Mus musculus

41 known processes

Bbs7

Bardet-Biedl syndrome 7 (human)

(Aliases: 8430406N16Rik)

Bbs7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
melanosome transport GO:0032402 11 0.297
establishment of melanosome localization GO:0032401 11 0.263
cilium morphogenesis GO:0060271 102 0.259
axoneme assembly GO:0035082 15 0.191
cilium assembly GO:0042384 81 0.172
nonmotile primary cilium assembly GO:0035058 8 0.122
spermatogenesis GO:0007283 284 0.116
cellular component assembly involved in morphogenesis GO:0010927 139 0.113
microtubule based movement GO:0007018 84 0.093
male gamete generation GO:0048232 285 0.093
organelle assembly GO:0070925 177 0.074
pigment granule localization GO:0051875 13 0.074
microtubule based transport GO:0010970 50 0.065
cellular response to cytokine stimulus GO:0071345 189 0.065
cellular amino acid metabolic process GO:0006520 103 0.063
cellular response to leptin stimulus GO:0044320 6 0.061
organelle localization GO:0051640 179 0.060
protein localization to organelle GO:0033365 185 0.058
spermatid differentiation GO:0048515 115 0.058
establishment of organelle localization GO:0051656 122 0.054
cellular ketone metabolic process GO:0042180 84 0.054
microtubule cytoskeleton organization GO:0000226 157 0.053
multicellular organismal homeostasis GO:0048871 164 0.053
cilium movement GO:0003341 28 0.051
amine metabolic process GO:0009308 45 0.050
spermatid development GO:0007286 108 0.050
regulation of cellular amino acid metabolic process GO:0006521 5 0.049
skeletal system development GO:0001501 356 0.048
cellular amine metabolic process GO:0044106 44 0.047
pigmentation GO:0043473 71 0.047
microtubule based process GO:0007017 236 0.047
regulation of cellular ketone metabolic process GO:0010565 66 0.046
fat cell differentiation GO:0045444 160 0.046
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
muscle system process GO:0003012 141 0.045
regulation of cilium movement GO:0003352 6 0.045
digestive system development GO:0055123 200 0.045
establishment of vesicle localization GO:0051650 81 0.045
pigment granule transport GO:0051904 12 0.045
muscle contraction GO:0006936 101 0.042
cellular response to hormone stimulus GO:0032870 150 0.042
organonitrogen compound catabolic process GO:1901565 264 0.041
forebrain development GO:0030900 302 0.041
organic cyclic compound catabolic process GO:1901361 295 0.041
regulation of microtubule based movement GO:0060632 8 0.041
regulation of cell motility GO:2000145 236 0.041
positive regulation of cellular amine metabolic process GO:0033240 5 0.040
regulation of organelle organization GO:0033043 289 0.040
regulation of cellular amine metabolic process GO:0033238 20 0.040
cellular lipid metabolic process GO:0044255 323 0.040
purine nucleoside triphosphate metabolic process GO:0009144 226 0.039
intraciliary retrograde transport GO:0035721 3 0.039
circulatory system process GO:0003013 197 0.038
blood circulation GO:0008015 195 0.038
regulation of cell cycle GO:0051726 281 0.038
smooth muscle contraction GO:0006939 44 0.038
nucleoside phosphate metabolic process GO:0006753 338 0.038
establishment of pigment granule localization GO:0051905 12 0.036
ras protein signal transduction GO:0007265 77 0.036
cellular nitrogen compound catabolic process GO:0044270 280 0.036
cytokine mediated signaling pathway GO:0019221 115 0.036
wnt signaling pathway GO:0016055 188 0.035
nucleotide metabolic process GO:0009117 332 0.035
regulation of cilium movement involved in cell motility GO:0060295 5 0.035
aromatic compound catabolic process GO:0019439 286 0.035
purine containing compound metabolic process GO:0072521 311 0.034
heterocycle catabolic process GO:0046700 280 0.034
nucleobase containing small molecule metabolic process GO:0055086 352 0.034
photoreceptor cell maintenance GO:0045494 19 0.034
organophosphate catabolic process GO:0046434 232 0.034
regulation of microtubule based process GO:0032886 52 0.033
transmembrane transport GO:0055085 412 0.033
adult behavior GO:0030534 135 0.033
purine nucleotide metabolic process GO:0006163 302 0.032
purine nucleoside metabolic process GO:0042278 241 0.032
tissue homeostasis GO:0001894 115 0.032
