Mus musculus

0 known processes

Akr1cl

aldo-keto reductase family 1, member C-like

(Aliases: AI451536,4921521F21Rik,AI503553)

Akr1cl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amine metabolic process GO:0009308 45 0.152
cation transmembrane transport GO:0098655 266 0.152
cellular ketone metabolic process GO:0042180 84 0.140
spermatid differentiation GO:0048515 115 0.138
steroid metabolic process GO:0008202 119 0.131
Mouse
lipid biosynthetic process GO:0008610 179 0.100
Mouse
inorganic cation transmembrane transport GO:0098662 207 0.096
positive regulation of cellular amine metabolic process GO:0033240 5 0.093
spermatogenesis GO:0007283 284 0.083
male gamete generation GO:0048232 285 0.079
cellular amine metabolic process GO:0044106 44 0.077
cellular amino acid metabolic process GO:0006520 103 0.076
dna metabolic process GO:0006259 303 0.074
spermatid development GO:0007286 108 0.072
ion transmembrane transport GO:0034220 361 0.069
cellular lipid metabolic process GO:0044255 323 0.068
regulation of cellular amine metabolic process GO:0033238 20 0.065
regulation of intracellular transport GO:0032386 159 0.065
diterpenoid metabolic process GO:0016101 24 0.062
regulation of cellular amino acid metabolic process GO:0006521 5 0.060
monocarboxylic acid metabolic process GO:0032787 191 0.060
inorganic ion transmembrane transport GO:0098660 234 0.057
cation transport GO:0006812 399 0.056
cellular macromolecule catabolic process GO:0044265 206 0.055
small molecule biosynthetic process GO:0044283 132 0.053
methylation GO:0032259 134 0.051
terpenoid metabolic process GO:0006721 25 0.049
regulation of cellular ketone metabolic process GO:0010565 66 0.045
single fertilization GO:0007338 82 0.044
fertilization GO:0009566 127 0.044
germ cell development GO:0007281 185 0.042
sensory perception GO:0007600 245 0.042
response to organic cyclic compound GO:0014070 198 0.041
macromolecule catabolic process GO:0009057 281 0.039
protein modification by small protein conjugation or removal GO:0070647 207 0.039
sensory organ morphogenesis GO:0090596 242 0.039
negative regulation of protein metabolic process GO:0051248 282 0.039
protein ubiquitination GO:0016567 171 0.039
benzene containing compound metabolic process GO:0042537 5 0.038
calcitriol biosynthetic process from calciol GO:0036378 3 0.037
positive regulation of protein modification process GO:0031401 299 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
reactive oxygen species metabolic process GO:0072593 84 0.036
isoprenoid metabolic process GO:0006720 29 0.036
regulation of cell cycle GO:0051726 281 0.036
peptidyl amino acid modification GO:0018193 336 0.035
organic acid biosynthetic process GO:0016053 86 0.034
oxidation reduction process GO:0055114 342 0.034
Mouse
regulation of defense response GO:0031347 233 0.033
cartilage development GO:0051216 140 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
connective tissue development GO:0061448 179 0.033
protein catabolic process GO:0030163 221 0.033
intracellular protein transport GO:0006886 204 0.032
lipid catabolic process GO:0016042 69 0.031
cellular protein catabolic process GO:0044257 155 0.030
response to organonitrogen compound GO:0010243 246 0.030
stem cell development GO:0048864 219 0.030
intrinsic apoptotic signaling pathway GO:0097193 132 0.030
protein modification by small protein conjugation GO:0032446 187 0.029
calcium ion transmembrane transport GO:0070588 85 0.029
progesterone metabolic process GO:0042448 4 0.029
negative regulation of protein modification process GO:0031400 163 0.028
positive regulation of apoptotic process GO:0043065 217 0.028
protein localization to organelle GO:0033365 185 0.028
regulation of kinase activity GO:0043549 249 0.028
cellular homeostasis GO:0019725 240 0.027
male gonad development GO:0008584 88 0.027
alcohol metabolic process GO:0006066 116 0.027
regulation of reactive oxygen species metabolic process GO:2000377 40 0.027
nucleocytoplasmic transport GO:0006913 139 0.027
macromolecule methylation GO:0043414 120 0.027
cellular response to lipid GO:0071396 145 0.026
regulation of mapk cascade GO:0043408 248 0.026
response to acid chemical GO:0001101 111 0.026
purine ribonucleotide metabolic process GO:0009150 290 0.026
chromatin modification GO:0016568 187 0.026
mapk cascade GO:0000165 281 0.025
regulation of system process GO:0044057 200 0.025
negative regulation of phosphorus metabolic process GO:0010563 184 0.025
chromatin organization GO:0006325 206 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
