Mus musculus

0 known processes

Fpgs

folylpolyglutamyl synthetase

(Aliases: AA408187)

Fpgs biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vitamin transmembrane transport GO:0035461 4 0.166
cellular amino acid metabolic process GO:0006520 103 0.135
transmembrane transport GO:0055085 412 0.076
dna metabolic process GO:0006259 303 0.075
nitrogen compound transport GO:0071705 271 0.074
cellular response to dna damage stimulus GO:0006974 207 0.066
ion transmembrane transport GO:0034220 361 0.065
cellular amine metabolic process GO:0044106 44 0.064
organonitrogen compound biosynthetic process GO:1901566 192 0.063
organonitrogen compound catabolic process GO:1901565 264 0.061
cellular ketone metabolic process GO:0042180 84 0.059
serine family amino acid metabolic process GO:0009069 7 0.059
nucleobase containing small molecule metabolic process GO:0055086 352 0.058
purine containing compound metabolic process GO:0072521 311 0.053
organic cyclic compound catabolic process GO:1901361 295 0.051
cation transport GO:0006812 399 0.051
positive regulation of cellular amine metabolic process GO:0033240 5 0.048
purine nucleoside metabolic process GO:0042278 241 0.048
ras protein signal transduction GO:0007265 77 0.047
myeloid cell differentiation GO:0030099 233 0.046
l serine metabolic process GO:0006563 2 0.046
regulation of cell cycle GO:0051726 281 0.046
regulation of cellular ketone metabolic process GO:0010565 66 0.044
regulation of organelle organization GO:0033043 289 0.044
apoptotic signaling pathway GO:0097190 306 0.043
cellular nitrogen compound catabolic process GO:0044270 280 0.041
positive regulation of cell death GO:0010942 224 0.041
amine metabolic process GO:0009308 45 0.040
oxidation reduction process GO:0055114 342 0.040
purine nucleotide catabolic process GO:0006195 211 0.039
cation transmembrane transport GO:0098655 266 0.038
purine nucleoside triphosphate catabolic process GO:0009146 203 0.037
alpha amino acid metabolic process GO:1901605 59 0.036
ribonucleoside metabolic process GO:0009119 245 0.036
purine nucleoside catabolic process GO:0006152 205 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
regulation of hydrolase activity GO:0051336 246 0.036
aromatic compound catabolic process GO:0019439 286 0.035
cellular homeostasis GO:0019725 240 0.035
alpha amino acid biosynthetic process GO:1901607 15 0.035
nucleoside phosphate metabolic process GO:0006753 338 0.034
organic anion transport GO:0015711 137 0.034
carbohydrate derivative biosynthetic process GO:1901137 183 0.033
inorganic ion transmembrane transport GO:0098660 234 0.033
nucleoside metabolic process GO:0009116 246 0.033
positive regulation of programmed cell death GO:0043068 218 0.032
positive regulation of apoptotic process GO:0043065 217 0.032
carbohydrate metabolic process GO:0005975 230 0.030
cation homeostasis GO:0055080 212 0.030
nucleoside catabolic process GO:0009164 206 0.030
purine nucleotide metabolic process GO:0006163 302 0.030
glycosyl compound metabolic process GO:1901657 246 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.029
folic acid containing compound metabolic process GO:0006760 3 0.029
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
small gtpase mediated signal transduction GO:0007264 97 0.028
protein processing GO:0016485 163 0.028
purine ribonucleotide catabolic process GO:0009154 208 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.028
anion transport GO:0006820 177 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.027
regulation of membrane potential GO:0042391 192 0.027
negative regulation of protein metabolic process GO:0051248 282 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
innate immune response GO:0045087 157 0.026
regulation of binding GO:0051098 111 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.025
thiamine transport GO:0015888 2 0.025
intracellular protein transport GO:0006886 204 0.025
macromolecule catabolic process GO:0009057 281 0.025
cellular response to cytokine stimulus GO:0071345 189 0.024
organic acid biosynthetic process GO:0016053 86 0.024
purine nucleoside triphosphate metabolic process GO:0009144 226 0.024
homeostasis of number of cells GO:0048872 210 0.024
regulation of proteolysis GO:0030162 164 0.024
protein maturation GO:0051604 176 0.023
membrane organization GO:0061024 245 0.023
nucleoside triphosphate metabolic process GO:0009141 230 0.023
nucleotide metabolic process GO:0009117 332 0.023
