Mus musculus

85 known processes

Sh2b2

SH2B adaptor protein 2

(Aliases: Aps)

Sh2b2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular ketone metabolic process GO:0010565 66 0.303
amine metabolic process GO:0009308 45 0.249
cellular amine metabolic process GO:0044106 44 0.202
regulation of cellular amine metabolic process GO:0033238 20 0.199
carbohydrate metabolic process GO:0005975 230 0.192
forebrain development GO:0030900 302 0.191
cellular amino acid metabolic process GO:0006520 103 0.189
regionalization GO:0003002 337 0.188
cellular ketone metabolic process GO:0042180 84 0.183
regulation of cellular amino acid metabolic process GO:0006521 5 0.174
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.153
negative regulation of protein modification process GO:0031400 163 0.151
developmental maturation GO:0021700 193 0.128
bone development GO:0060348 120 0.128
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.124
skeletal system development GO:0001501 356 0.122
appendage morphogenesis GO:0035107 149 0.119
negative regulation of cellular protein metabolic process GO:0032269 247 0.118
ossification GO:0001503 216 0.117
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.113
morphogenesis of embryonic epithelium GO:0016331 159 0.110
regulation of neuron differentiation GO:0045664 281 0.107
urogenital system development GO:0001655 261 0.104
small molecule biosynthetic process GO:0044283 132 0.102
connective tissue development GO:0061448 179 0.099
protein ubiquitination GO:0016567 171 0.098
negative regulation of protein phosphorylation GO:0001933 126 0.095
limb development GO:0060173 166 0.094
negative regulation of protein metabolic process GO:0051248 282 0.091
mesonephric tubule development GO:0072164 94 0.089
negative regulation of cellular amine metabolic process GO:0033239 1 0.086
positive regulation of cellular amine metabolic process GO:0033240 5 0.085
lipid biosynthetic process GO:0008610 179 0.082
negative regulation of phosphate metabolic process GO:0045936 184 0.082
negative regulation of phosphorylation GO:0042326 166 0.082
ras protein signal transduction GO:0007265 77 0.079
Rat
regulation of transferase activity GO:0051338 263 0.078
negative regulation of transferase activity GO:0051348 85 0.077
negative regulation of molecular function GO:0044092 258 0.077
respiratory system development GO:0060541 190 0.076
protein catabolic process GO:0030163 221 0.076
neural tube development GO:0021915 160 0.075
regulation of membrane potential GO:0042391 192 0.075
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.073
positive regulation of nervous system development GO:0051962 221 0.073
cellular lipid metabolic process GO:0044255 323 0.072
kidney development GO:0001822 213 0.071
negative regulation of hormone metabolic process GO:0032351 4 0.071
negative regulation of kinase activity GO:0033673 81 0.070
mapk cascade GO:0000165 281 0.070
peptidyl tyrosine modification GO:0018212 145 0.070
regulation of protein kinase activity GO:0045859 232 0.069
organic hydroxy compound metabolic process GO:1901615 203 0.069
cellular response to peptide GO:1901653 92 0.069
spermatogenesis GO:0007283 284 0.068
regulation of secretion by cell GO:1903530 249 0.068
cartilage development GO:0051216 140 0.067
macromolecule catabolic process GO:0009057 281 0.067
organ growth GO:0035265 117 0.067
negative regulation of cell proliferation GO:0008285 296 0.067
peptidyl amino acid modification GO:0018193 336 0.066
central nervous system neuron differentiation GO:0021953 162 0.065
skeletal system morphogenesis GO:0048705 203 0.064
negative regulation of cell activation GO:0050866 111 0.063
axon guidance GO:0007411 141 0.063
sensory organ morphogenesis GO:0090596 242 0.063
appendage development GO:0048736 166 0.063
male gamete generation GO:0048232 285 0.063
leukocyte differentiation GO:0002521 342 0.061
regulation of lymphocyte activation GO:0051249 240 0.061
negative regulation of hormone biosynthetic process GO:0032353 4 0.061
respiratory tube development GO:0030323 167 0.060
regulation of cell activation GO:0050865 289 0.060
regulation of ossification GO:0030278 112 0.059
alcohol metabolic process GO:0006066 116 0.058
positive regulation of neuron differentiation GO:0045666 141 0.058
oxidation reduction process GO:0055114 342 0.058
positive regulation of ossification GO:0045778 47 0.056
