Mus musculus

191 known processes

Irf3

interferon regulatory factor 3

(Aliases: IRF-3,MGC91046,C920001K05Rik)

Irf3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.139
regulation of cellular ketone metabolic process GO:0010565 66 0.068
amine metabolic process GO:0009308 45 0.055
regulation of lymphocyte activation GO:0051249 240 0.052
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
cellular amino acid metabolic process GO:0006520 103 0.046
dna metabolic process GO:0006259 303 0.046
regulation of cellular amino acid metabolic process GO:0006521 5 0.043
immune effector process GO:0002252 321 0.042
regulation of hydrolase activity GO:0051336 246 0.042
regulation of mapk cascade GO:0043408 248 0.041
cellular nitrogen compound catabolic process GO:0044270 280 0.040
modification dependent macromolecule catabolic process GO:0043632 133 0.040
cellular amine metabolic process GO:0044106 44 0.040
regulation of cell activation GO:0050865 289 0.038
Mouse
negative regulation of immune system process GO:0002683 209 0.038
organic cyclic compound catabolic process GO:1901361 295 0.036
regulation of cellular amine metabolic process GO:0033238 20 0.036
aromatic compound catabolic process GO:0019439 286 0.036
positive regulation of hydrolase activity GO:0051345 148 0.034
mapk cascade GO:0000165 281 0.034
transmembrane transport GO:0055085 412 0.033
cellular ion homeostasis GO:0006873 165 0.033
protein localization to nucleus GO:0034504 121 0.032
cytokine production GO:0001816 319 0.031
cation homeostasis GO:0055080 212 0.031
cell type specific apoptotic process GO:0097285 268 0.031
cellular chemical homeostasis GO:0055082 215 0.031
cation transport GO:0006812 399 0.030
regulation of secretion by cell GO:1903530 249 0.030
regulation of membrane potential GO:0042391 192 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
glycosyl compound metabolic process GO:1901657 246 0.028
regulation of transferase activity GO:0051338 263 0.028
innate immune response GO:0045087 157 0.027
immune response regulating signaling pathway GO:0002764 125 0.027
Mouse
cell adhesion GO:0007155 329 0.026
myeloid cell differentiation GO:0030099 233 0.026
Mouse
skin development GO:0043588 220 0.026
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.026
regulation of defense response GO:0031347 233 0.025
metal ion homeostasis GO:0055065 189 0.024
protein localization to organelle GO:0033365 185 0.024
ras protein signal transduction GO:0007265 77 0.024
purine ribonucleoside metabolic process GO:0046128 241 0.023
glycosyl compound catabolic process GO:1901658 206 0.023
protein maturation GO:0051604 176 0.023
macromolecule catabolic process GO:0009057 281 0.023
peptidyl amino acid modification GO:0018193 336 0.023
Mouse
negative regulation of defense response GO:0031348 77 0.023
leukocyte differentiation GO:0002521 342 0.023
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.022
neuron death GO:0070997 154 0.022
nucleoside catabolic process GO:0009164 206 0.022
regulation of cell cycle GO:0051726 281 0.022
negative regulation of cell development GO:0010721 169 0.022
regulation of kinase activity GO:0043549 249 0.022
organophosphate catabolic process GO:0046434 232 0.022
heterocycle catabolic process GO:0046700 280 0.022
ribose phosphate metabolic process GO:0019693 291 0.022
ribonucleotide metabolic process GO:0009259 291 0.021
purine nucleoside metabolic process GO:0042278 241 0.021
cellular lipid metabolic process GO:0044255 323 0.021
purine containing compound metabolic process GO:0072521 311 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
positive regulation of mapk cascade GO:0043410 170 0.020
cellular metal ion homeostasis GO:0006875 151 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
compound eye development GO:0048749 1 0.020
divalent inorganic cation transport GO:0072511 178 0.020
apoptotic signaling pathway GO:0097190 306 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.019
nucleotide catabolic process GO:0009166 217 0.019
ribonucleoside metabolic process GO:0009119 245 0.019
regulation of reactive oxygen species metabolic process GO:2000377 40 0.019
regulation of binding GO:0051098 111 0.019
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.019
proteasomal protein catabolic process GO:0010498 98 0.019
cellular divalent inorganic cation homeostasis GO:0072503 127 0.019
cytoplasmic transport GO:0016482 234 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
