Mus musculus

0 known processes

Larp4b

La ribonucleoprotein domain family, member 4B

(Aliases: A630096F19,MGC78318,D13Wsu64e,Larp5,AI256361)

Larp4b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heterocycle catabolic process GO:0046700 280 0.207
regulation of mapk cascade GO:0043408 248 0.192
regulation of hydrolase activity GO:0051336 246 0.154
positive regulation of cellular catabolic process GO:0031331 148 0.143
modification dependent macromolecule catabolic process GO:0043632 133 0.132
dna metabolic process GO:0006259 303 0.126
protein ubiquitination GO:0016567 171 0.117
modification dependent protein catabolic process GO:0019941 133 0.116
wnt signaling pathway GO:0016055 188 0.108
ubiquitin dependent protein catabolic process GO:0006511 129 0.097
actin cytoskeleton organization GO:0030036 220 0.096
endomembrane system organization GO:0010256 147 0.095
positive regulation of protein phosphorylation GO:0001934 242 0.087
regulation of organelle organization GO:0033043 289 0.086
regulation of cellular amine metabolic process GO:0033238 20 0.086
small gtpase mediated signal transduction GO:0007264 97 0.084
nucleoside metabolic process GO:0009116 246 0.084
cellular response to dna damage stimulus GO:0006974 207 0.082
purine nucleoside metabolic process GO:0042278 241 0.081
nucleotide catabolic process GO:0009166 217 0.081
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.079
negative regulation of intracellular signal transduction GO:1902532 167 0.079
regulation of cellular amino acid metabolic process GO:0006521 5 0.076
actin filament organization GO:0007015 113 0.074
purine ribonucleotide metabolic process GO:0009150 290 0.070
cellular protein catabolic process GO:0044257 155 0.068
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.068
glycosyl compound catabolic process GO:1901658 206 0.068
regulation of cellular component size GO:0032535 121 0.068
negative regulation of mapk cascade GO:0043409 65 0.067
regulation of cell cycle process GO:0010564 160 0.066
positive regulation of kinase activity GO:0033674 155 0.066
purine nucleotide metabolic process GO:0006163 302 0.066
ribose phosphate metabolic process GO:0019693 291 0.063
protein modification by small protein conjugation or removal GO:0070647 207 0.062
purine ribonucleoside catabolic process GO:0046130 205 0.062
dna repair GO:0006281 107 0.062
ras protein signal transduction GO:0007265 77 0.061
regulation of actin filament based process GO:0032970 99 0.061
regulation of proteolysis GO:0030162 164 0.060
regulation of kinase activity GO:0043549 249 0.060
cellular amino acid metabolic process GO:0006520 103 0.060
regulation of wnt signaling pathway GO:0030111 123 0.059
purine ribonucleoside metabolic process GO:0046128 241 0.059
regulation of ion transport GO:0043269 215 0.059
macromolecule catabolic process GO:0009057 281 0.055
positive regulation of cellular amine metabolic process GO:0033240 5 0.055
chromatin organization GO:0006325 206 0.055
compound eye development GO:0048749 1 0.054
purine containing compound metabolic process GO:0072521 311 0.054
negative regulation of phosphate metabolic process GO:0045936 184 0.053
cation transport GO:0006812 399 0.052
proteasomal protein catabolic process GO:0010498 98 0.052
negative regulation of cellular protein metabolic process GO:0032269 247 0.052
cellular nitrogen compound catabolic process GO:0044270 280 0.051
purine nucleoside catabolic process GO:0006152 205 0.051
meiotic cell cycle GO:0051321 122 0.050
nucleoside phosphate metabolic process GO:0006753 338 0.049
rho protein signal transduction GO:0007266 32 0.048
ribonucleoside catabolic process GO:0042454 206 0.047
amine metabolic process GO:0009308 45 0.047
purine nucleoside triphosphate catabolic process GO:0009146 203 0.047
positive regulation of proteolysis GO:0045862 85 0.047
i kappab kinase nf kappab signaling GO:0007249 85 0.047
regulation of anatomical structure size GO:0090066 178 0.046
purine nucleoside triphosphate metabolic process GO:0009144 226 0.046
protein polyubiquitination GO:0000209 33 0.046
membrane organization GO:0061024 245 0.045
regulation of cytoskeleton organization GO:0051493 122 0.045
ribonucleoside triphosphate metabolic process GO:0009199 220 0.045
regulation of nucleotide metabolic process GO:0006140 169 0.045