positive regulation of cell death GO:0010942 224 0.055
protein modification by small protein conjugation or removal GO:0070647 207 0.055
mesonephric epithelium development GO:0072163 94 0.054
regulation of carbohydrate metabolic process GO:0006109 75 0.054
transmembrane transport GO:0055085 412 0.054
glycerolipid metabolic process GO:0046486 122 0.052
regulation of mapk cascade GO:0043408 248 0.052
renal system development GO:0072001 225 0.052
regulation of defense response GO:0031347 233 0.051
regulation of kinase activity GO:0043549 249 0.051
cerebral cortex radially oriented cell migration GO:0021799 31 0.051
regulation of anatomical structure size GO:0090066 178 0.051
peptidyl tyrosine phosphorylation GO:0018108 143 0.051
guanosine containing compound catabolic process GO:1901069 144 0.050
lateral inhibition GO:0046331 1 0.050
bone morphogenesis GO:0060349 78 0.050
regulation of lipid metabolic process GO:0019216 118 0.049
regulation of establishment of protein localization GO:0070201 181 0.049
negative regulation of lymphocyte activation GO:0051250 91 0.049
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 17 0.049
chondrocyte differentiation GO:0002062 72 0.048
negative regulation of alpha beta t cell activation GO:0046636 18 0.048
response to peptide hormone GO:0043434 127 0.047
positive regulation of cell development GO:0010720 237 0.046
cation transmembrane transport GO:0098655 266 0.046
endochondral bone morphogenesis GO:0060350 50 0.046
axonogenesis GO:0007409 274 0.046
regulation of cellular catabolic process GO:0031329 242 0.045
negative regulation of phosphorus metabolic process GO:0010563 184 0.045
kidney epithelium development GO:0072073 121 0.045
ureteric bud development GO:0001657 94 0.045
t cell activation GO:0042110 289 0.044
regulation of neuron projection development GO:0010975 169 0.044
germ cell development GO:0007281 185 0.044
developmental growth involved in morphogenesis GO:0060560 138 0.044
stem cell proliferation GO:0072089 117 0.044
negative regulation of immune system process GO:0002683 209 0.043
negative regulation of map kinase activity GO:0043407 34 0.043
muscle cell differentiation GO:0042692 261 0.043
primary neural tube formation GO:0014020 95 0.042
regulation of reproductive process GO:2000241 66 0.042
regulation of organ morphogenesis GO:2000027 144 0.041
regulation of lymphocyte proliferation GO:0050670 117 0.041
glial cell differentiation GO:0010001 131 0.041
limb morphogenesis GO:0035108 149 0.041
regulation of organelle organization GO:0033043 289 0.041
Mouse
nerve development GO:0021675 67 0.041
organic hydroxy compound biosynthetic process GO:1901617 77 0.041
organic acid biosynthetic process GO:0016053 86 0.041
regulation of protein localization GO:0032880 231 0.040
negative regulation of t cell activation GO:0050868 65 0.040
lymphocyte differentiation GO:0030098 242 0.040
hexose metabolic process GO:0019318 98 0.040
cellular response to organonitrogen compound GO:0071417 145 0.040
positive regulation of programmed cell death GO:0043068 218 0.039
negative regulation of intracellular signal transduction GO:1902532 167 0.039
lymphocyte anergy GO:0002249 4 0.039
brown fat cell differentiation GO:0050873 36 0.039
camera type eye development GO:0043010 266 0.039
morphogenesis of a branching structure GO:0001763 203 0.038
cellular response to insulin stimulus GO:0032869 78 0.038
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.038
regulation of inflammatory response GO:0050727 147 0.038
neuron death GO:0070997 154 0.037
inflammatory response GO:0006954 244 0.037
response to peptide GO:1901652 136 0.037
regulation of system process GO:0044057 200 0.037
regulation of leukocyte differentiation GO:1902105 159 0.037
aromatic compound catabolic process GO:0019439 286 0.036
regulation of heart contraction GO:0008016 77 0.036
cellular macromolecule catabolic process GO:0044265 206 0.036
phospholipid metabolic process GO:0006644 87 0.036
cell adhesion GO:0007155 329 0.036
eye photoreceptor cell differentiation GO:0001754 41 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.036
embryonic limb morphogenesis GO:0030326 126 0.036
organonitrogen compound catabolic process GO:1901565 264 0.036
neuronal action potential GO:0019228 54 0.035
action potential GO:0001508 78 0.035
nucleotide metabolic process GO:0009117 332 0.035
regulation of cell projection organization GO:0031344 206 0.035