regulation of cellular response to stress GO:0080135 159 0.019
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.018
positive regulation of protein modification process GO:0031401 299 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.018
striated muscle tissue development GO:0014706 293 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
inflammatory response GO:0006954 244 0.018
positive regulation of cell death GO:0010942 224 0.018
extrinsic apoptotic signaling pathway GO:0097191 126 0.018
nitrogen compound transport GO:0071705 271 0.018
purine nucleotide catabolic process GO:0006195 211 0.018
maintenance of location GO:0051235 89 0.017
defense response to other organism GO:0098542 197 0.017
cellular homeostasis GO:0019725 240 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
blood vessel morphogenesis GO:0048514 285 0.017
organonitrogen compound catabolic process GO:1901565 264 0.017
positive regulation of nucleoside metabolic process GO:0045979 91 0.017
regulation of body fluid levels GO:0050878 162 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
glycoprotein biosynthetic process GO:0009101 89 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
activation of immune response GO:0002253 138 0.017
Mouse
chromatin organization GO:0006325 206 0.017
Mouse
muscle tissue development GO:0060537 308 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
protein import GO:0017038 101 0.016
histone modification GO:0016570 159 0.016
Mouse
regulation of cytokine production GO:0001817 266 0.016
response to radiation GO:0009314 165 0.016
stem cell differentiation GO:0048863 268 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
protein targeting GO:0006605 143 0.016
positive regulation of transferase activity GO:0051347 167 0.016
gland development GO:0048732 330 0.016
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
regulation of organelle organization GO:0033043 289 0.016
lymphocyte differentiation GO:0030098 242 0.016
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.016
Mouse
purine nucleoside catabolic process GO:0006152 205 0.015
actin filament organization GO:0007015 113 0.015
nuclear import GO:0051170 95 0.015
intracellular protein transport GO:0006886 204 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
regulation of homeostatic process GO:0032844 182 0.015
forebrain development GO:0030900 302 0.015
glucose homeostasis GO:0042593 128 0.015
ion transmembrane transport GO:0034220 361 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
regulation of myeloid cell differentiation GO:0045637 96 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
immune response activating signal transduction GO:0002757 116 0.015
Mouse
t cell activation GO:0042110 289 0.015
Mouse
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.015
regionalization GO:0003002 337 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
lymphocyte mediated immunity GO:0002449 139 0.015
Mouse
action potential GO:0001508 78 0.015
negative regulation of molecular function GO:0044092 258 0.014
response to light stimulus GO:0009416 135 0.014
regulation of protein localization GO:0032880 231 0.014
muscle cell differentiation GO:0042692 261 0.014
protein autophosphorylation GO:0046777 61 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.014
digestive system development GO:0055123 200 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
positive regulation of actin nucleation GO:0051127 3 0.014
cation transmembrane transport GO:0098655 266 0.014
peptide transport GO:0015833 133 0.014
mitotic cell cycle process GO:1903047 159 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
protein localization to peroxisome GO:0072662 4 0.013
positive regulation of protein transport GO:0051222 93 0.013
regulation of cysteine type endopeptidase activity GO:2000116 65 0.013
glycerolipid metabolic process GO:0046486 122 0.013
regulation of ral gtpase activity GO:0032315 4 0.013
nucleoside metabolic process GO:0009116 246 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
regulation of map kinase activity GO:0043405 120 0.013
skeletal muscle organ development GO:0060538 163 0.013
viral gene expression GO:0019080 3 0.013
membrane organization GO:0061024 245 0.013
neuron apoptotic process GO:0051402 142 0.013
rna processing GO:0006396 105 0.013
nuclear transport GO:0051169 139 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
