|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.997
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.992
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.973
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.961
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.934
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.917
|
|
|
|
regulation of lymphocyte anergy
|
GO:0002911 |
4 |
0.914
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.841
|
|
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.841
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.817
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.816
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.814
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.796
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.791
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.758
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.740
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.735
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.701
|
|
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.690
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.670
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.669
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.664
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.662
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.658
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.657
|
Mouse |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.645
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.642
|
|
|
|
natural killer cell inhibitory signaling pathway
|
GO:0002769 |
2 |
0.626
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.620
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.611
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.609
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.596
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.584
|
Mouse |
|
|
immune effector process
|
GO:0002252 |
321 |
0.558
|
Mouse |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.554
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.550
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.531
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.528
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.525
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.509
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.498
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.480
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.480
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.478
|
Mouse |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.476
|
Mouse |
|
|
negative t cell selection
|
GO:0043383 |
13 |
0.454
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.452
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.441
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.415
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.410
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.407
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.400
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.396
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.395
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.385
|
Mouse |
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.381
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.375
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.369
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.368
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.360
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.354
|
|
|
|
regulation of t cell anergy
|
GO:0002667 |
4 |
0.354
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.351
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.350
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.350
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.345
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.335
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.328
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.326
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.321
|
|
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.320
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.319
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.317
|
|
|
|
regulation of hematopoietic stem cell migration
|
GO:2000471 |
1 |
0.315
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
12 |
0.314
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.311
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.306
|
|
|
|
regulation of natural killer cell mediated immunity
|
GO:0002715 |
19 |
0.304
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.303
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.300
|
|
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.300
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.299
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.296
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.285
|
|
|
|
interleukin 2 mediated signaling pathway
|
GO:0038110 |
2 |
0.283
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.283
|
Human |
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.282
|
|
|
|
cellular response to interleukin 15
|
GO:0071350 |
2 |
0.282
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.282
|
|
|
|
lymphocyte anergy
|
GO:0002249 |
4 |
0.280
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.273
|
|
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.272
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.269
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.269
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.266
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.266
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.262
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.259
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.258
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.256
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.250
|
|
|
|
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
|
GO:2000526 |
1 |
0.250
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.242
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.238
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.236
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.234
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.234
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.234
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.233
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.231
|
|
|
|
interleukin 4 production
|
GO:0032633 |
24 |
0.230
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.226
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.223
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.223
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.221
|
|
|
|
granzyme mediated apoptotic signaling pathway
|
GO:0008626 |
1 |
0.218
|
|
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
1 |
0.217
|
|
|
|
regulation of natural killer cell mediated cytotoxicity
|
GO:0042269 |
19 |
0.217
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.217
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.216
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.215
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.214
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.213
|
|
|
|
granulocyte activation
|
GO:0036230 |
10 |
0.212
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.209
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.200
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.199
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.198
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.196
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.194
|
Mouse |
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.194
|
|
|
|
cellular response to molecule of fungal origin
|
GO:0071226 |
2 |
0.192
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.191
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.190
|
Mouse |
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.188
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.188
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.187
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.183
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.182
|
|
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.181
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.181
|
Mouse |
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.179
|
Mouse |
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.175
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.175
|
|
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.175
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.174
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.172
|
Human |
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.171
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.171
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.170
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.167
|
Mouse |
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.167
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.167
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.166
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.165
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.164
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.161
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.161
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.159
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.159
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.159
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.158
|
Mouse |
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.157
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.156
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.156
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.155