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.044
positive regulation of protein kinase activity GO:0045860 144 0.043
negative regulation of molecular function GO:0044092 258 0.043
nucleoside triphosphate catabolic process GO:0009143 205 0.043
gtp metabolic process GO:0046039 144 0.042
regulation of cellular catabolic process GO:0031329 242 0.041
meiotic cell cycle process GO:1903046 77 0.041
anion transport GO:0006820 177 0.040
carbohydrate derivative catabolic process GO:1901136 231 0.040
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.039
nucleoside phosphate catabolic process GO:1901292 222 0.039
macromolecule glycosylation GO:0043413 55 0.039
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.039
purine containing compound catabolic process GO:0072523 213 0.038
cellular macromolecule catabolic process GO:0044265 206 0.038
negative regulation of protein metabolic process GO:0051248 282 0.038
respiratory system development GO:0060541 190 0.038
regulation of proteasomal protein catabolic process GO:0061136 46 0.038
protein catabolic process GO:0030163 221 0.038
actin filament polymerization GO:0030041 44 0.038
posttranscriptional regulation of gene expression GO:0010608 155 0.037
Human
circadian regulation of gene expression GO:0032922 48 0.037
negative regulation of growth GO:0045926 99 0.037
endocytosis GO:0006897 168 0.036
male gamete generation GO:0048232 285 0.036
gland development GO:0048732 330 0.036
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
meiosis i GO:0007127 60 0.036
transmembrane transport GO:0055085 412 0.035
ribonucleotide catabolic process GO:0009261 208 0.035
regulation of cell cycle GO:0051726 281 0.035
positive regulation of protein modification process GO:0031401 299 0.035
oocyte construction GO:0007308 2 0.035
anion transmembrane transport GO:0098656 71 0.035
mitotic cell cycle GO:0000278 195 0.035
spermatogenesis GO:0007283 284 0.035
regulation of purine nucleotide metabolic process GO:1900542 169 0.035
mapk cascade GO:0000165 281 0.035
iron ion homeostasis GO:0055072 36 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.033
cell adhesion GO:0007155 329 0.033
negative regulation of phosphorus metabolic process GO:0010563 184 0.033
purine nucleotide catabolic process GO:0006195 211 0.033
regulation of protein catabolic process GO:0042176 108 0.033
regulation of protein kinase activity GO:0045859 232 0.033
germ cell development GO:0007281 185 0.032
cellular amine metabolic process GO:0044106 44 0.032
protein modification by small protein conjugation GO:0032446 187 0.032
cellular metal ion homeostasis GO:0006875 151 0.031
regulation of cellular response to stress GO:0080135 159 0.031
nucleoside catabolic process GO:0009164 206 0.031
negative regulation of cellular catabolic process GO:0031330 47 0.031
phagocytosis GO:0006909 66 0.030
positive regulation of hydrolase activity GO:0051345 148 0.030
regionalization GO:0003002 337 0.030
protein localization to organelle GO:0033365 185 0.030
glycosyl compound metabolic process GO:1901657 246 0.029
purine ribonucleotide catabolic process GO:0009154 208 0.029
ion transmembrane transport GO:0034220 361 0.029
chromatin modification GO:0016568 187 0.029
regulation of protein localization GO:0032880 231 0.028
cellular ketone metabolic process GO:0042180 84 0.028
regulation of actin cytoskeleton organization GO:0032956 84 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.028
aromatic compound catabolic process GO:0019439 286 0.028
digestive tract development GO:0048565 190 0.027
intracellular protein transport GO:0006886 204 0.027
regulation of cellular component biogenesis GO:0044087 181 0.027
cellular response to cytokine stimulus GO:0071345 189 0.027
metal ion homeostasis GO:0055065 189 0.027
localization within membrane GO:0051668 4 0.027
rhythmic process GO:0048511 174 0.027
negative regulation of phosphorylation GO:0042326 166 0.027
regulation of ion transmembrane transport GO:0034765 119 0.026
stem cell differentiation GO:0048863 268 0.026
actin polymerization or depolymerization GO:0008154 54 0.026
learning or memory GO:0007611 148 0.026
positive regulation of organelle organization GO:0010638 128 0.026
oocyte axis specification GO:0007309 2 0.026
regulation of actin filament length GO:0030832 45 0.026
lipid biosynthetic process GO:0008610 179 0.026
