|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
1.000
|
Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.999
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.996
|
Mouse |
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.995
|
Mouse |
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.991
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.989
|
Mouse |
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.988
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.984
|
Mouse |
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.975
|
Mouse |
|
|
positive thymic t cell selection
|
GO:0045059 |
13 |
0.973
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.972
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.969
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.968
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.965
|
Mouse |
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.961
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.957
|
Mouse |
|
|
negative regulation of t cell mediated cytotoxicity
|
GO:0001915 |
3 |
0.956
|
|
|
|
neutrophil activation
|
GO:0042119 |
9 |
0.955
|
Mouse |
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.952
|
Mouse |
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
4 |
0.951
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.949
|
|
|
|
gamma delta t cell differentiation
|
GO:0042492 |
11 |
0.945
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.933
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.931
|
Mouse |
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.929
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.912
|
Mouse |
|
|
platelet degranulation
|
GO:0002576 |
6 |
0.909
|
Mouse |
|
|
positive regulation of t cell mediated cytotoxicity
|
GO:0001916 |
15 |
0.894
|
|
|
|
cd4 positive cd25 positive alpha beta regulatory t cell differentiation
|
GO:0002361 |
4 |
0.894
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.869
|
Mouse |
|
|
serotonin production involved in inflammatory response
|
GO:0002351 |
4 |
0.867
|
Mouse |
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.862
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.858
|
|
|
|
neutrophil activation involved in immune response
|
GO:0002283 |
8 |
0.854
|
Mouse |
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.853
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.852
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.852
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
27 |
0.836
|
Mouse |
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.832
|
Mouse |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.831
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.826
|
|
|
|
fc receptor mediated stimulatory signaling pathway
|
GO:0002431 |
4 |
0.826
|
Mouse |
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.808
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.806
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.797
|
Mouse |
|
|
regulation of t cell mediated cytotoxicity
|
GO:0001914 |
18 |
0.792
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
25 |
0.789
|
Mouse |
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.784
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.764
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.757
|
Mouse |
|
|
cation transport
|
GO:0006812 |
399 |
0.754
|
Mouse |
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.750
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.720
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.718
|
Mouse |
|
|
negative regulation of t cell mediated immunity
|
GO:0002710 |
9 |
0.717
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.708
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.703
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.685
|
|
|
|
gamma delta t cell activation
|
GO:0046629 |
13 |
0.684
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.679
|
Mouse |
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.670
|
Mouse |
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.664
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.663
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.657
|
Mouse |
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.656
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.629
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.624
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.619
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.611
|
|
|
|
lymph node development
|
GO:0048535 |
18 |
0.592
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.583
|
Mouse |
|
|
positive regulation of b cell differentiation
|
GO:0045579 |
13 |
0.572
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.572
|
|
|
|
t cell mediated cytotoxicity
|
GO:0001913 |
26 |
0.571
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.570
|
Mouse |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.559
|
Mouse |
|
|
granulocyte activation
|
GO:0036230 |
10 |
0.554
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.542
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.531
|
|
|
|
negative t cell selection
|
GO:0043383 |
13 |
0.530
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.522
|
Mouse |
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.522
|
|
|
|
positive regulation of podosome assembly
|
GO:0071803 |
3 |
0.516
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.510
|
|
|
|
positive regulation of mast cell activation involved in immune response
|
GO:0033008 |
10 |
0.506
|
Mouse |
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
20 |
0.503
|
Mouse |
|
|
regulation of gamma delta t cell activation
|
GO:0046643 |
9 |
0.502
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.498
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.498
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.497
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.495
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.486
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.485
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.485
|
Mouse |
|
|
exocytosis
|
GO:0006887 |
121 |
0.477
|
Mouse |
|
|
muscle contraction
|
GO:0006936 |
101 |
0.474
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.473
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.471
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.458
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.457
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.450
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.450
|
|
|
|
regulation of podosome assembly
|
GO:0071801 |
3 |
0.450
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.448
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.447
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.443
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.442
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.442
|
|
|
|
positive regulation of leukocyte degranulation
|
GO:0043302 |
10 |
0.441
|
Mouse |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.439
|
Mouse |
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.434
|
|
|
|
cellular zinc ion homeostasis
|
GO:0006882 |
9 |
0.434
|
|
|
|
regulation of smooth muscle contraction
|
GO:0006940 |
22 |
0.424
|
|
|
|
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway
|
GO:0010579 |
3 |
0.421
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.419
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.419
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.416
|
|
|
|
positive regulation of muscle contraction
|
GO:0045933 |
10 |
0.414
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.409
|
|
|
|
immune response inhibiting signal transduction
|
GO:0002765 |
4 |
0.404
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.401
|
|
|
|
regulation of type iia hypersensitivity