pallium development GO:0021543 120 0.035
carboxylic acid biosynthetic process GO:0046394 86 0.035
regulation of neuron death GO:1901214 134 0.035
organophosphate catabolic process GO:0046434 232 0.035
telencephalon development GO:0021537 186 0.035
fat cell differentiation GO:0045444 160 0.034
regulation of alpha beta t cell activation GO:0046634 53 0.034
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.034
telencephalon cell migration GO:0022029 55 0.033
regulation of ras protein signal transduction GO:0046578 114 0.033
Rat
regulation of osteoblast differentiation GO:0045667 67 0.032
positive regulation of apoptotic process GO:0043065 217 0.032
regulation of protein serine threonine kinase activity GO:0071900 157 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.032
epithelial tube morphogenesis GO:0060562 303 0.032
cellular protein catabolic process GO:0044257 155 0.032
epithelial tube formation GO:0072175 130 0.031
heart morphogenesis GO:0003007 178 0.031
myeloid cell differentiation GO:0030099 233 0.031
negative regulation of cell development GO:0010721 169 0.031
regulation of hormone levels GO:0010817 211 0.031
steroid metabolic process GO:0008202 119 0.031
negative regulation of nervous system development GO:0051961 156 0.031
myeloid leukocyte differentiation GO:0002573 119 0.031
positive regulation of cellular catabolic process GO:0031331 148 0.031
positive regulation of cell activation GO:0050867 158 0.030
odontogenesis of dentin containing tooth GO:0042475 66 0.030
cellular response to hormone stimulus GO:0032870 150 0.030
response to lipopolysaccharide GO:0032496 128 0.030
cerebral cortex development GO:0021987 86 0.030
positive regulation of gtpase activity GO:0043547 85 0.030
odontogenesis GO:0042476 78 0.030
neural tube formation GO:0001841 108 0.030
regulation of lymphocyte differentiation GO:0045619 107 0.030
glucose metabolic process GO:0006006 92 0.030
positive regulation of hydrolase activity GO:0051345 148 0.030
negative regulation of protein tyrosine kinase activity GO:0061099 3 0.030
nephron tubule development GO:0072080 84 0.030
negative regulation of prostatic bud formation GO:0060686 4 0.030
multicellular organismal homeostasis GO:0048871 164 0.030
monosaccharide metabolic process GO:0005996 106 0.029
organonitrogen compound biosynthetic process GO:1901566 192 0.029
positive regulation of gtp catabolic process GO:0033126 85 0.029
regulation of stem cell proliferation GO:0072091 78 0.029
protein modification by small protein conjugation GO:0032446 187 0.029
negative regulation of leukocyte proliferation GO:0070664 46 0.029
organophosphate biosynthetic process GO:0090407 122 0.029
compound eye development GO:0048749 1 0.029
renal tubule development GO:0061326 87 0.028
mesonephros development GO:0001823 97 0.028
digestive system development GO:0055123 200 0.028
dna metabolic process GO:0006259 303 0.028
Mouse
gland development GO:0048732 330 0.028
regulation of lipid biosynthetic process GO:0046890 54 0.028
synapse organization GO:0050808 125 0.028
regulation of apoptotic signaling pathway GO:2001233 197 0.027
negative regulation of mapk cascade GO:0043409 65 0.027
sensory perception GO:0007600 245 0.027
lung development GO:0030324 164 0.027
gtp catabolic process GO:0006184 143 0.027
ion transmembrane transport GO:0034220 361 0.027
alpha beta t cell activation GO:0046631 91 0.027
chemotaxis GO:0006935 247 0.027
neuron apoptotic process GO:0051402 142 0.027
cell fate commitment GO:0045165 210 0.027
ribonucleoside triphosphate metabolic process GO:0009199 220 0.027
organic cyclic compound catabolic process GO:1901361 295 0.027
regulation of leukocyte proliferation GO:0070663 121 0.027
regulation of fat cell differentiation GO:0045598 81 0.027
inorganic cation transmembrane transport GO:0098662 207 0.026
lens morphogenesis in camera type eye GO:0002089 24 0.026
sensory system development GO:0048880 3 0.026
ribonucleoside catabolic process GO:0042454 206 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.026
asymmetric stem cell division GO:0098722 3 0.026
regulation of cellular component size GO:0032535 121 0.026
purine ribonucleotide metabolic process GO:0009150 290 0.026
cardiac muscle tissue development GO:0048738 130 0.026
embryonic appendage morphogenesis GO:0035113 126 0.026
extracellular matrix organization GO:0030198 147 0.025
