Mus musculus

259 known processes

Htr2b

5-hydroxytryptamine (serotonin) receptor 2B

(Aliases: AV377389,AJ012488,5-HT2B)

Htr2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
inflammatory response GO:0006954 244 0.627
regulation of inflammatory response GO:0050727 147 0.328
amine metabolic process GO:0009308 45 0.319
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.227
Human Mouse
lipid biosynthetic process GO:0008610 179 0.219
Human
oxidation reduction process GO:0055114 342 0.200
Human
t cell activation GO:0042110 289 0.187
positive regulation of cellular amine metabolic process GO:0033240 5 0.183
negative regulation of cell proliferation GO:0008285 296 0.182
regulation of ion transport GO:0043269 215 0.174
Mouse
apoptotic signaling pathway GO:0097190 306 0.171
regulation of establishment of protein localization GO:0070201 181 0.161
angiogenesis GO:0001525 201 0.157
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.153
Human Mouse
regulation of secretion GO:0051046 274 0.148
positive regulation of protein phosphorylation GO:0001934 242 0.147
Human Mouse
regulation of defense response GO:0031347 233 0.143
organophosphate biosynthetic process GO:0090407 122 0.140
Human Mouse
regulation of mapk cascade GO:0043408 248 0.134
Human
regulation of blood pressure GO:0008217 93 0.129
Mouse
circulatory system process GO:0003013 197 0.127
Human Mouse
positive regulation of apoptotic process GO:0043065 217 0.126
detection of stimulus GO:0051606 84 0.125
response to organonitrogen compound GO:0010243 246 0.123
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.122
response to molecule of bacterial origin GO:0002237 143 0.121
negative regulation of vasculature development GO:1901343 26 0.120
regulation of response to wounding GO:1903034 189 0.118
positive regulation of secretion GO:0051047 130 0.118
blood vessel morphogenesis GO:0048514 285 0.115
Mouse
small molecule biosynthetic process GO:0044283 132 0.115
positive regulation of secretion by cell GO:1903532 114 0.113
regulation of protein transport GO:0051223 163 0.112
cellular amine metabolic process GO:0044106 44 0.111
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.110
extracellular matrix organization GO:0030198 147 0.109
protein secretion GO:0009306 111 0.107
reactive oxygen species biosynthetic process GO:1903409 8 0.106
ribose phosphate metabolic process GO:0019693 291 0.105
regulation of nucleotide metabolic process GO:0006140 169 0.104
positive regulation of protein modification process GO:0031401 299 0.102
Human Mouse
cellular ketone metabolic process GO:0042180 84 0.099
cellular lipid metabolic process GO:0044255 323 0.097
Human
leukocyte proliferation GO:0070661 172 0.097
intrinsic apoptotic signaling pathway GO:0097193 132 0.095
ribonucleotide metabolic process GO:0009259 291 0.095
regulation of cell motility GO:2000145 236 0.094
Mouse
regulation of systemic arterial blood pressure GO:0003073 61 0.093
Mouse
nucleotide biosynthetic process GO:0009165 78 0.093
Human Mouse
regulation of proteolysis GO:0030162 164 0.092
regulation of secretion by cell GO:1903530 249 0.091
nucleotide metabolic process GO:0009117 332 0.090
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.086
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.086
Human
multicellular organismal homeostasis GO:0048871 164 0.085
Mouse
ribonucleotide biosynthetic process GO:0009260 59 0.081
Human Mouse
blood circulation GO:0008015 195 0.079
Human Mouse
endocrine process GO:0050886 39 0.079
positive regulation of programmed cell death GO:0043068 218 0.077
response to lipopolysaccharide GO:0032496 128 0.077
regulation of cellular response to stress GO:0080135 159 0.075
defense response to gram positive bacterium GO:0050830 50 0.075
defense response to bacterium GO:0042742 119 0.073
regulation of hormone levels GO:0010817 211 0.073
Mouse
tissue remodeling GO:0048771 102 0.073
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 95 0.072
regulation of cellular ketone metabolic process GO:0010565 66 0.072
immune effector process GO:0002252 321 0.070
nucleoside phosphate biosynthetic process GO:1901293 79 0.069
Human Mouse
regulation of cell activation GO:0050865 289 0.069
regulation of cellular amine metabolic process GO:0033238 20 0.068
Mouse
bone development GO:0060348 120 0.068
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.068
metal ion homeostasis GO:0055065 189 0.067
Human Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.067
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.067
positive regulation of inflammatory response GO:0050729 47 0.066
cellular chemical homeostasis GO:0055082 215 0.066
