulation of organelle organization GO:0010638 128 0.164
purine ribonucleotide metabolic process GO:0009150 290 0.161
stem cell differentiation GO:0048863 268 0.153
posttranscriptional regulation of gene expression GO:0010608 155 0.152
myeloid leukocyte differentiation GO:0002573 119 0.143
covalent chromatin modification GO:0016569 163 0.139
male gamete generation GO:0048232 285 0.137
establishment of organelle localization GO:0051656 122 0.127
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.126
regulation of cell migration GO:0030334 219 0.126
negative regulation of cellular protein metabolic process GO:0032269 247 0.121
meiosis i GO:0007127 60 0.117
cation transport GO:0006812 399 0.113
nuclear division GO:0000280 158 0.108
microtubule cytoskeleton organization GO:0000226 157 0.103
translation GO:0006412 93 0.103
i kappab kinase nf kappab signaling GO:0007249 85 0.097
negative regulation of protein metabolic process GO:0051248 282 0.097
pole plasm assembly GO:0007315 2 0.094
inter male aggressive behavior GO:0002121 3 0.094
protein ubiquitination GO:0016567 171 0.093
organelle localization GO:0051640 179 0.091
histone modification GO:0016570 159 0.089
meiotic cell cycle process GO:1903046 77 0.087
positive regulation of cytokine production GO:0001819 174 0.084
protein alkylation GO:0008213 81 0.083
protein catabolic process GO:0030163 221 0.083
erythrocyte differentiation GO:0030218 88 0.082
small gtpase mediated signal transduction GO:0007264 97 0.080
cellular protein catabolic process GO:0044257 155 0.078
chromatin modification GO:0016568 187 0.078
protein modification by small protein conjugation GO:0032446 187 0.078
antigen receptor mediated signaling pathway GO:0050851 64 0.077
mrna metabolic process GO:0016071 84 0.076
nucleoside phosphate metabolic process GO:0006753 338 0.073
cardiac muscle hypertrophy GO:0003300 23 0.073
establishment or maintenance of cell polarity GO:0007163 86 0.070
synaptic vesicle localization GO:0097479 59 0.070
digestive tract development GO:0048565 190 0.070
homeostasis of number of cells GO:0048872 210 0.069
spermatid development GO:0007286 108 0.069
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.067
t cell activation GO:0042110 289 0.067
macromolecule methylation GO:0043414 120 0.067
meiotic nuclear division GO:0007126 115 0.066
regulation of protein catabolic process GO:0042176 108 0.066
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.065
amine metabolic process GO:0009308 45 0.064
regulation of cellular amino acid metabolic process GO:0006521 5 0.064
digestive system development GO:0055123 200 0.062
positive regulation of cell proliferation involved in heart valve morphogenesis GO:0003251 1 0.062
regulation of chromatin modification GO:1903308 57 0.062
ion transmembrane transport GO:0034220 361 0.060
regulation of transforming growth factor beta2 production GO:0032909 2 0.059
positive regulation of protein phosphorylation GO:0001934 242 0.059
regulation of cellular ketone metabolic process GO:0010565 66 0.057
nucleoside phosphate catabolic process GO:1901292 222 0.056
immune response activating signal transduction GO:0002757 116 0.055
organelle fission GO:0048285 170 0.055
leukocyte differentiation GO:0002521 342 0.054
cell cycle checkpoint GO:0000075 47 0.054
regulation of cell motility GO:2000145 236 0.053
rna splicing GO:0008380 54 0.053
positive regulation of cellular catabolic process GO:0031331 148 0.052
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.052
gonad development GO:0008406 141 0.051
modification dependent macromolecule catabolic process GO:0043632 133 0.050
regulation of cellular protein catabolic process GO:1903362 61 0.050
canonical wnt signaling pathway GO:0060070 130 0.049
mrna splicing via spliceosome GO:0000398 43 0.049
purine containing compound metabolic process GO:0072521 311 0.049
regulation of mrna processing GO:0050684 41 0.048
neurotransmitter secretion GO:0007269 62 0.048
ubiquitin dependent protein catabolic process GO:0006511 129 0.047
rna splicing via transesterification reactions GO:0000375 43 0.047
hematopoietic progenitor cell differentiation GO:0002244 143 0.047
digestive tract morphogenesis GO:0048546 147 0.046
regulation of cytoskeleton organization GO:0051493 122 0.046
negative regulation of mapk cascade GO:0043409 65 0.046
regulation of mapk cascade GO:0043408 248 0.045
neuroepithelial cell differentiation GO:0060563 37 0.045
endocytosis GO:0006897 168 0.045
aromatic compound catabolic process GO:0019439 286 0.045
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.045
mrna processing GO:0006397 63 0.044
oocyte construction GO:0007308 2 0.044
regulation of t cell activation GO:0050863 170 0.044
mitotic cell cycle GO:0000278 195 0.044
regulation of cell cycle GO:0051726 281 0.044
mesenchyme development GO:0060485 152 0.043
axon target recognition GO:0007412 4 0.043