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.155
|
|
|
|
gamma delta t cell differentiation
|
GO:0042492 |
11 |
0.153
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.153
|
Mouse |
|
|
t cell costimulation
|
GO:0031295 |
14 |
0.152
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.150
|
Mouse |
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.150
|
|
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
16 |
0.149
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.148
|
|
|
|
positive regulation of immune complex clearance by monocytes and macrophages
|
GO:0090265 |
2 |
0.147
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.146
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.145
|
|
|
|
positive regulation of lymphocyte anergy
|
GO:0002913 |
4 |
0.145
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.144
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.144
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.139
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.139
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.138
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.136
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.136
|
|
|
|
t cell mediated cytotoxicity
|
GO:0001913 |
26 |
0.134
|
|
|
|
regulation of t cell mediated cytotoxicity
|
GO:0001914 |
18 |
0.133
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.132
|
Mouse |
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.130
|
|
|
|
natural killer cell mediated immunity
|
GO:0002228 |
29 |
0.129
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.129
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.129
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.129
|
Human |
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.128
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.128
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.127
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.127
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.127
|
Mouse |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.127
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.125
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.123
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.122
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.122
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.120
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.118
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.118
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.117
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.116
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.116
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.116
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.116
|
|
|
|
positive regulation of interleukin 2 biosynthetic process
|
GO:0045086 |
8 |
0.115
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.114
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.114
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.113
|
|
|
|
positive regulation of t cell anergy
|
GO:0002669 |
4 |
0.112
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.112
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.112
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.112
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.110
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.110
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.109
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.108
|
Mouse |
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.108
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.107
|
|
|
|
positive regulation of calcium mediated signaling
|
GO:0050850 |
15 |
0.105
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.103
|
|
|
|
positive thymic t cell selection
|
GO:0045059 |
13 |
0.103
|
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.101
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.101
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.100
|
|
|
|
macrophage activation
|
GO:0042116 |
27 |
0.099
|
|
|
|
positive regulation of inflammatory response to antigenic stimulus
|
GO:0002863 |
11 |
0.099
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.098
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.098
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.097
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.096
|
|
|
|
response to molecule of fungal origin
|
GO:0002238 |
4 |
0.095
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.094
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.093
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.092
|
|
|
|
interleukin 8 secretion
|
GO:0072606 |
3 |
0.092
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.091
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
27 |
0.091
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.091
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.091
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.090
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.089
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.089
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.089
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.088
|
Mouse |
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.087
|
|
|
|
isotype switching to igg isotypes
|
GO:0048291 |
10 |
0.087
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.087
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.086
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.085
|
Mouse |
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.085
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.085
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.085
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.085
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.084
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.084
|
|
|
|
tolerance induction
|
GO:0002507 |
14 |
0.084
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.083
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.082
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.081
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.081
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.080
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.080
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.080
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.080
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.079
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.078
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.078
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.077
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
13 |
0.077
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.076
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.075
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.074
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.074
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.074
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.074
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.072
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.072
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.072
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.072
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.071
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.070
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.070
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.070
|
Mouse |
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.069
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.068
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.067
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.066
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.066
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.066
|
|
|
|
gamma delta t cell lineage commitment
|
GO:0002365 |
1 |
0.065
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.065
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.063
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.063
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.062
|
|
|
|
cellular defense response
|
GO:0006968 |
6 |
0.062
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.062
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.062
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.062
|
|
|
|
lymphocyte costimulation
|
GO:0031294 |
15 |
0.061
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.061
|
|
|
|
detection of bacterial lipoprotein
|
GO:0042494 |
1 |
0.059
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.059
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.059
|
|
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
20 |
0.059
|
|
|
|
regulation of interleukin 8 secretion
|
GO:2000482 |
2 |
0.059
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.058
|
|
|
|
growth of symbiont in host
|
GO:0044117 |
23 |
0.058
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.058
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.057
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.057
|
|
|
|
t cell anergy
|
GO:0002870 |
4 |
0.056
|
|
|
|
fc receptor mediated stimulatory signaling pathway
|
GO:0002431 |
4 |
0.056
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.056
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.056
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.056
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.056
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.056
|
|
|
|
endocrine process
|
GO:0050886 |
39 |
0.055
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.055
|
|
|
|
positive regulation of t cell mediated cytotoxicity
|
GO:0001916 |
15 |
0.055
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.055
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
19 |
0.054
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.054
