Mus musculus

0 known processes

Mcfd2

multiple coagulation factor deficiency 2

(Aliases: 1810021C21Rik,Lman1ip,F5f8d,Sdnsf)

Mcfd2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular protein catabolic process GO:0044257 155 0.106
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.105
cellular amino acid metabolic process GO:0006520 103 0.070
male gamete generation GO:0048232 285 0.060
protein catabolic process GO:0030163 221 0.058
cytoplasmic transport GO:0016482 234 0.048
response to topologically incorrect protein GO:0035966 25 0.045
cytokine production GO:0001816 319 0.044
cellular response to topologically incorrect protein GO:0035967 25 0.042
response to unfolded protein GO:0006986 21 0.042
amine metabolic process GO:0009308 45 0.038
macromolecule catabolic process GO:0009057 281 0.038
retrograde vesicle mediated transport golgi to er GO:0006890 1 0.036
spermatogenesis GO:0007283 284 0.036
lymphocyte differentiation GO:0030098 242 0.036
regulation of protein localization GO:0032880 231 0.035
regulation of cytokine production GO:0001817 266 0.035
immune effector process GO:0002252 321 0.035
cellular macromolecule catabolic process GO:0044265 206 0.035
regulation of leukocyte differentiation GO:1902105 159 0.034
regulation of lymphocyte activation GO:0051249 240 0.033
oxidation reduction process GO:0055114 342 0.033
organic hydroxy compound metabolic process GO:1901615 203 0.033
apoptotic signaling pathway GO:0097190 306 0.033
regulation of secretion GO:0051046 274 0.032
regulation of cell activation GO:0050865 289 0.032
placenta development GO:0001890 140 0.031
regulation of establishment of protein localization GO:0070201 181 0.031
skeletal system development GO:0001501 356 0.030
cellular response to biotic stimulus GO:0071216 92 0.030
cellular ketone metabolic process GO:0042180 84 0.030
t cell activation GO:0042110 289 0.029
transmembrane transport GO:0055085 412 0.029
t cell differentiation GO:0030217 174 0.028
cellular amine metabolic process GO:0044106 44 0.028
intra golgi vesicle mediated transport GO:0006891 1 0.027
glycoprotein metabolic process GO:0009100 116 0.027
leukocyte differentiation GO:0002521 342 0.027
regulation of t cell activation GO:0050863 170 0.027
cation transport GO:0006812 399 0.027
endoplasmic reticulum unfolded protein response GO:0030968 19 0.027
regulation of apoptotic signaling pathway GO:2001233 197 0.026
cation homeostasis GO:0055080 212 0.026
endomembrane system organization GO:0010256 147 0.025
protein modification by small protein conjugation or removal GO:0070647 207 0.025
protein ubiquitination GO:0016567 171 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
ubiquitin dependent protein catabolic process GO:0006511 129 0.023
positive regulation of protein modification process GO:0031401 299 0.023
regulation of intracellular transport GO:0032386 159 0.022
cation transmembrane transport GO:0098655 266 0.022
response to endoplasmic reticulum stress GO:0034976 53 0.022
male sex differentiation GO:0046661 109 0.021
protein modification by small protein conjugation GO:0032446 187 0.021
inorganic ion transmembrane transport GO:0098660 234 0.021
cellular response to molecule of bacterial origin GO:0071219 83 0.021
regulation of multi organism process GO:0043900 111 0.021
positive regulation of cell activation GO:0050867 158 0.020
innate immune response GO:0045087 157 0.020
gland development GO:0048732 330 0.020
nucleotide metabolic process GO:0009117 332 0.020
organonitrogen compound catabolic process GO:1901565 264 0.020
nitrogen compound transport GO:0071705 271 0.020
metal ion homeostasis GO:0055065 189 0.020
monocarboxylic acid metabolic process GO:0032787 191 0.020
small molecule biosynthetic process GO:0044283 132 0.020
multi multicellular organism process GO:0044706 109 0.020
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.020
cellular response to lipopolysaccharide GO:0071222 77 0.020
inflammatory response GO:0006954 244 0.020
pyridine containing compound catabolic process GO:0072526 4 0.020
regulation of cellular amine metabolic process GO:0033238 20 0.019
lymphocyte mediated immunity GO:0002449 139 0.019