anatomical structure homeostasis GO:0060249 145 0.032
carbohydrate derivative catabolic process GO:1901136 231 0.032
gastrulation GO:0007369 116 0.032
determination of left right symmetry GO:0007368 80 0.031
regulation of anatomical structure size GO:0090066 178 0.031
nucleoside metabolic process GO:0009116 246 0.031
ribonucleoside metabolic process GO:0009119 245 0.031
eye photoreceptor cell differentiation GO:0001754 41 0.030
glycosyl compound metabolic process GO:1901657 246 0.030
sensory perception GO:0007600 245 0.030
small gtpase mediated signal transduction GO:0007264 97 0.030
vasodilation GO:0042311 28 0.030
purine ribonucleotide metabolic process GO:0009150 290 0.030
cytoskeleton dependent intracellular transport GO:0030705 50 0.030
intraciliary transport GO:0042073 9 0.029
vesicle localization GO:0051648 86 0.029
ribonucleotide metabolic process GO:0009259 291 0.029
nucleoside triphosphate metabolic process GO:0009141 230 0.028
appendage development GO:0048736 166 0.028
ribose phosphate metabolic process GO:0019693 291 0.028
cell adhesion GO:0007155 329 0.028
regionalization GO:0003002 337 0.027
regulation of cell projection organization GO:0031344 206 0.027
nucleotide catabolic process GO:0009166 217 0.027
ribonucleoside triphosphate catabolic process GO:0009203 199 0.027
purine nucleotide catabolic process GO:0006195 211 0.027
digestive tract morphogenesis GO:0048546 147 0.027
glycosyl compound catabolic process GO:1901658 206 0.026
multicellular organism growth GO:0035264 161 0.026
purine containing compound catabolic process GO:0072523 213 0.026
response to extracellular stimulus GO:0009991 127 0.026
pallium development GO:0021543 120 0.026
positive regulation of protein modification process GO:0031401 299 0.026
telencephalon development GO:0021537 186 0.026
cilium or flagellum dependent cell motility GO:0001539 6 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
digestive tract development GO:0048565 190 0.025
nucleoside triphosphate catabolic process GO:0009143 205 0.025
regulation of cellular component biogenesis GO:0044087 181 0.025
response to organonitrogen compound GO:0010243 246 0.024
response to nutrient levels GO:0031667 109 0.024
smoothened signaling pathway GO:0007224 105 0.024
regulation of cellular catabolic process GO:0031329 242 0.024
Human
camera type eye development GO:0043010 266 0.024
positive regulation of growth GO:0045927 104 0.024
olfactory learning GO:0008355 2 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
cation transport GO:0006812 399 0.024
negative regulation of growth GO:0045926 99 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
retina homeostasis GO:0001895 23 0.023
cellular macromolecule catabolic process GO:0044265 206 0.023
Human
regulation of cilium beat frequency involved in ciliary motility GO:0060296 5 0.023
cytoplasmic transport GO:0016482 234 0.023
hematopoietic progenitor cell differentiation GO:0002244 143 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
regulation of protein localization GO:0032880 231 0.023
leukocyte differentiation GO:0002521 342 0.023
mapk cascade GO:0000165 281 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.022
apoptotic signaling pathway GO:0097190 306 0.022
muscle cell differentiation GO:0042692 261 0.022
purine ribonucleoside metabolic process GO:0046128 241 0.022
lipid biosynthetic process GO:0008610 179 0.022
purine nucleoside catabolic process GO:0006152 205 0.022
dna metabolic process GO:0006259 303 0.022
oxidation reduction process GO:0055114 342 0.022
cerebral cortex development GO:0021987 86 0.022
epithelial tube formation GO:0072175 130 0.022
mitotic cell cycle GO:0000278 195 0.021
macromolecule catabolic process GO:0009057 281 0.021
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
regulation of membrane potential GO:0042391 192 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
peptidyl amino acid modification GO:0018193 336 0.021
ribonucleoside catabolic process GO:0042454 206 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.021
purine nucleoside triphosphate catabolic process GO:0009146 203 0.021
nitrogen compound transport GO:0071705 271 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
