Mus musculus

0 known processes

Polr3b

polymerase (RNA) III (DNA directed) polypeptide B

(Aliases: C85372,2700078H01Rik,A330032P03Rik,RPC2)

Polr3b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.077
cellular amino acid metabolic process GO:0006520 103 0.071
cellular amine metabolic process GO:0044106 44 0.050
amine metabolic process GO:0009308 45 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
regulation of cellular amino acid metabolic process GO:0006521 5 0.042
regulation of cellular amine metabolic process GO:0033238 20 0.041
dna repair GO:0006281 107 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.036
cellular response to dna damage stimulus GO:0006974 207 0.036
methylation GO:0032259 134 0.036
positive regulation of cellular amine metabolic process GO:0033240 5 0.035
cellular ketone metabolic process GO:0042180 84 0.035
macromolecule methylation GO:0043414 120 0.030
leukocyte differentiation GO:0002521 342 0.030
apoptotic signaling pathway GO:0097190 306 0.029
chromatin organization GO:0006325 206 0.028
regulation of organelle organization GO:0033043 289 0.027
histone modification GO:0016570 159 0.027
covalent chromatin modification GO:0016569 163 0.026
peptidyl amino acid modification GO:0018193 336 0.025
immune effector process GO:0002252 321 0.025
nuclear division GO:0000280 158 0.023
cation transmembrane transport GO:0098655 266 0.023
cellular nitrogen compound catabolic process GO:0044270 280 0.023
organelle fission GO:0048285 170 0.022
aromatic compound catabolic process GO:0019439 286 0.022
engulfment of apoptotic cell GO:0043652 3 0.020
protein localization to organelle GO:0033365 185 0.020
organelle assembly GO:0070925 177 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
cellular lipid metabolic process GO:0044255 323 0.020
ribonucleoside metabolic process GO:0009119 245 0.019
maintenance of location GO:0051235 89 0.019
heterocycle catabolic process GO:0046700 280 0.019
lymphocyte differentiation GO:0030098 242 0.019
cation transport GO:0006812 399 0.019
microtubule based process GO:0007017 236 0.018
oxidation reduction process GO:0055114 342 0.018
regulation of cell activation GO:0050865 289 0.018
transmembrane transport GO:0055085 412 0.018
regulation of intracellular transport GO:0032386 159 0.018
nucleoside phosphate metabolic process GO:0006753 338 0.018
nucleotide metabolic process GO:0009117 332 0.017
anatomical structure homeostasis GO:0060249 145 0.017
purine containing compound metabolic process GO:0072521 311 0.017
meiotic cell cycle process GO:1903046 77 0.017
nitrogen compound transport GO:0071705 271 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
multicellular organismal homeostasis GO:0048871 164 0.017
dna recombination GO:0006310 92 0.017
macromolecule catabolic process GO:0009057 281 0.017
intracellular protein transport GO:0006886 204 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
skeletal system development GO:0001501 356 0.016
action potential GO:0001508 78 0.016
cell type specific apoptotic process GO:0097285 268 0.016
myeloid cell differentiation GO:0030099 233 0.016
cellular response to lipid GO:0071396 145 0.016
response to organic cyclic compound GO:0014070 198 0.016
regulation of membrane potential GO:0042391 192 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
cytoplasmic transport GO:0016482 234 0.016
cytokine production GO:0001816 319 0.016
Human
purine nucleotide metabolic process GO:0006163 302 0.015
lipid biosynthetic process GO:0008610 179 0.015
purine ribonucleotide catabolic process GO:0009154 208 0.015
meiotic nuclear division GO:0007126 115 0.015
positive regulation of cell death GO:0010942 224 0.015
positive regulation of protein modification process GO:0031401 299 0.015
multicellular organismal signaling GO:0035637 91 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
b cell activation GO:0042113 161 0.015
endomembrane system organization GO:0010256 147 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
mitotic cell cycle GO:0000278 195 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
membrane organization GO:0061024 245 0.015
leukocyte activation involved in immune response GO:0002366 126 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
leukocyte mediated immunity GO:0002443 174 0.015
cellular macromolecule catabolic process GO:0044265 206 0.014
neuronal action potential GO:0019228 54 0.014
regulation of cell motility GO:2000145 236 0.014
chromatin modification GO:0016568 187 0.014
muscle tissue development GO:0060537 308 0.014
ion transmembrane transport GO:0034220 361 0.014
striated muscle tissue development GO:0014706 293 0.014
rna processing GO:0006396 105 0.014
blastocyst development GO:0001824 80 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
nuclear transport GO:0051169 139 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
lateral inhibition GO:0046331 1 0.014
protein localization to nucleus GO:0034504 121 0.014
cell adhesion GO:0007155 329 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
regulation of protein localization GO:0032880 231 0.014
transmission of nerve impulse GO:0019226 76 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
muscle cell differentiation GO:0042692 261 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
blood circulation GO:0008015 195 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
cell activation involved in immune response GO:0002263 126 0.013
organophosphate catabolic process GO:0046434 232 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
ossification GO:0001503 216 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
regulation of cytokine production GO:0001817 266 0.013
Human
glycosyl compound metabolic process GO:1901657 246 0.013