leukocyte differentiation GO:0002521 342 0.023
glycosyl compound catabolic process GO:1901658 206 0.023
purine ribonucleotide metabolic process GO:0009150 290 0.023
regulation of purine nucleotide metabolic process GO:1900542 169 0.023
regulation of cell cycle process GO:0010564 160 0.023
regulation of apoptotic signaling pathway GO:2001233 197 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.022
immune effector process GO:0002252 321 0.022
sulfur compound transport GO:0072348 9 0.022
cellular chemical homeostasis GO:0055082 215 0.022
engulfment of apoptotic cell GO:0043652 3 0.021
regulation of nucleotide metabolic process GO:0006140 169 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
purine containing compound catabolic process GO:0072523 213 0.021
small molecule biosynthetic process GO:0044283 132 0.021
protein targeting GO:0006605 143 0.021
respiratory system development GO:0060541 190 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
metal ion homeostasis GO:0055065 189 0.020
nucleotide catabolic process GO:0009166 217 0.020
guanosine containing compound catabolic process GO:1901069 144 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
epidermis development GO:0008544 187 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
negative regulation of cell cycle GO:0045786 123 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.020
muscle tissue development GO:0060537 308 0.020
skin development GO:0043588 220 0.020
mitotic cell cycle GO:0000278 195 0.019
regulation of transferase activity GO:0051338 263 0.019
hexose metabolic process GO:0019318 98 0.019
regulation of defense response GO:0031347 233 0.019
negative regulation of cellular component organization GO:0051129 194 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
maintenance of location GO:0051235 89 0.019
rna processing GO:0006396 105 0.019
dna repair GO:0006281 107 0.019
peptidyl amino acid modification GO:0018193 336 0.019
ossification GO:0001503 216 0.019
anion transmembrane transport GO:0098656 71 0.019
regulation of cysteine type endopeptidase activity GO:2000116 65 0.019
ribonucleoside catabolic process GO:0042454 206 0.018
glycoprotein biosynthetic process GO:0009101 89 0.018
regulation of ion transport GO:0043269 215 0.018
compound eye development GO:0048749 1 0.018
male gamete generation GO:0048232 285 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
regulation of cellular amino acid metabolic process GO:0006521 5 0.018
regulation of anatomical structure size GO:0090066 178 0.018
protein ubiquitination GO:0016567 171 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.018
cellular amino acid biosynthetic process GO:0008652 22 0.018
macromolecule glycosylation GO:0043413 55 0.018
multicellular organism growth GO:0035264 161 0.017
notch signaling pathway GO:0007219 71 0.017
macromolecule methylation GO:0043414 120 0.017
developmental maturation GO:0021700 193 0.017
protein catabolic process GO:0030163 221 0.017
leukocyte proliferation GO:0070661 172 0.017
glycosylation GO:0070085 62 0.017
regulation of peptidase activity GO:0052547 96 0.017
regulation of endopeptidase activity GO:0052548 89 0.017
regulation of gtp catabolic process GO:0033124 113 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
organophosphate catabolic process GO:0046434 232 0.017
regulation of actin filament based process GO:0032970 99 0.017
regulation of mitotic cell cycle GO:0007346 126 0.016
regulation of homeostatic process GO:0032844 182 0.016
negative regulation of molecular function GO:0044092 258 0.016
negative regulation of protein modification process GO:0031400 163 0.016
exocytosis GO:0006887 121 0.016
locomotory behavior GO:0007626 195 0.016
regulation of protein kinase activity GO:0045859 232 0.016
glycoprotein metabolic process GO:0009100 116 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
regulation of body fluid levels GO:0050878 162 0.016
cytokine production GO:0001816 319 0.016
organic acid transport GO:0015849 101 0.016
fat cell differentiation GO:0045444 160 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
dna endoreduplication GO:0042023 4 0.016
cell adhesion GO:0007155 329 0.016
modification dependent protein catabolic process GO:0019941 133 0.016
response to organic cyclic compound GO:0014070 198 0.016
regulation of cytokine production GO:0001817 266 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
regulation of intracellular transport GO:0032386 159 0.015
