Mus musculus

0 known processes

Cul9

cullin 9

(Aliases: 1810035I07Rik,Parc,mKIAA0708)

Cul9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of protein modification process GO:0031400 163 0.148
histone h3 k9 acetylation GO:0043970 5 0.129
negative regulation of cellular protein metabolic process GO:0032269 247 0.123
regulation of organelle organization GO:0033043 289 0.114
Human
negative regulation of molecular function GO:0044092 258 0.105
regulation of hydrolase activity GO:0051336 246 0.097
regulation of transferase activity GO:0051338 263 0.090
histone modification GO:0016570 159 0.088
negative regulation of kinase activity GO:0033673 81 0.080
regulation of mapk cascade GO:0043408 248 0.079
negative regulation of protein metabolic process GO:0051248 282 0.073
covalent chromatin modification GO:0016569 163 0.066
negative regulation of intracellular signal transduction GO:1902532 167 0.062
locomotory behavior GO:0007626 195 0.062
negative regulation of phospholipase activity GO:0010519 4 0.061
regulation of cell cycle process GO:0010564 160 0.057
Human
mapk cascade GO:0000165 281 0.055
negative regulation of phosphate metabolic process GO:0045936 184 0.054
regulation of chromosome organization GO:0033044 83 0.054
cation transport GO:0006812 399 0.053
chromatin modification GO:0016568 187 0.053
nucleobase containing small molecule metabolic process GO:0055086 352 0.053
negative regulation of protein phosphorylation GO:0001933 126 0.052
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.051
dna metabolic process GO:0006259 303 0.049
cation transmembrane transport GO:0098655 266 0.048
histone lysine demethylation GO:0070076 13 0.048
positive regulation of organelle organization GO:0010638 128 0.048
ribose phosphate metabolic process GO:0019693 291 0.047
negative regulation of phosphorus metabolic process GO:0010563 184 0.045
male gamete generation GO:0048232 285 0.045
negative regulation of camp mediated signaling GO:0043951 3 0.045
cellular ketone metabolic process GO:0042180 84 0.043
g protein coupled receptor signaling pathway GO:0007186 243 0.043
negative regulation of cellular component organization GO:0051129 194 0.043
muscle system process GO:0003012 141 0.042
chromatin organization GO:0006325 206 0.042
negative regulation of hydrolase activity GO:0051346 71 0.041
regulation of adrenergic receptor signaling pathway GO:0071877 4 0.041
macromolecule deacylation GO:0098732 37 0.041
regulation of histone modification GO:0031056 56 0.040
transmembrane transport GO:0055085 412 0.040
ion transmembrane transport GO:0034220 361 0.040
protein demethylation GO:0006482 13 0.039
adrenergic receptor signaling pathway GO:0071875 13 0.038
dna repair GO:0006281 107 0.038
peptidyl amino acid modification GO:0018193 336 0.038
regulation of chromatin organization GO:1902275 57 0.037
inorganic ion transmembrane transport GO:0098660 234 0.037
positive regulation of protein modification process GO:0031401 299 0.037
cellular amino acid metabolic process GO:0006520 103 0.037
regulation of membrane potential GO:0042391 192 0.037
regulation of chromatin modification GO:1903308 57 0.036
regulation of cellular ketone metabolic process GO:0010565 66 0.034
regulation of cellular amino acid metabolic process GO:0006521 5 0.034
purine containing compound metabolic process GO:0072521 311 0.034
positive regulation of hydrolase activity GO:0051345 148 0.033
rhythmic process GO:0048511 174 0.033
purine nucleoside metabolic process GO:0042278 241 0.033
cellular amine metabolic process GO:0044106 44 0.033
protein acylation GO:0043543 64 0.032
protein dealkylation GO:0008214 13 0.032
embryonic organ morphogenesis GO:0048562 276 0.032
positive regulation of mapk cascade GO:0043410 170 0.032
internal protein amino acid acetylation GO:0006475 42 0.032
fat cell differentiation GO:0045444 160 0.031
regulation of anatomical structure size GO:0090066 178 0.031
circadian regulation of gene expression GO:0032922 48 0.031
response to growth factor GO:0070848 198 0.031
histone demethylation GO:0016577 13 0.031
negative regulation of transferase activity GO:0051348 85 0.030
protein deacetylation GO:0006476 32 0.030
negative regulation of osteoblast differentiation GO:0045668 30 0.030
mitotic cell cycle GO:0000278 195 0.030
Human
negative regulation of phosphorylation GO:0042326 166 0.029
ribonucleotide metabolic process GO:0009259 291 0.029
negative regulation of mapk cascade GO:0043409 65 0.029
g1 s transition of mitotic cell cycle GO:0000082 57 0.029
negative regulation of cell proliferation GO:0008285 296 0.029
circadian rhythm GO:0007623 114 0.029
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.028
stress activated protein kinase signaling cascade GO:0031098 81 0.028
cellular response to dna damage stimulus GO:0006974 207 0.028
sensory perception GO:0007600 245 0.028
protein modification by small protein conjugation or removal GO:0070647 207 0.028
