Mus musculus

125 known processes

Paf1

Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)

(Aliases: 5730511K23Rik,MGC102062,FLJ11123,AA675045)

Paf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna processing GO:0006397 63 0.124
mrna metabolic process GO:0016071 84 0.098
cell adhesion GO:0007155 329 0.085
mitotic cell cycle GO:0000278 195 0.078
cellular response to dna damage stimulus GO:0006974 207 0.070
positive regulation of dna templated transcription elongation GO:0032786 2 0.067
covalent chromatin modification GO:0016569 163 0.063
cellular ketone metabolic process GO:0042180 84 0.055
blastocyst growth GO:0001832 23 0.055
regulation of cellular ketone metabolic process GO:0010565 66 0.053
cellular amino acid metabolic process GO:0006520 103 0.052
positive regulation of cellular amine metabolic process GO:0033240 5 0.051
amine metabolic process GO:0009308 45 0.046
rna processing GO:0006396 105 0.046
organelle fission GO:0048285 170 0.045
apoptotic signaling pathway GO:0097190 306 0.044
regulation of cellular amine metabolic process GO:0033238 20 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
regulation of cellular amino acid metabolic process GO:0006521 5 0.042
protein refolding GO:0042026 1 0.042
positive regulation of protein modification process GO:0031401 299 0.039
nuclear division GO:0000280 158 0.039
blastocyst development GO:0001824 80 0.039
regulation of organelle organization GO:0033043 289 0.038
regulation of mrna metabolic process GO:1903311 43 0.038
cellular amine metabolic process GO:0044106 44 0.037
organelle assembly GO:0070925 177 0.035
stem cell maintenance GO:0019827 130 0.034
cytoplasmic transport GO:0016482 234 0.034
peptidyl amino acid modification GO:0018193 336 0.033
stem cell differentiation GO:0048863 268 0.032
dna repair GO:0006281 107 0.031
protein localization to organelle GO:0033365 185 0.030
purine nucleotide metabolic process GO:0006163 302 0.030
regulation of mrna processing GO:0050684 41 0.029
nuclear transport GO:0051169 139 0.029
regulation of cellular response to stress GO:0080135 159 0.029
dna metabolic process GO:0006259 303 0.028
negative regulation of immune system process GO:0002683 209 0.028
regulation of transferase activity GO:0051338 263 0.027
histone h3 k4 methylation GO:0051568 23 0.027
positive regulation of protein phosphorylation GO:0001934 242 0.026
membrane organization GO:0061024 245 0.025
regulation of cell cycle process GO:0010564 160 0.025
regulation of histone h3 k4 methylation GO:0051569 12 0.025
regulation of cell cycle GO:0051726 281 0.024
mrna splicing via spliceosome GO:0000398 43 0.024
positive regulation of cell death GO:0010942 224 0.024
cation transport GO:0006812 399 0.024
gland development GO:0048732 330 0.024
response to organonitrogen compound GO:0010243 246 0.024
endocytosis GO:0006897 168 0.023
mitotic cell cycle process GO:1903047 159 0.023
nitrogen compound transport GO:0071705 271 0.023
negative regulation of molecular function GO:0044092 258 0.023
cellular macromolecule catabolic process GO:0044265 206 0.023
rna splicing via transesterification reactions GO:0000375 43 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
nucleobase containing small molecule metabolic process GO:0055086 352 0.022
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.022
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.022
histone modification GO:0016570 159 0.022
regulation of neuron differentiation GO:0045664 281 0.022
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.022
positive regulation of organelle organization GO:0010638 128 0.022
chromatin modification GO:0016568 187 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.021
cell growth GO:0016049 130 0.021
nucleotide metabolic process GO:0009117 332 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
rna splicing GO:0008380 54 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
aromatic compound catabolic process GO:0019439 286 0.020
glycosyl compound metabolic process GO:1901657 246 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
immune effector process GO:0002252 321 0.019
intrinsic apoptotic signaling pathway GO:0097193 132 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
lipid biosynthetic process GO:0008610 179 0.019
positive regulation of programmed cell death GO:0043068 218 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
cellular response to cytokine stimulus GO:0071345 189 0.019
endomembrane system organization GO:0010256 147 0.018
regulation of cell growth GO:0001558 91 0.018
maintenance of location GO:0051235 89 0.018
chromatin organization GO:0006325 206 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
protein ubiquitination GO:0016567 171 0.018
regulation of histone methylation GO:0031060 30 0.018
organelle localization GO:0051640 179 0.018
ribonucleoprotein complex subunit organization GO:0071826 28 0.018
cell type specific apoptotic process GO:0097285 268 0.018
regulation of protein localization GO:0032880 231 0.018
regulation of chromatin organization GO:1902275 57 0.018
germ cell development GO:0007281 185 0.017
