Mus musculus

63 known processes

Akr1c6

aldo-keto reductase family 1, member C6

(Aliases: 3alpha-HSD,Hsd17b5,Akr1c1)

Akr1c6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001998 3 0.965
naphthalene metabolic process GO:0018931 1 0.883
cellular response to food GO:0071240 1 0.882
response to phenylpropanoid GO:0080184 22 0.832
naphthalene containing compound metabolic process GO:0090420 1 0.822
cellular response to testosterone stimulus GO:0071394 1 0.819
renal tubular secretion GO:0097254 2 0.777
estrogen secretion GO:0035937 1 0.770
positive regulation of steroid hormone secretion GO:2000833 2 0.766
response to stilbenoid GO:0035634 22 0.749
alcohol metabolic process GO:0006066 116 0.747
positive regulation of estrogen secretion GO:2000863 1 0.725
oxidation reduction process GO:0055114 342 0.698
monocarboxylic acid metabolic process GO:0032787 191 0.647
Human
small molecule biosynthetic process GO:0044283 132 0.639
regulation of estrogen secretion GO:2000861 1 0.637
oxidative demethylation GO:0070989 1 0.629
cellular lipid metabolic process GO:0044255 323 0.617
Human
glucuronate metabolic process GO:0019585 2 0.612
fatty acid metabolic process GO:0006631 121 0.594
Human
cofactor metabolic process GO:0051186 80 0.581
Human
cellular response to hormone stimulus GO:0032870 150 0.578
Human
response to testosterone GO:0033574 3 0.572
response to organic cyclic compound GO:0014070 198 0.567
Rat
cellular response to cadmium ion GO:0071276 3 0.564
renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure GO:0003072 5 0.553
protein maturation GO:0051604 176 0.514
negative regulation of gluconeogenesis GO:0045721 9 0.498
terpenoid metabolic process GO:0006721 25 0.490
diterpenoid metabolic process GO:0016101 24 0.468
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 4 0.451
response to peptide GO:1901652 136 0.434
regulation of protein maturation GO:1903317 96 0.421
fat soluble vitamin biosynthetic process GO:0042362 4 0.414
cellular alcohol metabolic process GO:0044107 3 0.412
icosanoid metabolic process GO:0006690 33 0.398
Human
medium chain fatty acid metabolic process GO:0051791 1 0.368
organic hydroxy compound metabolic process GO:1901615 203 0.363
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.362
secondary alcohol metabolic process GO:1902652 3 0.352
cellular ketone metabolic process GO:0042180 84 0.351
Human
response to peptide hormone GO:0043434 127 0.348
amine metabolic process GO:0009308 45 0.336
protein processing GO:0016485 163 0.335
porphyrin containing compound metabolic process GO:0006778 22 0.333
response to organonitrogen compound GO:0010243 246 0.323
regulation of hormone levels GO:0010817 211 0.323
Human
cellular response to steroid hormone stimulus GO:0071383 33 0.306
cellular response to insulin stimulus GO:0032869 78 0.304
lipid biosynthetic process GO:0008610 179 0.299
negative regulation of lipid metabolic process GO:0045833 30 0.298
negative regulation of iron ion transport GO:0034757 1 0.290
regulation of protein activation cascade GO:2000257 7 0.289
activation of immune response GO:0002253 138 0.283
response to molecule of bacterial origin GO:0002237 143 0.279
cellular response to lipid GO:0071396 145 0.273
secondary metabolite catabolic process GO:0090487 1 0.272
lipid localization GO:0010876 126 0.269
regulation of protein processing GO:0070613 96 0.263
progesterone metabolic process GO:0042448 4 0.260
Human
vitamin d3 metabolic process GO:0070640 3 0.260
vitamin d biosynthetic process GO:0042368 3 0.258
vitamin metabolic process GO:0006766 23 0.251
regulation of secretion GO:0051046 274 0.250
heme metabolic process GO:0042168 16 0.246
negative regulation of hydrolase activity GO:0051346 71 0.242
neutral lipid metabolic process GO:0006638 57 0.240
arachidonic acid metabolic process GO:0019369 14 0.237
regulation of cellular ketone metabolic process GO:0010565 66 0.229
