Mus musculus

24 known processes

Ube2d3

ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)

(Aliases: 1100001F19Rik,AA414951,9430029A22Rik)

Ube2d3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein polyubiquitination GO:0000209 33 0.916
Yeast Mouse
endoplasmic reticulum tubular network organization GO:0071786 1 0.873
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.717
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.593
protein modification by small protein conjugation or removal GO:0070647 207 0.587
Yeast Mouse Rat
cellular protein catabolic process GO:0044257 155 0.566
regulation of cellular catabolic process GO:0031329 242 0.532
proteasomal protein catabolic process GO:0010498 98 0.527
polyamine transport GO:0015846 5 0.503
modification dependent protein catabolic process GO:0019941 133 0.477
macromolecule catabolic process GO:0009057 281 0.415
modification dependent macromolecule catabolic process GO:0043632 133 0.384
endoplasmic reticulum organization GO:0007029 10 0.382
ras protein signal transduction GO:0007265 77 0.324
regulation of protein catabolic process GO:0042176 108 0.323
protein catabolic process GO:0030163 221 0.292
ribonucleoside triphosphate catabolic process GO:0009203 199 0.260
protein modification by small protein conjugation GO:0032446 187 0.233
Yeast Mouse Rat
regulation of mitochondrion organization GO:0010821 27 0.222
guanosine containing compound metabolic process GO:1901068 144 0.218
organic cyclic compound catabolic process GO:1901361 295 0.209
heterocycle catabolic process GO:0046700 280 0.199
purine ribonucleotide catabolic process GO:0009154 208 0.199
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.197
regulation of polyamine transmembrane transport GO:1902267 5 0.184
gtp metabolic process GO:0046039 144 0.183
negative regulation of cellular component organization GO:0051129 194 0.173
regulation of mitochondrial fission GO:0090140 3 0.171
cellular macromolecule catabolic process GO:0044265 206 0.171
purine containing compound catabolic process GO:0072523 213 0.170
regulation of organelle organization GO:0033043 289 0.164
purine nucleoside catabolic process GO:0006152 205 0.162
ribonucleoside catabolic process GO:0042454 206 0.161
regulation of apoptotic signaling pathway GO:2001233 197 0.152
nucleoside phosphate catabolic process GO:1901292 222 0.152
centrosome separation GO:0051299 4 0.151
endomembrane system organization GO:0010256 147 0.147
regulation of cellular component biogenesis GO:0044087 181 0.144
ubiquitin dependent protein catabolic process GO:0006511 129 0.141
cellular amine metabolic process GO:0044106 44 0.135
positive regulation of cellular catabolic process GO:0031331 148 0.127
protein ubiquitination GO:0016567 171 0.123
Yeast Mouse Rat
spermatid development GO:0007286 108 0.119
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.112
spermatogenesis GO:0007283 284 0.111
regulation of cellular response to stress GO:0080135 159 0.107
nucleoside metabolic process GO:0009116 246 0.103
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.099
intrinsic apoptotic signaling pathway GO:0097193 132 0.098
purine nucleotide catabolic process GO:0006195 211 0.096
regulation of protein localization GO:0032880 231 0.095
response to light stimulus GO:0009416 135 0.095
aromatic compound catabolic process GO:0019439 286 0.092
polyamine biosynthetic process GO:0006596 2 0.090
cellularization GO:0007349 1 0.088
regulation of cellular protein catabolic process GO:1903362 61 0.083
protein localization to organelle GO:0033365 185 0.083
nucleotide metabolic process GO:0009117 332 0.082
regulation of neurotransmitter levels GO:0001505 87 0.079
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.079
apoptotic signaling pathway GO:0097190 306 0.079
regulation of secretion GO:0051046 274 0.076
germ cell development GO:0007281 185 0.074
nucleotide catabolic process GO:0009166 217 0.074
transmembrane transport GO:0055085 412 0.072
regulation of mapk cascade GO:0043408 248 0.071
cellular nitrogen compound catabolic process GO:0044270 280 0.070
protein k48 linked ubiquitination GO:0070936 7 0.070
negative regulation of intracellular signal transduction GO:1902532 167 0.069
negative regulation of synaptic vesicle exocytosis GO:2000301 3 0.068