negative regulation of immune system process GO:0002683 209 0.024
regulation of establishment of protein localization GO:0070201 181 0.024
cellular response to gonadotropin stimulus GO:0071371 4 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
organic hydroxy compound metabolic process GO:1901615 203 0.024
meiotic nuclear division GO:0007126 115 0.024
stem cell differentiation GO:0048863 268 0.024
positive regulation of apoptotic signaling pathway GO:2001235 95 0.024
meiosis i GO:0007127 60 0.023
cellular ion homeostasis GO:0006873 165 0.023
homeostasis of number of cells GO:0048872 210 0.023
regulation of metal ion transport GO:0010959 106 0.023
rhythmic process GO:0048511 174 0.023
regulation of cellular component biogenesis GO:0044087 181 0.022
response to radiation GO:0009314 165 0.022
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.022
activation of mapk activity involved in innate immune response GO:0035419 2 0.022
regulation of ion transport GO:0043269 215 0.022
cellular protein complex assembly GO:0043623 116 0.022
cellular response to organic cyclic compound GO:0071407 87 0.022
cellular chemical homeostasis GO:0055082 215 0.022
oocyte axis specification GO:0007309 2 0.022
apoptotic signaling pathway GO:0097190 306 0.022
cellular response to hormone stimulus GO:0032870 150 0.021
nuclear import GO:0051170 95 0.021
protein targeting GO:0006605 143 0.021
neutral lipid metabolic process GO:0006638 57 0.021
regulation of multi organism process GO:0043900 111 0.021
mrna metabolic process GO:0016071 84 0.021
Mouse
steroid biosynthetic process GO:0006694 47 0.021
Mouse
dna methylation involved in gamete generation GO:0043046 15 0.020
ear development GO:0043583 200 0.020
purine containing compound metabolic process GO:0072521 311 0.020
protein processing GO:0016485 163 0.020
anion transport GO:0006820 177 0.020
pirna metabolic process GO:0034587 12 0.020
development of primary male sexual characteristics GO:0046546 88 0.020
gland development GO:0048732 330 0.019
regulation of blood pressure GO:0008217 93 0.019
regulation of protein kinase activity GO:0045859 232 0.019
endocytosis GO:0006897 168 0.019
synapsis GO:0007129 34 0.019
regulation of protein localization GO:0032880 231 0.019
maternal determination of anterior posterior axis embryo GO:0008358 2 0.019
regulation of transferase activity GO:0051338 263 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
regulation of lipid biosynthetic process GO:0046890 54 0.019
nuclear transport GO:0051169 139 0.019
regulation of cytoplasmic transport GO:1903649 112 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.019
response to light stimulus GO:0009416 135 0.018
carboxylic acid biosynthetic process GO:0046394 86 0.018
fatty acid metabolic process GO:0006631 121 0.018
regulation of intracellular protein transport GO:0033157 82 0.018
response to inorganic substance GO:0010035 96 0.018
prevention of polyspermy GO:0060468 4 0.018
c21 steroid hormone biosynthetic process GO:0006700 3 0.018
protein localization to nucleus GO:0034504 121 0.018
g protein coupled receptor signaling pathway GO:0007186 243 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
asymmetric stem cell division GO:0098722 3 0.018
regulation of organelle organization GO:0033043 289 0.018
organic anion transport GO:0015711 137 0.018
cellular response to dna damage stimulus GO:0006974 207 0.018
regulation of nucleocytoplasmic transport GO:0046822 73 0.018
regulation of proteolysis GO:0030162 164 0.018
cellular alcohol biosynthetic process GO:0044108 3 0.018
cellular response to organonitrogen compound GO:0071417 145 0.017
circulatory system process GO:0003013 197 0.017
oogenesis GO:0048477 56 0.017
modification dependent macromolecule catabolic process GO:0043632 133 0.017
positive regulation of cell death GO:0010942 224 0.017
rna processing GO:0006396 105 0.017
Mouse
divalent metal ion transport GO:0070838 172 0.017
response to oxidative stress GO:0006979 123 0.017
regulation of transmembrane transport GO:0034762 128 0.017
intracellular mrna localization GO:0008298 4 0.017
regulation of cellular response to growth factor stimulus GO:0090287 82 0.017
histone modification GO:0016570 159 0.016
covalent chromatin modification GO:0016569 163 0.016
mrna processing GO:0006397 63 0.016
Mouse
urogenital system development GO:0001655 261 0.016
regulation of cytokine production GO:0001817 266 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
inflammatory response GO:0006954 244 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
