Mus musculus

0 known processes

Ankib1

ankyrin repeat and IBR domain containing 1

(Aliases: MGC90780,mKIAA1386,2310061P20Rik,C80642,4631416I11Rik,AW494740)

Ankib1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small gtpase mediated signal transduction GO:0007264 97 0.102
regulation of cellular amino acid metabolic process GO:0006521 5 0.083
regulation of cell activation GO:0050865 289 0.075
purine nucleotide metabolic process GO:0006163 302 0.071
protein ubiquitination GO:0016567 171 0.071
carbohydrate derivative catabolic process GO:1901136 231 0.069
organonitrogen compound catabolic process GO:1901565 264 0.068
heterocycle catabolic process GO:0046700 280 0.065
purine ribonucleotide metabolic process GO:0009150 290 0.064
aromatic compound catabolic process GO:0019439 286 0.063
cellular nitrogen compound catabolic process GO:0044270 280 0.063
organic cyclic compound catabolic process GO:1901361 295 0.062
guanosine containing compound metabolic process GO:1901068 144 0.061
regulation of organelle organization GO:0033043 289 0.060
nucleobase containing small molecule metabolic process GO:0055086 352 0.060
ras protein signal transduction GO:0007265 77 0.057
chemotaxis GO:0006935 247 0.056
glycosyl compound metabolic process GO:1901657 246 0.055
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.055
glycoprotein metabolic process GO:0009100 116 0.055
cellular amino acid metabolic process GO:0006520 103 0.054
cell adhesion GO:0007155 329 0.054
cellular amine metabolic process GO:0044106 44 0.054
ribonucleoside metabolic process GO:0009119 245 0.053
ribonucleotide metabolic process GO:0009259 291 0.052
nucleoside catabolic process GO:0009164 206 0.052
purine ribonucleoside metabolic process GO:0046128 241 0.051
purine nucleotide catabolic process GO:0006195 211 0.049
ribose phosphate metabolic process GO:0019693 291 0.049
nucleoside metabolic process GO:0009116 246 0.048
amine metabolic process GO:0009308 45 0.048
cation transport GO:0006812 399 0.047
glycosyl compound catabolic process GO:1901658 206 0.047
rac protein signal transduction GO:0016601 13 0.045
actin cytoskeleton organization GO:0030036 220 0.045
cellular lipid metabolic process GO:0044255 323 0.044
protein modification by small protein conjugation or removal GO:0070647 207 0.044
leukocyte differentiation GO:0002521 342 0.043
organophosphate catabolic process GO:0046434 232 0.043
cellular homeostasis GO:0019725 240 0.043
posttranscriptional regulation of gene expression GO:0010608 155 0.043
ion transmembrane transport GO:0034220 361 0.042
protein modification by small protein conjugation GO:0032446 187 0.042
regulation of cellular ketone metabolic process GO:0010565 66 0.041
macromolecule catabolic process GO:0009057 281 0.041
nucleoside triphosphate metabolic process GO:0009141 230 0.041
organelle localization GO:0051640 179 0.041
endocytosis GO:0006897 168 0.040
purine nucleoside catabolic process GO:0006152 205 0.039
rho protein signal transduction GO:0007266 32 0.039
nucleoside phosphate metabolic process GO:0006753 338 0.038
purine containing compound metabolic process GO:0072521 311 0.038
regulation of cellular component biogenesis GO:0044087 181 0.038
muscle cell differentiation GO:0042692 261 0.038
cellular ketone metabolic process GO:0042180 84 0.037
synaptic transmission GO:0007268 329 0.037
peptidyl amino acid modification GO:0018193 336 0.037
ribonucleoside triphosphate metabolic process GO:0009199 220 0.037
positive regulation of cellular catabolic process GO:0031331 148 0.036
purine nucleoside triphosphate metabolic process GO:0009144 226 0.035
regulation of ras gtpase activity GO:0032318 88 0.035
regulation of neuron differentiation GO:0045664 281 0.035
regulation of lymphocyte activation GO:0051249 240 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
nucleotide metabolic process GO:0009117 332 0.035
leukocyte proliferation GO:0070661 172 0.035
metal ion homeostasis GO:0055065 189 0.035
ribonucleoside catabolic process GO:0042454 206 0.034
guanosine containing compound catabolic process GO:1901069 144 0.034
male gamete generation GO:0048232 285 0.033
regulation of nucleotide catabolic process GO:0030811 122 0.033
nucleoside phosphate catabolic process GO:1901292 222 0.033
t cell proliferation GO:0042098 120 0.033
regulation of leukocyte differentiation GO:1902105 159 0.033
ribonucleotide catabolic process GO:0009261 208 0.033