guanosine containing compound catabolic process GO:1901069 144 0.021
ion transmembrane transport GO:0034220 361 0.021
ribonucleotide catabolic process GO:0009261 208 0.020
regulation of hydrolase activity GO:0051336 246 0.020
connective tissue development GO:0061448 179 0.020
nucleoside catabolic process GO:0009164 206 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
cellular pigmentation GO:0033059 20 0.020
cellular homeostasis GO:0019725 240 0.020
regulation of blood vessel size GO:0050880 56 0.020
intracellular protein transport GO:0006886 204 0.020
striated muscle tissue development GO:0014706 293 0.020
vascular process in circulatory system GO:0003018 62 0.020
maintenance of location GO:0051235 89 0.020
skin development GO:0043588 220 0.020
tube formation GO:0035148 140 0.020
homeostasis of number of cells GO:0048872 210 0.019
immune effector process GO:0002252 321 0.019
cation transmembrane transport GO:0098655 266 0.019
limbic system development GO:0021761 72 0.019
hippocampus development GO:0021766 52 0.019
rho protein signal transduction GO:0007266 32 0.019
reactive oxygen species metabolic process GO:0072593 84 0.019
regulation of mapk cascade GO:0043408 248 0.019
cellular response to organonitrogen compound GO:0071417 145 0.019
regulation of transferase activity GO:0051338 263 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
primary neural tube formation GO:0014020 95 0.019
positive regulation of organelle organization GO:0010638 128 0.019
negative regulation of molecular function GO:0044092 258 0.019
neural tube development GO:0021915 160 0.019
inorganic ion transmembrane transport GO:0098660 234 0.018
regulation of tube size GO:0035150 57 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
embryonic epithelial tube formation GO:0001838 130 0.018
protein localization to nucleus GO:0034504 121 0.018
lymphocyte differentiation GO:0030098 242 0.018
gtp metabolic process GO:0046039 144 0.018
multicellular organismal signaling GO:0035637 91 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.018
regulation of kinase activity GO:0043549 249 0.018
cilium dependent cell motility GO:0060285 6 0.018
membrane organization GO:0061024 245 0.018
germ cell development GO:0007281 185 0.018
regulation of hormone levels GO:0010817 211 0.018
regulation of cell adhesion GO:0030155 154 0.017
stem cell differentiation GO:0048863 268 0.017
developmental growth involved in morphogenesis GO:0060560 138 0.017
regulation of cell activation GO:0050865 289 0.017
t cell activation GO:0042110 289 0.017
guanosine containing compound metabolic process GO:1901068 144 0.017
positive regulation of cell development GO:0010720 237 0.017
retina development in camera type eye GO:0060041 119 0.017
protein processing GO:0016485 163 0.017
cellular response to lipid GO:0071396 145 0.017
protein maturation GO:0051604 176 0.017
sensory organ morphogenesis GO:0090596 242 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
tube closure GO:0060606 91 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
g protein coupled receptor signaling pathway GO:0007186 243 0.017
regulation of homeostatic process GO:0032844 182 0.016
stem cell development GO:0048864 219 0.016
protein catabolic process GO:0030163 221 0.016
Human
cilium movement involved in cell motility GO:0060294 5 0.016
negative regulation of immune system process GO:0002683 209 0.016
regulation of protein kinase activity GO:0045859 232 0.016
protein targeting GO:0006605 143 0.016
organelle fission GO:0048285 170 0.016
eye photoreceptor cell development GO:0042462 31 0.016
muscle tissue development GO:0060537 308 0.016
positive regulation of hydrolase activity GO:0051345 148 0.016
notch signaling pathway GO:0007219 71 0.016
regulation of proteolysis GO:0030162 164 0.016
Human
myeloid cell differentiation GO:0030099 233 0.016
positive regulation of cell projection organization GO:0031346 95 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
cytokine production GO:0001816 319 0.016
methylation GO:0032259 134 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
response to food GO:0032094 17 0.016
dephosphorylation GO:0016311 129 0.016
cellular chemical homeostasis GO:0055082 215 0.016