nucleotide metabolic process GO:0009117 332 0.016
establishment of protein localization to organelle GO:0072594 118 0.016
fat soluble vitamin biosynthetic process GO:0042362 4 0.016
protein import into nucleus GO:0006606 95 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
protein import GO:0017038 101 0.016
organic cyclic compound catabolic process GO:1901361 295 0.016
response to growth factor GO:0070848 198 0.016
retinoid metabolic process GO:0001523 24 0.016
meiotic cell cycle process GO:1903046 77 0.015
cellular response to antibiotic GO:0071236 4 0.015
development of primary female sexual characteristics GO:0046545 73 0.015
rna interference GO:0016246 2 0.015
maintenance of location GO:0051235 89 0.015
female gamete generation GO:0007292 74 0.015
cellular alcohol metabolic process GO:0044107 3 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
gonad development GO:0008406 141 0.015
glycerolipid metabolic process GO:0046486 122 0.015
proteasomal protein catabolic process GO:0010498 98 0.015
development of primary sexual characteristics GO:0045137 143 0.015
negative regulation of cell cycle GO:0045786 123 0.015
positive regulation of endopeptidase activity GO:0010950 43 0.015
regionalization GO:0003002 337 0.015
male meiosis GO:0007140 37 0.015
regulation of secretion GO:0051046 274 0.015
developmental maturation GO:0021700 193 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
protein maturation GO:0051604 176 0.015
negative regulation of nik nf kappab signaling GO:1901223 2 0.015
androgen biosynthetic process GO:0006702 4 0.015
carboxylic acid transport GO:0046942 100 0.015
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.015
signal transduction by p53 class mediator GO:0072331 51 0.015
regulation of phospholipid biosynthetic process GO:0071071 3 0.015
cellular lipid catabolic process GO:0044242 52 0.015
neuron death GO:0070997 154 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
cell adhesion GO:0007155 329 0.014
positive regulation of proteolysis GO:0045862 85 0.014
sperm egg recognition GO:0035036 37 0.014
cellular aldehyde metabolic process GO:0006081 12 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
neuron apoptotic process GO:0051402 142 0.014
protein methylation GO:0006479 81 0.014
cell type specific apoptotic process GO:0097285 268 0.014
protein kinase b signaling GO:0043491 74 0.014
oocyte construction GO:0007308 2 0.014
lung development GO:0030324 164 0.014
lipid transport GO:0006869 98 0.014
regulation of cell migration GO:0030334 219 0.014
chromosome organization involved in meiosis GO:0070192 39 0.014
organic hydroxy compound biosynthetic process GO:1901617 77 0.014
learning or memory GO:0007611 148 0.014
organelle fission GO:0048285 170 0.014
extracellular matrix organization GO:0030198 147 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
female gonad development GO:0008585 71 0.014
aromatic compound catabolic process GO:0019439 286 0.014
positive regulation of transferase activity GO:0051347 167 0.014
protein alkylation GO:0008213 81 0.014
purine nucleotide metabolic process GO:0006163 302 0.013
cellularization GO:0007349 1 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
cytokine production GO:0001816 319 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
divalent inorganic cation transport GO:0072511 178 0.013
metal ion homeostasis GO:0055065 189 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
epidermis development GO:0008544 187 0.013
digestive tract development GO:0048565 190 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
oocyte anterior posterior axis specification GO:0007314 2 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
alpha amino acid metabolic process GO:1901605 59 0.013
nuclear division GO:0000280 158 0.013
cation homeostasis GO:0055080 212 0.013
regulation of protein catabolic process GO:0042176 108 0.013
microtubule based process GO:0007017 236 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.013
response to drug GO:0042493 75 0.013
b cell activation GO:0042113 161 0.013
skin development GO:0043588 220 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
regulation of chromosome organization GO:0033044 83 0.013
triglyceride metabolic process GO:0006641 51 0.013
positive regulation of defense response GO:0031349 124 0.013
oocyte differentiation GO:0009994 35 0.012
leukocyte differentiation GO:0002521 342 0.012
sensory perception of chemical stimulus GO:0007606 51 0.012
regulation of secretion by cell GO:1903530 249 0.012
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.012