Human
protein methylation GO:0006479 81 0.028
organic cyclic compound catabolic process GO:1901361 295 0.028
organonitrogen compound catabolic process GO:1901565 264 0.027
striated muscle contraction GO:0006941 45 0.027
nucleoside metabolic process GO:0009116 246 0.027
purine nucleoside triphosphate catabolic process GO:0009146 203 0.027
purine ribonucleotide metabolic process GO:0009150 290 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.027
regulation of protein kinase activity GO:0045859 232 0.026
muscle adaptation GO:0043500 39 0.026
mitotic g1 dna damage checkpoint GO:0031571 4 0.026
protein alkylation GO:0008213 81 0.025
regulation of cell cycle GO:0051726 281 0.025
Human
methylation GO:0032259 134 0.025
amine metabolic process GO:0009308 45 0.025
cell division GO:0051301 120 0.025
Human
regulation of map kinase activity GO:0043405 120 0.025
response to organonitrogen compound GO:0010243 246 0.025
nucleoside phosphate catabolic process GO:1901292 222 0.024
homeostasis of number of cells GO:0048872 210 0.024
ras protein signal transduction GO:0007265 77 0.024
nucleotide metabolic process GO:0009117 332 0.024
regulation of cellular amine metabolic process GO:0033238 20 0.024
skeletal system morphogenesis GO:0048705 203 0.024
nucleoside triphosphate metabolic process GO:0009141 230 0.024
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.024
positive regulation of striated muscle contraction GO:0045989 3 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
cellular response to growth factor stimulus GO:0071363 197 0.024
nucleoside phosphate metabolic process GO:0006753 338 0.023
positive regulation of cardiac muscle contraction GO:0060452 2 0.023
palate development GO:0060021 76 0.023
cardiac muscle contraction GO:0060048 32 0.023
nucleotide catabolic process GO:0009166 217 0.023
cellular macromolecule catabolic process GO:0044265 206 0.023
positive regulation of apoptotic process GO:0043065 217 0.023
regulation of ion transport GO:0043269 215 0.023
regulation of system process GO:0044057 200 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.023
histone methylation GO:0016571 71 0.022
positive regulation of cell death GO:0010942 224 0.022
microtubule based process GO:0007017 236 0.022
Human
response to oxidative stress GO:0006979 123 0.022
circulatory system process GO:0003013 197 0.022
regulation of protein serine threonine kinase activity GO:0071900 157 0.022
response to light stimulus GO:0009416 135 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.022
nucleoside catabolic process GO:0009164 206 0.022
ribonucleotide catabolic process GO:0009261 208 0.022
positive regulation of protein binding GO:0032092 29 0.022
regulation of neuron differentiation GO:0045664 281 0.022
spermatogenesis GO:0007283 284 0.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
positive regulation of endopeptidase activity GO:0010950 43 0.021
regulation of jnk cascade GO:0046328 62 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
cell fate commitment GO:0045165 210 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
aromatic compound catabolic process GO:0019439 286 0.020
leukocyte homeostasis GO:0001776 79 0.020
cell cycle g1 s phase transition GO:0044843 57 0.020
regulation of cell projection organization GO:0031344 206 0.020
positive regulation of cell development GO:0010720 237 0.020
jnk cascade GO:0007254 72 0.020
regulation of protein binding GO:0043393 60 0.020
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.020
glycosyl compound catabolic process GO:1901658 206 0.020
regulation of cellular response to stress GO:0080135 159 0.020
regulation of cell cycle phase transition GO:1901987 77 0.020
organic anion transport GO:0015711 137 0.020
ribonucleoside triphosphate catabolic process GO:0009203 199 0.020
response to uv GO:0009411 44 0.020
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.019
blood circulation GO:0008015 195 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
regulation of binding GO:0051098 111 0.019
anion transport GO:0006820 177 0.019
rho protein signal transduction GO:0007266 32 0.019
histone acetylation GO:0016573 41 0.019
negative regulation of dna replication GO:0008156 4 0.019
peptidyl lysine modification GO:0018205 77 0.019
muscle contraction GO:0006936 101 0.019
negative regulation of organelle organization GO:0010639 90 0.019
positive regulation of stress activated mapk cascade GO:0032874 48 0.019
positive regulation of nervous system development GO:0051962 221 0.019
wnt signaling pathway GO:0016055 188 0.019
smooth muscle contraction GO:0006939 44 0.019
regulation of histone deacetylation GO:0031063 12 0.019
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.018
relaxation of muscle GO:0090075 18 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
purine containing compound catabolic process GO:0072523 213 0.018