regulation of feeding behavior GO:0060259 3 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
positive regulation of cell activation GO:0050867 158 0.013
negative regulation of immune effector process GO:0002698 55 0.012
calcium ion homeostasis GO:0055074 127 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
protein processing GO:0016485 163 0.012
sterol homeostasis GO:0055092 45 0.012
glycoprotein metabolic process GO:0009100 116 0.012
telencephalon development GO:0021537 186 0.012
lipid homeostasis GO:0055088 63 0.012
cellular response to lipid GO:0071396 145 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
camera type eye development GO:0043010 266 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
digestive tract development GO:0048565 190 0.012
cilium morphogenesis GO:0060271 102 0.012
i kappab kinase nf kappab signaling GO:0007249 85 0.012
nucleotide metabolic process GO:0009117 332 0.012
wnt signaling pathway GO:0016055 188 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
spermatogenesis GO:0007283 284 0.012
actin cytoskeleton organization GO:0030036 220 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
activation of mapk activity GO:0000187 59 0.012
response to lipopolysaccharide GO:0032496 128 0.012
multicellular organism growth GO:0035264 161 0.012
mitochondrion organization GO:0007005 134 0.012
carbohydrate homeostasis GO:0033500 128 0.012
gtp metabolic process GO:0046039 144 0.011
lateral inhibition GO:0046331 1 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
Mouse
cellular protein catabolic process GO:0044257 155 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
sequestering of metal ion GO:0051238 19 0.011
adult behavior GO:0030534 135 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
Mouse
mitotic cytokinesis GO:0000281 4 0.011
protein ubiquitination GO:0016567 171 0.011
defense response to bacterium GO:0042742 119 0.011
Mouse
asymmetric stem cell division GO:0098722 3 0.011
macromolecule glycosylation GO:0043413 55 0.011
regulation of t cell activation GO:0050863 170 0.011
Mouse
multicellular organismal homeostasis GO:0048871 164 0.011
interleukin 8 production GO:0032637 4 0.011
methylation GO:0032259 134 0.011
Mouse
regulation of secretion GO:0051046 274 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
regulation of neuron projection development GO:0010975 169 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
response to acid chemical GO:0001101 111 0.011
regulation of adaptive immune response GO:0002819 90 0.011
regulation of inflammatory response GO:0050727 147 0.011
positive regulation of cell development GO:0010720 237 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
positive regulation of interleukin 8 production GO:0032757 2 0.011
protein glycosylation GO:0006486 55 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
negative regulation of multi organism process GO:0043901 68 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
homeostasis of number of cells GO:0048872 210 0.011
t cell proliferation GO:0042098 120 0.011
Mouse
mrna metabolic process GO:0016071 84 0.011
protein polymerization GO:0051258 57 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
asymmetric neuroblast division GO:0055059 1 0.011
regulation of peptide transport GO:0090087 91 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.010
heart morphogenesis GO:0003007 178 0.010
regulation of actin nucleation GO:0051125 4 0.010
transcription from rna polymerase iii promoter GO:0006383 3 0.010
macromolecule methylation GO:0043414 120 0.010
Mouse
amide transport GO:0042886 138 0.010
mechanoreceptor differentiation GO:0042490 67 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.010
transmission of nerve impulse GO:0019226 76 0.010
lipid biosynthetic process GO:0008610 179 0.010
multicellular organismal signaling GO:0035637 91 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
microtubule based process GO:0007017 236 0.010
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.010
viral transcription GO:0019083 3 0.010
cognition GO:0050890 149 0.010
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.010
regulation of ras gtpase activity GO:0032318 88 0.010
fatty acid metabolic process GO:0006631 121 0.010
skeletal system development GO:0001501 356 0.010
gliogenesis GO:0042063 141 0.010

Irf3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
immune system disease DOID:2914 0 0.015
central nervous system disease DOID:331 0 0.011