multi multicellular organism process GO:0044706 109 0.012
meiotic cell cycle GO:0051321 122 0.012
positive regulation of innate immune response GO:0045089 80 0.012
regulation of feeding behavior GO:0060259 3 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
locomotory behavior GO:0007626 195 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
detection of stimulus GO:0051606 84 0.012
transition metal ion transport GO:0000041 38 0.012
sensory perception of mechanical stimulus GO:0050954 107 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.012
t cell activation GO:0042110 289 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
respiratory tube development GO:0030323 167 0.012
single organism nuclear import GO:1902593 95 0.012
mesodermal cell migration GO:0008078 4 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
alcohol biosynthetic process GO:0046165 43 0.012
stem cell proliferation GO:0072089 117 0.012
i kappab kinase nf kappab signaling GO:0007249 85 0.012
response to peptide GO:1901652 136 0.012
dephosphorylation GO:0016311 129 0.012
vitamin d biosynthetic process GO:0042368 3 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
sterol homeostasis GO:0055092 45 0.011
dna conformation change GO:0071103 37 0.011
cellular response to oxidative stress GO:0034599 76 0.011
cellular response to acid chemical GO:0071229 68 0.011
positive regulation of transmembrane transport GO:0034764 29 0.011
transmembrane transport GO:0055085 412 0.011
nucleoside phosphate metabolic process GO:0006753 338 0.011
skeletal system development GO:0001501 356 0.011
sequestering of metal ion GO:0051238 19 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
fibronectin dependent thymocyte migration GO:0072681 1 0.011
dna modification GO:0006304 50 0.011
cell division GO:0051301 120 0.011
oligopeptide transmembrane transport GO:0035672 4 0.011
response to steroid hormone GO:0048545 56 0.011
carbohydrate transport GO:0008643 62 0.011
protein oligomerization GO:0051259 67 0.011
carbohydrate metabolic process GO:0005975 230 0.011
regulation of protein maturation GO:1903317 96 0.011
monocarboxylic acid biosynthetic process GO:0072330 61 0.011
regulation of hormone levels GO:0010817 211 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
cofactor metabolic process GO:0051186 80 0.011
regulation of protein targeting GO:1903533 61 0.011
learning GO:0007612 98 0.011
positive regulation of intracellular transport GO:0032388 70 0.011
adult behavior GO:0030534 135 0.011
calcium ion transport GO:0006816 159 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
nitrogen compound transport GO:0071705 271 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
regulation of protein kinase b signaling GO:0051896 56 0.011
positive regulation of fibronectin dependent thymocyte migration GO:2000415 1 0.011
hormone metabolic process GO:0042445 86 0.011
eosinophil migration GO:0072677 3 0.010
multicellular organism growth GO:0035264 161 0.010
negative regulation of molecular function GO:0044092 258 0.010
positive regulation of cytokine production GO:0001819 174 0.010
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.010
positive regulation of protein kinase b signaling GO:0051897 32 0.010
developmental growth involved in morphogenesis GO:0060560 138 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
cytokine mediated signaling pathway GO:0019221 115 0.010
organophosphate catabolic process GO:0046434 232 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
detection of abiotic stimulus GO:0009582 60 0.010
extracellular matrix dependent thymocyte migration GO:0072680 1 0.010
response to fructose GO:0009750 2 0.010
cellular response to abiotic stimulus GO:0071214 56 0.010
regulation of lipid metabolic process GO:0019216 118 0.010
positive regulation of ubiquitin protein transferase activity GO:0051443 4 0.010
regulation of cell cycle process GO:0010564 160 0.010
male sex differentiation GO:0046661 109 0.010
regulation of steroid hormone biosynthetic process GO:0090030 4 0.010
lipid localization GO:0010876 126 0.010
cellular response to cadmium ion GO:0071276 3 0.010
regulation of apoptotic signaling pathway GO:2001233 197 0.010
purine nucleoside metabolic process GO:0042278 241 0.010
innate immune response GO:0045087 157 0.010
regulation of cellular catabolic process GO:0031329 242 0.010
peptidyl lysine modification GO:0018205 77 0.010

Akr1cl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.032
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012
sensory system disease DOID:0050155 0 0.010