Mus musculus

179 known processes

Wfs1

Wolfram syndrome 1 homolog (human)

(Aliases: wolframin,AI481085)

Wfs1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.155
cation transport GO:0006812 399 0.116
Human
transmembrane transport GO:0055085 412 0.083
cation transmembrane transport GO:0098655 266 0.074
nucleotide metabolic process GO:0009117 332 0.071
ossification GO:0001503 216 0.068
endomembrane system organization GO:0010256 147 0.065
intracellular protein transport GO:0006886 204 0.063
regulation of cellular amine metabolic process GO:0033238 20 0.060
anion transport GO:0006820 177 0.052
negative regulation of cell proliferation GO:0008285 296 0.052
male gamete generation GO:0048232 285 0.051
amine metabolic process GO:0009308 45 0.047
regulation of neuron differentiation GO:0045664 281 0.047
cellular amine metabolic process GO:0044106 44 0.047
cellular amino acid metabolic process GO:0006520 103 0.046
regulation of neuron projection development GO:0010975 169 0.046
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.045
synaptic transmission GO:0007268 329 0.044
membrane organization GO:0061024 245 0.044
aromatic compound catabolic process GO:0019439 286 0.043
nucleobase containing small molecule metabolic process GO:0055086 352 0.043
cellular ketone metabolic process GO:0042180 84 0.043
purine nucleoside triphosphate metabolic process GO:0009144 226 0.043
developmental maturation GO:0021700 193 0.042
nucleoside phosphate metabolic process GO:0006753 338 0.042
regulation of organelle organization GO:0033043 289 0.041
inorganic ion transmembrane transport GO:0098660 234 0.039
cytoplasmic transport GO:0016482 234 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.039
regulation of cellular component biogenesis GO:0044087 181 0.039
regionalization GO:0003002 337 0.038
ribose phosphate metabolic process GO:0019693 291 0.037
organic cyclic compound catabolic process GO:1901361 295 0.037
inorganic cation transmembrane transport GO:0098662 207 0.036
organonitrogen compound catabolic process GO:1901565 264 0.036
organophosphate catabolic process GO:0046434 232 0.036
regulation of cell projection organization GO:0031344 206 0.035
positive regulation of cellular amine metabolic process GO:0033240 5 0.035
axonogenesis GO:0007409 274 0.035
negative regulation of cellular component organization GO:0051129 194 0.035
regulation of hydrolase activity GO:0051336 246 0.035
regulation of secretion GO:0051046 274 0.035
purine nucleoside catabolic process GO:0006152 205 0.035
ras protein signal transduction GO:0007265 77 0.034
response to radiation GO:0009314 165 0.034
positive regulation of nervous system development GO:0051962 221 0.034
apoptotic signaling pathway GO:0097190 306 0.034
macromolecule catabolic process GO:0009057 281 0.033
purine nucleotide metabolic process GO:0006163 302 0.033
response to growth factor GO:0070848 198 0.033
glycosyl compound catabolic process GO:1901658 206 0.033
positive regulation of programmed cell death GO:0043068 218 0.033
carbohydrate derivative catabolic process GO:1901136 231 0.032
localization within membrane GO:0051668 4 0.032
oxidation reduction process GO:0055114 342 0.032
positive regulation of apoptotic process GO:0043065 217 0.032
positive regulation of organelle organization GO:0010638 128 0.032
negative regulation of intracellular signal transduction GO:1902532 167 0.031
glycosyl compound metabolic process GO:1901657 246 0.031
ribonucleotide catabolic process GO:0009261 208 0.031
regulation of protein localization GO:0032880 231 0.031
negative regulation of molecular function GO:0044092 258 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.031
purine containing compound catabolic process GO:0072523 213 0.031
cellular response to growth factor stimulus GO:0071363 197 0.031
mapk cascade GO:0000165 281 0.030
neurotransmitter transport GO:0006836 76 0.029
cell adhesion GO:0007155 329 0.029
purine ribonucleotide metabolic process GO:0009150 290 0.028
regulation of cellular amino acid metabolic process GO:0006521 5 0.028
regulation of defense response GO:0031347 233 0.028
ribonucleotide metabolic process GO:0009259 291 0.028
organelle localization GO:0051640 179 0.028
carbohydrate derivative biosynthetic process GO:1901137 183 0.028
cellular nitrogen compound catabolic process GO:0044270 280 0.028
regulation of protein transport GO:0051223 163 0.028
ribonucleoside triphosphate metabolic process GO:0009199 220 0.027
negative regulation of phosphate metabolic process GO:0045936 184 0.027
divalent inorganic cation transport GO:0072511 178 0.027
Human
sodium ion transport GO:0006814 73 0.027
regulation of secretion by cell GO:1903530 249 0.027
cellular chemical homeostasis GO:0055082 215 0.027
Human
regulation of transmembrane transport GO:0034762 128 0.026
nitrogen compound transport GO:0071705 271 0.026
spermatogenesis GO:0007283 284 0.026
