Mus musculus

132 known processes

Bbs1

Bardet-Biedl syndrome 1 (human)

(Aliases: D19Ertd609e,AI451249)

Bbs1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of melanosome localization GO:0032401 11 1.000
melanosome localization GO:0032400 12 0.998
pigment granule transport GO:0051904 12 0.996
cilium assembly GO:0042384 81 0.996
melanosome transport GO:0032402 11 0.995
pigment granule localization GO:0051875 13 0.994
establishment of pigment granule localization GO:0051905 12 0.993
nonmotile primary cilium assembly GO:0035058 8 0.982
cilium morphogenesis GO:0060271 102 0.980
regulation of cilium assembly GO:1902017 7 0.968
cellular response to leptin stimulus GO:0044320 6 0.927
cellular component assembly involved in morphogenesis GO:0010927 139 0.831
pigmentation GO:0043473 71 0.783
cilium dependent cell motility GO:0060285 6 0.767
regulation of cilium beat frequency involved in ciliary motility GO:0060296 5 0.701
cilium movement involved in cell motility GO:0060294 5 0.693
vesicle localization GO:0051648 86 0.684
cellular pigmentation GO:0033059 20 0.665
cilium or flagellum dependent cell motility GO:0001539 6 0.646
establishment of vesicle localization GO:0051650 81 0.624
regulation of appetite GO:0032098 12 0.569
smoothened signaling pathway GO:0007224 105 0.532
photoreceptor cell maintenance GO:0045494 19 0.508
regulation of cilium movement GO:0003352 6 0.495
cilium movement GO:0003341 28 0.478
regulation of cilium movement involved in cell motility GO:0060295 5 0.457
retina homeostasis GO:0001895 23 0.455
microtubule anchoring at microtubule organizing center GO:0072393 5 0.444
organelle assembly GO:0070925 177 0.442
regulation of response to food GO:0032095 10 0.432
fat cell differentiation GO:0045444 160 0.431
digestive tract morphogenesis GO:0048546 147 0.419
microtubule based movement GO:0007018 84 0.418
response to food GO:0032094 17 0.395
regulation of cilium dependent cell motility GO:1902019 5 0.366
axoneme assembly GO:0035082 15 0.335
organelle localization GO:0051640 179 0.331
determination of left right symmetry GO:0007368 80 0.311
gastrulation GO:0007369 116 0.302
digestive tract development GO:0048565 190 0.300
negative regulation of response to food GO:0032096 7 0.278
regulation of microtubule based movement GO:0060632 8 0.275
digestive system development GO:0055123 200 0.259
sensory perception GO:0007600 245 0.254
skeletal system development GO:0001501 356 0.249
eye photoreceptor cell differentiation GO:0001754 41 0.240
striatum development GO:0021756 14 0.231
photoreceptor cell differentiation GO:0046530 52 0.228
protein localization to organelle GO:0033365 185 0.225
Worm
appendage development GO:0048736 166 0.225
spermatid development GO:0007286 108 0.208
notch signaling pathway GO:0007219 71 0.205
eye photoreceptor cell development GO:0042462 31 0.195
establishment of organelle localization GO:0051656 122 0.180
negative regulation of appetite GO:0032099 7 0.178
forebrain development GO:0030900 302 0.170
subpallium development GO:0021544 20 0.169
wnt signaling pathway GO:0016055 188 0.167
cytokine mediated signaling pathway GO:0019221 115 0.165
sensory organ morphogenesis GO:0090596 242 0.161
cerebral cortex development GO:0021987 86 0.153
telencephalon development GO:0021537 186 0.147
spermatogenesis GO:0007283 284 0.143
brain morphogenesis GO:0048854 32 0.140
axis elongation involved in somitogenesis GO:0090245 4 0.138
multicellular organismal homeostasis GO:0048871 164 0.138
sensory perception of smell GO:0007608 26 0.128
regulation of smoothened signaling pathway GO:0008589 58 0.127
regulation of microtubule based process GO:0032886 52 0.119
spermatid differentiation GO:0048515 115 0.118
intraciliary transport GO:0042073 9 0.117
Worm
microtubule cytoskeleton organization GO:0000226 157 0.115
regionalization GO:0003002 337 0.110
eye pigmentation GO:0048069 3 0.109
pallium development GO:0021543 120 0.108
primary neural tube formation GO:0014020 95 0.108
cellular response to cytokine stimulus GO:0071345 189 0.107
anatomical structure homeostasis GO:0060249 145 0.106
visual perception GO:0007601 52 0.106