Human Mouse
purine nucleotide metabolic process GO:0006163 302 0.065
cyclic nucleotide metabolic process GO:0009187 59 0.065
Human Mouse
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.064
Human Mouse
regulation of system process GO:0044057 200 0.064
Mouse
purine containing compound metabolic process GO:0072521 311 0.063
cytosolic calcium ion homeostasis GO:0051480 70 0.062
Human Mouse
nucleoside metabolic process GO:0009116 246 0.062
bone remodeling GO:0046849 53 0.062
Mouse
positive regulation of kinase activity GO:0033674 155 0.060
Human Mouse
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.059
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.059
regulation of protein secretion GO:0050708 82 0.058
ribose phosphate biosynthetic process GO:0046390 59 0.058
Human Mouse
leukocyte mediated immunity GO:0002443 174 0.057
positive regulation of protein kinase activity GO:0045860 144 0.057
Human
purine ribonucleotide biosynthetic process GO:0009152 59 0.056
Human Mouse
cellular carbohydrate metabolic process GO:0044262 119 0.056
Mouse
tissue homeostasis GO:0001894 115 0.056
Mouse
positive regulation of mapk cascade GO:0043410 170 0.055
Human
regulation of vasculature development GO:1901342 88 0.055
regulation of protein kinase activity GO:0045859 232 0.055
Human
b cell activation GO:0042113 161 0.055
cognition GO:0050890 149 0.055
Mouse
regulation of camp metabolic process GO:0030814 30 0.054
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.054
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.053
Human
cellular metal ion homeostasis GO:0006875 151 0.053
Human Mouse
lipid transport GO:0006869 98 0.051
norepinephrine transport GO:0015874 2 0.051
leukocyte differentiation GO:0002521 342 0.051
antibacterial peptide biosynthetic process GO:0002780 2 0.050
alcohol metabolic process GO:0006066 116 0.050
cellular response to biotic stimulus GO:0071216 92 0.050
organic hydroxy compound metabolic process GO:1901615 203 0.050
Mouse
response to acid chemical GO:0001101 111 0.050
regulation of muscle system process GO:0090257 80 0.049
Mouse
dna metabolic process GO:0006259 303 0.049
reactive oxygen species metabolic process GO:0072593 84 0.049
production of molecular mediator of immune response GO:0002440 103 0.048
acute inflammatory response GO:0002526 41 0.048
cellular response to oxidative stress GO:0034599 76 0.048
smooth muscle contraction GO:0006939 44 0.048
Human Mouse
regulation of acute inflammatory response GO:0002673 27 0.048
negative regulation of hydrolase activity GO:0051346 71 0.048
b cell proliferation GO:0042100 53 0.048
leukocyte activation involved in immune response GO:0002366 126 0.048
cyclic purine nucleotide metabolic process GO:0052652 43 0.048
Human Mouse
regulation of protein localization GO:0032880 231 0.048
regulation of hydrolase activity GO:0051336 246 0.047
anatomical structure homeostasis GO:0060249 145 0.047
Mouse
camp metabolic process GO:0046058 40 0.046
Mouse
muscle system process GO:0003012 141 0.046
fat cell differentiation GO:0045444 160 0.045
Mouse
norepinephrine secretion GO:0048243 2 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.045
positive regulation of cell death GO:0010942 224 0.044
cellular response to hormone stimulus GO:0032870 150 0.044
regulation of cell migration GO:0030334 219 0.044
Mouse
regulation of kinase activity GO:0043549 249 0.043
Human Mouse
ribonucleoside metabolic process GO:0009119 245 0.043
regulation of norepinephrine secretion GO:0014061 2 0.043
regulation of angiogenesis GO:0045765 81 0.043
anion transport GO:0006820 177 0.042
glycoprotein biosynthetic process GO:0009101 89 0.042
extracellular structure organization GO:0043062 148 0.042
cellular response to lipid GO:0071396 145 0.041
positive regulation of protein transport GO:0051222 93 0.041
multicellular organismal signaling GO:0035637 91 0.041
Mouse
regulation of muscle tissue development GO:1901861 97 0.041
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.041
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.041
Mouse
positive regulation of innate immune response GO:0045089 80 0.041
protein maturation GO:0051604 176 0.040
urogenital system development GO:0001655 261 0.040
cellular ion homeostasis GO:0006873 165 0.040
Human Mouse
renal system process GO:0003014 48 0.040
cytokine mediated signaling pathway GO:0019221 115 0.040
regulation of membrane potential GO:0042391 192 0.039
Mouse
purine containing compound catabolic process GO:0072523 213 0.039
regulation of cytokine production GO:0001817 266 0.039
adaptive immune response GO:0002250 155 0.039
cellular response to cytokine stimulus GO:0071345 189 0.039