|
GO:0001796 |
4 |
0.400
|
Mouse |
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.396
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.396
|
|
|
|
positive regulation of b cell receptor signaling pathway
|
GO:0050861 |
4 |
0.393
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.391
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.388
|
|
|
|
positive regulation of mast cell activation
|
GO:0033005 |
12 |
0.383
|
Mouse |
|
|
interleukin 4 production
|
GO:0032633 |
24 |
0.382
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.379
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.377
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.377
|
|
|
|
monoamine transport
|
GO:0015844 |
33 |
0.375
|
Mouse |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.369
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.369
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.369
|
Mouse |
|
|
activation of phospholipase c activity
|
GO:0007202 |
2 |
0.366
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.365
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.363
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.357
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.357
|
Mouse |
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.355
|
|
|
|
regulation of t cell anergy
|
GO:0002667 |
4 |
0.350
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.349
|
Mouse |
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.348
|
Mouse |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.348
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.340
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.337
|
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
3 |
0.337
|
|
|
|
regulation of t cell differentiation in thymus
|
GO:0033081 |
24 |
0.334
|
|
|
|
positive regulation of type iii hypersensitivity
|
GO:0001805 |
3 |
0.333
|
Mouse |
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
3 |
0.324
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
28 |
0.324
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.317
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.317
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.309
|
|
|
|
negative regulation of cell adhesion involved in substrate bound cell migration
|
GO:0006933 |
3 |
0.307
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.303
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.301
|
|
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
0.297
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.291
|
Mouse |
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.290
|
Mouse |
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
3 |
0.287
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.287
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.287
|
Mouse |
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.284
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.277
|
|
|
|
positive regulation of gamma delta t cell activation
|
GO:0046645 |
6 |
0.276
|
|
|
|
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045425 |
2 |
0.270
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.265
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.262
|
|
|
|
positive regulation of calcium mediated signaling
|
GO:0050850 |
15 |
0.258
|
|
|
|
neutrophil mediated immunity
|
GO:0002446 |
19 |
0.253
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.253
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.250
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.247
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.246
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.245
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.245
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.234
|
|
|
|
fc epsilon receptor signaling pathway
|
GO:0038095 |
3 |
0.230
|
Mouse |
|
|
organelle localization
|
GO:0051640 |
179 |
0.230
|
Mouse |
|
|
lipid transport
|
GO:0006869 |
98 |
0.228
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.227
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.226
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.226
|
|
|
|
regulation of lymphocyte anergy
|
GO:0002911 |
4 |
0.226
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.225
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.224
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.223
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.221
|
|
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
8 |
0.220
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.219
|
|
|
|
somatotropin secreting cell differentiation
|
GO:0060126 |
4 |
0.218
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.217
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.216
|
Mouse |
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.214
|
|
|
|
serotonin transport
|
GO:0006837 |
11 |
0.213
|
Mouse |
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.212
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.209
|
Mouse |
|
|
immune effector process
|
GO:0002252 |
321 |
0.206
|
Mouse |
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.204
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.202
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.197
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.195
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.194
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.189
|
|
|
|
negative regulation of toll like receptor 2 signaling pathway
|
GO:0034136 |
3 |
0.187
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.184
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
13 |
0.184
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.179
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.179
|
|
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
1 |
0.178
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.178
|
Mouse |
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.177
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.177
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.176
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.175
|
|
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
18 |
0.174
|
|
|
|
g protein coupled receptor internalization
|
GO:0002031 |
3 |
0.174
|
|
|
|
regulation of hematopoietic stem cell migration
|
GO:2000471 |
1 |
0.171
|
|
|
|
general adaptation syndrome
|
GO:0051866 |
2 |
0.170
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.169
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.168
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.166
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.165
|
Mouse |
|
|
developmental maturation
|
GO:0021700 |
193 |
0.165
|
|
|
|
nk t cell differentiation
|
GO:0001865 |
8 |
0.164
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
19 |
0.162
|
|
|
|
production of molecular mediator involved in inflammatory response
|
GO:0002532 |
21 |
0.160
|
Mouse |
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.157
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.156
|
Mouse |
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
24 |
0.156
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.155
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.155
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.154
|
|
|
|
branching involved in labyrinthine layer morphogenesis
|
GO:0060670 |
9 |
0.154
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
12 |
0.153
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.153
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.150
|
|
|
|
detection of mechanical stimulus involved in sensory perception of pain
|
GO:0050966 |
4 |
0.150
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.149
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.148
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.147
