|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.939
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.851
|
Mouse Fly |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.788
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.708
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.666
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.631
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.614
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.601
|
Zebrafish Fly |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.582
|
Human |
|
|
regionalization
|
GO:0003002 |
337 |
0.578
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.574
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.566
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.559
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.558
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.545
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.529
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.524
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.522
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.519
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.502
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.492
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.468
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.467
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.457
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.450
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.444
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.437
|
Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.433
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.431
|
Fly |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.425
|
Mouse Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.424
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.422
|
Rat Fly |
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.412
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.409
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.409
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.408
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.407
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.404
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.376
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.373
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.371
|
Fly |
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.368
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.367
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.361
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.359
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.355
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.349
|
Mouse |
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.349
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.343
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.341
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.340
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.335
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.334
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.313
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.310
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.299
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.299
|
Fly |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.296
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.296
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.290
|
Zebrafish Fly |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.289
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.282
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.280
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.274
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.274
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.271
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.266
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.264
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.262
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.256
|
Fly |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.253
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.251
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.250
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.248
|
Mouse Fly |
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.247
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.244
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.244
|
Mouse |
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.243
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.240
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.238
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.235
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
4 |
0.234
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.234
|
|
|
|
long term memory
|
GO:0007616 |
15 |
0.234
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
57 |
0.231
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.228
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.222
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.221
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.219
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.217
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.217
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.216
|
Fly |
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.211
|
Mouse |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.211
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.209
|
|
|
|
cardiac muscle hypertrophy in response to stress
|
GO:0014898 |
10 |
0.208
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.207
|
|
|
|
mitochondrion transport along microtubule
|
GO:0047497 |
3 |
0.207
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.203
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.202
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.202
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.201
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.201
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.199
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.198
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
29 |
0.198
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.198
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.197
|
Fly |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.197
|
Mouse |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.196
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.193
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.191
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.191
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.190
|
Mouse |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.189
|
Zebrafish Fly |
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.188
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.188
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.187
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.186
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.185
|
Mouse |
|
|
chromatin modification
|
GO:0016568 |
187 |
0.182
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.181
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.179
|
Mouse |
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.177
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.177
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.177
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.176
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.176
|
Fly |
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.176
|
Zebrafish Mouse Fly |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.176
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.176
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.175
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.174
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.174
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.173
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.173
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.173
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.173
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.172
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.171
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.170
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.168
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.167
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.167
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.166
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.162
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.162
|
Mouse Fly |
|
|
olfactory learning
|
GO:0008355 |
2 |
0.161
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.160
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.160
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.158
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.158
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.158
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.153
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.153
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.153
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.152
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.149
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.147
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.147
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.145
|
Mouse |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.145
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.145
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.144
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.143
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.141
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.141
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.140
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.140
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.140
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.139
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.138
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.137
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.136
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.136
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.135
|
Fly |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.135
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.135
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.134
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.134
|
Zebrafish |
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.133
|
Zebrafish |
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.133
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.132
|
|
|
|
regulation of neurotransmitter transport
|
GO:0051588 |
35 |
0.131
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.131
|
|
|
|
adherens junction assembly
|
GO:0034333 |
22 |
0.130
|
Mouse |
|
|
heart contraction
|
GO:0060047 |
93 |
0.130
|
|
|
|
dendritic spine development
|
GO:0060996 |
30 |
0.128
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.128
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.128
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.128
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.127
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.126
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.125
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.125
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.125
|
Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.125
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.124
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.124
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.124
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.124
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.124
|
|
|
|
nucleus localization
|
GO:0051647 |
20 |
0.124
|
Mouse Fly |
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.123
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.122
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.121
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.120
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.120
|
Mouse Fly |
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.119
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.119
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.117
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.116
|
|
|
|
cellular response to osmotic stress
|
GO:0071470 |
7 |
0.115
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.114
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.114
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.112
|
Fly |
|
|
exocytosis
|
GO:0006887 |
121 |
0.112
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.112
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.111
|
Rat Fly |
|
|
cell division
|
GO:0051301 |
120 |
0.110
|
Fly |
|
|
striated muscle adaptation
|
GO:0014888 |
26 |
0.110
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.109
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.109
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.108
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.108
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.107
|
Fly |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.107
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.107
|
|
|
|
positive regulation of necrotic cell death
|
GO:0010940 |
1 |
0.107
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.107
|
Mouse Fly |
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.106
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.106
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.106
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.106
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.105
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.104
|
Zebrafish Fly |
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.104
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.104
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.103
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.103
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.103
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.103
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.103
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.103
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.101
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.101