regulation of cell cycle GO:0051726 281 0.101
maintenance of protein location in nucleus GO:0051457 2 0.101
neural tube development GO:0021915 160 0.098
circulatory system process GO:0003013 197 0.098
germ cell development GO:0007281 185 0.097
regulation of cell projection organization GO:0031344 206 0.097
cellular response to hormone stimulus GO:0032870 150 0.096
muscle contraction GO:0006936 101 0.093
retina development in camera type eye GO:0060041 119 0.092
camera type eye development GO:0043010 266 0.092
embryonic epithelial tube formation GO:0001838 130 0.088
limbic system development GO:0021761 72 0.086
sensory perception of light stimulus GO:0050953 54 0.086
negative regulation of blood pressure GO:0045776 22 0.084
smooth muscle contraction GO:0006939 44 0.084
epithelial tube morphogenesis GO:0060562 303 0.082
multicellular organism growth GO:0035264 161 0.079
hippocampus development GO:0021766 52 0.079
negative regulation of systemic arterial blood pressure GO:0003085 15 0.078
epithelial tube formation GO:0072175 130 0.076
blood circulation GO:0008015 195 0.076
vasodilation GO:0042311 28 0.074
regulation of blood pressure GO:0008217 93 0.072
pigment metabolic process GO:0042440 32 0.072
male gamete generation GO:0048232 285 0.072
tube closure GO:0060606 91 0.071
intraciliary retrograde transport GO:0035721 3 0.069
Worm
tube formation GO:0035148 140 0.068
positive regulation of growth GO:0045927 104 0.064
regulation of cell motility GO:2000145 236 0.063
regulation of notch signaling pathway GO:0008593 35 0.062
positive regulation of cell projection organization GO:0031346 95 0.062
developmental pigmentation GO:0048066 40 0.060
regulation of blood vessel size GO:0050880 56 0.059
neural retina development GO:0003407 41 0.059
regulation of cellular component biogenesis GO:0044087 181 0.059
retina morphogenesis in camera type eye GO:0060042 45 0.058
response to nutrient levels GO:0031667 109 0.057
protein localization to nucleus GO:0034504 121 0.057
embryonic organ morphogenesis GO:0048562 276 0.057
regulation of cell projection assembly GO:0060491 38 0.055
muscle system process GO:0003012 141 0.054
regulation of tube size GO:0035150 57 0.052
response to extracellular stimulus GO:0009991 127 0.052
vascular process in circulatory system GO:0003018 62 0.050
vascular smooth muscle contraction GO:0014829 5 0.049
adult behavior GO:0030534 135 0.049
vasoconstriction GO:0042310 27 0.046
neural tube closure GO:0001843 90 0.046
tissue homeostasis GO:0001894 115 0.046
nucleoside phosphate metabolic process GO:0006753 338 0.044
mitotic cell cycle GO:0000278 195 0.044
positive regulation of organelle organization GO:0010638 128 0.043
determination of heart left right asymmetry GO:0061371 48 0.043
regulation of lipid metabolic process GO:0019216 118 0.042
mitotic cytokinesis GO:0000281 4 0.042
tonic smooth muscle contraction GO:0014820 3 0.042
developmental growth involved in morphogenesis GO:0060560 138 0.042
regulation of organelle organization GO:0033043 289 0.041
regulation of organelle assembly GO:1902115 19 0.041
microtubule based process GO:0007017 236 0.041
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
cellular amino acid metabolic process GO:0006520 103 0.038
embryonic heart tube development GO:0035050 65 0.038
regulation of cellular amine metabolic process GO:0033238 20 0.038
purine nucleotide metabolic process GO:0006163 302 0.037
response to leptin GO:0044321 7 0.037
maintenance of protein localization in organelle GO:0072595 2 0.037
protein localization to microtubule cytoskeleton GO:0072698 8 0.037
sensory perception of chemical stimulus GO:0007606 51 0.037
segmentation GO:0035282 93 0.037
artery smooth muscle contraction GO:0014824 2 0.036
ribonucleotide metabolic process GO:0009259 291 0.035
purine containing compound metabolic process GO:0072521 311 0.035
limb development GO:0060173 166 0.034
amine metabolic process GO:0009308 45 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
nucleotide metabolic process GO:0009117 332 0.032
embryonic heart tube morphogenesis GO:0003143 51 0.032
small gtpase mediated signal transduction GO:0007264 97 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.031
