Mus musculus

94 known processes

Irf6

interferon regulatory factor 6

(Aliases: E230028I05Rik,AI876454,mirf6)

Irf6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
keratinocyte development GO:0003334 10 0.936
morphogenesis of embryonic epithelium GO:0016331 159 0.723
skin development GO:0043588 220 0.695
epithelial cell proliferation GO:0050673 174 0.628
multicellular organismal water homeostasis GO:0050891 23 0.612
regulation of epithelial cell proliferation GO:0050678 141 0.569
keratinocyte differentiation GO:0030216 48 0.567
negative regulation of epithelial cell proliferation GO:0050680 64 0.561
keratinocyte proliferation GO:0043616 21 0.558
regulation of water loss via skin GO:0033561 16 0.553
establishment of skin barrier GO:0061436 14 0.526
epithelial cell development GO:0002064 159 0.414
regulation of epidermal cell differentiation GO:0045604 21 0.402
regulation of body fluid levels GO:0050878 162 0.390
cell adhesion GO:0007155 329 0.350
water homeostasis GO:0030104 27 0.349
negative regulation of keratinocyte proliferation GO:0010839 7 0.333
negative regulation of cell proliferation GO:0008285 296 0.305
cell junction organization GO:0034330 77 0.301
stem cell proliferation GO:0072089 117 0.294
morphogenesis of a branching structure GO:0001763 203 0.261
regulation of keratinocyte proliferation GO:0010837 15 0.247
epidermis development GO:0008544 187 0.236
limb development GO:0060173 166 0.232
epithelial tube morphogenesis GO:0060562 303 0.222
forebrain development GO:0030900 302 0.218
regionalization GO:0003002 337 0.214
regulation of epidermis development GO:0045682 33 0.213
morphogenesis of a branching epithelium GO:0061138 193 0.187
regulation of establishment of protein localization GO:0070201 181 0.186
positive regulation of programmed cell death GO:0043068 218 0.185
digestive tract development GO:0048565 190 0.183
regulation of epidermal cell division GO:0010482 3 0.177
regulation of proteolysis GO:0030162 164 0.173
regulation of cellular component biogenesis GO:0044087 181 0.173
Mouse
regulation of stem cell proliferation GO:0072091 78 0.172
negative regulation of protein metabolic process GO:0051248 282 0.164
Mouse
gland development GO:0048732 330 0.164
t cell differentiation in thymus GO:0033077 77 0.161
urogenital system development GO:0001655 261 0.161
single organism cell adhesion GO:0098602 156 0.161
cell cell junction organization GO:0045216 72 0.160
embryonic epithelial tube formation GO:0001838 130 0.153
negative regulation of transferase activity GO:0051348 85 0.149
cell division GO:0051301 120 0.147
renal system development GO:0072001 225 0.147
positive regulation of epidermal cell differentiation GO:0045606 6 0.147
amine metabolic process GO:0009308 45 0.146
gastrulation GO:0007369 116 0.146
spermatogenesis GO:0007283 284 0.144
leukocyte proliferation GO:0070661 172 0.143
Mouse
establishment or maintenance of cell polarity GO:0007163 86 0.141
salivary gland development GO:0007431 37 0.141
cell junction assembly GO:0034329 52 0.138
sensory organ morphogenesis GO:0090596 242 0.137
cellular response to cytokine stimulus GO:0071345 189 0.137
Mouse
inclusion body assembly GO:0070841 3 0.136
muscle tissue development GO:0060537 308 0.135
protein modification by small protein conjugation or removal GO:0070647 207 0.134
thermosensory behavior GO:0040040 1 0.131
mapk cascade GO:0000165 281 0.129
oocyte axis specification GO:0007309 2 0.128
digestive tract morphogenesis GO:0048546 147 0.127
regulation of nucleocytoplasmic transport GO:0046822 73 0.127
epidermal cell division GO:0010481 3 0.126
t cell activation involved in immune response GO:0002286 43 0.125
Mouse
regulation of transferase activity GO:0051338 263 0.124
neural precursor cell proliferation GO:0061351 121 0.124