amino acid transport GO:0006865 61 0.015
regulation of transmembrane transport GO:0034762 128 0.015
mitotic cell cycle process GO:1903047 159 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
cytoplasmic transport GO:0016482 234 0.015
rho protein signal transduction GO:0007266 32 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
germ cell development GO:0007281 185 0.015
multicellular organismal signaling GO:0035637 91 0.015
positive regulation of proteolysis GO:0045862 85 0.015
vitamin transport GO:0051180 10 0.015
regulation of nucleoside metabolic process GO:0009118 130 0.015
regulation of lymphocyte proliferation GO:0050670 117 0.015
methylation GO:0032259 134 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
oocyte axis specification GO:0007309 2 0.015
positive regulation of hydrolase activity GO:0051345 148 0.014
sensory perception GO:0007600 245 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
mitochondrion organization GO:0007005 134 0.014
positive regulation of apoptotic signaling pathway GO:2001235 95 0.014
regulation of cell activation GO:0050865 289 0.014
guanosine containing compound metabolic process GO:1901068 144 0.014
heterocycle catabolic process GO:0046700 280 0.014
hormone secretion GO:0046879 128 0.014
carbohydrate homeostasis GO:0033500 128 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
peptide transport GO:0015833 133 0.014
glucose homeostasis GO:0042593 128 0.014
retrograde transport endosome to golgi GO:0042147 2 0.014
peptidyl tyrosine phosphorylation GO:0018108 143 0.014
regulation of kinase activity GO:0043549 249 0.014
cellular amino acid catabolic process GO:0009063 25 0.014
cellular ion homeostasis GO:0006873 165 0.014
organelle assembly GO:0070925 177 0.014
response to radiation GO:0009314 165 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
respiratory tube development GO:0030323 167 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
proteasomal protein catabolic process GO:0010498 98 0.014
lymphocyte proliferation GO:0046651 164 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
single organism cell adhesion GO:0098602 156 0.013
mapk cascade GO:0000165 281 0.013
fertilization GO:0009566 127 0.013
stem cell differentiation GO:0048863 268 0.013
purine nucleobase biosynthetic process GO:0009113 3 0.013
forebrain development GO:0030900 302 0.013
pyrimidine containing compound transmembrane transport GO:0072531 5 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
striated muscle tissue development GO:0014706 293 0.013
cellular component assembly involved in morphogenesis GO:0010927 139 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
amide transport GO:0042886 138 0.013
regulation of protein processing GO:0070613 96 0.013
skeletal system development GO:0001501 356 0.013
blood circulation GO:0008015 195 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
neuronal action potential GO:0019228 54 0.013
response to light stimulus GO:0009416 135 0.013
lipid biosynthetic process GO:0008610 179 0.013
protein glycosylation GO:0006486 55 0.013
regulation of adaptive immune response GO:0002819 90 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
adaptive immune response GO:0002250 155 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
extracellular matrix organization GO:0030198 147 0.013
spinal cord development GO:0021510 81 0.013
carboxylic acid transport GO:0046942 100 0.013
extracellular structure organization GO:0043062 148 0.013
mrna metabolic process GO:0016071 84 0.013
lung development GO:0030324 164 0.013
cell maturation GO:0048469 127 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
inflammatory response GO:0006954 244 0.013
nuclear transport GO:0051169 139 0.012
organelle fission GO:0048285 170 0.012
actin cytoskeleton organization GO:0030036 220 0.012
epithelial cell proliferation GO:0050673 174 0.012
spermatogenesis GO:0007283 284 0.012
cofactor metabolic process GO:0051186 80 0.012
meiotic nuclear division GO:0007126 115 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
muscle system process GO:0003012 141 0.012
drug transmembrane transport GO:0006855 5 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
development of primary sexual characteristics GO:0045137 143 0.012
lymphocyte differentiation GO:0030098 242 0.012
purine nucleobase metabolic process GO:0006144 4 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
response to inorganic substance GO:0010035 96 0.012