|
|
|
|
positive regulation of natural killer cell mediated cytotoxicity
|
GO:0045954 |
16 |
0.054
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.054
|
|
|
|
response to interleukin 4
|
GO:0070670 |
23 |
0.054
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.054
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.053
|
|
|
|
fatty acid derivative transport
|
GO:1901571 |
14 |
0.053
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.053
|
|
|
|
detection of yeast
|
GO:0001879 |
2 |
0.053
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.053
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.053
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.052
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.052
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.051
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.051
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.050
|
Mouse |
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.049
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.049
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.049
|
|
|
|
fatty acid transport
|
GO:0015908 |
28 |
0.049
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.048
|
|
|
|
inner cell mass cell proliferation
|
GO:0001833 |
15 |
0.048
|
|
|
|
hypersensitivity
|
GO:0002524 |
10 |
0.048
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.048
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.048
|
|
|
|
sensitization
|
GO:0046960 |
2 |
0.048
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.047
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.047
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.047
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.047
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.046
|
|
|
|
gamma delta t cell activation
|
GO:0046629 |
13 |
0.046
|
|
|
|
negative regulation of lymphocyte apoptotic process
|
GO:0070229 |
24 |
0.046
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.046
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.046
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.046
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.045
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.045
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.045
|
|
|
|
regulation of anion transport
|
GO:0044070 |
27 |
0.045
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.045
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.045
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.045
|
Mouse |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.045
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.044
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.044
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.043
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
38 |
0.043
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.043
|
Mouse |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.042
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.042
|
|
|
|
regulation of interleukin 2 biosynthetic process
|
GO:0045076 |
13 |
0.041
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.041
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.041
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.040
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.040
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.040
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.040
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
27 |
0.040
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.040
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.039
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.039
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.039
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.039
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.039
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.039
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.039
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.039
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.038
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.038
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.038
|
|
|
|
corticotropin releasing hormone secretion
|
GO:0043396 |
2 |
0.038
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.037
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.037
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.037
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.037
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.037
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
17 |
0.037
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.036
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.036
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.036
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.036
|
|
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.036
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.036
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.036
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.036
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.036
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.035
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.035
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.035
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.035
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
31 |
0.035
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.035
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.035
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.035
|
|
|
|
dendritic cell chemotaxis
|
GO:0002407 |
7 |
0.035
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.035
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
41 |
0.035
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.035
|
|
|
|
hexose transport
|
GO:0008645 |
56 |
0.034
|
|
|
|
positive regulation of oligodendrocyte differentiation
|
GO:0048714 |
9 |
0.034
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.034
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.034
|
|
|
|
positive regulation of type iii hypersensitivity
|
GO:0001805 |
3 |
0.034
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.034
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.034
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.034
|
|
|
|
regulation of corticotropin releasing hormone secretion
|
GO:0043397 |
2 |
0.034
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.034
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.034
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.033
|
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
3 |
0.033
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.033
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.033
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.033
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.033
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.033
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.033
|
|
|
|
t cell tolerance induction
|
GO:0002517 |
6 |
0.033
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.033
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.032
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.032
|
|
|
|
regulation of systemic arterial blood pressure mediated by a chemical signal
|
GO:0003044 |
33 |
0.032
|
|
|
|
positive regulation of glial cell differentiation
|
GO:0045687 |
21 |
0.032
|
|
|
|
regulation of hypersensitivity
|
GO:0002883 |
10 |
0.032
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.032
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.032
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.032
|
|
|
|
regulation of acute inflammatory response to antigenic stimulus
|
GO:0002864 |
10 |
0.032
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.031
|
Mouse |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.031
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.031
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.031
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.031
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.031
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.031
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.031
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.031
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.031
|
Mouse |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.031
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.031
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.031
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.031
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.031
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.030
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.030
|
|
|
|
immune response inhibiting signal transduction
|
GO:0002765 |
4 |
0.030
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.030
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.030
|
|
|
|
necroptotic signaling pathway
|
GO:0097527 |
3 |
0.030
|
|
|
|
acute inflammatory response to antigenic stimulus
|
GO:0002438 |
12 |
0.030
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.030
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.030
|
|
|
|
positive regulation of mast cell degranulation
|
GO:0043306 |
10 |
0.030
|
|
|
|
regulation of platelet activation
|
GO:0010543 |
17 |
0.030
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.030
|
|
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
0.029
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.029
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.029
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.029
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.029
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.029
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
11 |
0.029
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.029
|
|