response to metal ion GO:0010038 47 0.228
cellular alcohol biosynthetic process GO:0044108 3 0.227
glycerolipid metabolic process GO:0046486 122 0.220
cellular response to inorganic substance GO:0071241 37 0.219
fat soluble vitamin metabolic process GO:0006775 11 0.216
isoprenoid metabolic process GO:0006720 29 0.215
regulation of reactive oxygen species metabolic process GO:2000377 40 0.215
toxin catabolic process GO:0009407 1 0.215
regulation of inflammatory response GO:0050727 147 0.214
toxin metabolic process GO:0009404 5 0.213
steroid metabolic process GO:0008202 119 0.212
cellular response to peptide GO:1901653 92 0.199
uronic acid metabolic process GO:0006063 2 0.190
regulation of proteolysis GO:0030162 164 0.189
negative regulation of protein metabolic process GO:0051248 282 0.186
response to cadmium ion GO:0046686 8 0.185
regulation of cholesterol metabolic process GO:0090181 14 0.181
sterol metabolic process GO:0016125 58 0.177
negative regulation of protein processing GO:0010955 79 0.176
cytokine production GO:0001816 319 0.173
lipid catabolic process GO:0016042 69 0.172
secondary metabolic process GO:0019748 18 0.170
Human
positive regulation of plasminogen activation GO:0010756 2 0.170
drug metabolic process GO:0017144 4 0.169
cellular response to metal ion GO:0071248 31 0.168
maintenance of location GO:0051235 89 0.168
pigment metabolic process GO:0042440 32 0.164
insulin receptor signaling pathway GO:0008286 49 0.164
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.163
response to drug GO:0042493 75 0.163
Rat
hormone metabolic process GO:0042445 86 0.161
Human
response to lipopolysaccharide GO:0032496 128 0.161
short chain fatty acid metabolic process GO:0046459 6 0.160
unsaturated fatty acid metabolic process GO:0033559 31 0.160
Human
monosaccharide metabolic process GO:0005996 106 0.159
cellular response to peptide hormone stimulus GO:0071375 92 0.153
response to inorganic substance GO:0010035 96 0.150
circulatory system process GO:0003013 197 0.143
calcitriol biosynthetic process from calciol GO:0036378 3 0.141
complement activation GO:0006956 16 0.138
response to nutrient levels GO:0031667 109 0.138
immune effector process GO:0002252 321 0.137
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.135
alcohol biosynthetic process GO:0046165 43 0.134
regulation of defense response GO:0031347 233 0.130
nitrogen compound transport GO:0071705 271 0.130
positive regulation of hormone secretion GO:0046887 38 0.129
fatty acid derivative metabolic process GO:1901568 33 0.127
Human
regulation of complement activation GO:0030449 7 0.127
sulfate assimilation GO:0000103 3 0.126
positive regulation of secretion GO:0051047 130 0.126
response to insulin GO:0032868 100 0.126
negative regulation of molecular function GO:0044092 258 0.125
cellular response to ketone GO:1901655 12 0.125
regulation of systemic arterial blood pressure GO:0003073 61 0.124
organic hydroxy compound biosynthetic process GO:1901617 77 0.123
tetrapyrrole metabolic process GO:0033013 22 0.121
protein activation cascade GO:0072376 19 0.121
negative regulation of proteolysis GO:0045861 74 0.121
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.120
response to steroid hormone GO:0048545 56 0.119
Rat
cellular amino acid metabolic process GO:0006520 103 0.119
positive regulation of phagocytosis GO:0050766 26 0.116
regulation of hydrolase activity GO:0051336 246 0.116
linoleic acid metabolic process GO:0043651 6 0.115
hexose biosynthetic process GO:0019319 39 0.111
carbohydrate metabolic process GO:0005975 230 0.110
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.107
xenobiotic catabolic process GO:0042178 1 0.107
regulation of peptidase activity GO:0052547 96 0.106
cellular amine metabolic process GO:0044106 44 0.105
regulation of apoptotic signaling pathway GO:2001233 197 0.105
innate immune response GO:0045087 157 0.105