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.025
neuron projection guidance GO:0097485 141 0.025
ribonucleoside triphosphate catabolic process GO:0009203 199 0.025
epithelial cell development GO:0002064 159 0.025
regulation of neural precursor cell proliferation GO:2000177 70 0.025
cell proliferation in forebrain GO:0021846 30 0.025
cellular response to biotic stimulus GO:0071216 92 0.025
embryonic epithelial tube formation GO:0001838 130 0.025
negative regulation of epidermal growth factor activated receptor activity GO:0007175 3 0.025
muscle system process GO:0003012 141 0.025
embryonic skeletal system morphogenesis GO:0048704 91 0.025
heterocycle catabolic process GO:0046700 280 0.025
leukocyte proliferation GO:0070661 172 0.025
cerebral cortex cell migration GO:0021795 44 0.024
limbic system development GO:0021761 72 0.024
cell type specific apoptotic process GO:0097285 268 0.024
branching morphogenesis of an epithelial tube GO:0048754 159 0.024
alcohol biosynthetic process GO:0046165 43 0.024
fatty acid metabolic process GO:0006631 121 0.024
actin filament organization GO:0007015 113 0.024
regulation of nucleoside metabolic process GO:0009118 130 0.024
angiogenesis GO:0001525 201 0.023
ectoderm formation GO:0001705 3 0.023
monocarboxylic acid metabolic process GO:0032787 191 0.023
regulation of secretion GO:0051046 274 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.023
negative regulation of neuron death GO:1901215 98 0.023
tyrosine phosphorylation of stat1 protein GO:0042508 3 0.023
purine containing compound metabolic process GO:0072521 311 0.023
alpha beta t cell differentiation GO:0046632 69 0.023
regulation of wnt signaling pathway GO:0030111 123 0.023
cytokine production GO:0001816 319 0.023
production of molecular mediator of immune response GO:0002440 103 0.023
gastrulation GO:0007369 116 0.023
response to growth factor GO:0070848 198 0.023
nucleotide catabolic process GO:0009166 217 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
negative regulation of response to wounding GO:1903035 77 0.022
intracellular protein transport GO:0006886 204 0.022
positive regulation of protein modification process GO:0031401 299 0.022
regulation of ras gtpase activity GO:0032318 88 0.022
hematopoietic progenitor cell differentiation GO:0002244 143 0.022
insulin receptor signaling pathway GO:0008286 49 0.022
response to organonitrogen compound GO:0010243 246 0.022
small gtpase mediated signal transduction GO:0007264 97 0.022
Rat
protein processing GO:0016485 163 0.022
positive regulation of ras gtpase activity GO:0032320 65 0.022
purine containing compound catabolic process GO:0072523 213 0.022
endocytosis GO:0006897 168 0.022
cranial nerve development GO:0021545 41 0.022
cation transport GO:0006812 399 0.022
negative regulation of neuron differentiation GO:0045665 101 0.022
guanosine containing compound metabolic process GO:1901068 144 0.022
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.022
purine nucleotide catabolic process GO:0006195 211 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
positive regulation of neuron projection development GO:0010976 79 0.021
photoreceptor cell differentiation GO:0046530 52 0.021
lymphocyte mediated immunity GO:0002449 139 0.021
positive regulation of t cell anergy GO:0002669 4 0.021
positive regulation of lymphocyte activation GO:0051251 140 0.021
response to radiation GO:0009314 165 0.021
embryonic skeletal system development GO:0048706 120 0.021
regulation of nucleotide catabolic process GO:0030811 122 0.021
neuron neuron synaptic transmission GO:0007270 69 0.021
metencephalon development GO:0022037 89 0.021
heart process GO:0003015 94 0.021
regulation of cell size GO:0008361 72 0.021
regulation of ion transmembrane transport GO:0034765 119 0.021
negative regulation of lipid metabolic process GO:0045833 30 0.021
regulation of organ growth GO:0046620 61 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.021
t cell differentiation GO:0030217 174 0.021
developmental cell growth GO:0048588 84 0.020
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.020
regulation of hydrolase activity GO:0051336 246 0.020
regulation of protein tyrosine kinase activity GO:0061097 17 0.020
myotube differentiation GO:0014902 105 0.020
ensheathment of neurons GO:0007272 76 0.020
regulation of t cell activation GO:0050863 170 0.020
membrane organization GO:0061024 245 0.020