lymphocyte activation involved in immune response GO:0002285 93 0.122
Mouse
regulation of peptidase activity GO:0052547 96 0.119
regulation of cysteine type endopeptidase activity GO:2000116 65 0.119
lymphocyte differentiation GO:0030098 242 0.119
Mouse
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.118
leukocyte differentiation GO:0002521 342 0.118
Mouse
regulation of intracellular transport GO:0032386 159 0.117
positive regulation of protein export from nucleus GO:0046827 4 0.117
regulation of protein localization GO:0032880 231 0.115
t cell differentiation GO:0030217 174 0.115
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.112
ear development GO:0043583 200 0.111
regulation of t cell differentiation GO:0045580 83 0.111
Mouse
axonogenesis GO:0007409 274 0.110
lymphocyte proliferation GO:0046651 164 0.106
Mouse
positive regulation of cell activation GO:0050867 158 0.105
positive regulation of epidermis development GO:0045684 13 0.104
circulatory system process GO:0003013 197 0.103
hair follicle development GO:0001942 85 0.102
cellular glucan metabolic process GO:0006073 32 0.099
cellular ketone metabolic process GO:0042180 84 0.098
homeostasis of number of cells GO:0048872 210 0.098
ventricular cardiac muscle cell action potential GO:0086005 4 0.097
small molecule biosynthetic process GO:0044283 132 0.097
regulation of actin filament based process GO:0032970 99 0.096
membrane organization GO:0061024 245 0.096
endocytosis GO:0006897 168 0.095
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.095
apoptotic mitochondrial changes GO:0008637 48 0.095
protein targeting GO:0006605 143 0.095
regulation of protein transport GO:0051223 163 0.093
odontogenesis of dentin containing tooth GO:0042475 66 0.092
regulation of neuron differentiation GO:0045664 281 0.091
multicellular organismal signaling GO:0035637 91 0.090
regulation of lymphocyte activation GO:0051249 240 0.089
Mouse
regulation of intracellular protein transport GO:0033157 82 0.089
appendage development GO:0048736 166 0.087
regulation of endopeptidase activity GO:0052548 89 0.086
single organismal cell cell adhesion GO:0016337 131 0.083
renal tubule development GO:0061326 87 0.083
action potential GO:0001508 78 0.082
segmentation GO:0035282 93 0.082
cell growth GO:0016049 130 0.082
cellular amine metabolic process GO:0044106 44 0.082
cell fate commitment GO:0045165 210 0.082
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.081
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.081
regulation of wnt signaling pathway GO:0030111 123 0.081
cardiac muscle tissue development GO:0048738 130 0.080
protein processing GO:0016485 163 0.080
regulation of leukocyte differentiation GO:1902105 159 0.079
Mouse
regulation of cytoplasmic transport GO:1903649 112 0.079
epithelial cell morphogenesis GO:0003382 41 0.078
regulation of protein maturation GO:1903317 96 0.078
morphogenesis of a polarized epithelium GO:0001738 37 0.078
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.078
intracellular protein transport GO:0006886 204 0.077
positive regulation of protein transport GO:0051222 93 0.077
dephosphorylation GO:0016311 129 0.076
nucleocytoplasmic transport GO:0006913 139 0.076
apoptotic signaling pathway GO:0097190 306 0.075
negative regulation of phosphorus metabolic process GO:0010563 184 0.074
organic hydroxy compound metabolic process GO:1901615 203 0.074
regulation of hydrolase activity GO:0051336 246 0.074
organelle assembly GO:0070925 177 0.073
positive regulation of apoptotic signaling pathway GO:2001235 95 0.073
cellular amino acid metabolic process GO:0006520 103 0.073
ossification GO:0001503 216 0.073
telencephalon development GO:0021537 186 0.072
activation of immune response GO:0002253 138 0.072
Mouse
alpha beta t cell differentiation GO:0046632 69 0.072