positive regulation of cell development GO:0010720 237 0.026
purine containing compound metabolic process GO:0072521 311 0.026
positive regulation of protein modification process GO:0031401 299 0.026
organelle assembly GO:0070925 177 0.026
gland development GO:0048732 330 0.026
exocytosis GO:0006887 121 0.026
meiotic cell cycle GO:0051321 122 0.026
divalent metal ion transport GO:0070838 172 0.025
Human
cellular lipid metabolic process GO:0044255 323 0.025
negative regulation of growth GO:0045926 99 0.025
sensory perception GO:0007600 245 0.025
Human
purine ribonucleoside catabolic process GO:0046130 205 0.025
nucleoside triphosphate catabolic process GO:0009143 205 0.025
protein catabolic process GO:0030163 221 0.025
organic acid transport GO:0015849 101 0.025
t cell activation GO:0042110 289 0.025
acetylcholine transport GO:0015870 2 0.024
response to oxidative stress GO:0006979 123 0.024
ribonucleoside metabolic process GO:0009119 245 0.024
cellular homeostasis GO:0019725 240 0.024
Human
endocytosis GO:0006897 168 0.024
cognition GO:0050890 149 0.024
heterocycle catabolic process GO:0046700 280 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
calcium ion transport GO:0006816 159 0.023
Human
regulation of establishment of protein localization GO:0070201 181 0.023
digestive system development GO:0055123 200 0.023
forebrain development GO:0030900 302 0.023
nucleoside metabolic process GO:0009116 246 0.023
locomotory behavior GO:0007626 195 0.023
regulation of exocytosis GO:0017157 61 0.023
negative regulation of phosphorus metabolic process GO:0010563 184 0.023
cell growth GO:0016049 130 0.023
nucleoside catabolic process GO:0009164 206 0.023
regulation of ion transport GO:0043269 215 0.023
Human
regulation of cell cycle GO:0051726 281 0.023
small gtpase mediated signal transduction GO:0007264 97 0.023
learning or memory GO:0007611 148 0.023
muscle system process GO:0003012 141 0.022
regulation of cell growth GO:0001558 91 0.022
nucleotide catabolic process GO:0009166 217 0.022
rhodopsin mediated signaling pathway GO:0016056 4 0.022
multicellular organismal homeostasis GO:0048871 164 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
organic hydroxy compound metabolic process GO:1901615 203 0.022
cellular protein complex assembly GO:0043623 116 0.022
positive regulation of cell death GO:0010942 224 0.022
purine nucleoside metabolic process GO:0042278 241 0.022
regulation of cellular response to growth factor stimulus GO:0090287 82 0.021
protein localization to membrane GO:0072657 108 0.021
regulation of cell motility GO:2000145 236 0.021
protein targeting GO:0006605 143 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
carboxylic acid transport GO:0046942 100 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
regulation of anatomical structure size GO:0090066 178 0.021
connective tissue development GO:0061448 179 0.021
response to organonitrogen compound GO:0010243 246 0.021
peptidyl amino acid modification GO:0018193 336 0.021
regulation of cellular ketone metabolic process GO:0010565 66 0.020
negative regulation of cellular catabolic process GO:0031330 47 0.020
nucleocytoplasmic transport GO:0006913 139 0.020
respiratory system development GO:0060541 190 0.020
nucleoside monophosphate metabolic process GO:0009123 85 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
regulation of cell activation GO:0050865 289 0.020
striated muscle tissue development GO:0014706 293 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.020
g protein coupled receptor signaling pathway GO:0007186 243 0.020
positive regulation of cellular catabolic process GO:0031331 148 0.020
regulation of ion transmembrane transporter activity GO:0032412 54 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
regulation of transferase activity GO:0051338 263 0.020
skeletal system development GO:0001501 356 0.020
dephosphorylation GO:0016311 129 0.020
regulation of kinase activity GO:0043549 249 0.020
regulation of ossification GO:0030278 112 0.020
myeloid cell differentiation GO:0030099 233 0.019
metal ion homeostasis GO:0055065 189 0.019
Human
carbohydrate metabolic process GO:0005975 230 0.019
amino acid transmembrane transport GO:0003333 37 0.019
regulation of nucleotide catabolic process GO:0030811 122 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
chemotaxis GO:0006935 247 0.019
regulation of vesicle mediated transport GO:0060627 139 0.019
cell maturation GO:0048469 127 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.019
regulation of system process GO:0044057 200 0.019
neuromuscular process GO:0050905 99 0.019
camera type eye development GO:0043010 266 0.019
establishment of vesicle localization GO:0051650 81 0.019
rho protein signal transduction GO:0007266 32 0.019
lymphocyte proliferation GO:0046651 164 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
muscle contraction GO:0006936 101 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