transmembrane transport GO:0055085 412 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
protein localization to nucleus GO:0034504 121 0.017
positive regulation of kinase activity GO:0033674 155 0.017
nucleoside metabolic process GO:0009116 246 0.017
purine containing compound metabolic process GO:0072521 311 0.017
cation transmembrane transport GO:0098655 266 0.017
regulation of chromosome organization GO:0033044 83 0.017
cell fate commitment GO:0045165 210 0.017
mapk cascade GO:0000165 281 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
negative regulation of dna replication GO:0008156 4 0.016
regulation of protein kinase activity GO:0045859 232 0.016
cellular lipid metabolic process GO:0044255 323 0.016
regulation of chromatin modification GO:1903308 57 0.016
stem cell development GO:0048864 219 0.016
digestive system development GO:0055123 200 0.016
regulation of kinase activity GO:0043549 249 0.016
regulation of cell projection organization GO:0031344 206 0.016
oocyte axis specification GO:0007309 2 0.016
heterocycle catabolic process GO:0046700 280 0.016
positive regulation of protein kinase activity GO:0045860 144 0.016
regulation of rna splicing GO:0043484 37 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.016
meiotic nuclear division GO:0007126 115 0.016
internal protein amino acid acetylation GO:0006475 42 0.016
protein methylation GO:0006479 81 0.016
ribose phosphate metabolic process GO:0019693 291 0.015
muscle tissue development GO:0060537 308 0.015
dna templated transcription termination GO:0006353 4 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
hormone metabolic process GO:0042445 86 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
cytokine production GO:0001816 319 0.015
striated muscle tissue development GO:0014706 293 0.015
nucleotide catabolic process GO:0009166 217 0.015
regulation of cell activation GO:0050865 289 0.015
inclusion body assembly GO:0070841 3 0.015
inner cell mass cell proliferation GO:0001833 15 0.015
protein catabolic process GO:0030163 221 0.015
pole plasm assembly GO:0007315 2 0.015
gonad development GO:0008406 141 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
nucleoside monophosphate metabolic process GO:0009123 85 0.014
regulation of protein complex assembly GO:0043254 83 0.014
adult behavior GO:0030534 135 0.014
regulation of response to dna damage stimulus GO:2001020 34 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
asymmetric stem cell division GO:0098722 3 0.014
regulation of hormone levels GO:0010817 211 0.014
lymphocyte differentiation GO:0030098 242 0.014
organophosphate catabolic process GO:0046434 232 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
intracellular protein transport GO:0006886 204 0.014
intracellular mrna localization GO:0008298 4 0.014
protein alkylation GO:0008213 81 0.014
regulation of neuron projection development GO:0010975 169 0.014
regulation of cell shape GO:0008360 39 0.014
response to radiation GO:0009314 165 0.014
response to peptide hormone GO:0043434 127 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
snorna metabolic process GO:0016074 1 0.014
regulation of cell cycle phase transition GO:1901987 77 0.014
regulation of histone modification GO:0031056 56 0.014
oocyte anterior posterior axis specification GO:0007314 2 0.014
response to temperature stimulus GO:0009266 55 0.014
meiotic cell cycle GO:0051321 122 0.013
regulation of membrane potential GO:0042391 192 0.013
regulation of cell division GO:0051302 76 0.013
transmission of nerve impulse GO:0019226 76 0.013
receptor mediated endocytosis GO:0006898 51 0.013
activation of immune response GO:0002253 138 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
macromolecule catabolic process GO:0009057 281 0.013
actin cytoskeleton organization GO:0030036 220 0.013
gastrulation GO:0007369 116 0.013
muscle cell differentiation GO:0042692 261 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
protein localization to membrane GO:0072657 108 0.013
positive regulation of defense response GO:0031349 124 0.013
neuronal action potential GO:0019228 54 0.013
methylation GO:0032259 134 0.013
leukocyte mediated immunity GO:0002443 174 0.013
innate immune response GO:0045087 157 0.013
transcription from rna polymerase i promoter GO:0006360 13 0.013
response to lipopolysaccharide GO:0032496 128 0.013
regulation of defense response GO:0031347 233 0.013
ras protein signal transduction GO:0007265 77 0.013
action potential GO:0001508 78 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
positive regulation of transferase activity GO:0051347 167 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
glycosyl compound catabolic process GO:1901658 206 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
histone lysine methylation GO:0034968 50 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
cellular chemical homeostasis GO:0055082 215 0.012
male gamete generation GO:0048232 285 0.012
regulation of cytokine production GO:0001817 266 0.012
synapse organization GO:0050808 125 0.012
positive regulation of mapk cascade GO:0043410 170 0.012