positive regulation of interleukin 6 secretion GO:2000778 1 0.019
regulation of lymphocyte differentiation GO:0045619 107 0.019
positive regulation of secretion by cell GO:1903532 114 0.019
response to lipopolysaccharide GO:0032496 128 0.019
carbohydrate metabolic process GO:0005975 230 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.018
aromatic compound catabolic process GO:0019439 286 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
proteasomal protein catabolic process GO:0010498 98 0.018
localization within membrane GO:0051668 4 0.018
peptidyl amino acid modification GO:0018193 336 0.018
copii coated vesicle budding GO:0090114 2 0.018
regulation of organelle organization GO:0033043 289 0.018
golgi vesicle transport GO:0048193 30 0.018
ion transmembrane transport GO:0034220 361 0.018
regulation of protein transport GO:0051223 163 0.018
cellular response to lipid GO:0071396 145 0.017
modification dependent protein catabolic process GO:0019941 133 0.017
regulation of response to wounding GO:1903034 189 0.017
carboxylic acid biosynthetic process GO:0046394 86 0.017
negative regulation of molecular function GO:0044092 258 0.017
regulation of secretion by cell GO:1903530 249 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
leukocyte mediated immunity GO:0002443 174 0.017
regulation of cellular amino acid metabolic process GO:0006521 5 0.017
negative regulation of cytokine production GO:0001818 84 0.017
protein localization to organelle GO:0033365 185 0.017
cellular homeostasis GO:0019725 240 0.017
mapk cascade GO:0000165 281 0.016
intracellular protein transport GO:0006886 204 0.016
extracellular matrix organization GO:0030198 147 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
cellular modified amino acid metabolic process GO:0006575 63 0.016
l ascorbic acid metabolic process GO:0019852 4 0.016
positive regulation of lymphocyte activation GO:0051251 140 0.016
er nucleus signaling pathway GO:0006984 27 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
response to molecule of bacterial origin GO:0002237 143 0.015
protein glycosylation GO:0006486 55 0.015
lipid transport GO:0006869 98 0.015
nuclear import GO:0051170 95 0.015
heterocycle catabolic process GO:0046700 280 0.015
adaptive immune response GO:0002250 155 0.015
homeostasis of number of cells GO:0048872 210 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
protein targeting GO:0006605 143 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
response to organic cyclic compound GO:0014070 198 0.015
cellular chemical homeostasis GO:0055082 215 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
membrane lipid biosynthetic process GO:0046467 32 0.014
interleukin 6 secretion GO:0072604 3 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.014
cellular ion homeostasis GO:0006873 165 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
positive regulation of apoptotic signaling pathway GO:2001235 95 0.014
cargo loading into vesicle GO:0035459 3 0.014
renal system development GO:0072001 225 0.014
wnt signaling pathway GO:0016055 188 0.014
regulation of defense response GO:0031347 233 0.014
regulation of mapk cascade GO:0043408 248 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
regulation of reproductive process GO:2000241 66 0.014
positive regulation of leukocyte differentiation GO:1902107 86 0.014
positive regulation of cellular amine metabolic process GO:0033240 5 0.014
extracellular structure organization GO:0043062 148 0.014
regulation of cellular ketone metabolic process GO:0010565 66 0.014
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.014
cellular response to thyroid hormone stimulus GO:0097067 1 0.014
protein secretion GO:0009306 111 0.014
maintenance of location GO:0051235 89 0.014
amide transport GO:0042886 138 0.014
positive regulation of transferase activity GO:0051347 167 0.014
transition metal ion homeostasis GO:0055076 54 0.014
regulation of kinase activity GO:0043549 249 0.013
regulation of hydrolase activity GO:0051336 246 0.013
positive regulation of t cell activation GO:0050870 101 0.013
cellular response to external stimulus GO:0071496 88 0.013
cellular response to starvation GO:0009267 57 0.013