protein polyubiquitination GO:0000209 33 0.032
regulation of cellular amine metabolic process GO:0033238 20 0.032
nucleoside triphosphate catabolic process GO:0009143 205 0.032
nitrogen compound transport GO:0071705 271 0.032
purine ribonucleotide catabolic process GO:0009154 208 0.031
regulation of actin cytoskeleton organization GO:0032956 84 0.031
myeloid cell differentiation GO:0030099 233 0.030
purine nucleoside metabolic process GO:0042278 241 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.030
regulation of endocytosis GO:0030100 69 0.029
regulation of nucleotide metabolic process GO:0006140 169 0.029
spermatogenesis GO:0007283 284 0.029
dna metabolic process GO:0006259 303 0.029
anion transport GO:0006820 177 0.029
regulation of cytoskeleton organization GO:0051493 122 0.029
positive regulation of protein modification process GO:0031401 299 0.029
regulation of hydrolase activity GO:0051336 246 0.029
gtp metabolic process GO:0046039 144 0.029
negative regulation of phosphate metabolic process GO:0045936 184 0.028
regulation of t cell activation GO:0050863 170 0.028
carbohydrate derivative biosynthetic process GO:1901137 183 0.028
cellular ion homeostasis GO:0006873 165 0.028
oocyte construction GO:0007308 2 0.027
macromolecule glycosylation GO:0043413 55 0.027
actin filament organization GO:0007015 113 0.027
regulation of purine nucleotide metabolic process GO:1900542 169 0.027
regulation of protein localization GO:0032880 231 0.027
transmembrane transport GO:0055085 412 0.026
purine containing compound catabolic process GO:0072523 213 0.026
positive regulation of hydrolase activity GO:0051345 148 0.026
microtubule based process GO:0007017 236 0.026
organelle assembly GO:0070925 177 0.026
lymphocyte proliferation GO:0046651 164 0.026
developmental maturation GO:0021700 193 0.026
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.026
t cell activation GO:0042110 289 0.026
regulation of cellular catabolic process GO:0031329 242 0.026
purine ribonucleoside catabolic process GO:0046130 205 0.026
nucleotide catabolic process GO:0009166 217 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
fertilization GO:0009566 127 0.025
protein glycosylation GO:0006486 55 0.025
ribonucleoside triphosphate catabolic process GO:0009203 199 0.025
homeostasis of number of cells GO:0048872 210 0.025
regulation of vesicle mediated transport GO:0060627 139 0.025
regulation of membrane potential GO:0042391 192 0.025
protein catabolic process GO:0030163 221 0.025
dephosphorylation GO:0016311 129 0.025
organic hydroxy compound metabolic process GO:1901615 203 0.025
positive regulation of protein phosphorylation GO:0001934 242 0.024
positive regulation of gtpase activity GO:0043547 85 0.024
cellular response to lipid GO:0071396 145 0.024
organonitrogen compound biosynthetic process GO:1901566 192 0.024
response to lipopolysaccharide GO:0032496 128 0.024
purine nucleoside triphosphate catabolic process GO:0009146 203 0.024
regulation of nucleoside metabolic process GO:0009118 130 0.024
b cell activation GO:0042113 161 0.024
glycoprotein biosynthetic process GO:0009101 89 0.024
modification dependent macromolecule catabolic process GO:0043632 133 0.024
locomotory behavior GO:0007626 195 0.024
regulation of ion transport GO:0043269 215 0.024
ubiquitin dependent protein catabolic process GO:0006511 129 0.023
mitochondrion organization GO:0007005 134 0.023
cellular response to dna damage stimulus GO:0006974 207 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.023
hematopoietic progenitor cell differentiation GO:0002244 143 0.022
membrane organization GO:0061024 245 0.022
axon guidance GO:0007411 141 0.022
response to topologically incorrect protein GO:0035966 25 0.022
regulation of cell projection organization GO:0031344 206 0.022
response to organonitrogen compound GO:0010243 246 0.022
phospholipid metabolic process GO:0006644 87 0.022
regulation of b cell activation GO:0050864 81 0.022
microtubule cytoskeleton organization GO:0000226 157 0.022
compound eye development GO:0048749 1 0.021
cell substrate adhesion GO:0031589 130 0.021
positive regulation of lymphocyte activation GO:0051251 140 0.021
negative regulation of synapse assembly GO:0051964 3 0.021
divalent inorganic cation homeostasis GO:0072507 138 0.021
mitotic cell cycle GO:0000278 195 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.021