nucleoside catabolic process GO:0009164 206 0.012
male meiosis i GO:0007141 16 0.012
microtubule based process GO:0007017 236 0.012
myeloid cell differentiation GO:0030099 233 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
digestive tract development GO:0048565 190 0.012
negative regulation of cell cycle process GO:0010948 69 0.012
compound eye development GO:0048749 1 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
retrograde transport endosome to golgi GO:0042147 2 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
spermatogenesis GO:0007283 284 0.012
negative regulation of protein modification process GO:0031400 163 0.012
regulation of mrna splicing via spliceosome GO:0048024 32 0.012
forebrain development GO:0030900 302 0.012
positive regulation of histone methylation GO:0031062 16 0.012
atp metabolic process GO:0046034 75 0.012
neuron apoptotic process GO:0051402 142 0.012
response to peptide GO:1901652 136 0.012
immune response regulating signaling pathway GO:0002764 125 0.012
lipid localization GO:0010876 126 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
response to heat GO:0009408 27 0.012
negative regulation of cell cycle GO:0045786 123 0.011
regulation of multi organism process GO:0043900 111 0.011
positive regulation of chromosome organization GO:2001252 33 0.011
camera type eye development GO:0043010 266 0.011
response to insulin GO:0032868 100 0.011
regulation of binding GO:0051098 111 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
protein acylation GO:0043543 64 0.011
small molecule biosynthetic process GO:0044283 132 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
wnt signaling pathway GO:0016055 188 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
positive regulation of nervous system development GO:0051962 221 0.011
leukocyte differentiation GO:0002521 342 0.011
blood vessel morphogenesis GO:0048514 285 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
multicellular organismal signaling GO:0035637 91 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
axonogenesis GO:0007409 274 0.011
response to acid chemical GO:0001101 111 0.011
peptidyl lysine modification GO:0018205 77 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
regulation of cell motility GO:2000145 236 0.011
fertilization GO:0009566 127 0.011
regulation of intracellular transport GO:0032386 159 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
inter male aggressive behavior GO:0002121 3 0.011
divalent inorganic cation transport GO:0072511 178 0.011
leukocyte activation involved in immune response GO:0002366 126 0.011
positive regulation of chromatin modification GO:1903310 28 0.011
positive regulation of histone modification GO:0031058 28 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
positive regulation of histone h3 k4 methylation GO:0051571 5 0.011
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.011
cell activation involved in immune response GO:0002263 126 0.011
purine containing compound catabolic process GO:0072523 213 0.011
regulation of chromatin silencing GO:0031935 2 0.011
positive regulation of homeostatic process GO:0032846 64 0.011
regulation of hydrolase activity GO:0051336 246 0.011
response to light stimulus GO:0009416 135 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
macromolecule methylation GO:0043414 120 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.010
interspecies interaction between organisms GO:0044419 83 0.010
peptidyl tyrosine modification GO:0018212 145 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.010
regulation of anatomical structure size GO:0090066 178 0.010
regulation of dna damage checkpoint GO:2000001 3 0.010
response to organic cyclic compound GO:0014070 198 0.010
carbohydrate derivative catabolic process GO:1901136 231 0.010
purine nucleoside monophosphate metabolic process GO:0009126 81 0.010
nuclear import GO:0051170 95 0.010
maternal determination of anterior posterior axis embryo GO:0008358 2 0.010
positive regulation of apoptotic signaling pathway GO:2001235 95 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
regulation of cytoplasmic transport GO:1903649 112 0.010
cellular response to molecule of bacterial origin GO:0071219 83 0.010
regulation of neuron death GO:1901214 134 0.010
histone methylation GO:0016571 71 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
plasma membrane organization GO:0007009 90 0.010
carbohydrate metabolic process GO:0005975 230 0.010
angiogenesis GO:0001525 201 0.010
regulation of cell migration GO:0030334 219 0.010
regulation of response to wounding GO:1903034 189 0.010
regulation of cellular component size GO:0032535 121 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
inflammatory response GO:0006954 244 0.010
cellular homeostasis GO:0019725 240 0.010

Paf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
musculoskeletal system disease DOID:17 0 0.014
immune system disease DOID:2914 0 0.013
central nervous system disease DOID:331 0 0.011
neurodegenerative disease DOID:1289 0 0.011
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010
hematopoietic system disease DOID:74 0 0.010