vesicle localization GO:0051648 86 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
microtubule based process GO:0007017 236 0.018
ubiquitin dependent protein catabolic process GO:0006511 129 0.018
regulation of ion transmembrane transport GO:0034765 119 0.018
dna metabolic process GO:0006259 303 0.018
sequestering of calcium ion GO:0051208 18 0.018
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.018
negative regulation of cell development GO:0010721 169 0.018
muscle tissue development GO:0060537 308 0.018
ventricular cardiac muscle cell action potential GO:0086005 4 0.018
protein localization to organelle GO:0033365 185 0.018
regulation of metal ion transport GO:0010959 106 0.018
Human
regulation of protein catabolic process GO:0042176 108 0.018
plasma membrane organization GO:0007009 90 0.017
organic anion transport GO:0015711 137 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
regulation of multi organism process GO:0043900 111 0.017
striated muscle contraction GO:0006941 45 0.017
actin cytoskeleton organization GO:0030036 220 0.017
positive regulation of neuron projection development GO:0010976 79 0.017
compound eye development GO:0048749 1 0.017
anatomical structure homeostasis GO:0060249 145 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.017
metencephalon development GO:0022037 89 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
leukocyte differentiation GO:0002521 342 0.017
morphogenesis of a branching structure GO:0001763 203 0.017
cation homeostasis GO:0055080 212 0.017
Human
regulation of intracellular transport GO:0032386 159 0.017
meiotic nuclear division GO:0007126 115 0.017
nuclear transport GO:0051169 139 0.017
cytokine production GO:0001816 319 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
protein localization to nucleus GO:0034504 121 0.017
positive regulation of cell motility GO:2000147 116 0.016
cardiac muscle cell contraction GO:0086003 7 0.016
regulation of cytokine production GO:0001817 266 0.016
cellular response to epidermal growth factor stimulus GO:0071364 4 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
muscle cell differentiation GO:0042692 261 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
negative regulation of immune system process GO:0002683 209 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
immune effector process GO:0002252 321 0.016
pole plasm assembly GO:0007315 2 0.016
organelle fission GO:0048285 170 0.016
positive regulation of neuron differentiation GO:0045666 141 0.016
pigmentation GO:0043473 71 0.016
intracellular mrna localization GO:0008298 4 0.016
regulation of mapk cascade GO:0043408 248 0.016
establishment of mitochondrion localization GO:0051654 4 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
acetate ester transport GO:1901374 2 0.016
regulation of proteolysis GO:0030162 164 0.016
sequestering of metal ion GO:0051238 19 0.016
regulation of hormone levels GO:0010817 211 0.016
positive regulation of cellular component biogenesis GO:0044089 94 0.016
calcium ion transmembrane transport GO:0070588 85 0.016
nuclear division GO:0000280 158 0.016
regulation of membrane potential GO:0042391 192 0.016
vesicle organization GO:0016050 60 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.015
Human
negative regulation of nervous system development GO:0051961 156 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
l amino acid transport GO:0015807 32 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
protein maturation GO:0051604 176 0.015
striated muscle myosin thick filament assembly GO:0071688 1 0.015
acetylcholine secretion neurotransmission GO:0014055 2 0.015
regulation of transporter activity GO:0032409 57 0.015
homeostasis of number of cells GO:0048872 210 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
synapse organization GO:0050808 125 0.015
positive regulation of defense response GO:0031349 124 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
establishment of organelle localization GO:0051656 122 0.015
mitochondrion distribution GO:0048311 4 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
germ cell development GO:0007281 185 0.015
inflammatory response GO:0006954 244 0.015
positive regulation of protein catabolic process GO:0045732 60 0.015
negative regulation of cell cycle GO:0045786 123 0.015
b cell activation GO:0042113 161 0.015
regulation of protein complex assembly GO:0043254 83 0.015
innate immune response GO:0045087 157 0.015
lateral inhibition GO:0046331 1 0.015
regulation of protein kinase activity GO:0045859 232 0.015
lateral line system development GO:0048925 1 0.015
regulation of cell cycle process GO:0010564 160 0.015
regulation of cell migration GO:0030334 219 0.014
response to lipopolysaccharide GO:0032496 128 0.014
negative regulation of protein modification process GO:0031400 163 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.014