vesicle localization GO:0051648 86 0.067
small gtpase mediated signal transduction GO:0007264 97 0.066
purine ribonucleoside metabolic process GO:0046128 241 0.062
establishment of vesicle localization GO:0051650 81 0.062
amine metabolic process GO:0009308 45 0.062
regulation of cell migration GO:0030334 219 0.062
regulation of cell motility GO:2000145 236 0.060
nucleobase containing small molecule metabolic process GO:0055086 352 0.060
nicotinamide nucleotide biosynthetic process GO:0019359 4 0.059
regulation of secretion by cell GO:1903530 249 0.059
organelle fission GO:0048285 170 0.057
purine nucleoside triphosphate catabolic process GO:0009146 203 0.056
canonical wnt signaling pathway GO:0060070 130 0.056
nucleoside catabolic process GO:0009164 206 0.056
establishment of organelle localization GO:0051656 122 0.056
chromosome segregation GO:0007059 48 0.056
cellular amino acid metabolic process GO:0006520 103 0.055
carbohydrate derivative catabolic process GO:1901136 231 0.054
organelle localization GO:0051640 179 0.053
intracellular receptor signaling pathway GO:0030522 74 0.053
purine containing compound metabolic process GO:0072521 311 0.052
cellular response to dna damage stimulus GO:0006974 207 0.052
male gamete generation GO:0048232 285 0.051
regulation of cytoplasmic transport GO:1903649 112 0.051
stem cell differentiation GO:0048863 268 0.050
glycosyl compound metabolic process GO:1901657 246 0.050
ribonucleotide catabolic process GO:0009261 208 0.050
nitrogen compound transport GO:0071705 271 0.048
regionalization GO:0003002 337 0.048
nucleoside phosphate metabolic process GO:0006753 338 0.048
cytoplasmic transport GO:0016482 234 0.048
ossification GO:0001503 216 0.046
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.046
positive regulation of secretion by cell GO:1903532 114 0.045
regulation of neuron differentiation GO:0045664 281 0.045
purine ribonucleotide metabolic process GO:0009150 290 0.045
ribonucleoside metabolic process GO:0009119 245 0.045
establishment of synaptic vesicle localization GO:0097480 57 0.043
regulation of proteolysis GO:0030162 164 0.042
positive regulation of meiosis i GO:0060903 5 0.042
multicellular organismal macromolecule catabolic process GO:0044266 1 0.042
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.040
regulation of anatomical structure size GO:0090066 178 0.040
protein neddylation GO:0045116 1 0.040
regulation of transferase activity GO:0051338 263 0.040
intracellular protein transport GO:0006886 204 0.040
positive regulation of cellular protein catabolic process GO:1903364 34 0.039
purine nucleotide metabolic process GO:0006163 302 0.039
mrna processing GO:0006397 63 0.039
regulation of multi organism process GO:0043900 111 0.038
nucleoside triphosphate metabolic process GO:0009141 230 0.038
multicellular organismal protein metabolic process GO:0044268 2 0.037
negative regulation of cell motility GO:2000146 61 0.037
cell adhesion GO:0007155 329 0.037
localization within membrane GO:0051668 4 0.037
polyamine transmembrane transport GO:1902047 5 0.037
organonitrogen compound catabolic process GO:1901565 264 0.036
cellular response to organonitrogen compound GO:0071417 145 0.036
glycosyl compound catabolic process GO:1901658 206 0.036
circadian regulation of gene expression GO:0032922 48 0.036
regulation of system process GO:0044057 200 0.036
regulation of protein complex assembly GO:0043254 83 0.036
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.035
protein complex disassembly GO:0043241 40 0.034
positive regulation of secretion GO:0051047 130 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.034
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.034
meiotic cell cycle process GO:1903046 77 0.033
mesenchyme development GO:0060485 152 0.033
neurotransmitter transport GO:0006836 76 0.032
regulation of mrna processing GO:0050684 41 0.032
multi organism behavior GO:0051705 62 0.032
postreplication repair GO:0006301 5 0.032
membrane organization GO:0061024 245 0.032
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.031
macromolecular complex disassembly GO:0032984 43 0.031
negative regulation of organelle organization GO:0010639 90 0.031
transmission of nerve impulse GO:0019226 76 0.030