reactive oxygen species metabolic process GO:0072593 84 0.104
female sex differentiation GO:0046660 84 0.104
negative regulation of protein maturation GO:1903318 79 0.104
negative regulation of cellular protein metabolic process GO:0032269 247 0.104
positive regulation of endocytosis GO:0045807 42 0.102
development of primary female sexual characteristics GO:0046545 73 0.101
monosaccharide biosynthetic process GO:0046364 44 0.101
organic acid biosynthetic process GO:0016053 86 0.100
cellular chemical homeostasis GO:0055082 215 0.100
vasoconstriction GO:0042310 27 0.097
positive regulation of lipid transport GO:0032370 22 0.096
primary alcohol metabolic process GO:0034308 11 0.095
cholesterol metabolic process GO:0008203 56 0.091
negative regulation of fibrinolysis GO:0051918 1 0.091
female gonad development GO:0008585 71 0.090
carboxylic acid biosynthetic process GO:0046394 86 0.089
regulation of glucose metabolic process GO:0010906 60 0.089
cation transport GO:0006812 399 0.088
lipid storage GO:0019915 36 0.087
positive regulation of protein activation cascade GO:2000259 2 0.086
hormone secretion GO:0046879 128 0.086
regulation of gluconeogenesis GO:0006111 30 0.085
regulation of secretion by cell GO:1903530 249 0.084
response to molecule of fungal origin GO:0002238 4 0.083
monocarboxylic acid biosynthetic process GO:0072330 61 0.082
reactive oxygen species biosynthetic process GO:1903409 8 0.082
long chain fatty acid metabolic process GO:0001676 26 0.081
regulation of protein secretion GO:0050708 82 0.081
progesterone biosynthetic process GO:0006701 1 0.081
regulation of blood vessel size by renin angiotensin GO:0002034 5 0.078
humoral immune response GO:0006959 57 0.076
organonitrogen compound catabolic process GO:1901565 264 0.076
acylglycerol metabolic process GO:0006639 55 0.076
negative regulation of peptidase activity GO:0010466 46 0.075
cellular homeostasis GO:0019725 240 0.075
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.075
diterpenoid biosynthetic process GO:0016102 7 0.075
hexose metabolic process GO:0019318 98 0.074
regulation of cytokine production GO:0001817 266 0.074
inter male aggressive behavior GO:0002121 3 0.074
cellular response to organonitrogen compound GO:0071417 145 0.073
regulation of protein kinase c activity GO:1900019 1 0.072
testosterone biosynthetic process GO:0061370 2 0.072
carbohydrate biosynthetic process GO:0016051 74 0.072
regulation of protein kinase activity GO:0045859 232 0.072
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.071
inflammatory response GO:0006954 244 0.071
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.071
regulation of response to wounding GO:1903034 189 0.071
negative regulation of endopeptidase activity GO:0010951 44 0.070
cellular response to alcohol GO:0097306 23 0.070
regulation of cellular amino acid metabolic process GO:0006521 5 0.069
regulation of homeostatic process GO:0032844 182 0.068
gluconeogenesis GO:0006094 39 0.068
phagocytosis GO:0006909 66 0.067
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.067
regulation of carbohydrate biosynthetic process GO:0043255 40 0.067
androgen biosynthetic process GO:0006702 4 0.066
cation homeostasis GO:0055080 212 0.066
apoptotic signaling pathway GO:0097190 306 0.065
myeloid cell differentiation GO:0030099 233 0.065
regulation of vesicle mediated transport GO:0060627 139 0.065
positive regulation of apoptotic process GO:0043065 217 0.064
regulation of hormone secretion GO:0046883 88 0.064
regulation of lymphocyte mediated immunity GO:0002706 84 0.064
positive regulation of protein kinase c activity GO:1900020 1 0.064
regulation of kinase activity GO:0043549 249 0.063
sensory perception GO:0007600 245 0.063
cytokine metabolic process GO:0042107 71 0.062
short chain fatty acid catabolic process GO:0019626 2 0.060
dibenzo p dioxin metabolic process GO:0018894 1 0.060