Mouse
transmembrane transport GO:0055085 412 0.071
positive regulation of cell death GO:0010942 224 0.071
positive regulation of hydrolase activity GO:0051345 148 0.070
formation of radial glial scaffolds GO:0021943 4 0.070
blood circulation GO:0008015 195 0.070
dna metabolic process GO:0006259 303 0.070
oxidation reduction process GO:0055114 342 0.070
neural tube development GO:0021915 160 0.069
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.069
positive regulation of leukocyte differentiation GO:1902107 86 0.069
nuclear transport GO:0051169 139 0.069
cytoplasmic transport GO:0016482 234 0.068
negative regulation of stem cell proliferation GO:2000647 12 0.068
forebrain radial glial cell differentiation GO:0021861 4 0.068
regulation of hormone levels GO:0010817 211 0.068
pallium development GO:0021543 120 0.067
cardiac chamber morphogenesis GO:0003206 93 0.067
regulation of neuron projection development GO:0010975 169 0.067
inorganic cation transmembrane transport GO:0098662 207 0.066
hepaticobiliary system development GO:0061008 67 0.065
negative regulation of cell cycle GO:0045786 123 0.065
Human
regulation of protein serine threonine kinase activity GO:0071900 157 0.065
dna replication GO:0006260 52 0.065
positive regulation of proteolysis GO:0045862 85 0.065
positive regulation of apoptotic process GO:0043065 217 0.064
protein modification by small protein conjugation GO:0032446 187 0.064
posttranscriptional regulation of gene expression GO:0010608 155 0.064
sensory perception GO:0007600 245 0.064
t cell activation GO:0042110 289 0.064
Mouse
regulation of protein processing GO:0070613 96 0.063
regulation of cell projection organization GO:0031344 206 0.063
regulation of organelle organization GO:0033043 289 0.063
nephron development GO:0072006 109 0.063
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.063
fat cell differentiation GO:0045444 160 0.063
skeletal system development GO:0001501 356 0.062
Zebrafish
cardiac chamber development GO:0003205 108 0.062
regulation of protein kinase activity GO:0045859 232 0.061
activation of cysteine type endopeptidase activity GO:0097202 27 0.061
embryonic skeletal system development GO:0048706 120 0.061
Zebrafish
regulation of organ morphogenesis GO:2000027 144 0.061
protein maturation GO:0051604 176 0.061
neuron migration GO:0001764 122 0.060
mitochondrion organization GO:0007005 134 0.060
asymmetric neuroblast division GO:0055059 1 0.060
cardiac muscle cell contraction GO:0086003 7 0.059
lipid biosynthetic process GO:0008610 179 0.059
ear morphogenesis GO:0042471 118 0.059
protein localization to membrane GO:0072657 108 0.057
regulation of anatomical structure size GO:0090066 178 0.057
establishment of organelle localization GO:0051656 122 0.057
myeloid cell differentiation GO:0030099 233 0.057
Mouse
regulation of kinase activity GO:0043549 249 0.057
odontogenesis GO:0042476 78 0.057
regulation of cell cycle GO:0051726 281 0.057
Human
germ cell development GO:0007281 185 0.056
regulation of cell adhesion GO:0030155 154 0.056
innate immune response GO:0045087 157 0.056
Mouse
actin cytoskeleton organization GO:0030036 220 0.056
establishment of planar polarity GO:0001736 28 0.055
anatomical structure homeostasis GO:0060249 145 0.055
positive regulation of intracellular transport GO:0032388 70 0.054
bmp signaling pathway GO:0030509 93 0.054
cell cell adhesion GO:0098609 41 0.054
embryonic organ morphogenesis GO:0048562 276 0.053
Zebrafish
negative regulation of proteolysis GO:0045861 74 0.053
morphogenesis of an epithelial sheet GO:0002011 27 0.052
neural tube formation GO:0001841 108 0.052
mitotic cell cycle GO:0000278 195 0.052
regulation of fat cell differentiation GO:0045598 81 0.052
negative regulation of ubiquitin protein transferase activity GO:0051444 3 0.052