regulation of intracellular transport GO:0032386 159 0.030
purine ribonucleoside catabolic process GO:0046130 205 0.030
lamellipodium organization GO:0097581 29 0.030
positive regulation of mapk cascade GO:0043410 170 0.029
single organism cell adhesion GO:0098602 156 0.029
synapse assembly GO:0007416 56 0.029
negative regulation of synaptic vesicle transport GO:1902804 3 0.029
regulation of cellular component size GO:0032535 121 0.029
translesion synthesis GO:0019985 1 0.029
mitotic cell cycle GO:0000278 195 0.029
rhythmic process GO:0048511 174 0.029
golgi vesicle transport GO:0048193 30 0.029
synaptic vesicle transport GO:0048489 57 0.028
organophosphate catabolic process GO:0046434 232 0.028
defense response to other organism GO:0098542 197 0.028
organic hydroxy compound metabolic process GO:1901615 203 0.027
nucleoside triphosphate catabolic process GO:0009143 205 0.027
regulation of vacuole organization GO:0044088 4 0.027
membrane lipid metabolic process GO:0006643 53 0.027
response to inorganic substance GO:0010035 96 0.027
mrna metabolic process GO:0016071 84 0.026
regulation of establishment of protein localization GO:0070201 181 0.026
chondrocyte hypertrophy GO:0003415 4 0.026
positive regulation of proteolysis GO:0045862 85 0.026
regulation of protein transport GO:0051223 163 0.026
positive regulation of mitochondrial fission GO:0090141 2 0.026
purine nucleoside metabolic process GO:0042278 241 0.026
regulation of ras protein signal transduction GO:0046578 114 0.026
gtp catabolic process GO:0006184 143 0.026
regulation of nucleotide catabolic process GO:0030811 122 0.025
response to organonitrogen compound GO:0010243 246 0.025
dna metabolic process GO:0006259 303 0.025
positive regulation of protein transport GO:0051222 93 0.025
ribose phosphate metabolic process GO:0019693 291 0.025
positive regulation of protein modification process GO:0031401 299 0.025
regulation of cell shape GO:0008360 39 0.025
developmental cell growth GO:0048588 84 0.024
striated muscle tissue development GO:0014706 293 0.024
regulation of mitotic cell cycle GO:0007346 126 0.024
multi multicellular organism process GO:0044706 109 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
synapse organization GO:0050808 125 0.024
muscle tissue development GO:0060537 308 0.024
regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902253 13 0.024
rna processing GO:0006396 105 0.023
regulation of cytoskeleton organization GO:0051493 122 0.023
response to radiation GO:0009314 165 0.023
hindbrain development GO:0030902 128 0.022
dna templated transcription termination GO:0006353 4 0.022
circulatory system process GO:0003013 197 0.022
copii coated vesicle budding GO:0090114 2 0.022
synaptic transmission GO:0007268 329 0.022
sphingolipid metabolic process GO:0006665 45 0.022
establishment or maintenance of cell polarity GO:0007163 86 0.022
cell junction maintenance GO:0034331 4 0.022
mapk cascade GO:0000165 281 0.022
oocyte anterior posterior axis specification GO:0007314 2 0.021
mesoderm development GO:0007498 100 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
retrograde transport vesicle recycling within golgi GO:0000301 1 0.021
positive regulation of gtpase activity GO:0043547 85 0.021
regulation of mrna splicing via spliceosome GO:0048024 32 0.021
negative regulation of nervous system development GO:0051961 156 0.021
positive regulation of protein kinase activity GO:0045860 144 0.021
synaptic vesicle localization GO:0097479 59 0.021
regulation of protein autophosphorylation GO:0031952 8 0.021
membrane fusion GO:0061025 38 0.020
positive regulation of cell cycle GO:0045787 92 0.020
negative regulation of protein metabolic process GO:0051248 282 0.020
positive regulation of cell development GO:0010720 237 0.020
regulation of hormone levels GO:0010817 211 0.020
positive regulation of neuron differentiation GO:0045666 141 0.020
multicellular organismal protein catabolic process GO:0044254 1 0.020
peptide hormone secretion GO:0030072 109 0.020
microtubule organizing center organization GO:0031023 28 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
regulation of epithelial cell proliferation GO:0050678 141 0.020
ribonucleotide metabolic process GO:0009259 291 0.019
mitochondrion distribution GO:0048311 4 0.019