anion transport GO:0006820 177 0.060
regulation of establishment of protein localization GO:0070201 181 0.060
organic cyclic compound catabolic process GO:1901361 295 0.059
cellular nitrogen compound catabolic process GO:0044270 280 0.059
modification of morphology or physiology of other organism GO:0035821 18 0.058
acute inflammatory response GO:0002526 41 0.058
negative regulation of cellular carbohydrate metabolic process GO:0010677 19 0.058
ion transmembrane transport GO:0034220 361 0.058
cellular response to organic cyclic compound GO:0071407 87 0.058
multicellular organismal homeostasis GO:0048871 164 0.057
regulation of cell activation GO:0050865 289 0.055
blood coagulation GO:0007596 76 0.055
negative regulation of carbohydrate metabolic process GO:0045912 19 0.055
amino acid transmembrane transport GO:0003333 37 0.054
regulation of cellular amine metabolic process GO:0033238 20 0.054
positive regulation of mapk cascade GO:0043410 170 0.053
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.053
cell killing GO:0001906 67 0.053
blood circulation GO:0008015 195 0.053
cellular lipid catabolic process GO:0044242 52 0.053
regulation of system process GO:0044057 200 0.053
regulation of humoral immune response GO:0002920 22 0.052
response to chromate GO:0046687 1 0.052
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.052
positive regulation of activation of membrane attack complex GO:0001970 2 0.052
polyol biosynthetic process GO:0046173 13 0.052
cellular response to starvation GO:0009267 57 0.052
cellular response to cytokine stimulus GO:0071345 189 0.051
small molecule catabolic process GO:0044282 71 0.051
primary alcohol catabolic process GO:0034310 2 0.050
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.050
positive regulation of systemic arterial blood pressure GO:0003084 9 0.050
positive regulation of secretion by cell GO:1903532 114 0.050
regulation of protein transport GO:0051223 163 0.049
amide transport GO:0042886 138 0.049
glucose metabolic process GO:0006006 92 0.049
macromolecule glycosylation GO:0043413 55 0.049
terpenoid biosynthetic process GO:0016114 7 0.049
transmembrane transport GO:0055085 412 0.049
drug catabolic process GO:0042737 2 0.048
regulation of mapk cascade GO:0043408 248 0.048
fibrinolysis GO:0042730 3 0.047
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 15 0.047
regulation of immunological synapse formation GO:2000520 2 0.047
rhythmic process GO:0048511 174 0.046
anion transmembrane transport GO:0098656 71 0.045
negative regulation of complement activation GO:0045916 3 0.045
regulation of complement activation classical pathway GO:0030450 1 0.044
leukocyte mediated immunity GO:0002443 174 0.044
positive regulation of complement activation GO:0045917 2 0.044
protein glycosylation GO:0006486 55 0.044
reactive nitrogen species metabolic process GO:2001057 0 0.044
retinoid metabolic process GO:0001523 24 0.043
positive regulation of programmed cell death GO:0043068 218 0.043
regulation of peptide transport GO:0090087 91 0.042
renal system process GO:0003014 48 0.042
olfactory learning GO:0008355 2 0.041
positive regulation of protein modification process GO:0031401 299 0.041
positive regulation of lipid metabolic process GO:0045834 40 0.041
regulation of cellular catabolic process GO:0031329 242 0.041
camera type eye development GO:0043010 266 0.040
retinoic acid metabolic process GO:0042573 12 0.040
cellular response to carbohydrate stimulus GO:0071322 50 0.040
response to oxidative stress GO:0006979 123 0.039
organic hydroxy compound catabolic process GO:1901616 25 0.039
regulation of endopeptidase activity GO:0052548 89 0.039
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.039
regulation of multi organism process GO:0043900 111 0.039
establishment of blood nerve barrier GO:0008065 3 0.037
positive regulation of cell death GO:0010942 224 0.037