regulation of system process GO:0044057 200 0.043
response to radiation GO:0009314 165 0.042
activation of immune response GO:0002253 138 0.040
rna processing GO:0006396 105 0.040
negative regulation of protein maturation GO:1903318 79 0.040
activation of innate immune response GO:0002218 56 0.039
rab protein signal transduction GO:0032482 1 0.039
development of primary sexual characteristics GO:0045137 143 0.039
developmental maturation GO:0021700 193 0.039
dna recombination GO:0006310 92 0.039
regulation of erk1 and erk2 cascade GO:0070372 71 0.038
dna integrity checkpoint GO:0031570 28 0.038
purine ribonucleotide catabolic process GO:0009154 208 0.037
regulation of ras protein signal transduction GO:0046578 114 0.036
dna repair GO:0006281 107 0.036
hepaticobiliary system development GO:0061008 67 0.036
microtubule based process GO:0007017 236 0.036
positive regulation of kinase activity GO:0033674 155 0.036
gene silencing GO:0016458 38 0.035
pigmentation GO:0043473 71 0.035
ras protein signal transduction GO:0007265 77 0.035
regulation of cellular catabolic process GO:0031329 242 0.034
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.034
regulation of protein stability GO:0031647 52 0.032
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.032
mitotic nuclear division GO:0007067 48 0.032
neurotransmitter transport GO:0006836 76 0.032
purine nucleoside triphosphate catabolic process GO:0009146 203 0.032
exocytosis GO:0006887 121 0.032
positive regulation of cell death GO:0010942 224 0.032
positive regulation of mapk cascade GO:0043410 170 0.032
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.032
lymphocyte proliferation GO:0046651 164 0.031
stem cell fate specification GO:0048866 3 0.031
chromatin silencing GO:0006342 15 0.031
oogenesis GO:0048477 56 0.031
positive regulation of proteolysis GO:0045862 85 0.030
negative regulation of intracellular signal transduction GO:1902532 167 0.030
regulation of cellular amine metabolic process GO:0033238 20 0.030
myeloid cell homeostasis GO:0002262 114 0.030
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.030
stem cell maintenance GO:0019827 130 0.030
regulation of protein complex assembly GO:0043254 83 0.030
ribonucleotide catabolic process GO:0009261 208 0.029
respiratory tube development GO:0030323 167 0.029
regulation of protein maturation GO:1903317 96 0.029
regulation of blood circulation GO:1903522 93 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
natural killer cell activation GO:0030101 44 0.029
body morphogenesis GO:0010171 45 0.029
purine nucleotide catabolic process GO:0006195 211 0.028
negative regulation of protein catabolic process GO:0042177 36 0.028
nucleoside catabolic process GO:0009164 206 0.028
heterocycle catabolic process GO:0046700 280 0.028
myeloid cell differentiation GO:0030099 233 0.028
cellular response to lipid GO:0071396 145 0.028
muscle hypertrophy GO:0014896 24 0.028
skeletal system development GO:0001501 356 0.028
regulation of histone modification GO:0031056 56 0.028
mammary gland epithelium development GO:0061180 65 0.028
ossification GO:0001503 216 0.028
purine containing compound catabolic process GO:0072523 213 0.027
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.027
cellular response to organic cyclic compound GO:0071407 87 0.027
nucleotide catabolic process GO:0009166 217 0.026
regulation of response to dna damage stimulus GO:2001020 34 0.026
establishment of vesicle localization GO:0051650 81 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.026
ribonucleoside triphosphate catabolic process GO:0009203 199 0.026
dna damage checkpoint GO:0000077 26 0.026
synaptic transmission GO:0007268 329 0.026
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.026
female gamete generation GO:0007292 74 0.026
oocyte anterior posterior axis specification GO:0007314 2 0.026
regulation of cellular component biogenesis GO:0044087 181 0.025
fat cell differentiation GO:0045444 160 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.025
respiratory gaseous exchange GO:0007585 43 0.025
ribonucleoside catabolic process GO:0042454 206 0.025
nucleoside triphosphate catabolic process GO:0009143 205 0.025
regulation of innate immune response GO:0045088 91 0.025
muscle tissue development GO:0060537 308 0.025
negative regulation of proteolysis GO:0045861 74 0.025
establishment of synaptic vesicle localization GO:0097480 57 0.025
negative regulation of cellular component organization GO:0051129 194 0.024
organic cyclic compound catabolic process GO:1901361 295 0.024
positive regulation of transferase activity GO:0051347 167 0.024
cellular amine metabolic process GO:0044106 44 0.024
innate immune response GO:0045087 157 0.024
meiotic cell cycle GO:0051321 122 0.024
circadian regulation of gene expression GO:0032922 48 0.024