cellular response to lipid GO:0071396 145 0.012
urogenital system development GO:0001655 261 0.012
regulation of cellular response to stress GO:0080135 159 0.012
gtp metabolic process GO:0046039 144 0.012
molting cycle GO:0042303 90 0.012
nucleobase biosynthetic process GO:0046112 3 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
g1 s transition of mitotic cell cycle GO:0000082 57 0.012
negative regulation of organelle organization GO:0010639 90 0.012
positive regulation of kinase activity GO:0033674 155 0.012
response to oxidative stress GO:0006979 123 0.012
negative regulation of nervous system development GO:0051961 156 0.012
negative regulation of immune system process GO:0002683 209 0.012
glial cell differentiation GO:0010001 131 0.012
telencephalon development GO:0021537 186 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
myeloid cell homeostasis GO:0002262 114 0.012
cellularization GO:0007349 1 0.011
kidney development GO:0001822 213 0.011
protein import GO:0017038 101 0.011
apoptotic mitochondrial changes GO:0008637 48 0.011
t cell activation GO:0042110 289 0.011
steroid metabolic process GO:0008202 119 0.011
regulation of cell size GO:0008361 72 0.011
l amino acid transport GO:0015807 32 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001267 4 0.011
positive regulation of cell cycle GO:0045787 92 0.011
blood vessel morphogenesis GO:0048514 285 0.011
regulation of translation GO:0006417 71 0.011
rhythmic process GO:0048511 174 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
regulation of secretion GO:0051046 274 0.011
segmentation GO:0035282 93 0.011
nucleotide transmembrane transport GO:1901679 2 0.011
positive regulation of cell cycle process GO:0090068 61 0.011
anatomical structure homeostasis GO:0060249 145 0.011
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
regulation of hormone levels GO:0010817 211 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
negative regulation of protein processing GO:0010955 79 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
monosaccharide metabolic process GO:0005996 106 0.011
regulation of mapk cascade GO:0043408 248 0.011
regulation of nucleocytoplasmic transport GO:0046822 73 0.011
odontogenesis GO:0042476 78 0.011
interleukin 8 production GO:0032637 4 0.011
divalent metal ion transport GO:0070838 172 0.011
osteoclast differentiation GO:0030316 62 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
muscle cell differentiation GO:0042692 261 0.011
sensory system development GO:0048880 3 0.011
peptide hormone secretion GO:0030072 109 0.011
peptide secretion GO:0002790 114 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
regulation of t cell proliferation GO:0042129 92 0.011
nucleoside transmembrane transport GO:1901642 4 0.011
regulation of cell migration GO:0030334 219 0.010
sulfur compound biosynthetic process GO:0044272 37 0.010
positive regulation of cellular catabolic process GO:0031331 148 0.010
progesterone metabolic process GO:0042448 4 0.010
response to molecule of bacterial origin GO:0002237 143 0.010
calcium ion transport GO:0006816 159 0.010
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.010
erythrocyte differentiation GO:0030218 88 0.010
pigment biosynthetic process GO:0046148 26 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.010
stem cell development GO:0048864 219 0.010
cell division GO:0051301 120 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.010
oocyte construction GO:0007308 2 0.010
cellular alcohol biosynthetic process GO:0044108 3 0.010
meiotic cell cycle GO:0051321 122 0.010
myeloid leukocyte differentiation GO:0002573 119 0.010
regionalization GO:0003002 337 0.010
insulin secretion GO:0030073 89 0.010
amino acid transmembrane transport GO:0003333 37 0.010
pigment metabolic process GO:0042440 32 0.010
digestive tract development GO:0048565 190 0.010
action potential GO:0001508 78 0.010
circulatory system process GO:0003013 197 0.010

Fpgs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.029
inherited metabolic disorder DOID:655 0 0.029
immune system disease DOID:2914 0 0.024
disease of anatomical entity DOID:7 0 0.024
hematopoietic system disease DOID:74 0 0.021
nervous system disease DOID:863 0 0.019
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015
bone development disease DOID:0080006 0 0.013
bone disease DOID:0080001 0 0.013
anemia DOID:2355 0 0.013
amino acid metabolic disorder DOID:9252 0 0.011