transmission of nerve impulse GO:0019226 76 0.016
gtp catabolic process GO:0006184 143 0.016
regulation of neuron differentiation GO:0045664 281 0.015
response to lipopolysaccharide GO:0032496 128 0.015
b cell activation GO:0042113 161 0.015
regulation of secretion GO:0051046 274 0.015
melanosome localization GO:0032400 12 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
endomembrane system organization GO:0010256 147 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
regulation of cell projection assembly GO:0060491 38 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
chemotaxis GO:0006935 247 0.015
cell substrate adhesion GO:0031589 130 0.015
chromatin organization GO:0006325 206 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
positive regulation of nervous system development GO:0051962 221 0.015
cartilage development GO:0051216 140 0.015
sensory perception of chemical stimulus GO:0007606 51 0.014
lymphocyte proliferation GO:0046651 164 0.014
nuclear division GO:0000280 158 0.014
response to growth factor GO:0070848 198 0.014
t cell differentiation GO:0030217 174 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
regulation of response to food GO:0032095 10 0.014
cation homeostasis GO:0055080 212 0.014
nuclear transport GO:0051169 139 0.014
sequestering of calcium ion GO:0051208 18 0.014
regulation of lipid metabolic process GO:0019216 118 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
ossification GO:0001503 216 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
regulation of cytokine production GO:0001817 266 0.014
regulation of purine nucleotide catabolic process GO:0033121 122 0.014
inflammatory response GO:0006954 244 0.014
response to leptin GO:0044321 7 0.014
negative regulation of synapse assembly GO:0051964 3 0.014
response to inorganic substance GO:0010035 96 0.014
regulation of cell migration GO:0030334 219 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
cell type specific apoptotic process GO:0097285 268 0.013
regulation of gtp catabolic process GO:0033124 113 0.013
small molecule biosynthetic process GO:0044283 132 0.013
actin cytoskeleton organization GO:0030036 220 0.013
carbohydrate metabolic process GO:0005975 230 0.013
regulation of defense response GO:0031347 233 0.013
neuronal action potential GO:0019228 54 0.013
regulation of cytoskeleton organization GO:0051493 122 0.013
fertilization GO:0009566 127 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
urogenital system development GO:0001655 261 0.013
sequestering of metal ion GO:0051238 19 0.013
cellular protein catabolic process GO:0044257 155 0.013
Human
regulation of ion transport GO:0043269 215 0.013
response to acid chemical GO:0001101 111 0.013
axonogenesis GO:0007409 274 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.013
blood vessel morphogenesis GO:0048514 285 0.013
cellular ion homeostasis GO:0006873 165 0.013
response to oxidative stress GO:0006979 123 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
organic anion transport GO:0015711 137 0.013
leukocyte mediated immunity GO:0002443 174 0.013
positive regulation of cell death GO:0010942 224 0.013
action potential GO:0001508 78 0.013
epidermis development GO:0008544 187 0.013
innate immune response GO:0045087 157 0.013
response to organic cyclic compound GO:0014070 198 0.012
response to peptide hormone GO:0043434 127 0.012
divalent metal ion transport GO:0070838 172 0.012
regulation of t cell activation GO:0050863 170 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
regulation of secretion by cell GO:1903530 249 0.012
exocytosis GO:0006887 121 0.012
leukocyte activation involved in immune response GO:0002366 126 0.012
glucose homeostasis GO:0042593 128 0.012
regulation of intracellular transport GO:0032386 159 0.012
synaptic transmission GO:0007268 329 0.012
limb development GO:0060173 166 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
rna processing GO:0006396 105 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
epithelial cell development GO:0002064 159 0.012
kidney development GO:0001822 213 0.012
regulation of transmembrane transport GO:0034762 128 0.012
protein ubiquitination GO:0016567 171 0.012