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.018
cilium morphogenesis GO:0060271 102 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
cytokine production GO:0001816 319 0.018
negative regulation of muscle contraction GO:0045932 12 0.018
positive regulation of proteolysis GO:0045862 85 0.018
response to acid chemical GO:0001101 111 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
brown fat cell differentiation GO:0050873 36 0.018
response to transforming growth factor beta GO:0071559 88 0.018
metal ion homeostasis GO:0055065 189 0.017
regulation of muscle adaptation GO:0043502 31 0.017
nitrogen compound transport GO:0071705 271 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
compound eye development GO:0048749 1 0.017
regulation of histone methylation GO:0031060 30 0.017
transmission of nerve impulse GO:0019226 76 0.017
response to osmotic stress GO:0006970 21 0.017
regulation of blood vessel size GO:0050880 56 0.017
skeletal system development GO:0001501 356 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
protein catabolic process GO:0030163 221 0.017
actin cytoskeleton organization GO:0030036 220 0.017
cellular homeostasis GO:0019725 240 0.017
heterocycle catabolic process GO:0046700 280 0.017
negative regulation of cell cycle process GO:0010948 69 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
wound healing GO:0042060 157 0.016
stress activated mapk cascade GO:0051403 80 0.016
camera type eye development GO:0043010 266 0.016
response to radiation GO:0009314 165 0.016
negative regulation of cell cycle phase transition GO:1901988 48 0.016
demethylation GO:0070988 23 0.016
negative regulation of growth GO:0045926 99 0.016
histone h3 acetylation GO:0043966 14 0.016
action potential GO:0001508 78 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
myeloid cell differentiation GO:0030099 233 0.016
organ growth GO:0035265 117 0.016
response to lipopolysaccharide GO:0032496 128 0.016
regulation of blood circulation GO:1903522 93 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
multicellular organismal signaling GO:0035637 91 0.016
renal system development GO:0072001 225 0.016
leukocyte differentiation GO:0002521 342 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
Human
regulation of protein deacetylation GO:0090311 17 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
regulation of peptidase activity GO:0052547 96 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
cellular response to lipid GO:0071396 145 0.016
response to hypoxia GO:0001666 58 0.016
macromolecule catabolic process GO:0009057 281 0.016
mitotic cell cycle process GO:1903047 159 0.015
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
carbohydrate metabolic process GO:0005975 230 0.015
positive regulation of cell division GO:0051781 31 0.015
embryonic skeletal system development GO:0048706 120 0.015
membrane organization GO:0061024 245 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
lateral inhibition GO:0046331 1 0.015
response to decreased oxygen levels GO:0036293 59 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
relaxation of smooth muscle GO:0044557 8 0.015
regulation of stress activated mapk cascade GO:0032872 69 0.015
muscle hypertrophy GO:0014896 24 0.015
regulation of heart contraction GO:0008016 77 0.015
synaptic transmission GO:0007268 329 0.015
developmental growth involved in morphogenesis GO:0060560 138 0.015
cellular response to acid chemical GO:0071229 68 0.015
regulation of protein localization GO:0032880 231 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
positive regulation of jnk cascade GO:0046330 46 0.015
regulation of ossification GO:0030278 112 0.015
cellular chemical homeostasis GO:0055082 215 0.015
cell type specific apoptotic process GO:0097285 268 0.015
regulation of cytoskeleton organization GO:0051493 122 0.014
multi multicellular organism process GO:0044706 109 0.014
negative regulation of ossification GO:0030279 49 0.014
regulation of muscle system process GO:0090257 80 0.014
divalent inorganic cation transport GO:0072511 178 0.014
positive regulation of gtpase activity GO:0043547 85 0.014
positive regulation of cellular amine metabolic process GO:0033240 5 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
negative regulation of map kinase activity GO:0043407 34 0.014
neuronal action potential GO:0019228 54 0.014
cell activation involved in immune response GO:0002263 126 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
regulation of metal ion transport GO:0010959 106 0.014
skin development GO:0043588 220 0.014
blood vessel morphogenesis GO:0048514 285 0.014
Mouse
organelle assembly GO:0070925 177 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
regulation of proteolysis GO:0030162 164 0.014
gtp catabolic process GO:0006184 143 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