ovarian follicle rupture GO:0001543 2 0.037
myeloid leukocyte differentiation GO:0002573 119 0.037
lipid transport GO:0006869 98 0.036
cellular carbohydrate metabolic process GO:0044262 119 0.036
regulation of lipid biosynthetic process GO:0046890 54 0.036
sensory perception of chemical stimulus GO:0007606 51 0.035
regulation of protein localization GO:0032880 231 0.035
mapk cascade GO:0000165 281 0.035
mitochondrion organization GO:0007005 134 0.035
regulation of interleukin 8 production GO:0032677 3 0.035
sensory perception of smell GO:0007608 26 0.034
insulin secretion GO:0030073 89 0.034
cofactor transport GO:0051181 4 0.034
negative regulation of immune system process GO:0002683 209 0.034
extrinsic apoptotic signaling pathway GO:0097191 126 0.033
positive regulation of protein kinase activity GO:0045860 144 0.033
regulation of tube size GO:0035150 57 0.033
activation of membrane attack complex GO:0001905 4 0.033
response to iron ion GO:0010039 4 0.033
cellular response to nutrient levels GO:0031669 64 0.033
astrocyte activation GO:0048143 2 0.033
growth involved in symbiotic interaction GO:0044110 23 0.033
peptidyl amino acid modification GO:0018193 336 0.033
defense response to other organism GO:0098542 197 0.032
regulation of leukocyte mediated immunity GO:0002703 104 0.032
regulation of insulin receptor signaling pathway GO:0046626 21 0.032
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.032
negative regulation of serine type endopeptidase activity GO:1900004 2 0.031
endocrine process GO:0050886 39 0.031
response to transition metal nanoparticle GO:1990267 11 0.031
cellular response to monosaccharide stimulus GO:0071326 47 0.031
lymphocyte mediated immunity GO:0002449 139 0.030
energy reserve metabolic process GO:0006112 39 0.030
regulation of plasminogen activation GO:0010755 4 0.030
tyrosine metabolic process GO:0006570 4 0.030
retinal metabolic process GO:0042574 5 0.030
energy derivation by oxidation of organic compounds GO:0015980 77 0.030
regulation of blood vessel size GO:0050880 56 0.030
renal system development GO:0072001 225 0.029
cellular response to corticosteroid stimulus GO:0071384 13 0.029
cellular response to hexose stimulus GO:0071331 47 0.029
exogenous drug catabolic process GO:0042738 1 0.029
regulation of endocytosis GO:0030100 69 0.029
glycoprotein biosynthetic process GO:0009101 89 0.029
positive regulation of acute inflammatory response to antigenic stimulus GO:0002866 7 0.029
regulation of renal output by angiotensin GO:0002019 2 0.029
negative regulation of macrophage apoptotic process GO:2000110 3 0.029
thermosensory behavior GO:0040040 1 0.028
response to estrogen GO:0043627 24 0.028
Rat
defense response to bacterium GO:0042742 119 0.028
morphogenesis of a branching epithelium GO:0061138 193 0.028
regulation of lipid metabolic process GO:0019216 118 0.028
negative regulation of growth GO:0045926 99 0.028
endocytosis GO:0006897 168 0.028
adaptive immune response GO:0002250 155 0.028
vascular process in circulatory system GO:0003018 62 0.027
killing of cells of other organism GO:0031640 13 0.027
protein kinase b signaling GO:0043491 74 0.027
Human
positive regulation of blood pressure GO:0045777 21 0.027
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.027
purine nucleoside metabolic process GO:0042278 241 0.027
negative regulation of homeostatic process GO:0032845 71 0.027
nucleobase containing small molecule metabolic process GO:0055086 352 0.027
alcohol catabolic process GO:0046164 16 0.027
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.026
ribonucleoside metabolic process GO:0009119 245 0.026
cellular glucose homeostasis GO:0001678 52 0.026
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.026
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.026
response to monosaccharide GO:0034284 67 0.026
negative regulation of endothelial cell migration GO:0010596 4 0.026