|
|
|
|
osteoclast development
|
GO:0036035 |
9 |
0.147
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.146
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.146
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.145
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.141
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.140
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.139
|
Mouse |
|
|
antigen processing and presentation of exogenous peptide antigen
|
GO:0002478 |
21 |
0.139
|
Mouse |
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.136
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.136
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.136
|
|
|
|
uterus development
|
GO:0060065 |
16 |
0.135
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.135
|
Mouse |
|
|
positive regulation of type ii hypersensitivity
|
GO:0002894 |
4 |
0.134
|
Mouse |
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.133
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.133
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
20 |
0.132
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.132
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.130
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.128
|
|
|
|
regulation of corticosterone secretion
|
GO:2000852 |
2 |
0.128
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.128
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.126
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.123
|
Mouse |
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.121
|
|
|
|
regulation of regulatory t cell differentiation
|
GO:0045589 |
7 |
0.121
|
|
|
|
serotonin secretion involved in inflammatory response
|
GO:0002442 |
4 |
0.121
|
Mouse |
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.120
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.120
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.120
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.119
|
|
|
|
nk t cell proliferation
|
GO:0001866 |
2 |
0.119
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.119
|
Mouse |
|
|
glucose transport
|
GO:0015758 |
56 |
0.119
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.118
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.117
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.117
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.116
|
Mouse |
|
|
positive regulation of mast cell degranulation
|
GO:0043306 |
10 |
0.115
|
Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.114
|
|
|
|
cellular response to molecule of fungal origin
|
GO:0071226 |
2 |
0.113
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
31 |
0.113
|
|
|
|
interleukin 8 secretion
|
GO:0072606 |
3 |
0.113
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.112
|
|
|
|
platelet aggregation
|
GO:0070527 |
20 |
0.111
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.110
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.110
|
|
|
|
positive regulation of peptide hormone secretion
|
GO:0090277 |
31 |
0.110
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.110
|
Mouse |
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
24 |
0.110
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.109
|
Mouse |
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
11 |
0.109
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.109
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.108
|
|
|
|
positive regulation of peptide secretion
|
GO:0002793 |
33 |
0.108
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.108
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.107
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.107
|
Mouse |
|
|
negative regulation of interleukin 8 secretion
|
GO:2000483 |
1 |
0.104
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.104
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.104
|
Mouse |
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.104
|
Mouse |
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.103
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.103
|
|
|
|
regulation of natural killer cell activation
|
GO:0032814 |
22 |
0.103
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.102
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
29 |
0.102
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.101
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.101
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.101
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.101
|
Mouse |
|
|
platelet activation
|
GO:0030168 |
40 |
0.099
|
Mouse |
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.099
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.098
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.098
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.097
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.097
|
|
|
|
negative regulation of toll like receptor 4 signaling pathway
|
GO:0034144 |
3 |
0.096
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.095
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.094
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.093
|
|
|
|
memory
|
GO:0007613 |
58 |
0.092
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.092
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.092
|
Mouse |
|
|
regulation of organelle assembly
|
GO:1902115 |
19 |
0.090
|
|
|
|
detection of mechanical stimulus
|
GO:0050982 |
27 |
0.089
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.089
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.088
|
Mouse |
|
|
regulation of type iii hypersensitivity
|
GO:0001803 |
3 |
0.087
|
Mouse |
|
|
parallel actin filament bundle assembly
|
GO:0030046 |
2 |
0.087
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.086
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.086
|
Mouse |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.086
|
|
|
|
exocrine system development
|
GO:0035272 |
45 |
0.084
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.084
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.083
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.083
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.083
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.083
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.083
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.082
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.081
|
|
|
|
neutrophil degranulation
|
GO:0043312 |
6 |
0.080
|
|
|
|
regulation of gamma delta t cell differentiation
|
GO:0045586 |
9 |
0.080
|
|
|
|
negative regulation of lymphocyte mediated immunity
|
GO:0002707 |
21 |
0.080
|
|
|
|
negative regulation of mast cell proliferation
|
GO:0070667 |
1 |
0.079
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.079
|
Mouse |
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.078
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.077
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
26 |
0.076
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.076
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
28 |
0.076
|
Mouse |
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
29 |
0.076
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.075
|
Mouse |
|
|
defense response to virus
|
GO:0051607 |
68 |
0.075
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.075
|
|
|
|
macrophage activation
|
GO:0042116 |
27 |
0.075
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.074
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.074
|
Mouse |
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.074
|
|
|
|
toll like receptor 4 signaling pathway
|
GO:0034142 |
9 |
0.073
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.073
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.072
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.072