regulation of ras protein signal transduction GO:0046578 114 0.052
kidney development GO:0001822 213 0.052
cell cell junction assembly GO:0007043 27 0.051
embryonic limb morphogenesis GO:0030326 126 0.051
respiratory system development GO:0060541 190 0.051
reactive oxygen species metabolic process GO:0072593 84 0.051
regulation of cytoskeleton organization GO:0051493 122 0.051
negative regulation of protein modification process GO:0031400 163 0.050
leukocyte activation involved in immune response GO:0002366 126 0.050
Mouse
male gamete generation GO:0048232 285 0.050
striated muscle contraction GO:0006941 45 0.050
negative regulation of immune system process GO:0002683 209 0.049
Mouse
carbohydrate metabolic process GO:0005975 230 0.049
chemotaxis GO:0006935 247 0.049
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.049
positive regulation of cell development GO:0010720 237 0.049
heart contraction GO:0060047 93 0.048
apical junction assembly GO:0043297 15 0.048
regulation of membrane potential GO:0042391 192 0.048
macromolecule catabolic process GO:0009057 281 0.048
cell maturation GO:0048469 127 0.048
tissue remodeling GO:0048771 102 0.048
regulation of erk1 and erk2 cascade GO:0070372 71 0.048
organelle localization GO:0051640 179 0.048
negative regulation of molecular function GO:0044092 258 0.048
inflammatory response GO:0006954 244 0.048
exocrine system development GO:0035272 45 0.048
positive regulation of nervous system development GO:0051962 221 0.047
cerebral cortex development GO:0021987 86 0.047
regulation of cellular ketone metabolic process GO:0010565 66 0.047
neuron projection guidance GO:0097485 141 0.046
inner ear morphogenesis GO:0042472 101 0.046
fertilization GO:0009566 127 0.046
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.046
positive regulation of endopeptidase activity GO:0010950 43 0.045
response to acid chemical GO:0001101 111 0.045
dendrite development GO:0016358 115 0.045
protein localization to organelle GO:0033365 185 0.045
developmental programmed cell death GO:0010623 41 0.045
negative regulation of leukocyte differentiation GO:1902106 51 0.045
Mouse
negative regulation of ligase activity GO:0051352 3 0.045
embryonic placenta development GO:0001892 98 0.045
positive regulation of mapk cascade GO:0043410 170 0.045
stem cell development GO:0048864 219 0.045
cell type specific apoptotic process GO:0097285 268 0.044
regulation of neural precursor cell proliferation GO:2000177 70 0.044
cytokine mediated signaling pathway GO:0019221 115 0.044
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.044
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.044
microtubule based process GO:0007017 236 0.044
respiratory tube development GO:0030323 167 0.044
muscle contraction GO:0006936 101 0.043
organelle fission GO:0048285 170 0.043
regulation of transmembrane transport GO:0034762 128 0.043
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.043
cardiac ventricle development GO:0003231 83 0.043
neuroblast proliferation GO:0007405 49 0.043
cellular response to gamma radiation GO:0071480 4 0.042
positive regulation of lymphocyte differentiation GO:0045621 61 0.042
heart morphogenesis GO:0003007 178 0.042
cardiac septum morphogenesis GO:0060411 46 0.042
primary neural tube formation GO:0014020 95 0.042
camera type eye development GO:0043010 266 0.042
oocyte construction GO:0007308 2 0.041
erk1 and erk2 cascade GO:0070371 77 0.041
response to organonitrogen compound GO:0010243 246 0.041
stem cell maintenance GO:0019827 130 0.041
multicellular organismal homeostasis GO:0048871 164 0.041
negative regulation of mitotic cell cycle GO:0045930 58 0.041
liver development GO:0001889 66 0.041
negative regulation of organelle organization GO:0010639 90 0.040