response to molecule of bacterial origin GO:0002237 143 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
regulation of defense response GO:0031347 233 0.024
regulation of cell cycle process GO:0010564 160 0.023
cellular amino acid metabolic process GO:0006520 103 0.023
response to organic cyclic compound GO:0014070 198 0.023
heart contraction GO:0060047 93 0.023
ribose phosphate metabolic process GO:0019693 291 0.023
tolerance induction to self antigen GO:0002513 4 0.023
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
peptidyl amino acid modification GO:0018193 336 0.023
heart process GO:0003015 94 0.023
uterus morphogenesis GO:0061038 2 0.023
positive regulation of protein kinase activity GO:0045860 144 0.023
regulation of mrna metabolic process GO:1903311 43 0.023
positive regulation of leukocyte differentiation GO:1902107 86 0.022
t cell differentiation GO:0030217 174 0.022
regulation of proteolysis GO:0030162 164 0.022
striated muscle tissue development GO:0014706 293 0.022
regulation of translation GO:0006417 71 0.022
regulation of kinase activity GO:0043549 249 0.022
oocyte axis specification GO:0007309 2 0.022
trna wobble base modification GO:0002097 2 0.022
embryonic skeletal system development GO:0048706 120 0.022
response to peptide hormone GO:0043434 127 0.022
gland development GO:0048732 330 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
demethylation GO:0070988 23 0.021
camera type eye development GO:0043010 266 0.021
gastrulation GO:0007369 116 0.021
nucleotide metabolic process GO:0009117 332 0.021
negative regulation of t cell proliferation GO:0042130 38 0.021
skeletal system morphogenesis GO:0048705 203 0.021
protein processing GO:0016485 163 0.020
response to lipopolysaccharide GO:0032496 128 0.020
lung development GO:0030324 164 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.019
retinal ganglion cell axon guidance GO:0031290 18 0.019
multi multicellular organism process GO:0044706 109 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
angiogenesis GO:0001525 201 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.019
regulation of secretion GO:0051046 274 0.019
maintenance of location GO:0051235 89 0.019
intracellular mrna localization GO:0008298 4 0.018
multicellular organism growth GO:0035264 161 0.018
protein dna complex subunit organization GO:0071824 28 0.018
cellular response to abiotic stimulus GO:0071214 56 0.018
lipid localization GO:0010876 126 0.018
b cell differentiation GO:0030183 78 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
synaptic vesicle transport GO:0048489 57 0.018
cochlear nucleus development GO:0021747 4 0.017
cellular homeostasis GO:0019725 240 0.017
multi organism behavior GO:0051705 62 0.017
transmembrane transport GO:0055085 412 0.017
skeletal muscle cell differentiation GO:0035914 66 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
intracellular protein transport GO:0006886 204 0.017
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.017
granulocyte differentiation GO:0030851 17 0.017
leukocyte proliferation GO:0070661 172 0.017
appendage development GO:0048736 166 0.017
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.017
positive regulation of protein catabolic process GO:0045732 60 0.016
wnt signaling pathway GO:0016055 188 0.016
blood circulation GO:0008015 195 0.016
response to organonitrogen compound GO:0010243 246 0.016
heart morphogenesis GO:0003007 178 0.016
b cell activation GO:0042113 161 0.016
leukocyte mediated immunity GO:0002443 174 0.016
negative regulation of smoothened signaling pathway GO:0045879 25 0.016
regulation of map kinase activity GO:0043405 120 0.016
cell substrate adhesion GO:0031589 130 0.016
lymphocyte homeostasis GO:0002260 64 0.016
cellular ketone metabolic process GO:0042180 84 0.016
response to light stimulus GO:0009416 135 0.016
tube closure GO:0060606 91 0.015
multi organism reproductive behavior GO:0044705 29 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
cytoplasmic transport GO:0016482 234 0.015
regulation of hydrolase activity GO:0051336 246 0.015
t cell receptor signaling pathway GO:0050852 46 0.015
immune response regulating signaling pathway GO:0002764 125 0.015
chromosome segregation GO:0007059 48 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
regulation of cytokine production GO:0001817 266 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
cell division GO:0051301 120 0.015
positive regulation of macroautophagy GO:0016239 3 0.015
apoptotic signaling pathway GO:0097190 306 0.015
gall bladder development GO:0061010 2 0.015
regulation of protein localization GO:0032880 231 0.015
face development GO:0060324 38 0.014
regulation of cellular component size GO:0032535 121 0.014
negative regulation of protein processing GO:0010955 79 0.014
ventricular cardiac myofibril assembly GO:0055005 3 0.014
mapk cascade GO:0000165 281 0.014