positive regulation of cytoskeleton organization GO:0051495 49 0.026
translation GO:0006412 93 0.025
Human
negative regulation of cell cycle process GO:0010948 69 0.025
organelle assembly GO:0070925 177 0.025
guanosine containing compound catabolic process GO:1901069 144 0.025
vesicle organization GO:0016050 60 0.025
regulation of gtp catabolic process GO:0033124 113 0.025
erk1 and erk2 cascade GO:0070371 77 0.025
negative regulation of protein phosphorylation GO:0001933 126 0.025
homeostasis of number of cells GO:0048872 210 0.025
peptidyl amino acid modification GO:0018193 336 0.025
regulation of mitotic cell cycle GO:0007346 126 0.024
regulation of cell projection organization GO:0031344 206 0.024
organic cyclic compound catabolic process GO:1901361 295 0.024
digestive system development GO:0055123 200 0.024
immune effector process GO:0002252 321 0.024
establishment or maintenance of cell polarity GO:0007163 86 0.024
spermatid development GO:0007286 108 0.024
chromosome segregation GO:0007059 48 0.024
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.024
regulation of purine nucleotide catabolic process GO:0033121 122 0.024
positive regulation of cellular protein catabolic process GO:1903364 34 0.024
glycoprotein metabolic process GO:0009100 116 0.023
apical constriction GO:0003383 4 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
ribonucleoside metabolic process GO:0009119 245 0.023
mitotic cell cycle process GO:1903047 159 0.023
n terminal protein amino acid modification GO:0031365 6 0.023
ribonucleotide metabolic process GO:0009259 291 0.023
positive regulation of protein catabolic process GO:0045732 60 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.023
respiratory tube development GO:0030323 167 0.023
organophosphate catabolic process GO:0046434 232 0.022
organelle localization GO:0051640 179 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
stress activated mapk cascade GO:0051403 80 0.022
regulation of protein stability GO:0031647 52 0.022
regulation of cellular protein catabolic process GO:1903362 61 0.022
canonical wnt signaling pathway GO:0060070 130 0.022
nucleotide metabolic process GO:0009117 332 0.022
protein acylation GO:0043543 64 0.022
protein polymerization GO:0051258 57 0.022
lipid localization GO:0010876 126 0.021
inorganic anion transport GO:0015698 43 0.021
cellular transition metal ion homeostasis GO:0046916 32 0.021
positive regulation of wnt signaling pathway GO:0030177 45 0.020
cellular homeostasis GO:0019725 240 0.020
regulation of endocytosis GO:0030100 69 0.020
cellular chemical homeostasis GO:0055082 215 0.020
spermatid differentiation GO:0048515 115 0.020
lipid transport GO:0006869 98 0.019
positive regulation of nucleotide metabolic process GO:0045981 114 0.019
regulation of ras gtpase activity GO:0032318 88 0.019
lung development GO:0030324 164 0.019
cognition GO:0050890 149 0.019
cytokine production GO:0001816 319 0.019
negative regulation of hydrolase activity GO:0051346 71 0.019
maintenance of location GO:0051235 89 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.019
regulation of mitotic cell cycle phase transition GO:1901990 73 0.019
olfactory learning GO:0008355 2 0.019
regulation of ras protein signal transduction GO:0046578 114 0.019
dephosphorylation GO:0016311 129 0.019
inorganic ion transmembrane transport GO:0098660 234 0.019
organelle fission GO:0048285 170 0.019
dna damage checkpoint GO:0000077 26 0.019
jak stat cascade GO:0007259 42 0.018
regulation of cell migration GO:0030334 219 0.018
cellular ion homeostasis GO:0006873 165 0.018
protein glycosylation GO:0006486 55 0.018
cellular lipid metabolic process GO:0044255 323 0.018
regulation of actin nucleation GO:0051125 4 0.018
regulation of cellular ketone metabolic process GO:0010565 66 0.018
circadian rhythm GO:0007623 114 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.018
regulation of nucleotide catabolic process GO:0030811 122 0.018
pole plasm assembly GO:0007315 2 0.017
nuclear transport GO:0051169 139 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
dendrite development GO:0016358 115 0.017
blood vessel morphogenesis GO:0048514 285 0.017
negative regulation of cell cycle GO:0045786 123 0.017
cell cycle checkpoint GO:0000075 47 0.017
jnk cascade GO:0007254 72 0.017