intracellular protein transport GO:0006886 204 0.021
digestive tract development GO:0048565 190 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
regulation of gtp catabolic process GO:0033124 113 0.021
cytoplasmic transport GO:0016482 234 0.020
regulation of transferase activity GO:0051338 263 0.020
multicellular organismal signaling GO:0035637 91 0.020
sequestering of metal ion GO:0051238 19 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.020
regulation of purine nucleotide catabolic process GO:0033121 122 0.020
germ cell development GO:0007281 185 0.020
mitochondrion distribution GO:0048311 4 0.019
gtp catabolic process GO:0006184 143 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
carbohydrate metabolic process GO:0005975 230 0.019
maintenance of location GO:0051235 89 0.019
cell activation involved in immune response GO:0002263 126 0.019
regulation of clathrin mediated endocytosis GO:2000369 4 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
inorganic cation transmembrane transport GO:0098662 207 0.019
regulation of cytokine production GO:0001817 266 0.019
protein autophosphorylation GO:0046777 61 0.019
oocyte axis specification GO:0007309 2 0.019
response to growth factor GO:0070848 198 0.019
regulation of system process GO:0044057 200 0.019
regulation of actin filament based process GO:0032970 99 0.019
regulation of cell migration GO:0030334 219 0.019
chromatin modification GO:0016568 187 0.019
regulation of rho protein signal transduction GO:0035023 71 0.019
inorganic ion transmembrane transport GO:0098660 234 0.018
regulation of lymphocyte differentiation GO:0045619 107 0.018
respiratory tube development GO:0030323 167 0.018
cellular chemical homeostasis GO:0055082 215 0.018
lymphocyte differentiation GO:0030098 242 0.018
regulation of neuron death GO:1901214 134 0.018
cytokine production GO:0001816 319 0.018
calcium ion homeostasis GO:0055074 127 0.018
positive regulation of cell activation GO:0050867 158 0.018
positive regulation of gtp catabolic process GO:0033126 85 0.018
regulation of kinase activity GO:0043549 249 0.018
positive regulation of transferase activity GO:0051347 167 0.018
regulation of cell adhesion GO:0030155 154 0.018
positive regulation of protein kinase activity GO:0045860 144 0.017
learning or memory GO:0007611 148 0.017
anatomical structure homeostasis GO:0060249 145 0.017
lung development GO:0030324 164 0.017
nuclear division GO:0000280 158 0.017
positive regulation of nervous system development GO:0051962 221 0.017
regulation of neuron projection development GO:0010975 169 0.017
regulation of leukocyte proliferation GO:0070663 121 0.017
activation of immune response GO:0002253 138 0.017
regulation of cell motility GO:2000145 236 0.017
cell type specific apoptotic process GO:0097285 268 0.017
blood vessel morphogenesis GO:0048514 285 0.017
epithelial tube morphogenesis GO:0060562 303 0.017
cation transmembrane transport GO:0098655 266 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.017
neuron projection guidance GO:0097485 141 0.017
digestive system development GO:0055123 200 0.017
glycosylation GO:0070085 62 0.017
cellular metal ion homeostasis GO:0006875 151 0.017
regulation of protein complex assembly GO:0043254 83 0.017
negative regulation of immune system process GO:0002683 209 0.017
positive regulation of ras gtpase activity GO:0032320 65 0.017
regulation of protein kinase activity GO:0045859 232 0.017
immune response regulating signaling pathway GO:0002764 125 0.017
regionalization GO:0003002 337 0.017
single organism cell adhesion GO:0098602 156 0.017
regulation of neuron apoptotic process GO:0043523 122 0.017
establishment or maintenance of cell polarity GO:0007163 86 0.017
cellular macromolecule catabolic process GO:0044265 206 0.016
regulation of myeloid cell differentiation GO:0045637 96 0.016
regulation of secretion GO:0051046 274 0.016
glycerophospholipid metabolic process GO:0006650 71 0.016
sequestering of calcium ion GO:0051208 18 0.016
cellular calcium ion homeostasis GO:0006874 119 0.016
cofactor metabolic process GO:0051186 80 0.016
regulation of mapk cascade GO:0043408 248 0.016
regulation of ras protein signal transduction GO:0046578 114 0.016
cell growth GO:0016049 130 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
wound healing GO:0042060 157 0.016
regulation of secretion by cell GO:1903530 249 0.016