t helper 17 cell chemotaxis GO:0035705 1 0.038
regulation of purine nucleotide metabolic process GO:1900542 169 0.037
nitrogen compound transport GO:0071705 271 0.037
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.037
Mouse
regulation of t cell activation GO:0050863 170 0.037
regulation of camp mediated signaling GO:0043949 7 0.037
leukocyte chemotaxis GO:0030595 69 0.037
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.036
Mouse
positive regulation of t cell costimulation GO:2000525 2 0.036
regulation of tube size GO:0035150 57 0.036
Human Mouse
cytokine secretion GO:0050663 72 0.036
calcium ion homeostasis GO:0055074 127 0.036
Human Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.035
response to peptide hormone GO:0043434 127 0.035
regulation of action potential GO:0098900 4 0.035
second messenger mediated signaling GO:0019932 73 0.035
Human Mouse
leukocyte migration GO:0050900 124 0.035
positive regulation of monocyte extravasation GO:2000439 1 0.035
cellular homeostasis GO:0019725 240 0.035
Human Mouse
membrane lipid metabolic process GO:0006643 53 0.034
peptidyl tyrosine phosphorylation GO:0018108 143 0.034
Mouse
detection of abiotic stimulus GO:0009582 60 0.034
spermatogenesis GO:0007283 284 0.033
negative regulation of blood vessel morphogenesis GO:2000181 25 0.033
negative regulation of eosinophil degranulation GO:0043310 1 0.033
glycosyl compound metabolic process GO:1901657 246 0.032
regulation of monocyte chemotaxis GO:0090025 3 0.032
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.032
purine containing compound biosynthetic process GO:0072522 70 0.032
Human Mouse
regulation of monocyte extravasation GO:2000437 2 0.031
positive regulation of camp mediated signaling GO:0043950 3 0.031
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.031
Mouse
erk1 and erk2 cascade GO:0070371 77 0.031
camp biosynthetic process GO:0006171 31 0.031
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.031
cyclic nucleotide biosynthetic process GO:0009190 44 0.031
Human Mouse
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.030
muscle contraction GO:0006936 101 0.030
Human Mouse
wound healing GO:0042060 157 0.030
positive regulation of acute inflammatory response GO:0002675 16 0.030
response to peptide GO:1901652 136 0.030
protein catabolic process GO:0030163 221 0.030
negative regulation of cellular component organization GO:0051129 194 0.030
chemotaxis GO:0006935 247 0.030
c21 steroid hormone biosynthetic process GO:0006700 3 0.029
steroid metabolic process GO:0008202 119 0.029
regulation of smooth muscle contraction GO:0006940 22 0.029
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.029
energy derivation by oxidation of organic compounds GO:0015980 77 0.029
interleukin 6 production GO:0032635 58 0.029
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.029
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.029
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.028
Mouse
cellular response to acid chemical GO:0071229 68 0.028
regulation of fat cell proliferation GO:0070344 4 0.028
regulation of chemotaxis GO:0050920 53 0.028
cellular response to lipopolysaccharide GO:0071222 77 0.028
response to oxidative stress GO:0006979 123 0.028
detection of external stimulus GO:0009581 61 0.028
muscle cell differentiation GO:0042692 261 0.028
regulation of transferase activity GO:0051338 263 0.028
Human Mouse
positive regulation of map kinase activity GO:0043406 84 0.028
Human
hormone secretion GO:0046879 128 0.028
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.028
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.028
Mouse
protein processing GO:0016485 163 0.028
cartilage development GO:0051216 140 0.028
action potential GO:0001508 78 0.028
Mouse
renal system development GO:0072001 225 0.028
skeletal system development GO:0001501 356 0.028
lymphocyte mediated immunity GO:0002449 139 0.028
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.027
response to insulin GO:0032868 100 0.027
cell substrate adhesion GO:0031589 130 0.027
cell matrix adhesion GO:0007160 68 0.027
innate immune response GO:0045087 157 0.027
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.027
male gamete generation GO:0048232 285 0.027
lymphocyte activation involved in immune response GO:0002285 93 0.027
negative regulation of angiogenesis GO:0016525 25 0.027
positive regulation of cytokine secretion GO:0050715 41 0.027
epithelial tube morphogenesis GO:0060562 303 0.027
cation homeostasis GO:0055080 212 0.027
Human Mouse
divalent inorganic cation transport GO:0072511 178 0.027
Human
t cell extravasation GO:0072683 4 0.027