polyamine metabolic process GO:0006595 5 0.019
lung development GO:0030324 164 0.019
protein secretion GO:0009306 111 0.019
maintenance of apical basal cell polarity GO:0035090 3 0.019
regulation of rna splicing GO:0043484 37 0.019
chromatin organization GO:0006325 206 0.019
peptidyl tyrosine modification GO:0018212 145 0.019
barbed end actin filament capping GO:0051016 6 0.019
regulation of hydrolase activity GO:0051336 246 0.019
organelle assembly GO:0070925 177 0.018
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.018
positive regulation of transferase activity GO:0051347 167 0.018
regulation of defense response GO:0031347 233 0.018
positive regulation of protein catabolic process GO:0045732 60 0.018
positive regulation of organelle organization GO:0010638 128 0.018
positive regulation of nervous system development GO:0051962 221 0.018
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.018
regulation of transmembrane transport GO:0034762 128 0.018
dna repair GO:0006281 107 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
amide transport GO:0042886 138 0.018
protein localization to cell leading edge GO:1902463 1 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
double strand break repair via homologous recombination GO:0000724 21 0.017
meiosis i GO:0007127 60 0.017
protein digestion GO:0044256 1 0.017
segmentation GO:0035282 93 0.017
toxin transport GO:1901998 38 0.017
hormone secretion GO:0046879 128 0.017
epithelial cell proliferation GO:0050673 174 0.017
maintenance of location GO:0051235 89 0.017
cation transport GO:0006812 399 0.017
lateral inhibition GO:0046331 1 0.016
regulation of cellular amine metabolic process GO:0033238 20 0.016
spermatid differentiation GO:0048515 115 0.016
positive regulation of protein autophosphorylation GO:0031954 4 0.016
chromatin modification GO:0016568 187 0.016
protein localization to membrane GO:0072657 108 0.016
peptidyl tyrosine phosphorylation GO:0018108 143 0.016
mrna splicing via spliceosome GO:0000398 43 0.016
neuron projection extension GO:1990138 64 0.016
glycoprotein biosynthetic process GO:0009101 89 0.016
cellular lipid metabolic process GO:0044255 323 0.016
rna splicing via transesterification reactions GO:0000375 43 0.016
metaphase plate congression GO:0051310 2 0.016
positive regulation of vasculogenesis GO:2001214 7 0.016
regulation of cellular response to growth factor stimulus GO:0090287 82 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
stress activated protein kinase signaling cascade GO:0031098 81 0.015
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.015
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.015
regulation of ran protein signal transduction GO:0032015 3 0.015
regulation of glycogen catabolic process GO:0005981 2 0.015
cellular response to inorganic substance GO:0071241 37 0.015
establishment of melanosome localization GO:0032401 11 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
positive regulation of mrna metabolic process GO:1903313 17 0.015
positive regulation of meiotic cell cycle GO:0051446 15 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
trophectodermal cellular morphogenesis GO:0001831 3 0.014
regulation of mrna metabolic process GO:1903311 43 0.014
regulation of purine nucleotide catabolic process GO:0033121 122 0.014
divalent inorganic cation transport GO:0072511 178 0.014
regulation of protein import into nucleus GO:0042306 52 0.014
regulation of intracellular protein transport GO:0033157 82 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.014
negative regulation of cell development GO:0010721 169 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
regulation of cell growth GO:0001558 91 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
negative regulation of synapse assembly GO:0051964 3 0.014
regulation of peptide transport GO:0090087 91 0.014
regulation of cellular ketone metabolic process GO:0010565 66 0.014
pole plasm assembly GO:0007315 2 0.014
positive regulation of cell death GO:0010942 224 0.014
axon target recognition GO:0007412 4 0.014
protein oligomerization GO:0051259 67 0.014
inorganic ion transmembrane transport GO:0098660 234 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.013
reproductive behavior GO:0019098 32 0.013