ovulation GO:0030728 15 0.026
aromatic compound catabolic process GO:0019439 286 0.026
steroid biosynthetic process GO:0006694 47 0.026
regulation of endocrine process GO:0044060 13 0.025
regulation of lipid transport GO:0032368 36 0.025
inflammatory response to antigenic stimulus GO:0002437 30 0.025
regulation of acute inflammatory response GO:0002673 27 0.025
c21 steroid hormone biosynthetic process GO:0006700 3 0.025
regulation of ion homeostasis GO:2000021 64 0.025
peptide hormone secretion GO:0030072 109 0.025
response to starvation GO:0042594 65 0.025
glycosyl compound metabolic process GO:1901657 246 0.025
Human
response to extracellular stimulus GO:0009991 127 0.024
response to acid chemical GO:0001101 111 0.024
Human
liver development GO:0001889 66 0.024
negative regulation of protein activation cascade GO:2000258 3 0.024
regulation of vasculature development GO:1901342 88 0.024
quinone metabolic process GO:1901661 7 0.024
Human
peptide transport GO:0015833 133 0.024
protein secretion GO:0009306 111 0.024
ribonucleoside triphosphate catabolic process GO:0009203 199 0.024
regulation of fatty acid biosynthetic process GO:0042304 12 0.024
negative regulation of apoptotic signaling pathway GO:2001234 104 0.024
positive regulation of protein phosphorylation GO:0001934 242 0.024
cellular biogenic amine metabolic process GO:0006576 28 0.024
monocarboxylic acid transport GO:0015718 44 0.023
nucleoside metabolic process GO:0009116 246 0.023
response to reactive oxygen species GO:0000302 56 0.023
ethanol metabolic process GO:0006067 3 0.023
response to alcohol GO:0097305 48 0.022
cellular response to glucose stimulus GO:0071333 45 0.022
purine containing compound metabolic process GO:0072521 311 0.022
extracellular structure organization GO:0043062 148 0.022
membrane lipid metabolic process GO:0006643 53 0.022
organ regeneration GO:0031100 2 0.022
cellular response to extracellular stimulus GO:0031668 81 0.022
positive regulation of transferase activity GO:0051347 167 0.021
isoprenoid catabolic process GO:0008300 2 0.021
regulation of steroid metabolic process GO:0019218 39 0.021
organic acid transport GO:0015849 101 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
cellular response to abiotic stimulus GO:0071214 56 0.021
ribonucleoside catabolic process GO:0042454 206 0.021
actin cytoskeleton organization GO:0030036 220 0.021
positive regulation of cytokine production GO:0001819 174 0.021
positive regulation of kinase activity GO:0033674 155 0.021
cellular response to external stimulus GO:0071496 88 0.021
positive regulation of protein kinase b signaling GO:0051897 32 0.021
Human
leukocyte differentiation GO:0002521 342 0.021
cellular metal ion homeostasis GO:0006875 151 0.020
cell type specific apoptotic process GO:0097285 268 0.020
polyol metabolic process GO:0019751 26 0.020
epithelial cell proliferation GO:0050673 174 0.020
coenzyme metabolic process GO:0006732 52 0.020
blood vessel morphogenesis GO:0048514 285 0.020
wound healing GO:0042060 157 0.020
inorganic ion transmembrane transport GO:0098660 234 0.020
nucleotide catabolic process GO:0009166 217 0.020
modification by symbiont of host morphology or physiology GO:0044003 4 0.020
regulation of anatomical structure size GO:0090066 178 0.020
regulation of cytokine biosynthetic process GO:0042035 59 0.020
positive regulation of fatty acid biosynthetic process GO:0045723 3 0.020
response to osmotic stress GO:0006970 21 0.020
c21 steroid hormone metabolic process GO:0008207 7 0.019
Human
cellular protein complex assembly GO:0043623 116 0.019
regulation of protein kinase b signaling GO:0051896 56 0.019
Human
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
alpha amino acid metabolic process GO:1901605 59 0.019
positive regulation of response to wounding GO:1903036 66 0.019
cellular divalent inorganic cation homeostasis GO:0072503 127 0.019