lymphocyte homeostasis GO:0002260 64 0.016
inflammatory response GO:0006954 244 0.016
actin polymerization or depolymerization GO:0008154 54 0.016
cognition GO:0050890 149 0.016
regulation of t cell proliferation GO:0042129 92 0.016
immune response activating signal transduction GO:0002757 116 0.016
multicellular organismal homeostasis GO:0048871 164 0.015
olfactory learning GO:0008355 2 0.015
embryonic epithelial tube formation GO:0001838 130 0.015
regulation of translation GO:0006417 71 0.015
multi multicellular organism process GO:0044706 109 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.015
chromatin organization GO:0006325 206 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
epithelial cell development GO:0002064 159 0.015
regulation of t cell differentiation GO:0045580 83 0.015
positive regulation of neuron differentiation GO:0045666 141 0.015
peptide transport GO:0015833 133 0.015
lipid biosynthetic process GO:0008610 179 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.015
divalent metal ion transport GO:0070838 172 0.015
leukocyte migration GO:0050900 124 0.015
transmission of nerve impulse GO:0019226 76 0.015
leukocyte mediated immunity GO:0002443 174 0.015
respiratory system development GO:0060541 190 0.015
mapk cascade GO:0000165 281 0.015
myeloid cell homeostasis GO:0002262 114 0.015
regulation of lymphocyte proliferation GO:0050670 117 0.015
antigen receptor mediated signaling pathway GO:0050851 64 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
positive regulation of cell development GO:0010720 237 0.015
intracellular mrna localization GO:0008298 4 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
wnt signaling pathway GO:0016055 188 0.014
multicellular organism growth GO:0035264 161 0.014
ossification GO:0001503 216 0.014
protein polymerization GO:0051258 57 0.014
negative regulation of molecular function GO:0044092 258 0.014
positive regulation of leukocyte differentiation GO:1902107 86 0.014
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
spermatid development GO:0007286 108 0.014
dendrite development GO:0016358 115 0.014
cellular protein complex assembly GO:0043623 116 0.014
hindbrain development GO:0030902 128 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
action potential GO:0001508 78 0.014
lateral inhibition GO:0046331 1 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
translation GO:0006412 93 0.014
regulation of hormone levels GO:0010817 211 0.014
cellular response to lipopolysaccharide GO:0071222 77 0.014
endodermal cell fate specification GO:0001714 4 0.014
axonogenesis GO:0007409 274 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
response to oxidative stress GO:0006979 123 0.014
dna recombination GO:0006310 92 0.014
divalent inorganic cation transport GO:0072511 178 0.014
cell matrix adhesion GO:0007160 68 0.014
sensory organ morphogenesis GO:0090596 242 0.014
metencephalon development GO:0022037 89 0.014
cation homeostasis GO:0055080 212 0.013
protein localization to organelle GO:0033365 185 0.013
positive regulation of cell adhesion GO:0045785 80 0.013
positive regulation of protein transport GO:0051222 93 0.013
sensory perception GO:0007600 245 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
t cell differentiation GO:0030217 174 0.013
neural tube development GO:0021915 160 0.013
cellular protein catabolic process GO:0044257 155 0.013
histone modification GO:0016570 159 0.013
actin filament polymerization GO:0030041 44 0.013
apoptotic signaling pathway GO:0097190 306 0.013
tissue homeostasis GO:0001894 115 0.013
establishment of organelle localization GO:0051656 122 0.013
response to acid chemical GO:0001101 111 0.013
positive regulation of nucleotide catabolic process GO:0030813 88 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
glycerolipid metabolic process GO:0046486 122 0.013
gonad development GO:0008406 141 0.013
regulation of cellular component size GO:0032535 121 0.013
regulation of cell growth GO:0001558 91 0.013
gene silencing GO:0016458 38 0.013
protein palmitoylation GO:0018345 14 0.013
cell recognition GO:0008037 83 0.013
establishment of mitochondrion localization GO:0051654 4 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
lipid localization GO:0010876 126 0.012
heart morphogenesis GO:0003007 178 0.012
epidermis development GO:0008544 187 0.012