microtubule based process GO:0007017 236 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.013
regulation of neural precursor cell proliferation GO:2000177 70 0.013
respiratory system development GO:0060541 190 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
ion transmembrane transport GO:0034220 361 0.013
maternal process involved in female pregnancy GO:0060135 32 0.013
protein polymerization GO:0051258 57 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
positive regulation of hormone secretion GO:0046887 38 0.013
regulation of protein kinase activity GO:0045859 232 0.013
peptide secretion GO:0002790 114 0.013
multicellular organismal reproductive behavior GO:0033057 23 0.013
protein localization to plasma membrane GO:0072659 57 0.013
exocytosis GO:0006887 121 0.013
er associated ubiquitin dependent protein catabolic process GO:0030433 10 0.013
response to uv GO:0009411 44 0.013
regulation of proteasomal protein catabolic process GO:0061136 46 0.013
positive regulation of cell motility GO:2000147 116 0.012
positive regulation of peptide secretion GO:0002793 33 0.012
glycoprotein metabolic process GO:0009100 116 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.012
peptide transport GO:0015833 133 0.012
actin cytoskeleton organization GO:0030036 220 0.012
regulation of er to golgi vesicle mediated transport GO:0060628 4 0.012
negative regulation of protein catabolic process GO:0042177 36 0.012
somite development GO:0061053 81 0.012
metencephalon development GO:0022037 89 0.012
nucleus localization GO:0051647 20 0.012
asymmetric neuroblast division GO:0055059 1 0.012
epithelial cell development GO:0002064 159 0.012
stem cell development GO:0048864 219 0.012
erk1 and erk2 cascade GO:0070371 77 0.012
cell cell junction organization GO:0045216 72 0.012
regulation of cell cycle process GO:0010564 160 0.012
regulation of kinase activity GO:0043549 249 0.012
locomotory behavior GO:0007626 195 0.012
amp metabolic process GO:0046033 4 0.012
regulation of response to dna damage stimulus GO:2001020 34 0.012
carbohydrate homeostasis GO:0033500 128 0.012
vesicle coating GO:0006901 2 0.012
female gamete generation GO:0007292 74 0.012
oogenesis GO:0048477 56 0.012
maintenance of epithelial cell apical basal polarity GO:0045199 2 0.011
cytokinesis GO:0000910 17 0.011
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.011
innate immune response GO:0045087 157 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
protein k63 linked ubiquitination GO:0070534 6 0.011
glucose homeostasis GO:0042593 128 0.011
immune response in mucosal associated lymphoid tissue GO:0002386 2 0.011
regulation of protein ubiquitination GO:0031396 52 0.011
regulation of cell projection organization GO:0031344 206 0.011
cellular response to monosaccharide stimulus GO:0071326 47 0.011
respiratory tube development GO:0030323 167 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
regulation of cell adhesion GO:0030155 154 0.011
actin polymerization or depolymerization GO:0008154 54 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
positive regulation of cellular amine metabolic process GO:0033240 5 0.011
neuron migration GO:0001764 122 0.011
regulation of actin filament based process GO:0032970 99 0.011
positive regulation of nuclear division GO:0051785 27 0.010
regulation of reproductive process GO:2000241 66 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
pyridine nucleotide biosynthetic process GO:0019363 4 0.010
regulation of cellular amino acid metabolic process GO:0006521 5 0.010
cellular ketone metabolic process GO:0042180 84 0.010
endothelium development GO:0003158 45 0.010
regulation of embryonic development GO:0045995 71 0.010
regulation of hormone secretion GO:0046883 88 0.010
mesenchymal cell differentiation GO:0048762 107 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
dna recombination GO:0006310 92 0.010
leukocyte cell cell adhesion GO:0007159 14 0.010
response to metal ion GO:0010038 47 0.010
harderian gland development GO:0070384 2 0.010
negative regulation of intracellular transport GO:0032387 38 0.010

Ube2d3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.013
disease of mental health DOID:150 0 0.012
disease of anatomical entity DOID:7 0 0.011
musculoskeletal system disease DOID:17 0 0.011