mitochondrion degradation GO:0000422 3 0.040
blood vessel morphogenesis GO:0048514 285 0.040
regulation of action potential GO:0098900 4 0.040
cell activation involved in immune response GO:0002263 126 0.040
Mouse
neural tube closure GO:0001843 90 0.040
axon guidance GO:0007411 141 0.040
cellular carbohydrate metabolic process GO:0044262 119 0.040
positive regulation of intracellular protein transport GO:0090316 42 0.039
cellular response to starvation GO:0009267 57 0.039
cellular response to growth factor stimulus GO:0071363 197 0.039
negative regulation of cellular component organization GO:0051129 194 0.039
establishment of protein localization to organelle GO:0072594 118 0.038
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.038
Mouse
negative regulation of dna replication GO:0008156 4 0.038
extrinsic apoptotic signaling pathway GO:0097191 126 0.038
cell fate specification GO:0001708 72 0.038
regulation of mitotic cell cycle GO:0007346 126 0.038
response to organic cyclic compound GO:0014070 198 0.038
Mouse
stem cell differentiation GO:0048863 268 0.038
regulation of lymphocyte differentiation GO:0045619 107 0.037
Mouse
muscle tissue morphogenesis GO:0060415 53 0.037
epidermis morphogenesis GO:0048730 33 0.037
embryonic appendage morphogenesis GO:0035113 126 0.037
regulation of actin cytoskeleton organization GO:0032956 84 0.037
response to lipopolysaccharide GO:0032496 128 0.037
Mouse
hindbrain development GO:0030902 128 0.037
kidney epithelium development GO:0072073 121 0.037
small gtpase mediated signal transduction GO:0007264 97 0.037
molting cycle GO:0042303 90 0.037
regulation of reactive oxygen species metabolic process GO:2000377 40 0.036
positive regulation of cell motility GO:2000147 116 0.036
positive regulation of cellular amine metabolic process GO:0033240 5 0.036
positive regulation of leukocyte proliferation GO:0070665 73 0.036
cell migration involved in gastrulation GO:0042074 13 0.036
regulation of cell division GO:0051302 76 0.036
thrombin receptor signaling pathway GO:0070493 2 0.036
nuclear division GO:0000280 158 0.036
cellular lipid metabolic process GO:0044255 323 0.036
regulation of defense response GO:0031347 233 0.036
Mouse
endomembrane system organization GO:0010256 147 0.035
regulation of osteoblast differentiation GO:0045667 67 0.035
mesoderm development GO:0007498 100 0.035
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.035
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.035
regulation of ligase activity GO:0051340 10 0.035
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.035
protein ubiquitination GO:0016567 171 0.035
cofactor metabolic process GO:0051186 80 0.034
cell junction maintenance GO:0034331 4 0.034
desmosome organization GO:0002934 5 0.034
asymmetric stem cell division GO:0098722 3 0.034
organism emergence from protective structure GO:0071684 4 0.034
retina development in camera type eye GO:0060041 119 0.034
positive regulation of macroautophagy GO:0016239 3 0.034
skin morphogenesis GO:0043589 38 0.034
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.034
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051439 1 0.033
tight junction assembly GO:0070830 9 0.033
nephron tubule development GO:0072080 84 0.033
t cell selection GO:0045058 34 0.033
Mouse
hippocampus development GO:0021766 52 0.033
regulation of t cell activation GO:0050863 170 0.033
Mouse
cellular homeostasis GO:0019725 240 0.033
leukocyte chemotaxis GO:0030595 69 0.033
wound healing GO:0042060 157 0.033
muscle cell differentiation GO:0042692 261 0.033
cardiac ventricle morphogenesis GO:0003208 50 0.033
female genitalia morphogenesis GO:0048807 3 0.032
positive regulation of protein modification process GO:0031401 299 0.032
regulation of apoptotic signaling pathway GO:2001233 197 0.032
