|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.523
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.459
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.383
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.356
|
Fly |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.345
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.327
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.317
|
|
|
|
photoreceptor cell development
|
GO:0042461 |
40 |
0.314
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.313
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.304
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.304
|
Fly |
|
|
skin development
|
GO:0043588 |
220 |
0.304
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.304
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.285
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.272
|
|
|
|
cilium assembly
|
GO:0042384 |
81 |
0.264
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.258
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.249
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.243
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.238
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.237
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.236
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.234
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.231
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.231
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.231
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.227
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.220
|
|
|
|
photoreceptor cell morphogenesis
|
GO:0008594 |
3 |
0.220
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.213
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.213
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.211
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.208
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.206
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.204
|
|
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.203
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.200
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.197
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.194
|
Fly |
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.191
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.188
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.188
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.187
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.186
|
|
|
|
macroautophagy
|
GO:0016236 |
21 |
0.186
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.186
|
|
|
|
regulation of autophagy
|
GO:0010506 |
30 |
0.184
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.183
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.183
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.183
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
102 |
0.179
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.178
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.177
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.176
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.175
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.174
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.174
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.172
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.172
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.171
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.171
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.171
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.169
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.168
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.167
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.163
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.162
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.162
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.153
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.152
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.150
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.147
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.143
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.143
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.143
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.143
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.142
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.141
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.141
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.140
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.139
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.139
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.139
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.138
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.136
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.136
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.136
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.136
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.135
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.133
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.129
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.127
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.127
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.127
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.127
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.125
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.125
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.124
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.124
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.124
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.124
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.123
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.122
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.122
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.121
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.121
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.121
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.120
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.120
|
Fly |
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.119
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.119
|
|
|
|
hippo signaling
|
GO:0035329 |
11 |
0.119
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.118
|
|
|
|
regulation of organ growth
|
GO:0046620 |
61 |
0.117
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.117
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.116
|
|
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.115
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.112
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.111
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.110
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.109
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.109
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.109
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.109
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.109
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.108
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.107
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.107
|
Fly |
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.106
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.106
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.105
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.105
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.105
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.105
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.105
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.103
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.103
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.103
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.102
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.101
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.101
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.101
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.100
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.100
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.100
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.100
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.099
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.099
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.098
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.098
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.098
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.098
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.097
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.097
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.097
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.097
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.096
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.096
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.095
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.095
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.094
|
Fly |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.094
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.094
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.093
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.093
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.092
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.092
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.092
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.092
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.091
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.091
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.091
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.091
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.090
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.090
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.090
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.090
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.089
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.089
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.089
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.089
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.089
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.088
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.088
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.088
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.087
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.086
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.086
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.085
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.085
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.085
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.085
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.085
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.084
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.084
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.084
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.083
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.082
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.082
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.081
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.081
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.081
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.080
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.080
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.080
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.079
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.079
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.079
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.079
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.078
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.078
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.077
|
Fly |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.077
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.076
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.076
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.076
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.076
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.075
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.075
|
|
|
|
renal tubule development
|
GO:0061326 |
87 |
0.075
|
Fly |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.074
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.073
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.073
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.073
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.073
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.072
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.072
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.071
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.071
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.071
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.071
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
23 |
0.070
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.070
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.070
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.070
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
16 |
0.070
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.069
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.069
|
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.068
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.067
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.067
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.067
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.067
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.066
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.066
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.066
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.066
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.066
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.066
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.066
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.065
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.065
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.065
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.065
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.065
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.065
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.064
|
Fly |
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.064
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.064
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.064
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.063
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.063
|
|
|
|
response to starvation
|
GO:0042594 |
65 |
0.062
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.062
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.062
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.061
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.061
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.061
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.061
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.061
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.060
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
53 |
0.060
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.060
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.059
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.059
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.058
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.058
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.058
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.058
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
17 |
0.057
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.057
|
Fly |
|
|
protein maturation
|
GO:0051604 |
176 |
0.057
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.057
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.057
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.056
|
Fly |
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.056
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.056
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.056
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.056
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.056
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.055
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.055
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.055
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.055
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.055
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.055
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
51 |
0.055
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.055
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.054
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.054
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.054
|
|
|
|
lung morphogenesis
|
GO:0060425 |
50 |
0.054
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.053
|
|
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
32 |
0.053
|
|
|
|
nephron tubule development
|
GO:0072080 |
84 |
0.053
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.053
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.053
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.052
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.052
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.052
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.052
|
Fly |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.052
|
|
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
3 |
0.052
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.052
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.051
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.051
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.051
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.051
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.050
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.050
|
|
|
|
nephron epithelium development
|
GO:0072009 |
92 |
0.050
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.050
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.049
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.049
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.049
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.049
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.049
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.049
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.049
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.049
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.049
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.049
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.049
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.049
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.048
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.048
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.048
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.048
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.048
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.048
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.048
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.047
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.047
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.047
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.047
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.047
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.047
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.046
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.046
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.046
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.046
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.046
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.046
|
Fly |
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.046
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.046
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.046
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.046
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.045
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.045
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.045
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.045
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.045
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.045
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
47 |
0.045
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.045
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.045
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.044
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.044
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.044
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.044
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.044
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.044
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.044
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
21 |
0.043
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.043
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.043
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.043
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.043
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.043
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.043
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.043
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.042
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
41 |
0.042
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.042
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.042
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.042
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.042
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.042
|
|
|
|
glycosylation
|
GO:0070085 |
62 |
0.042
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.041
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.041
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.041
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.041
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.041
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.041
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.041
|
|
|
|
cell fate specification
|
GO:0001708 |
72 |
0.041
|
Fly |
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.040
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.040
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.040
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.040
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.040
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.039
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.039
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.039
|
|
|
|
female meiosis chromosome segregation
|
GO:0016321 |
1 |
0.039
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
21 |
0.039
|
|
|
|
mesonephric tubule morphogenesis
|
GO:0072171 |
63 |
0.039
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.039
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.039
|
|
|
|
inter male aggressive behavior
|
GO:0002121 |
3 |
0.039
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.039
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.039
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.038
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.038
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.038
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.038
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.038
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.038
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.038
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.037
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.037
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.037
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.037
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.037
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.037
|
|
|
|
cell differentiation involved in embryonic placenta development
|
GO:0060706 |
26 |
0.037
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.037
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.037
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.037
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.037
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.037
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.037
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.036
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.036
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.036
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.036
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.036
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.036
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.036
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.036
|
|
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.035
|
|
|
|
negative regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045736 |
9 |
0.035
|
|
|
|
spleen development
|
GO:0048536 |
39 |
0.035
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.035
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.035
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.035
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.035
|
|
|
|
cellular response to nitric oxide
|
GO:0071732 |
4 |
0.035
|
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
4 |
0.035
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.035
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.035
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.035
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
25 |
0.035
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.034
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.034
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.034
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.034
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.034
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.034
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.034
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.034
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
40 |
0.034
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.034
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.034
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.034
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.033
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.033
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.033
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.033
|
|
|
|
inner ear receptor cell differentiation
|
GO:0060113 |
61 |
0.033
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.033
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.033
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.033
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.033
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.033
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.032
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.032
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.032
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.032
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
31 |
0.032
|
|
|
|
regulation of gliogenesis
|
GO:0014013 |
50 |
0.032
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.032
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.032
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.032
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.032
|
|
|
|
positive regulation of rac protein signal transduction
|
GO:0035022 |
1 |
0.032
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.032
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.032
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.032
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.031
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.031
|
|