digestive tract development GO:0048565 190 0.027
Mouse
skeletal system morphogenesis GO:0048705 203 0.026
response to alcohol GO:0097305 48 0.026
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.026
negative regulation of cytokine production GO:0001818 84 0.026
cardiac muscle tissue development GO:0048738 130 0.026
lymphocyte proliferation GO:0046651 164 0.026
regulation of cellular catabolic process GO:0031329 242 0.026
nucleoside triphosphate metabolic process GO:0009141 230 0.026
negative regulation of protein metabolic process GO:0051248 282 0.026
purine nucleotide biosynthetic process GO:0006164 65 0.026
Human Mouse
peptidyl amino acid modification GO:0018193 336 0.025
Mouse
generation of precursor metabolites and energy GO:0006091 103 0.025
Mouse
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.025
purine ribonucleoside metabolic process GO:0046128 241 0.025
eosinophil mediated immunity GO:0002447 1 0.025
rho protein signal transduction GO:0007266 32 0.025
regulation of protein serine threonine kinase activity GO:0071900 157 0.025
Human
sensory perception of chemical stimulus GO:0007606 51 0.025
negative regulation of growth GO:0045926 99 0.025
Mouse
t cell differentiation GO:0030217 174 0.025
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.025
Mouse
negative regulation of cell motility GO:2000146 61 0.025
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.025
peptide secretion GO:0002790 114 0.024
Mouse
positive regulation of cell migration GO:0030335 109 0.024
Mouse
myeloid cell differentiation GO:0030099 233 0.024
regulation of nucleotide biosynthetic process GO:0030808 34 0.024
Mouse
regulation of hematopoietic stem cell migration GO:2000471 1 0.024
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.024
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.024
Mouse
negative regulation of molecular function GO:0044092 258 0.024
positive regulation of stress activated mapk cascade GO:0032874 48 0.023
defense response to other organism GO:0098542 197 0.023
sensory perception GO:0007600 245 0.023
ion transmembrane transport GO:0034220 361 0.023
natural killer cell activation GO:0030101 44 0.023
eosinophil activation GO:0043307 1 0.023
positive regulation of chemotaxis GO:0050921 38 0.023
negative regulation of inflammatory response GO:0050728 61 0.023
signal transduction in absence of ligand GO:0038034 55 0.023
neuronal action potential GO:0019228 54 0.023
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.023
membrane lipid biosynthetic process GO:0046467 32 0.023
cell type specific apoptotic process GO:0097285 268 0.023
divalent metal ion transport GO:0070838 172 0.023
Human
regulation of protein kinase b signaling GO:0051896 56 0.022
cellular calcium ion homeostasis GO:0006874 119 0.022
Human Mouse
antibacterial peptide production GO:0002778 2 0.022
regulation of immunological synapse formation GO:2000520 2 0.022
negative regulation of endothelial cell migration GO:0010596 4 0.022
positive regulation of angiogenesis GO:0045766 46 0.022
positive regulation of immune effector process GO:0002699 107 0.021
positive regulation of cell activation GO:0050867 158 0.021
organic anion transport GO:0015711 137 0.021
immunoglobulin production GO:0002377 73 0.021
cytokine production GO:0001816 319 0.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.021
positive regulation of nervous system development GO:0051962 221 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
regulation of interleukin 5 secretion GO:2000662 2 0.021
regulation of reactive oxygen species metabolic process GO:2000377 40 0.021
cellular response to prostaglandin d stimulus GO:0071799 1 0.021
helper t cell chemotaxis GO:0035704 1 0.021
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.021
regulation of lymphocyte activation GO:0051249 240 0.021
kidney development GO:0001822 213 0.021
positive regulation of immunological synapse formation GO:2000522 1 0.021
regulation of anatomical structure size GO:0090066 178 0.021
Human Mouse
regulation of leukocyte differentiation GO:1902105 159 0.021
striated muscle tissue development GO:0014706 293 0.020
stress activated protein kinase signaling cascade GO:0031098 81 0.020
type 2 immune response GO:0042092 23 0.020
progesterone metabolic process GO:0042448 4 0.020
immune complex clearance GO:0002434 2 0.020
cellular polysaccharide metabolic process GO:0044264 38 0.020
peptide transport GO:0015833 133 0.020
Mouse
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.020
endochondral bone growth GO:0003416 19 0.020
cell activation involved in immune response GO:0002263 126 0.020