cation homeostasis GO:0055080 212 0.016
regulation of body fluid levels GO:0050878 162 0.016
regulation of actin filament polymerization GO:0030833 38 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
regulation of clathrin mediated endocytosis GO:2000369 4 0.016
histone modification GO:0016570 159 0.016
regulation of defense response GO:0031347 233 0.016
exocytosis GO:0006887 121 0.016
leukocyte mediated immunity GO:0002443 174 0.016
nitrogen compound transport GO:0071705 271 0.016
carbon catabolite regulation of transcription GO:0045990 4 0.016
positive regulation of transferase activity GO:0051347 167 0.015
innate immune response GO:0045087 157 0.015
carbohydrate metabolic process GO:0005975 230 0.015
regulation of transferase activity GO:0051338 263 0.015
rac protein signal transduction GO:0016601 13 0.015
protein localization to nucleus GO:0034504 121 0.015
regulation of calcium ion transport GO:0051924 69 0.015
transition metal ion homeostasis GO:0055076 54 0.015
fat cell differentiation GO:0045444 160 0.015
neural tube development GO:0021915 160 0.015
positive regulation of cell motility GO:2000147 116 0.015
sequestering of metal ion GO:0051238 19 0.015
single organism cell adhesion GO:0098602 156 0.015
cellular iron ion homeostasis GO:0006879 16 0.015
carbon catabolite activation of transcription GO:0045991 4 0.015
methylation GO:0032259 134 0.015
regulation of response to wounding GO:1903034 189 0.015
sulfur compound metabolic process GO:0006790 100 0.015
neuromuscular process GO:0050905 99 0.015
regulation of t cell activation GO:0050863 170 0.015
kidney development GO:0001822 213 0.015
ameboidal type cell migration GO:0001667 128 0.014
asymmetric stem cell division GO:0098722 3 0.014
covalent chromatin modification GO:0016569 163 0.014
smoothened signaling pathway GO:0007224 105 0.014
interleukin 6 production GO:0032635 58 0.014
inter male aggressive behavior GO:0002121 3 0.014
acylglycerol metabolic process GO:0006639 55 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
gtp catabolic process GO:0006184 143 0.014
erbb signaling pathway GO:0038127 32 0.014
amide transport GO:0042886 138 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
protein processing GO:0016485 163 0.014
regulation of neuron projection development GO:0010975 169 0.014
organic hydroxy compound transport GO:0015850 93 0.014
inorganic anion transmembrane transport GO:0098661 29 0.014
negative regulation of protein modification process GO:0031400 163 0.014
chloride transmembrane transport GO:1902476 24 0.014
tube closure GO:0060606 91 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
positive regulation of gtpase activity GO:0043547 85 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
regulation of fat cell differentiation GO:0045598 81 0.013
regulation of innate immune response GO:0045088 91 0.013
single fertilization GO:0007338 82 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
regulation of protein processing GO:0070613 96 0.013
cellular response to extracellular stimulus GO:0031668 81 0.013
positive regulation of cell cycle GO:0045787 92 0.013
regulation of transmembrane transport GO:0034762 128 0.013
cellular protein complex assembly GO:0043623 116 0.013
dna integrity checkpoint GO:0031570 28 0.013
maternal determination of anterior posterior axis embryo GO:0008358 2 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
t cell differentiation GO:0030217 174 0.013
cell substrate adhesion GO:0031589 130 0.013
neutral lipid metabolic process GO:0006638 57 0.013
digestive tract morphogenesis GO:0048546 147 0.013
protein localization to cell junction GO:1902414 3 0.013
myeloid cell homeostasis GO:0002262 114 0.013
digestion GO:0007586 40 0.013
female gamete generation GO:0007292 74 0.013
glycoprotein biosynthetic process GO:0009101 89 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
limb development GO:0060173 166 0.013
regulation of endopeptidase activity GO:0052548 89 0.013
intracellular lipid transport GO:0032365 3 0.013
protein autophosphorylation GO:0046777 61 0.013
liver development GO:0001889 66 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
regulation of metal ion transport GO:0010959 106 0.012
renal system development GO:0072001 225 0.012
regulation of rho protein signal transduction GO:0035023 71 0.012