embryonic appendage morphogenesis GO:0035113 126 0.014
negative regulation of translation GO:0017148 22 0.014
b cell proliferation GO:0042100 53 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
muscle system process GO:0003012 141 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
regulation of inflammatory response GO:0050727 147 0.014
negative regulation of mitotic cell cycle GO:0045930 58 0.014
placenta development GO:0001890 140 0.014
respiratory system development GO:0060541 190 0.014
nucleobase containing small molecule metabolic process GO:0055086 352 0.013
natural killer cell differentiation GO:0001779 21 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
mitotic cell cycle process GO:1903047 159 0.013
axonogenesis GO:0007409 274 0.013
muscle adaptation GO:0043500 39 0.013
regulation of endocytosis GO:0030100 69 0.013
regulation of ossification GO:0030278 112 0.013
proteasomal protein catabolic process GO:0010498 98 0.013
regulation of dna templated transcription in response to stress GO:0043620 9 0.013
divalent inorganic cation transport GO:0072511 178 0.013
toll like receptor 3 signaling pathway GO:0034138 4 0.013
regulation of protein kinase activity GO:0045859 232 0.013
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.013
ameboidal type cell migration GO:0001667 128 0.013
embryonic digestive tract development GO:0048566 27 0.013
regulation of proteasomal protein catabolic process GO:0061136 46 0.013
chemotaxis GO:0006935 247 0.013
photoreceptor cell differentiation GO:0046530 52 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
peptidyl serine modification GO:0018209 83 0.012
sensory organ morphogenesis GO:0090596 242 0.012
negative regulation of secretion GO:0051048 61 0.012
actin cytoskeleton organization GO:0030036 220 0.012
regulation of myeloid cell differentiation GO:0045637 96 0.012
negative regulation of gene expression epigenetic GO:0045814 15 0.012
macrophage colony stimulating factor signaling pathway GO:0038145 2 0.012
neural tube closure GO:0001843 90 0.012
dna packaging GO:0006323 30 0.012
cell adhesion GO:0007155 329 0.012
epithelial cell development GO:0002064 159 0.012
leukocyte homeostasis GO:0001776 79 0.012
rna interference GO:0016246 2 0.012
positive regulation of rab gtpase activity GO:0032851 7 0.012
protein dealkylation GO:0008214 13 0.012
ribosomal small subunit biogenesis GO:0042274 4 0.012
regulation of chromatin organization GO:1902275 57 0.012
muscle cell differentiation GO:0042692 261 0.012
humoral immune response GO:0006959 57 0.012
t cell proliferation GO:0042098 120 0.012
negative regulation of histone modification GO:0031057 18 0.012
erk1 and erk2 cascade GO:0070371 77 0.012
regulation of neurotransmitter levels GO:0001505 87 0.012
intracellular receptor signaling pathway GO:0030522 74 0.012
phagocytosis GO:0006909 66 0.012
myotube cell development GO:0014904 60 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
mesenchymal cell differentiation GO:0048762 107 0.011
transforming growth factor beta2 production GO:0032906 2 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
cellular response to external stimulus GO:0071496 88 0.011
embryonic placenta development GO:0001892 98 0.011
regulation of mrna splicing via spliceosome GO:0048024 32 0.011
skeletal muscle organ development GO:0060538 163 0.011
macrophage differentiation GO:0030225 20 0.011
embryonic epithelial tube formation GO:0001838 130 0.011
regulation of b cell activation GO:0050864 81 0.011
positive regulation of b cell proliferation GO:0030890 24 0.011
positive regulation of wnt signaling pathway GO:0030177 45 0.011
regulation of organ morphogenesis GO:2000027 144 0.011
neural tube development GO:0021915 160 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
actin mediated cell contraction GO:0070252 15 0.011
regulation of protein processing GO:0070613 96 0.011
regulation of mitotic cell cycle phase transition GO:1901990 73 0.011
male meiosis i GO:0007141 16 0.011
positive regulation of ossification GO:0045778 47 0.011
cellular chemical homeostasis GO:0055082 215 0.011
regulation of ion transport GO:0043269 215 0.011
regulation of rna splicing GO:0043484 37 0.011
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.011
regulation of transmembrane transport GO:0034762 128 0.011
regulation of cell activation GO:0050865 289 0.011
negative regulation of cell activation GO:0050866 111 0.010
protein oligomerization GO:0051259 67 0.010
histone lysine methylation GO:0034968 50 0.010
regulation of chromosome organization GO:0033044 83 0.010
attachment of spindle microtubules to kinetochore GO:0008608 4 0.010
nucleoside metabolic process GO:0009116 246 0.010
protein maturation GO:0051604 176 0.010
tube formation GO:0035148 140 0.010
granulocyte activation GO:0036230 10 0.010

March7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011