regulation of t cell differentiation GO:0045580 83 0.013
camera type eye development GO:0043010 266 0.013
respiratory system development GO:0060541 190 0.013
nucleoside catabolic process GO:0009164 206 0.013
t cell proliferation GO:0042098 120 0.013
purine containing compound metabolic process GO:0072521 311 0.013
regulation of protein secretion GO:0050708 82 0.013
response to inorganic substance GO:0010035 96 0.013
positive regulation of response to wounding GO:1903036 66 0.013
organic hydroxy compound transport GO:0015850 93 0.012
regulation of membrane potential GO:0042391 192 0.012
nuclear transport GO:0051169 139 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
cytokine secretion GO:0050663 72 0.012
response to acid chemical GO:0001101 111 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
intracellular sterol transport GO:0032366 3 0.012
interleukin 6 production GO:0032635 58 0.012
sphingolipid biosynthetic process GO:0030148 26 0.012
intracellular cholesterol transport GO:0032367 3 0.012
leukocyte migration GO:0050900 124 0.012
lipid biosynthetic process GO:0008610 179 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
regulation of hormone levels GO:0010817 211 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
epidermis development GO:0008544 187 0.011
action potential GO:0001508 78 0.011
organic acid biosynthetic process GO:0016053 86 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
male gonad development GO:0008584 88 0.011
regulation of cellular response to stress GO:0080135 159 0.011
glucose homeostasis GO:0042593 128 0.011
cell type specific apoptotic process GO:0097285 268 0.011
b cell differentiation GO:0030183 78 0.011
sulfur compound metabolic process GO:0006790 100 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
maternal placenta development GO:0001893 20 0.011
response to nutrient levels GO:0031667 109 0.011
cell killing GO:0001906 67 0.011
hepaticobiliary system development GO:0061008 67 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.011
divalent inorganic cation transport GO:0072511 178 0.011
water soluble vitamin biosynthetic process GO:0042364 3 0.011
response to oxidative stress GO:0006979 123 0.011
membrane organization GO:0061024 245 0.011
striated muscle tissue development GO:0014706 293 0.011
protein import GO:0017038 101 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
transmission of nerve impulse GO:0019226 76 0.011
sequestering of metal ion GO:0051238 19 0.011
ceramide biosynthetic process GO:0046513 20 0.011
progesterone metabolic process GO:0042448 4 0.011
anatomical structure homeostasis GO:0060249 145 0.011
ribose phosphate metabolic process GO:0019693 291 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
protein maturation GO:0051604 176 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010
response to monosaccharide GO:0034284 67 0.010
multicellular organismal signaling GO:0035637 91 0.010
peptide metabolic process GO:0006518 46 0.010
b cell activation GO:0042113 161 0.010
liver development GO:0001889 66 0.010
inorganic cation transmembrane transport GO:0098662 207 0.010
regulation of epithelial cell proliferation GO:0050678 141 0.010
positive regulation of inflammatory response GO:0050729 47 0.010
cellular response to extracellular stimulus GO:0031668 81 0.010
4 hydroxyproline metabolic process GO:0019471 5 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.010
regulation of homeostatic process GO:0032844 182 0.010
er to golgi vesicle mediated transport GO:0006888 11 0.010
regulation of transferase activity GO:0051338 263 0.010
leukocyte mediated cytotoxicity GO:0001909 62 0.010
negative regulation of cell activation GO:0050866 111 0.010
regulation of transporter activity GO:0032409 57 0.010

Mcfd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
inherited metabolic disorder DOID:655 0 0.054
disease of metabolism DOID:0014667 0 0.054
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
sensory system disease DOID:0050155 0 0.017
eye disease DOID:5614 0 0.017
eye and adnexa disease DOID:1492 0 0.017
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.016
lysosomal storage disease DOID:3211 0 0.011