metal ion homeostasis GO:0055065 189 0.019
antigen processing and presentation GO:0019882 47 0.019
hemostasis GO:0007599 78 0.019
glucocorticoid metabolic process GO:0008211 9 0.019
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.019
heterocycle catabolic process GO:0046700 280 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.019
positive regulation of immune effector process GO:0002699 107 0.018
steroid hormone secretion GO:0035929 9 0.018
nucleoside catabolic process GO:0009164 206 0.018
lipid homeostasis GO:0055088 63 0.018
modification by host of symbiont morphology or physiology GO:0051851 12 0.018
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.018
sequestering of metal ion GO:0051238 19 0.018
positive regulation of defense response GO:0031349 124 0.018
disruption of cells of other organism GO:0044364 13 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
glycerophospholipid metabolic process GO:0006650 71 0.018
organophosphate catabolic process GO:0046434 232 0.018
nitric oxide biosynthetic process GO:0006809 25 0.018
glycosylation GO:0070085 62 0.017
nucleotide metabolic process GO:0009117 332 0.017
cytokine mediated signaling pathway GO:0019221 115 0.017
regulation of peptide secretion GO:0002791 77 0.017
regulation of ion transport GO:0043269 215 0.017
nik nf kappab signaling GO:0038061 14 0.017
regulation of feeding behavior GO:0060259 3 0.017
positive regulation of cellular carbohydrate metabolic process GO:0010676 29 0.017
positive regulation of homeostatic process GO:0032846 64 0.017
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.017
carbohydrate homeostasis GO:0033500 128 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
positive regulation of glucose metabolic process GO:0010907 21 0.017
organic acid catabolic process GO:0016054 51 0.017
regulation of carbohydrate metabolic process GO:0006109 75 0.017
receptor biosynthetic process GO:0032800 3 0.017
regulation of triglyceride metabolic process GO:0090207 17 0.017
protein n linked glycosylation GO:0006487 12 0.017
growth of symbiont in host GO:0044117 23 0.017
response to glucocorticoid GO:0051384 20 0.017
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.017
regulation of blood pressure GO:0008217 93 0.017
fatty acid biosynthetic process GO:0006633 41 0.017
leukocyte mediated cytotoxicity GO:0001909 62 0.017
phosphatidylinositol mediated signaling GO:0048015 41 0.017
cellular response to oxidative stress GO:0034599 76 0.017
epithelial tube morphogenesis GO:0060562 303 0.016
carboxylic acid transport GO:0046942 100 0.016
interaction with symbiont GO:0051702 14 0.016
myeloid leukocyte mediated immunity GO:0002444 42 0.016
acute inflammatory response to antigenic stimulus GO:0002438 12 0.016
interleukin 8 production GO:0032637 4 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
sequestering of calcium ion GO:0051208 18 0.016
transition metal ion transport GO:0000041 38 0.016
peptidyl serine phosphorylation GO:0018105 74 0.016
t helper 17 cell chemotaxis GO:0035705 1 0.016
endocrine hormone secretion GO:0060986 15 0.016
nitric oxide metabolic process GO:0046209 25 0.016

Akr1c6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.206
inherited metabolic disorder DOID:655 0 0.178
immune system disease DOID:2914 0 0.153
disease of anatomical entity DOID:7 0 0.153
blood coagulation disease DOID:1247 0 0.153
inherited blood coagulation disease DOID:2214 0 0.153
hematopoietic system disease DOID:74 0 0.153
lipid metabolism disorder DOID:3146 0 0.103
steroid inherited metabolic disorder DOID:1701 0 0.103
nervous system disease DOID:863 0 0.028
anemia DOID:2355 0 0.023
vascular disease DOID:178 0 0.022
cardiovascular system disease DOID:1287 0 0.022
normocytic anemia DOID:720 0 0.021
congenital adrenal hyperplasia DOID:0050811 0 0.019
plasma protein metabolism disease DOID:2345 0 0.018