olfactory learning GO:0008355 2 0.031
morphogenesis of embryonic epithelium GO:0016331 159 0.031
regulation of cellular ketone metabolic process GO:0010565 66 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
maintenance of location GO:0051235 89 0.031
heart morphogenesis GO:0003007 178 0.030
heterocycle catabolic process GO:0046700 280 0.029
purine ribonucleotide metabolic process GO:0009150 290 0.029
somitogenesis GO:0001756 69 0.028
cellular ketone metabolic process GO:0042180 84 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
microtubule organizing center organization GO:0031023 28 0.027
cellular nitrogen compound catabolic process GO:0044270 280 0.027
microtubule based transport GO:0010970 50 0.026
Worm
organonitrogen compound catabolic process GO:1901565 264 0.026
protein catabolic process GO:0030163 221 0.025
ras protein signal transduction GO:0007265 77 0.025
axis elongation GO:0003401 30 0.025
purine nucleoside triphosphate metabolic process GO:0009144 226 0.025
organic cyclic compound catabolic process GO:1901361 295 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
protein localization to cytoskeleton GO:0044380 9 0.025
aromatic compound catabolic process GO:0019439 286 0.025
purine nucleoside metabolic process GO:0042278 241 0.024
sensory perception of sound GO:0007605 97 0.024
transmembrane transport GO:0055085 412 0.024
carbohydrate derivative catabolic process GO:1901136 231 0.024
maintenance of location in cell GO:0051651 24 0.024
cellular amine metabolic process GO:0044106 44 0.023
regulation of anatomical structure size GO:0090066 178 0.023
sensory perception of mechanical stimulus GO:0050954 107 0.023
nitrogen compound transport GO:0071705 271 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
cation transport GO:0006812 399 0.022
regulation of cellular catabolic process GO:0031329 242 0.022
membrane organization GO:0061024 245 0.022
somite development GO:0061053 81 0.022
cellular macromolecule catabolic process GO:0044265 206 0.021
embryonic limb morphogenesis GO:0030326 126 0.021
nucleoside metabolic process GO:0009116 246 0.021
limb morphogenesis GO:0035108 149 0.021
nucleoside catabolic process GO:0009164 206 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
cell adhesion GO:0007155 329 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
organophosphate catabolic process GO:0046434 232 0.020
centrosome organization GO:0051297 26 0.020
glycosyl compound catabolic process GO:1901658 206 0.020
nucleoside triphosphate metabolic process GO:0009141 230 0.020
purine containing compound catabolic process GO:0072523 213 0.020
protein ubiquitination GO:0016567 171 0.020
skin development GO:0043588 220 0.020
connective tissue development GO:0061448 179 0.019
response to acid chemical GO:0001101 111 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
neural tube formation GO:0001841 108 0.019
response to organonitrogen compound GO:0010243 246 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
nucleotide catabolic process GO:0009166 217 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
cellular protein catabolic process GO:0044257 155 0.018
multicellular organismal signaling GO:0035637 91 0.018
microtubule anchoring at centrosome GO:0034454 3 0.018
modification dependent protein catabolic process GO:0019941 133 0.018
positive regulation of protein modification process GO:0031401 299 0.018
glycosyl compound metabolic process GO:1901657 246 0.017
embryonic appendage morphogenesis GO:0035113 126 0.017
cytoplasmic transport GO:0016482 234 0.017
kidney development GO:0001822 213 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
macromolecule catabolic process GO:0009057 281 0.017
apoptotic signaling pathway GO:0097190 306 0.017
regulation of protein localization GO:0032880 231 0.017
regulation of neuron differentiation GO:0045664 281 0.017
appendage morphogenesis GO:0035107 149 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
cellular homeostasis GO:0019725 240 0.017
compound eye development GO:0048749 1 0.017
epidermis development GO:0008544 187 0.017