monocarboxylic acid biosynthetic process GO:0072330 61 0.020
retina development in camera type eye GO:0060041 119 0.020
regulation of protein transport GO:0051223 163 0.020
regulation of gtp catabolic process GO:0033124 113 0.020
astrocyte differentiation GO:0048708 43 0.020
detection of stimulus GO:0051606 84 0.020
hindbrain development GO:0030902 128 0.020
negative regulation of inflammatory response GO:0050728 61 0.020
gtp metabolic process GO:0046039 144 0.019
nephron development GO:0072006 109 0.019
leukocyte mediated immunity GO:0002443 174 0.019
innate immune response GO:0045087 157 0.019
transmission of nerve impulse GO:0019226 76 0.019
interleukin 6 production GO:0032635 58 0.019
regulation of lymphocyte anergy GO:0002911 4 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.019
rho protein signal transduction GO:0007266 32 0.019
cellular response to lipopolysaccharide GO:0071222 77 0.019
engulfment of apoptotic cell GO:0043652 3 0.019
positive regulation of transferase activity GO:0051347 167 0.019
carbohydrate biosynthetic process GO:0016051 74 0.019
glucose homeostasis GO:0042593 128 0.019
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.019
tube closure GO:0060606 91 0.018
glycoprotein metabolic process GO:0009100 116 0.018
positive regulation of rho gtpase activity GO:0032321 41 0.018
ubiquitin dependent protein catabolic process GO:0006511 129 0.018
nucleobase containing small molecule metabolic process GO:0055086 352 0.018
positive regulation of mapk cascade GO:0043410 170 0.018
sensory perception of mechanical stimulus GO:0050954 107 0.018
positive regulation of cell projection organization GO:0031346 95 0.018
positive regulation of protein catabolic process GO:0045732 60 0.018
forebrain neuron differentiation GO:0021879 52 0.018
regulation of t cell anergy GO:0002667 4 0.018
prostate gland development GO:0030850 48 0.018
negative regulation of cell migration GO:0030336 59 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.018
positive regulation of defense response GO:0031349 124 0.018
multicellular organismal signaling GO:0035637 91 0.018
negative regulation of lymphocyte proliferation GO:0050672 45 0.018
blood circulation GO:0008015 195 0.018
modification dependent protein catabolic process GO:0019941 133 0.018
generation of precursor metabolites and energy GO:0006091 103 0.018
lipid modification GO:0030258 65 0.018
regulation of erk1 and erk2 cascade GO:0070372 71 0.018
cardiac chamber morphogenesis GO:0003206 93 0.018
polarity specification of proximal distal axis GO:0010085 2 0.018
response to acid chemical GO:0001101 111 0.018
negative regulation of axon extension GO:0030517 19 0.018
regulation of asymmetric cell division GO:0009786 4 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
molting cycle GO:0042303 90 0.017
cardiac ventricle development GO:0003231 83 0.017
positive regulation of leukocyte proliferation GO:0070665 73 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.017
hippocampus development GO:0021766 52 0.017
tendon cell differentiation GO:0035990 4 0.017
regulation of receptor activity GO:0010469 41 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.017
response to monosaccharide GO:0034284 67 0.017
neural tube closure GO:0001843 90 0.017
b cell mediated immunity GO:0019724 71 0.017
cellular response to molecule of bacterial origin GO:0071219 83 0.017
hormone metabolic process GO:0042445 86 0.017
histone modification GO:0016570 159 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
positive regulation of lymphocyte anergy GO:0002913 4 0.017
cardiac chamber development GO:0003205 108 0.017
peptidyl serine modification GO:0018209 83 0.017
cell growth GO:0016049 130 0.017
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.017
mitochondrion organization GO:0007005 134 0.017
forebrain generation of neurons GO:0021872 63 0.017
positive regulation of cell division GO:0051781 31 0.017
Mouse
adaptive immune response GO:0002250 155 0.017
cell differentiation in spinal cord GO:0021515 53 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
proteoglycan metabolic process GO:0006029 38 0.017
regulation of tyrosine phosphorylation of stat1 protein GO:0042510 2 0.017
chromatin modification GO:0016568 187 0.017
spermatid development GO:0007286 108 0.017
biomineral tissue development GO:0031214 64 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