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.101
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.099
|
Mouse |
|
|
germ cell development
|
GO:0007281 |
185 |
0.098
|
Fly |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.098
|
|
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.097
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.096
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.096
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.096
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.095
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.095
|
|
|
|
apical constriction
|
GO:0003383 |
4 |
0.094
|
Mouse Fly |
|
|
memory
|
GO:0007613 |
58 |
0.094
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.093
|
Fly |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.093
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.093
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.093
|
Mouse |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.092
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
47 |
0.092
|
Mouse |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.091
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.091
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.091
|
Mouse |
|
|
jnk cascade
|
GO:0007254 |
72 |
0.090
|
|
|
|
ventricular cardiac myofibril assembly
|
GO:0055005 |
3 |
0.089
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.089
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.089
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.089
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.088
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.088
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.088
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.087
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.086
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.085
|
Fly |
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.085
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.085
|
Fly |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.084
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
39 |
0.084
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.083
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.082
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.081
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.080
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.080
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.080
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.080
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.079
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.079
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.079
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.078
|
|
|
|
regulation of muscle hypertrophy
|
GO:0014743 |
13 |
0.078
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.077
|
|
|
|
learning
|
GO:0007612 |
98 |
0.077
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.077
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.077
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.076
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.076
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.076
|
|
|
|
cellular response to drug
|
GO:0035690 |
15 |
0.076
|
|
|
|
myelination in peripheral nervous system
|
GO:0022011 |
19 |
0.076
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.075
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.074
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.074
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.074
|
Mouse Fly |
|
|
associative learning
|
GO:0008306 |
61 |
0.074
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.074
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.074
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.074
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.074
|
Mouse |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.074
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.073
|
Mouse Fly |
|
|
nephron development
|
GO:0072006 |
109 |
0.073
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.073
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.073
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.073
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.072
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.072
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.072
|
Fly |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.072
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.072
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.072
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.071
|
Fly |
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.071
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.071
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.070
|
|
|
|
adherens junction organization
|
GO:0034332 |
28 |
0.070
|
Mouse |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.070
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.069
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
15 |
0.069
|
Mouse Fly |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.069
|
|
|
|
regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity
|
GO:0031585 |
2 |
0.069
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.069
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.068
|
Fly |
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.068
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.068
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.067
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.067
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.067
|
|
|
|
male courtship behavior
|
GO:0008049 |
2 |
0.067
|
|
|
|
establishment of spindle localization
|
GO:0051293 |
19 |
0.066
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.066
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.066
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.066
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.065
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.065
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.064
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.064
|
|
|
|
regulation of behavioral fear response
|
GO:2000822 |
2 |
0.063
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.063
|
Human Fly |
|
|
peripheral nervous system development
|
GO:0007422 |
53 |
0.063
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.063
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.063
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
59 |
0.063
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.063
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.063
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.063
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.063
|
|
|
|
positive regulation of potassium ion transport
|
GO:0043268 |
3 |
0.063
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.063
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.062
|
Fly |
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.062
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.062
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.061
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.061
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.061
|
|
|
|
regulation of dna dependent dna replication
|
GO:0090329 |
8 |
0.061
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.060
|
Human |
|
|
histone modification
|
GO:0016570 |
159 |
0.060
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.060
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.060
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.059
|
Fly |
|
|
cytokinesis
|
GO:0000910 |
17 |
0.059
|
Fly |
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.058
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.058
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.058
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.058
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.057
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.057
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.057
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.056
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.056
|
|
|
|
protein glycosylation
|
GO:0006486 |
55 |
0.056
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.056
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.056
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.055
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.055
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.055
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.055
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.055
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.055
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
19 |
0.055
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.055
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.055
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.055
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.054
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.054
|
Fly |
|
|
embryonic body morphogenesis
|
GO:0010172 |
10 |
0.054
|
Worm |
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.054
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.053
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.053
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.053
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.053
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.053
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.053
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.053
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
27 |
0.053
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
21 |
0.052
|
Fly |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.052
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
29 |
0.052
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.052
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.052
|
Mouse |
|
|
forebrain development
|
GO:0030900 |
302 |
0.052
|
|
|
|
regulation of voltage gated calcium channel activity
|
GO:1901385 |
4 |
0.052
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.052
|
|
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.051
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.051
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.051
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.051
|
Zebrafish Fly |
|
|
regulation of mitochondrial membrane permeability
|
GO:0046902 |
17 |
0.051
|
|
|
|
cardiac muscle hypertrophy
|
GO:0003300 |
23 |
0.051
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.051
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.050
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.050
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.050
|
|
|
|
positive regulation of myeloid cell apoptotic process
|
GO:0033034 |
4 |
0.050
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.049
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.049
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.049
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
55 |
0.048
|
|
|
|
midgut development
|
GO:0007494 |
4 |
0.048
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.048
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.048
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.048
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.048
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.048
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.048
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.048
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.047
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.047
|
|
|
|
positive regulation of ion transmembrane transport
|
GO:0034767 |
24 |
0.047
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.047
|
|
|
|
chromatin mediated maintenance of transcription
|
GO:0048096 |
2 |
0.047
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.047
|
Rat Fly |
|
|
neural tube formation
|
GO:0001841 |
108 |
0.047
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.046
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.046
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.046
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.046
|
|
|
|
positive regulation of ion transmembrane transporter activity
|
GO:0032414 |
15 |
0.045
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.045
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.045
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.045
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.045
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.044
|
Zebrafish |
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.044
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
31 |
0.044
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.044
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.044
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.044
|
|
|
|
defecation
|
GO:0030421 |
1 |
0.044
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.043
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.043
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.043
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.042
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.042
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.041
|
Fly |
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.041
|
Fly |
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.041
|
|
|
|
neuromuscular process controlling balance
|
GO:0050885 |
59 |
0.040
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.040
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.040
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.040
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.040
|
|
|
|
potassium ion transport
|
GO:0006813 |
52 |
0.040
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.040
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.040
|
Zebrafish |
|
|
response to radiation
|
GO:0009314 |
165 |
0.040
|
|
|
|
schwann cell development
|
GO:0014044 |
22 |
0.039
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
19 |
0.039
|
Mouse |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.039
|
Fly |
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.039
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.039
|
|
|
|
hippo signaling
|
GO:0035329 |
11 |
0.039
|
|
|
|
lipid phosphorylation
|
GO:0046834 |
25 |
0.039
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.039
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.038
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.038
|
|