establishment of spindle localization GO:0051293 19 0.032
negative regulation of myeloid cell differentiation GO:0045638 38 0.032
axis elongation involved in somitogenesis GO:0090245 4 0.032
developmental growth involved in morphogenesis GO:0060560 138 0.032
chromatin organization GO:0006325 206 0.032
Mouse
notch signaling pathway GO:0007219 71 0.032
central nervous system neuron differentiation GO:0021953 162 0.031
gliogenesis GO:0042063 141 0.031
positive regulation of t cell activation GO:0050870 101 0.031
somite development GO:0061053 81 0.031
skeletal system morphogenesis GO:0048705 203 0.031
Zebrafish
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.031
tissue homeostasis GO:0001894 115 0.031
regulation of myeloid cell differentiation GO:0045637 96 0.031
regulation of system process GO:0044057 200 0.031
hatching GO:0035188 4 0.031
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.031
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.031
mammary gland epithelium development GO:0061180 65 0.031
negative regulation of apoptotic signaling pathway GO:2001234 104 0.030
regulation of mitotic cell cycle phase transition GO:1901990 73 0.030
somite specification GO:0001757 4 0.030
regulation of protein targeting GO:1903533 61 0.030
leukocyte migration GO:0050900 124 0.030
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.030
endothelium development GO:0003158 45 0.030
formation of primary germ layer GO:0001704 77 0.030
tube closure GO:0060606 91 0.030
cerebrospinal fluid secretion GO:0033326 4 0.030
chemokine production GO:0032602 34 0.030
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.030
positive regulation of podosome assembly GO:0071803 3 0.030
regulation of secretion GO:0051046 274 0.030
epithelial tube formation GO:0072175 130 0.030
cellular response to x ray GO:0071481 2 0.030
necroptotic process GO:0070266 21 0.030
regulation of protein import into nucleus GO:0042306 52 0.030
t cell proliferation GO:0042098 120 0.030
Mouse
regulation of heart contraction GO:0008016 77 0.030
negative regulation of kinase activity GO:0033673 81 0.030
positive regulation of ras protein signal transduction GO:0046579 13 0.030
thymic t cell selection GO:0045061 22 0.030
palate development GO:0060021 76 0.030
cerebellum development GO:0021549 77 0.030
jnk cascade GO:0007254 72 0.029
developmental maturation GO:0021700 193 0.029
nuclear import GO:0051170 95 0.029
monocarboxylic acid biosynthetic process GO:0072330 61 0.029
cellular modified amino acid metabolic process GO:0006575 63 0.029
cation transmembrane transport GO:0098655 266 0.029
alpha amino acid metabolic process GO:1901605 59 0.029
rho protein signal transduction GO:0007266 32 0.029
response to molecule of bacterial origin GO:0002237 143 0.029
Mouse
single organism nuclear import GO:1902593 95 0.029
cellular chemical homeostasis GO:0055082 215 0.029
muscle cell proliferation GO:0033002 52 0.029
release of cytochrome c from mitochondria GO:0001836 23 0.029
cardiac muscle tissue morphogenesis GO:0055008 44 0.029
mitotic g1 dna damage checkpoint GO:0031571 4 0.029
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.029
immune effector process GO:0002252 321 0.029
Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.029
muscle system process GO:0003012 141 0.029
negative regulation of phosphorylation GO:0042326 166 0.029
regulation of mapk cascade GO:0043408 248 0.029
lipid localization GO:0010876 126 0.028
t helper cell differentiation GO:0042093 28 0.028
Mouse
protein catabolic process GO:0030163 221 0.028
negative regulation of protein maturation GO:1903318 79 0.028
leukocyte apoptotic process GO:0071887 71 0.028
synapse assembly GO:0007416 56 0.028
negative regulation of peptidase activity GO:0010466 46 0.028