retinal rod cell development GO:0046548 10 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
retrograde transport endosome to golgi GO:0042147 2 0.016
anion transport GO:0006820 177 0.016
mitotic cell cycle process GO:1903047 159 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
guanosine containing compound catabolic process GO:1901069 144 0.016
rho protein signal transduction GO:0007266 32 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
intracellular protein transport GO:0006886 204 0.016
regulation of neuron projection development GO:0010975 169 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
regulation of systemic arterial blood pressure GO:0003073 61 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
regulation of intracellular transport GO:0032386 159 0.015
regulation of cell cycle process GO:0010564 160 0.015
response to radiation GO:0009314 165 0.015
transmission of nerve impulse GO:0019226 76 0.015
positive regulation of cellular component biogenesis GO:0044089 94 0.015
peptidyl amino acid modification GO:0018193 336 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
positive regulation of cell development GO:0010720 237 0.015
regulation of cell activation GO:0050865 289 0.015
striated muscle tissue development GO:0014706 293 0.015
cellular protein complex assembly GO:0043623 116 0.015
epithelial cell development GO:0002064 159 0.015
muscle cell differentiation GO:0042692 261 0.015
regulation of membrane potential GO:0042391 192 0.015
glucose homeostasis GO:0042593 128 0.015
cell fate commitment GO:0045165 210 0.015
retina layer formation GO:0010842 16 0.015
regulation of transferase activity GO:0051338 263 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
response to growth factor GO:0070848 198 0.014
microtubule anchoring GO:0034453 9 0.014
photoreceptor cell outer segment organization GO:0035845 5 0.014
regulation of hydrolase activity GO:0051336 246 0.014
regulation of protein kinase activity GO:0045859 232 0.014
renal system development GO:0072001 225 0.014
proteasomal protein catabolic process GO:0010498 98 0.014
muscle tissue development GO:0060537 308 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
cation transmembrane transport GO:0098655 266 0.014
positive regulation of nervous system development GO:0051962 221 0.014
maintenance of protein location in cell GO:0032507 20 0.014
positive regulation of neuron differentiation GO:0045666 141 0.014
gtp metabolic process GO:0046039 144 0.014
regulation of kinase activity GO:0043549 249 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
negative regulation of molecular function GO:0044092 258 0.014
regulation of proteolysis GO:0030162 164 0.014
immune effector process GO:0002252 321 0.013
respiratory tube development GO:0030323 167 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
gtp catabolic process GO:0006184 143 0.013
cytokinetic process GO:0032506 2 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
peptide transport GO:0015833 133 0.013
regulation of protein catabolic process GO:0042176 108 0.013
negative regulation of nervous system development GO:0051961 156 0.013
regulation of mapk cascade GO:0043408 248 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
oocyte axis specification GO:0007309 2 0.013
regulation of hormone levels GO:0010817 211 0.013
regulation of cell division GO:0051302 76 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
stem cell differentiation GO:0048863 268 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
protein localization to membrane GO:0072657 108 0.013
skeletal system morphogenesis GO:0048705 203 0.013
skeletal muscle organ development GO:0060538 163 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.013
action potential GO:0001508 78 0.013
asymmetric stem cell division GO:0098722 3 0.012
carbohydrate homeostasis GO:0033500 128 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
neuronal action potential GO:0019228 54 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
intraspecies interaction between organisms GO:0051703 21 0.012
gland development GO:0048732 330 0.012