biomineral tissue development GO:0031214 64 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
Human
l alpha amino acid transmembrane transport GO:1902475 23 0.014
oocyte axis specification GO:0007309 2 0.014
regulation of neurotransmitter levels GO:0001505 87 0.014
bone development GO:0060348 120 0.014
regulation of t cell activation GO:0050863 170 0.014
regulation of intracellular protein transport GO:0033157 82 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
protein processing GO:0016485 163 0.014
morphogenesis of a branching epithelium GO:0061138 193 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
heart contraction GO:0060047 93 0.014
cell type specific apoptotic process GO:0097285 268 0.014
action potential GO:0001508 78 0.014
angiogenesis GO:0001525 201 0.014
maintenance of location GO:0051235 89 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
atp metabolic process GO:0046034 75 0.014
stem cell differentiation GO:0048863 268 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
neuron projection guidance GO:0097485 141 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
meiotic cell cycle process GO:1903046 77 0.014
leukocyte migration GO:0050900 124 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
negative regulation of phosphorylation GO:0042326 166 0.013
cellular ion homeostasis GO:0006873 165 0.013
Human
positive regulation of protein kinase activity GO:0045860 144 0.013
extracellular matrix organization GO:0030198 147 0.013
memory GO:0007613 58 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
positive regulation of cell migration GO:0030335 109 0.013
oocyte construction GO:0007308 2 0.013
maternal determination of anterior posterior axis embryo GO:0008358 2 0.013
blood vessel morphogenesis GO:0048514 285 0.013
extracellular structure organization GO:0043062 148 0.013
blood circulation GO:0008015 195 0.013
tissue remodeling GO:0048771 102 0.013
gtp catabolic process GO:0006184 143 0.013
wnt signaling pathway GO:0016055 188 0.013
golgi vesicle transport GO:0048193 30 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
sensory system development GO:0048880 3 0.013
neurotransmitter secretion GO:0007269 62 0.013
glycoprotein metabolic process GO:0009100 116 0.013
neuron neuron synaptic transmission GO:0007270 69 0.013
protein localization to plasma membrane GO:0072659 57 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
tube formation GO:0035148 140 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
digestive tract morphogenesis GO:0048546 147 0.013
negative regulation of purine nucleotide catabolic process GO:0033122 9 0.013
leukocyte proliferation GO:0070661 172 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
mitochondrion organization GO:0007005 134 0.013
retrograde vesicle mediated transport golgi to er GO:0006890 1 0.013
nuclear import GO:0051170 95 0.013
cytoskeleton dependent intracellular transport GO:0030705 50 0.013
regulation of body fluid levels GO:0050878 162 0.013
Human
protein glycosylation GO:0006486 55 0.013
negative regulation of wnt signaling pathway GO:0030178 73 0.013
glucose homeostasis GO:0042593 128 0.013
Human
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.013
organic hydroxy compound transport GO:0015850 93 0.013
positive regulation of secretion by cell GO:1903532 114 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
myosin filament assembly GO:0031034 2 0.013
response to extracellular stimulus GO:0009991 127 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
pallium development GO:0021543 120 0.012
positive regulation of kinase activity GO:0033674 155 0.012
anion transmembrane transport GO:0098656 71 0.012
lipid biosynthetic process GO:0008610 179 0.012
regulation of organ morphogenesis GO:2000027 144 0.012
myosin filament organization GO:0031033 3 0.012
skin development GO:0043588 220 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
dendrite development GO:0016358 115 0.012
glycosylation GO:0070085 62 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.012
telencephalon development GO:0021537 186 0.012
vacuole organization GO:0007033 38 0.012
macromolecule glycosylation GO:0043413 55 0.012
response to inorganic substance GO:0010035 96 0.012
defense response to other organism GO:0098542 197 0.012
regulation of actin filament based process GO:0032970 99 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
protein import into nucleus GO:0006606 95 0.012
t cell proliferation GO:0042098 120 0.012
positive regulation of cell cycle GO:0045787 92 0.012
cellular response to oxidative stress GO:0034599 76 0.012
spermatid differentiation GO:0048515 115 0.012
positive regulation of proteolysis GO:0045862 85 0.012
sulfur compound metabolic process GO:0006790 100 0.012
synaptic vesicle transport GO:0048489 57 0.012
microtubule based transport GO:0010970 50 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