leukocyte activation involved in immune response GO:0002366 126 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
i kappab kinase nf kappab signaling GO:0007249 85 0.012
tissue remodeling GO:0048771 102 0.012
regulation of rac protein signal transduction GO:0035020 19 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
positive regulation of cell projection organization GO:0031346 95 0.012
extracellular matrix organization GO:0030198 147 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.012
neuronal action potential GO:0019228 54 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
skeletal muscle organ development GO:0060538 163 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
endomembrane system organization GO:0010256 147 0.012
rhythmic process GO:0048511 174 0.012
exocytosis GO:0006887 121 0.012
positive regulation of t cell activation GO:0050870 101 0.012
positive regulation of nucleoside metabolic process GO:0045979 91 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
regulation of actin filament length GO:0030832 45 0.012
calcium ion transport GO:0006816 159 0.012
neuron apoptotic process GO:0051402 142 0.011
oxidation reduction process GO:0055114 342 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
ear development GO:0043583 200 0.011
regulation of inflammatory response GO:0050727 147 0.011
muscle tissue development GO:0060537 308 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
regulation of transmembrane transport GO:0034762 128 0.011
spermatid differentiation GO:0048515 115 0.011
gland development GO:0048732 330 0.011
transition metal ion homeostasis GO:0055076 54 0.011
organelle fission GO:0048285 170 0.011
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.011
myotube differentiation GO:0014902 105 0.011
negative regulation of growth GO:0045926 99 0.011
b cell homeostasis GO:0001782 34 0.011
bone development GO:0060348 120 0.011
digestive tract morphogenesis GO:0048546 147 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
positive regulation of kinase activity GO:0033674 155 0.011
central nervous system neuron differentiation GO:0021953 162 0.011
positive regulation of immune effector process GO:0002699 107 0.011
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
covalent chromatin modification GO:0016569 163 0.011
negative regulation of nervous system development GO:0051961 156 0.011
midgut development GO:0007494 4 0.011
immune effector process GO:0002252 321 0.011
lymphocyte activation involved in immune response GO:0002285 93 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
response to endoplasmic reticulum stress GO:0034976 53 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
cell fate commitment GO:0045165 210 0.011
cytokinetic process GO:0032506 2 0.011
epithelial cell proliferation GO:0050673 174 0.011
nuclear transport GO:0051169 139 0.010
protein processing GO:0016485 163 0.010
negative regulation of neuron apoptotic process GO:0043524 92 0.010
cellularization GO:0007349 1 0.010
phagocytosis GO:0006909 66 0.010
regulation of homeostatic process GO:0032844 182 0.010
negative regulation of protein modification process GO:0031400 163 0.010
cellular response to acid chemical GO:0071229 68 0.010
defecation GO:0030421 1 0.010
positive regulation of wnt signaling pathway GO:0030177 45 0.010
cellular response to molecule of bacterial origin GO:0071219 83 0.010
neural tube formation GO:0001841 108 0.010
protein secretion GO:0009306 111 0.010
blood circulation GO:0008015 195 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.010
lymphocyte mediated immunity GO:0002449 139 0.010
leukocyte chemotaxis GO:0030595 69 0.010
innate immune response GO:0045087 157 0.010
organic anion transport GO:0015711 137 0.010
development of primary sexual characteristics GO:0045137 143 0.010
positive regulation of rac gtpase activity GO:0032855 14 0.010
regulation of ossification GO:0030278 112 0.010
positive regulation of cell death GO:0010942 224 0.010
amide transport GO:0042886 138 0.010

Ankib1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.015
organ system cancer DOID:0050686 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.015
central nervous system disease DOID:331 0 0.015
eye and adnexa disease DOID:1492 0 0.013
sensory system disease DOID:0050155 0 0.013
disease of mental health DOID:150 0 0.012
neurodegenerative disease DOID:1289 0 0.011