signal transduction involved in dna damage checkpoint GO:0072422 3 0.028
regulation of cellular amine metabolic process GO:0033238 20 0.028
placenta development GO:0001890 140 0.028
regulation of protein localization to nucleus GO:1900180 60 0.028
energy derivation by oxidation of organic compounds GO:0015980 77 0.028
protein localization to nucleus GO:0034504 121 0.028
neuronal action potential GO:0019228 54 0.028
regulation of interleukin 6 production GO:0032675 55 0.028
negative regulation of ossification GO:0030279 49 0.027
cardiac right atrium morphogenesis GO:0003213 3 0.027
transmission of nerve impulse GO:0019226 76 0.027
regulation of cell activation GO:0050865 289 0.027
Mouse
peptide transport GO:0015833 133 0.027
regulation of leukocyte proliferation GO:0070663 121 0.027
Mouse
negative regulation of protein processing GO:0010955 79 0.027
covalent chromatin modification GO:0016569 163 0.027
Mouse
peptide hormone secretion GO:0030072 109 0.027
endodermal cell fate specification GO:0001714 4 0.027
regulation of canonical wnt signaling pathway GO:0060828 82 0.027
i kappab kinase nf kappab signaling GO:0007249 85 0.027
intrinsic apoptotic signaling pathway GO:0097193 132 0.027
synapse organization GO:0050808 125 0.027
limbic system development GO:0021761 72 0.027
calcium independent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016338 4 0.027
positive regulation of immature t cell proliferation GO:0033091 4 0.027
actin filament based movement GO:0030048 23 0.026
membrane lipid biosynthetic process GO:0046467 32 0.026
ras protein signal transduction GO:0007265 77 0.026
positive regulation of secretion GO:0051047 130 0.026
protein import GO:0017038 101 0.026
positive regulation of cell adhesion GO:0045785 80 0.026
cellular response to nutrient levels GO:0031669 64 0.026
neuron apoptotic process GO:0051402 142 0.026
learning or memory GO:0007611 148 0.026
histone modification GO:0016570 159 0.026
Mouse
establishment of tissue polarity GO:0007164 28 0.026
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 3 0.026
negative regulation of intracellular signal transduction GO:1902532 167 0.026
lateral inhibition GO:0046331 1 0.026
organic acid biosynthetic process GO:0016053 86 0.026
ventral spinal cord development GO:0021517 48 0.026
regulation of blood circulation GO:1903522 93 0.026
detection of abiotic stimulus GO:0009582 60 0.026
striated muscle tissue development GO:0014706 293 0.026
salivary gland morphogenesis GO:0007435 33 0.026
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.026
cognition GO:0050890 149 0.026
regulation of cell motility GO:2000145 236 0.026
positive regulation of t cell differentiation GO:0045582 52 0.025
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.025
canonical wnt signaling pathway involved in neural crest cell differentiation GO:0044335 1 0.025
negative regulation of jun kinase activity GO:0043508 9 0.025
hair follicle morphogenesis GO:0031069 29 0.025
microglia development GO:0014005 2 0.025
mesenchymal cell differentiation GO:0048762 107 0.025

Irf6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.186
muscular disease DOID:0080000 0 0.186
heart disease DOID:114 0 0.186
cardiomyopathy DOID:0050700 0 0.186
disease of anatomical entity DOID:7 0 0.186
intrinsic cardiomyopathy DOID:0060036 0 0.186
cardiovascular system disease DOID:1287 0 0.186
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 0 0.186
musculoskeletal system disease DOID:17 0 0.186
muscle tissue disease DOID:66 0 0.186
nervous system disease DOID:863 0 0.062
connective tissue disease DOID:65 0 0.037
bone disease DOID:0080001 0 0.035
thoracic cancer DOID:5093 0 0.032
cancer DOID:162 0 0.032
disease of cellular proliferation DOID:14566 0 0.032
organ system cancer DOID:0050686 0 0.032