regulation of lipid transport GO:0032368 36 0.020
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.020
Mouse
regulation of feeding behavior GO:0060259 3 0.020
cell adhesion GO:0007155 329 0.020
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.020
response to oxygen levels GO:0070482 62 0.019
positive regulation of cytokine production GO:0001819 174 0.019
connective tissue development GO:0061448 179 0.019
negative regulation of homeostatic process GO:0032845 71 0.019
Human
monosaccharide transport GO:0015749 58 0.019
Mouse
positive regulation of protein secretion GO:0050714 52 0.019
cellular response to insulin stimulus GO:0032869 78 0.019
positive regulation of cell motility GO:2000147 116 0.019
Mouse
response to radiation GO:0009314 165 0.019
Mouse
response to transforming growth factor beta GO:0071559 88 0.019
negative regulation of secretion GO:0051048 61 0.019
Mouse
regulation of interleukin 13 secretion GO:2000665 2 0.019
regulation of anion transport GO:0044070 27 0.019
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.019
Mouse
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.019
cell chemotaxis GO:0060326 81 0.019
positive regulation of alpha beta t cell activation GO:0046635 39 0.019
t helper 2 cell cytokine production GO:0035745 4 0.018
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.018
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.018
monocyte extravasation GO:0035696 2 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
positive regulation of lipid transport GO:0032370 22 0.018
synaptic transmission GO:0007268 329 0.018
Mouse
negative regulation of cell migration GO:0030336 59 0.018
mesonephros development GO:0001823 97 0.018
cytoplasmic transport GO:0016482 234 0.018
Human Mouse
icosanoid metabolic process GO:0006690 33 0.018
fatty acid metabolic process GO:0006631 121 0.018
negative regulation of iron ion transport GO:0034757 1 0.018
lymphocyte differentiation GO:0030098 242 0.018
regulation of cell cycle GO:0051726 281 0.018
negative regulation of phosphorylation GO:0042326 166 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.018
Mouse
bone morphogenesis GO:0060349 78 0.017
organic hydroxy compound transport GO:0015850 93 0.017
Mouse
calcium ion transport GO:0006816 159 0.017
Human
cellular amino acid metabolic process GO:0006520 103 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
appendage development GO:0048736 166 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
rhodopsin mediated signaling pathway GO:0016056 4 0.017
regulation of erk1 and erk2 cascade GO:0070372 71 0.017
Human
endothelial cell differentiation GO:0045446 41 0.017
glycosylation GO:0070085 62 0.017
transmembrane transport GO:0055085 412 0.017
positive regulation of proteolysis GO:0045862 85 0.017
negative regulation of response to wounding GO:1903035 77 0.017
immune complex clearance by monocytes and macrophages GO:0002436 2 0.017
adult behavior GO:0030534 135 0.017
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.017
positive regulation of intracellular transport GO:0032388 70 0.017
regulation of cytokine secretion GO:0050707 61 0.017
activation of adenylate cyclase activity GO:0007190 4 0.017
Mouse
regulation of interleukin 8 production GO:0032677 3 0.017
positive regulation of nucleotide metabolic process GO:0045981 114 0.017
positive regulation of response to wounding GO:1903036 66 0.017
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.017
macromolecule catabolic process GO:0009057 281 0.016
endochondral bone morphogenesis GO:0060350 50 0.016
dna recombination GO:0006310 92 0.016
cell death in response to oxidative stress GO:0036473 24 0.016
regulation of cell growth GO:0001558 91 0.016
response to light stimulus GO:0009416 135 0.016
Mouse
regulation of blood vessel size GO:0050880 56 0.016
Human Mouse
stress activated mapk cascade GO:0051403 80 0.016
regulation of reproductive process GO:2000241 66 0.016
negative regulation of camp mediated signaling GO:0043951 3 0.016
cellular response to prostaglandin stimulus GO:0071379 2 0.016
heterocycle catabolic process GO:0046700 280 0.016
acid secretion GO:0046717 33 0.016
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
Human Mouse
organic acid biosynthetic process GO:0016053 86 0.016
positive regulation of growth GO:0045927 104 0.016
learning or memory GO:0007611 148 0.016
Mouse
regulation of exocytosis GO:0017157 61 0.016
microglial cell activation involved in immune response GO:0002282 1 0.016
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.016
regulation of production of molecular mediator of immune response GO:0002700 65 0.016