anion transport GO:0006820 177 0.012
neural retina development GO:0003407 41 0.012
eye pigmentation GO:0048069 3 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
regulation of protein transport GO:0051223 163 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
compound eye development GO:0048749 1 0.012
hormone secretion GO:0046879 128 0.012
neural tube closure GO:0001843 90 0.012
regulation of response to wounding GO:1903034 189 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
positive regulation of mapk cascade GO:0043410 170 0.012
renal system development GO:0072001 225 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
Human
gland development GO:0048732 330 0.012
leukocyte proliferation GO:0070661 172 0.012
endocytosis GO:0006897 168 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
brain morphogenesis GO:0048854 32 0.012
single organism cell adhesion GO:0098602 156 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
cell activation involved in immune response GO:0002263 126 0.011
regulation of protein catabolic process GO:0042176 108 0.011
Human
negative regulation of phosphorylation GO:0042326 166 0.011
response to radiation GO:0009314 165 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
locomotory behavior GO:0007626 195 0.011
defense response to other organism GO:0098542 197 0.011
divalent inorganic cation transport GO:0072511 178 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
neural precursor cell proliferation GO:0061351 121 0.011
alcohol metabolic process GO:0006066 116 0.011
regulation of body fluid levels GO:0050878 162 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
leukocyte migration GO:0050900 124 0.011
regulation of actin filament based process GO:0032970 99 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
rhythmic process GO:0048511 174 0.011
positive regulation of transferase activity GO:0051347 167 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
metal ion homeostasis GO:0055065 189 0.011
hormone metabolic process GO:0042445 86 0.011
negative regulation of protein modification process GO:0031400 163 0.011
regulation of neuron projection development GO:0010975 169 0.011
macromolecule methylation GO:0043414 120 0.011
calcium ion transport GO:0006816 159 0.011
vasoconstriction GO:0042310 27 0.011
glycerolipid metabolic process GO:0046486 122 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
Human
peptide transport GO:0015833 133 0.011
carbohydrate homeostasis GO:0033500 128 0.011
protein localization to membrane GO:0072657 108 0.011
cognition GO:0050890 149 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
actin filament organization GO:0007015 113 0.011
negative regulation of nervous system development GO:0051961 156 0.011
cellular response to growth factor stimulus GO:0071363 197 0.010
establishment of protein localization to organelle GO:0072594 118 0.010
maintenance of protein location in nucleus GO:0051457 2 0.010
cellular protein complex assembly GO:0043623 116 0.010
striatum development GO:0021756 14 0.010
response to peptide GO:1901652 136 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
learning or memory GO:0007611 148 0.010
dna repair GO:0006281 107 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
response to light stimulus GO:0009416 135 0.010
meiotic cell cycle GO:0051321 122 0.010
cellular response to oxidative stress GO:0034599 76 0.010
cellular response to molecule of bacterial origin GO:0071219 83 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
carboxylic acid transport GO:0046942 100 0.010
positive regulation of nucleoside metabolic process GO:0045979 91 0.010
negative regulation of cell development GO:0010721 169 0.010
neuron death GO:0070997 154 0.010
regulation of cellular component size GO:0032535 121 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010

Bbs7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
musculoskeletal system disease DOID:17 0 0.016
central nervous system disease DOID:331 0 0.016
eye disease DOID:5614 0 0.016
retinal disease DOID:5679 0 0.012
disease of metabolism DOID:0014667 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011
neurodegenerative disease DOID:1289 0 0.010