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.071
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.071
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.071
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.071
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.070
|
|
|
|
response to platelet derived growth factor
|
GO:0036119 |
6 |
0.070
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.070
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.070
|
|
|
|
negative regulation of camp mediated signaling
|
GO:0043951 |
3 |
0.069
|
|
|
|
lysosome localization
|
GO:0032418 |
20 |
0.069
|
Mouse |
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.069
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.069
|
|
|
|
pituitary gland development
|
GO:0021983 |
38 |
0.069
|
|
|
|
hypersensitivity
|
GO:0002524 |
10 |
0.068
|
Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.068
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.068
|
|
|
|
serotonin secretion by platelet
|
GO:0002554 |
3 |
0.068
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.068
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.068
|
Mouse |
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
44 |
0.067
|
|
|
|
positive regulation of regulated secretory pathway
|
GO:1903307 |
10 |
0.067
|
Mouse |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.067
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.066
|
|
|
|
interleukin 2 mediated signaling pathway
|
GO:0038110 |
2 |
0.066
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.066
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.065
|
Mouse |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.065
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
26 |
0.065
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.064
|
|
|
|
regulation of phosphatidylinositol 3 kinase activity
|
GO:0043551 |
14 |
0.064
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.064
|
Mouse |
|
|
isotype switching to igg isotypes
|
GO:0048291 |
10 |
0.064
|
|
|
|
negative regulation of muscle contraction
|
GO:0045932 |
12 |
0.064
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.063
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.063
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.063
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.063
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.062
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.062
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.062
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.062
|
|
|
|
natural killer cell differentiation
|
GO:0001779 |
21 |
0.062
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.062
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.062
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.061
|
Mouse |
|
|
lymphocyte anergy
|
GO:0002249 |
4 |
0.061
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.061
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
31 |
0.061
|
|
|
|
corticosterone secretion
|
GO:0035934 |
3 |
0.061
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.061
|
|
|
|
receptor internalization
|
GO:0031623 |
16 |
0.061
|
|
|
|
cell cell junction assembly
|
GO:0007043 |
27 |
0.061
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.060
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.060
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.059
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.059
|
|
|
|
filtration diaphragm assembly
|
GO:0036058 |
1 |
0.059
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.059
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
6 |
0.059
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.058
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.057
|
Mouse |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.057
|
|
|
|
positive regulation of smooth muscle contraction
|
GO:0045987 |
7 |
0.057
|
|
|
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
6 |
0.057
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
11 |
0.056
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.056
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.056
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.056
|
Mouse |
|
|
transition metal ion homeostasis
|
GO:0055076 |
54 |
0.056
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.056
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.056
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.055
|
|
|
|
positive regulation of growth hormone secretion
|
GO:0060124 |
3 |
0.055
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.055
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.054
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.054
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.054
|
Mouse |
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.053
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.053
|
Mouse |
|
|
phagocytosis
|
GO:0006909 |
66 |
0.053
|
Mouse |
|
|
positive regulation of dendritic cell apoptotic process
|
GO:2000670 |
3 |
0.052
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.052
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.052
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.052
|
|
|
|
somatotropin secreting cell development
|
GO:0060133 |
2 |
0.052
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.051
|
Mouse |
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.051
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.051
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.050
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.050
|
|
|
|
positive regulation of translational initiation
|
GO:0045948 |
4 |
0.050
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.050
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.050
|
|
|
|
regulation of tube size
|
GO:0035150 |
57 |
0.050
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
19 |
0.050
|
|
|
|
positive regulation of t cell mediated immunity
|
GO:0002711 |
24 |
0.049
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.049
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.048
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.048
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.048
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.048
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.048
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.048
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.048
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.048
|
Mouse |
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.048
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.048
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.048
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.047
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.047
|
|
|
|
general adaptation syndrome behavioral process
|
GO:0051867 |
1 |
0.047
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.047
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
25 |
0.047
|
|
|
|
sensory perception of pain
|
GO:0019233 |
47 |
0.047
|
|
|
|
regulation of coagulation
|
GO:0050818 |
31 |
0.047
|
Mouse |
|
|
diencephalon development
|
GO:0021536 |
63 |
0.047
|
|
|
|
granulocyte differentiation
|
GO:0030851 |
17 |
0.047
|
|
|
|
gamma delta t cell lineage commitment
|
GO:0002365 |
1 |
0.046
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.046
|
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
14 |
0.046
|
Mouse |
|
|
hemostasis
|
GO:0007599 |
78 |
0.046
|
Mouse |
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.046
|
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.046
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.046
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.045
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.045
|
|