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.016
membrane depolarization GO:0051899 64 0.016
response to nutrient levels GO:0031667 109 0.016
Mouse
interleukin 8 production GO:0032637 4 0.016
regulation of endopeptidase activity GO:0052548 89 0.016
muscle cell proliferation GO:0033002 52 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.016
response to extracellular stimulus GO:0009991 127 0.016
Mouse
intracellular protein transport GO:0006886 204 0.016
Mouse
regulation of ion transmembrane transport GO:0034765 119 0.015
regulation of fat cell differentiation GO:0045598 81 0.015
Mouse
negative regulation of protein processing GO:0010955 79 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
regulation of jnk cascade GO:0046328 62 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
Mouse
regulation of transmembrane transport GO:0034762 128 0.015
response to organic cyclic compound GO:0014070 198 0.015
Mouse
regulation of cellular response to oxidative stress GO:1900407 19 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
interleukin 12 secretion GO:0072610 3 0.015
defense response to virus GO:0051607 68 0.015
stem cell differentiation GO:0048863 268 0.015
alpha beta t cell activation GO:0046631 91 0.015
regulation of defense response to bacterium GO:1900424 3 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
organelle localization GO:0051640 179 0.015
regulation of peptidase activity GO:0052547 96 0.015
dna modification GO:0006304 50 0.015
negative regulation of secretion by cell GO:1903531 54 0.015
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
cell cell recognition GO:0009988 44 0.015
regulation of interferon gamma production GO:0032649 57 0.015
regulation of homeostatic process GO:0032844 182 0.015
Human
reactive nitrogen species metabolic process GO:2001057 0 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
ras protein signal transduction GO:0007265 77 0.015
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.015
regulation of tissue remodeling GO:0034103 38 0.015
polysaccharide metabolic process GO:0005976 39 0.014
male gonad development GO:0008584 88 0.014
cellular response to molecule of bacterial origin GO:0071219 83 0.014
regulation of multi organism process GO:0043900 111 0.014
fat cell proliferation GO:0070341 4 0.014
positive regulation of defense response GO:0031349 124 0.014
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.014
respiratory tube development GO:0030323 167 0.014
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.014
regulation of metal ion transport GO:0010959 106 0.014
Mouse
regulation of lipid biosynthetic process GO:0046890 54 0.014
Human
fatty acid derivative metabolic process GO:1901568 33 0.014
lipid localization GO:0010876 126 0.014
carbohydrate metabolic process GO:0005975 230 0.014
Mouse
response to growth factor GO:0070848 198 0.014
regulated secretory pathway GO:0045055 32 0.014
branching morphogenesis of an epithelial tube GO:0048754 159 0.014
regulation of intracellular transport GO:0032386 159 0.014
positive regulation of vasoconstriction GO:0045907 4 0.014
negative regulation of phospholipase activity GO:0010519 4 0.014
maintenance of location GO:0051235 89 0.014
Human
positive regulation of monocyte chemotaxis GO:0090026 2 0.014
mapk cascade GO:0000165 281 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
regulation of organelle organization GO:0033043 289 0.014
interleukin 13 secretion GO:0072611 2 0.014
myelination GO:0042552 74 0.014
hexose metabolic process GO:0019318 98 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
vascular process in circulatory system GO:0003018 62 0.014
Human Mouse
myeloid leukocyte differentiation GO:0002573 119 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
interferon gamma production GO:0032609 67 0.014
positive regulation of t cell extravasation GO:2000409 2 0.014
positive regulation of phagocytosis GO:0050766 26 0.014
regulation of alpha beta t cell activation GO:0046634 53 0.013
cation transport GO:0006812 399 0.013
Human Mouse
asymmetric stem cell division GO:0098722 3 0.013
positive regulation of leukocyte differentiation GO:1902107 86 0.013
membrane organization GO:0061024 245 0.013
regulation of t cell costimulation GO:2000523 2 0.013
regulation of response to oxidative stress GO:1902882 19 0.013

Htr2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.069
disease of anatomical entity DOID:7 0 0.069
disease of metabolism DOID:0014667 0 0.033
nervous system disease DOID:863 0 0.021
sensory system disease DOID:0050155 0 0.018
eye and adnexa disease DOID:1492 0 0.018
hematopoietic system disease DOID:74 0 0.014