convergent extension GO:0060026 14 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
carbohydrate metabolic process GO:0005975 230 0.012
actin filament organization GO:0007015 113 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
cartilage development GO:0051216 140 0.012
hormone secretion GO:0046879 128 0.012
negative regulation of immune system process GO:0002683 209 0.012
dna metabolic process GO:0006259 303 0.012
homeostasis of number of cells GO:0048872 210 0.012
oxidation reduction process GO:0055114 342 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
learning or memory GO:0007611 148 0.012
inflammatory response GO:0006954 244 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
detection of abiotic stimulus GO:0009582 60 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
regulation of homeostatic process GO:0032844 182 0.012
developmental maturation GO:0021700 193 0.012
carboxylic acid transport GO:0046942 100 0.012
regulation of protein transport GO:0051223 163 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
peptide hormone secretion GO:0030072 109 0.011
neuron apoptotic process GO:0051402 142 0.011
rhythmic process GO:0048511 174 0.011
organic anion transport GO:0015711 137 0.011
response to organic cyclic compound GO:0014070 198 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
lymphocyte differentiation GO:0030098 242 0.011
cell division GO:0051301 120 0.011
actin cytoskeleton organization GO:0030036 220 0.011
ossification GO:0001503 216 0.011
ion transmembrane transport GO:0034220 361 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
photoreceptor cell development GO:0042461 40 0.011
regulation of defense response GO:0031347 233 0.011
cellular chemical homeostasis GO:0055082 215 0.011
sequestering of calcium ion GO:0051208 18 0.011
positive regulation of protein catabolic process GO:0045732 60 0.011
mapk cascade GO:0000165 281 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
angiogenesis GO:0001525 201 0.011
cellular response to acid chemical GO:0071229 68 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
cellular lipid metabolic process GO:0044255 323 0.011
regulation of cell adhesion GO:0030155 154 0.011
cellular response to lipid GO:0071396 145 0.011
protein maturation GO:0051604 176 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
response to insulin GO:0032868 100 0.011
regulation of system process GO:0044057 200 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
neural precursor cell proliferation GO:0061351 121 0.010
cognition GO:0050890 149 0.010
rna interference GO:0016246 2 0.010
regulation of secretion GO:0051046 274 0.010
divalent inorganic cation transport GO:0072511 178 0.010
respiratory system development GO:0060541 190 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
positive regulation of cell death GO:0010942 224 0.010
inclusion body assembly GO:0070841 3 0.010
positive regulation of neuron projection development GO:0010976 79 0.010
regulation of neuron death GO:1901214 134 0.010
regulation of cytokinesis GO:0032465 5 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
maternal determination of anterior posterior axis embryo GO:0008358 2 0.010
regulation of intracellular protein transport GO:0033157 82 0.010
positive regulation of programmed cell death GO:0043068 218 0.010
purine nucleoside monophosphate metabolic process GO:0009126 81 0.010
regulation of cellular component size GO:0032535 121 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
negative regulation of protein modification process GO:0031400 163 0.010

Bbs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.054
nervous system disease DOID:863 0 0.054
central nervous system disease DOID:331 0 0.023
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
immune system disease DOID:2914 0 0.015
retinal disease DOID:5679 0 0.014
eye disease DOID:5614 0 0.014
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.013
brain disease DOID:936 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
bone disease DOID:0080001 0 0.011
disease of metabolism DOID:0014667 0 0.010
hematopoietic system disease DOID:74 0 0.010