replacement ossification GO:0036075 26 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
regulation of rho gtpase activity GO:0032319 58 0.016
regulation of neuron apoptotic process GO:0043523 122 0.016
immune effector process GO:0002252 321 0.016
embryonic placenta development GO:0001892 98 0.016
innervation GO:0060384 22 0.016
adult behavior GO:0030534 135 0.016
male sex differentiation GO:0046661 109 0.016
regulation of cell motility GO:2000145 236 0.016
negative regulation of neuron apoptotic process GO:0043524 92 0.016
neural precursor cell proliferation GO:0061351 121 0.016
rhythmic process GO:0048511 174 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
branching involved in salivary gland morphogenesis GO:0060445 26 0.016
nucleoside metabolic process GO:0009116 246 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
extracellular structure organization GO:0043062 148 0.016
kidney morphogenesis GO:0060993 83 0.016
placenta development GO:0001890 140 0.016
negative regulation of neuron projection development GO:0010977 50 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
b cell proliferation GO:0042100 53 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
regulation of myeloid cell differentiation GO:0045637 96 0.016
carbohydrate homeostasis GO:0033500 128 0.016
regulation of organ formation GO:0003156 34 0.015
defense response to other organism GO:0098542 197 0.015
ear morphogenesis GO:0042471 118 0.015
glycerophospholipid metabolic process GO:0006650 71 0.015
cellular component assembly involved in morphogenesis GO:0010927 139 0.015
heart growth GO:0060419 45 0.015
morphogenesis of a branching epithelium GO:0061138 193 0.015
regulation of map kinase activity GO:0043405 120 0.015
jak stat cascade GO:0007259 42 0.015
cellular response to abiotic stimulus GO:0071214 56 0.015
spinal cord development GO:0021510 81 0.015
ureteric bud morphogenesis GO:0060675 62 0.015
cellularization GO:0007349 1 0.015
regulation of smoothened signaling pathway GO:0008589 58 0.015
negative regulation of cell projection organization GO:0031345 56 0.015
nuclear division GO:0000280 158 0.015
Mouse
metanephric loop of henle development GO:0072236 4 0.015
positive regulation of b cell activation GO:0050871 49 0.015
female gonad development GO:0008585 71 0.015
detection of molecule of bacterial origin GO:0032490 2 0.015
regulation of cellular response to stress GO:0080135 159 0.015
circulatory system process GO:0003013 197 0.015
response to extracellular stimulus GO:0009991 127 0.015
blood vessel morphogenesis GO:0048514 285 0.015
cell differentiation involved in kidney development GO:0061005 33 0.015
regulation of cell migration GO:0030334 219 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
cognition GO:0050890 149 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
mesenchymal cell development GO:0014031 93 0.015
retina morphogenesis in camera type eye GO:0060042 45 0.015
tissue homeostasis GO:0001894 115 0.015
regulation of kidney development GO:0090183 40 0.015
glycerolipid biosynthetic process GO:0045017 50 0.015
positive regulation of osteoblast differentiation GO:0045669 34 0.015
regulation of multi organism process GO:0043900 111 0.015
cardiac septum development GO:0003279 59 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
positive regulation of secretion by cell GO:1903532 114 0.014
establishment of protein localization to membrane GO:0090150 54 0.014
regulation of homeostatic process GO:0032844 182 0.014
dendrite development GO:0016358 115 0.014
skeletal muscle organ development GO:0060538 163 0.014
anatomical structure homeostasis GO:0060249 145 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.014
anion transport GO:0006820 177 0.014
immunoglobulin mediated immune response GO:0016064 69 0.014
regulation of embryonic development GO:0045995 71 0.014
outflow tract morphogenesis GO:0003151 53 0.014
tendon formation GO:0035992 4 0.014
regulation of response to wounding GO:1903034 189 0.014
t cell anergy GO:0002870 4 0.014

Sh2b2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
disease of metabolism DOID:0014667 0 0.020
bone disease DOID:0080001 0 0.016
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.016
osteochondrodysplasia DOID:2256 0 0.016
bone development disease DOID:0080006 0 0.016
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014