myeloid cell differentiation GO:0030099 233 0.012
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.012
epithelial tube formation GO:0072175 130 0.012
non canonical wnt signaling pathway GO:0035567 33 0.012
notch signaling pathway GO:0007219 71 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.012
establishment of organelle localization GO:0051656 122 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
regulation of actin polymerization or depolymerization GO:0008064 45 0.012
nucleoside monophosphate catabolic process GO:0009125 59 0.012
chemotaxis GO:0006935 247 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
b cell activation GO:0042113 161 0.012
intracellular mrna localization GO:0008298 4 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
t cell activation GO:0042110 289 0.012
regulation of stress activated mapk cascade GO:0032872 69 0.012
glycerolipid biosynthetic process GO:0045017 50 0.012
plasma membrane organization GO:0007009 90 0.012
mitotic cytokinesis GO:0000281 4 0.011
negative regulation of sterol transport GO:0032372 4 0.011
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.011
regulation of organ morphogenesis GO:2000027 144 0.011
oogenesis GO:0048477 56 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
negative regulation of nucleotide catabolic process GO:0030812 9 0.011
regulation of inflammatory response GO:0050727 147 0.011
regulation of histone modification GO:0031056 56 0.011
lung cell differentiation GO:0060479 30 0.011
g1 s transition of mitotic cell cycle GO:0000082 57 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
positive regulation of transcription by galactose GO:0000411 1 0.011
cation transmembrane transport GO:0098655 266 0.011
regulation of jnk cascade GO:0046328 62 0.011
glucose homeostasis GO:0042593 128 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
response to growth factor GO:0070848 198 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.011
positive regulation of macroautophagy GO:0016239 3 0.011
mesodermal cell migration GO:0008078 4 0.011
divalent metal ion transport GO:0070838 172 0.011
fertilization GO:0009566 127 0.011
lipid homeostasis GO:0055088 63 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.011
aminoglycan metabolic process GO:0006022 34 0.011
negative regulation of dna replication GO:0008156 4 0.011
negative regulation of synapse assembly GO:0051964 3 0.011
cell division GO:0051301 120 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
regulation of neuron death GO:1901214 134 0.011
meiotic nuclear division GO:0007126 115 0.011
blastocyst development GO:0001824 80 0.011
cell cycle g1 s phase transition GO:0044843 57 0.011
habituation GO:0046959 3 0.011
actin mediated cell contraction GO:0070252 15 0.011
regulation of cell size GO:0008361 72 0.011
regulation of cell cycle phase transition GO:1901987 77 0.011
single organism nuclear import GO:1902593 95 0.010
cytokine mediated signaling pathway GO:0019221 115 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
cellular amide metabolic process GO:0043603 58 0.010
negative regulation of triglyceride metabolic process GO:0090209 4 0.010
regulation of peptidase activity GO:0052547 96 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
regulation of map kinase activity GO:0043405 120 0.010
regulation of protein complex assembly GO:0043254 83 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010
neural tube closure GO:0001843 90 0.010
intracellular receptor signaling pathway GO:0030522 74 0.010
negative regulation of kinase activity GO:0033673 81 0.010
nucleoside triphosphate metabolic process GO:0009141 230 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
response to extracellular stimulus GO:0009991 127 0.010
nucleus organization GO:0006997 45 0.010

Larp4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.055
musculoskeletal system disease DOID:17 0 0.055
myopathy DOID:423 0 0.019
congenital muscular dystrophy DOID:0050557 0 0.019
muscular disease DOID:0080000 0 0.019
muscular dystrophy DOID:9884 0 0.019
muscle tissue disease DOID:66 0 0.019
bone development disease DOID:0080006 0 0.015
bone disease DOID:0080001 0 0.015
connective tissue disease DOID:65 0 0.015
nervous system disease DOID:863 0 0.014
neuropathy DOID:870 0 0.014
osteochondrodysplasia DOID:2256 0 0.010