small molecule biosynthetic process GO:0044283 132 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
purine containing compound catabolic process GO:0072523 213 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
cell division GO:0051301 120 0.013
production of molecular mediator of immune response GO:0002440 103 0.013
positive regulation of cell activation GO:0050867 158 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
protein processing GO:0016485 163 0.013
meiotic cell cycle GO:0051321 122 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
circulatory system process GO:0003013 197 0.013
cellular homeostasis GO:0019725 240 0.013
protein catabolic process GO:0030163 221 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
response to lipopolysaccharide GO:0032496 128 0.012
cellular chemical homeostasis GO:0055082 215 0.012
wnt signaling pathway GO:0016055 188 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
regulation of defense response GO:0031347 233 0.012
Human
nucleotide catabolic process GO:0009166 217 0.012
negative regulation of immune system process GO:0002683 209 0.012
t cell activation GO:0042110 289 0.012
alcohol metabolic process GO:0006066 116 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
response to oxidative stress GO:0006979 123 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
glycerolipid metabolic process GO:0046486 122 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
carbohydrate metabolic process GO:0005975 230 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
response to inorganic substance GO:0010035 96 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
spermatogenesis GO:0007283 284 0.012
organelle localization GO:0051640 179 0.012
neuron apoptotic process GO:0051402 142 0.012
ras protein signal transduction GO:0007265 77 0.012
divalent inorganic cation transport GO:0072511 178 0.012
response to radiation GO:0009314 165 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
regulation of transferase activity GO:0051338 263 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
protein maturation GO:0051604 176 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
mapk cascade GO:0000165 281 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
positive regulation of apoptotic process GO:0043065 217 0.011
cation homeostasis GO:0055080 212 0.011
nucleoside catabolic process GO:0009164 206 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.011
sensory perception GO:0007600 245 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
response to acid chemical GO:0001101 111 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
regulation of system process GO:0044057 200 0.011
negative regulation of molecular function GO:0044092 258 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
regulation of homeostatic process GO:0032844 182 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
peptidyl lysine modification GO:0018205 77 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
skeletal muscle organ development GO:0060538 163 0.011
neuron death GO:0070997 154 0.011
nuclear import GO:0051170 95 0.011
regulation of secretion by cell GO:1903530 249 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.011
protein targeting GO:0006605 143 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
regulation of chromosome organization GO:0033044 83 0.011
histone lysine methylation GO:0034968 50 0.011
forebrain development GO:0030900 302 0.011
regulation of protein transport GO:0051223 163 0.011
compound eye development GO:0048749 1 0.011
regulation of cell cycle GO:0051726 281 0.011
stem cell differentiation GO:0048863 268 0.011
respiratory system development GO:0060541 190 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
positive regulation of cytokine production GO:0001819 174 0.010
Human
tissue homeostasis GO:0001894 115 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.010
protein modification by small protein conjugation GO:0032446 187 0.010
germ cell development GO:0007281 185 0.010
regulation of hormone levels GO:0010817 211 0.010
regulation of kinase activity GO:0043549 249 0.010
regulation of cell migration GO:0030334 219 0.010
glycoprotein metabolic process GO:0009100 116 0.010
nucleoside metabolic process GO:0009116 246 0.010
regulation of secretion GO:0051046 274 0.010
glycerophospholipid metabolic process GO:0006650 71 0.010
chromosome segregation GO:0007059 48 0.010
nucleus organization GO:0006997 45 0.010
endocytosis GO:0006897 168 0.010
negative regulation of dna replication GO:0008156 4 0.010
regulation of anatomical structure size GO:0090066 178 0.010
cell fate commitment GO:0045165 210 0.010
dephosphorylation GO:0016311 129 0.010
positive regulation of immune effector process GO:0002699 107 0.010
regulation of mapk cascade GO:0043408 248 0.010
response to molecule of bacterial origin GO:0002237 143 0.010
regulation of cytoplasmic transport GO:1903649 112 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.010
mrna metabolic process GO:0016071 84 0.010
protein ubiquitination GO:0016567 171 0.010
response to organonitrogen compound GO:0010243 246 0.010
phospholipid metabolic process GO:0006644 87 0.010
respiratory tube development GO:0030323 167 0.010
response to extracellular stimulus GO:0009991 127 0.010
digestive system development GO:0055123 200 0.010
regulation of hydrolase activity GO:0051336 246 0.010

Polr3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.018
disease of anatomical entity DOID:7 0 0.018
sensory system disease DOID:0050155 0 0.018
eye and adnexa disease DOID:1492 0 0.017
retinal disease DOID:5679 0 0.016
retinal degeneration DOID:8466 0 0.016
eye disease DOID:5614 0 0.016
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012