chondrocyte differentiation GO:0002062 72 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
cerebellum development GO:0021549 77 0.012
cell substrate adhesion GO:0031589 130 0.012
wound healing GO:0042060 157 0.012
telencephalon cell migration GO:0022029 55 0.012
protein modification by small protein conjugation or removal GO:0070647 207 0.012
regulation of purine nucleotide catabolic process GO:0033121 122 0.012
rhythmic process GO:0048511 174 0.012
calcium ion homeostasis GO:0055074 127 0.012
Human
regulation of muscle contraction GO:0006937 49 0.012
female gamete generation GO:0007292 74 0.012
amino acid transport GO:0006865 61 0.012
protein import GO:0017038 101 0.012
positive regulation of transferase activity GO:0051347 167 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
protein ubiquitination GO:0016567 171 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
cell chemotaxis GO:0060326 81 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
positive regulation of cell adhesion GO:0045785 80 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
cellular response to hormone stimulus GO:0032870 150 0.011
retrograde transport endosome to golgi GO:0042147 2 0.011
inter male aggressive behavior GO:0002121 3 0.011
lipid transport GO:0006869 98 0.011
renal system development GO:0072001 225 0.011
Human
microtubule based movement GO:0007018 84 0.011
sensory organ morphogenesis GO:0090596 242 0.011
regulation of mitochondrial fission GO:0090140 3 0.011
multi multicellular organism process GO:0044706 109 0.011
digestive tract development GO:0048565 190 0.011
stem cell development GO:0048864 219 0.011
tissue homeostasis GO:0001894 115 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
Human
amide transport GO:0042886 138 0.011
regulation of circadian rhythm GO:0042752 58 0.011
regulation of homeostatic process GO:0032844 182 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
adaptive immune response GO:0002250 155 0.011
regulation of cellular component size GO:0032535 121 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
heart morphogenesis GO:0003007 178 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
regulation of muscle system process GO:0090257 80 0.011
erk1 and erk2 cascade GO:0070371 77 0.011
hormone secretion GO:0046879 128 0.011
heart process GO:0003015 94 0.011
ameboidal type cell migration GO:0001667 128 0.011
single organism cell adhesion GO:0098602 156 0.011
inclusion body assembly GO:0070841 3 0.011
cellular response to arsenic containing substance GO:0071243 4 0.011
epithelial cell proliferation GO:0050673 174 0.011
single organism nuclear import GO:1902593 95 0.011
response to endoplasmic reticulum stress GO:0034976 53 0.011
response to transforming growth factor beta GO:0071559 88 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
copii coated vesicle budding GO:0090114 2 0.010
nucleotide biosynthetic process GO:0009165 78 0.010
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.010
activation of mapkkk activity GO:0000185 1 0.010
regulation of feeding behavior GO:0060259 3 0.010
smoothened signaling pathway GO:0007224 105 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010
negative regulation of cell activation GO:0050866 111 0.010
circulatory system process GO:0003013 197 0.010
establishment of synaptic vesicle localization GO:0097480 57 0.010
positive regulation of necrotic cell death GO:0010940 1 0.010
positive regulation of atpase activity GO:0032781 3 0.010
cell matrix adhesion GO:0007160 68 0.010
cellular response to biotic stimulus GO:0071216 92 0.010
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.010
positive regulation of secretion GO:0051047 130 0.010
response to epidermal growth factor GO:0070849 4 0.010
nucleoside phosphate biosynthetic process GO:1901293 79 0.010
response to peptide GO:1901652 136 0.010
response to organic cyclic compound GO:0014070 198 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.010
regulation of synaptic plasticity GO:0048167 87 0.010
regulation of removal of superoxide radicals GO:2000121 4 0.010
atp catabolic process GO:0006200 55 0.010
appendage development GO:0048736 166 0.010

Wfs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.059
disease of anatomical entity DOID:7 0 0.059
musculoskeletal system disease DOID:17 0 0.059
muscle tissue disease DOID:66 0 0.059
myopathy DOID:423 0 0.053
cardiovascular system disease DOID:1287 0 0.038
disease of metabolism DOID:0014667 0 0.034
Human
inherited metabolic disorder DOID:655 0 0.034
immune system disease DOID:2914 0 0.031
heart disease DOID:114 0 0.023
cardiomyopathy DOID:0050700 0 0.020
intrinsic cardiomyopathy DOID:0060036 0 0.020
nervous system disease DOID:863 0 0.020
neuromuscular disease DOID:440 0 0.018
neuropathy DOID:870 0 0.018
central nervous system disease DOID:331 0 0.013
hematopoietic system disease DOID:74 0 0.012
charcot marie tooth disease DOID:10595 0 0.011