protein localization to organelle GO:0033365 185 0.013
cation homeostasis GO:0055080 212 0.013
protein deacylation GO:0035601 36 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
dna replication GO:0006260 52 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
regulation of cellular response to growth factor stimulus GO:0090287 82 0.013
regulation of tube size GO:0035150 57 0.013
nuclear division GO:0000280 158 0.013
Human
histone lysine methylation GO:0034968 50 0.013
cellular protein complex assembly GO:0043623 116 0.013
cognition GO:0050890 149 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
epithelial cell development GO:0002064 159 0.013
positive regulation of chromatin modification GO:1903310 28 0.013
locomotor rhythm GO:0045475 8 0.013
divalent metal ion transport GO:0070838 172 0.013
sensory perception of sound GO:0007605 97 0.013
tissue homeostasis GO:0001894 115 0.013
regulation of cell motility GO:2000145 236 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
positive regulation of chromosome organization GO:2001252 33 0.012
nucleotide excision repair GO:0006289 13 0.012
regulation of protein complex assembly GO:0043254 83 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
regulation of kinase activity GO:0043549 249 0.012
cytoplasmic transport GO:0016482 234 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
cellular protein catabolic process GO:0044257 155 0.012
positive regulation of gtp catabolic process GO:0033126 85 0.012
calcium ion transport GO:0006816 159 0.012
regulation of body fluid levels GO:0050878 162 0.012
t cell activation GO:0042110 289 0.012
negative regulation of organ growth GO:0046621 17 0.012
histone deacetylation GO:0016575 26 0.012
positive regulation of peptidase activity GO:0010952 49 0.012
heart contraction GO:0060047 93 0.012
positive regulation of heart contraction GO:0045823 14 0.012
regulation of osteoblast differentiation GO:0045667 67 0.012
heart process GO:0003015 94 0.012
organic hydroxy compound transport GO:0015850 93 0.012
fertilization GO:0009566 127 0.012
cellular ion homeostasis GO:0006873 165 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
negative regulation of cell development GO:0010721 169 0.012
oxidation reduction process GO:0055114 342 0.012
cell cycle arrest GO:0007050 37 0.012
organophosphate catabolic process GO:0046434 232 0.012
sodium ion transport GO:0006814 73 0.012
calcium ion transmembrane transport GO:0070588 85 0.012
sensory perception of mechanical stimulus GO:0050954 107 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
cardiac muscle hypertrophy GO:0003300 23 0.012
epidermis development GO:0008544 187 0.011
regulation of muscle contraction GO:0006937 49 0.011
ossification GO:0001503 216 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
regulation of endopeptidase activity GO:0052548 89 0.011
protein localization to nucleus GO:0034504 121 0.011
gland development GO:0048732 330 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
germ cell development GO:0007281 185 0.011
cell maturation GO:0048469 127 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
oocyte axis specification GO:0007309 2 0.011
regulation of transmembrane transport GO:0034762 128 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
peptide secretion GO:0002790 114 0.011
protein localization to membrane GO:0072657 108 0.011
urogenital system development GO:0001655 261 0.011
gtp metabolic process GO:0046039 144 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
regulation of organ growth GO:0046620 61 0.011
muscle tissue development GO:0060537 308 0.011
glucose homeostasis GO:0042593 128 0.011
leukocyte activation involved in immune response GO:0002366 126 0.011
positive regulation of histone methylation GO:0031062 16 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
positive regulation of histone modification GO:0031058 28 0.011
development of primary sexual characteristics GO:0045137 143 0.011
cell adhesion GO:0007155 329 0.011
regulation of cardiac muscle contraction GO:0055117 21 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 12 0.010
response to gamma radiation GO:0010332 22 0.010
regulation of protein catabolic process GO:0042176 108 0.010
skeletal muscle organ development GO:0060538 163 0.010
connective tissue development GO:0061448 179 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
hexose metabolic process GO:0019318 98 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
regulation of cellular component size GO:0032535 121 0.010
relaxation of vascular smooth muscle GO:0060087 7 0.010
response to oxygen levels GO:0070482 62 0.010
regulation of neuron projection development GO:0010975 169 0.010
positive regulation of growth GO:0045927 104 0.010
actin filament organization GO:0007015 113 0.010
calcium ion homeostasis GO:0055074 127 0.010
regulation of smooth muscle contraction GO:0006940 22 0.010
vascular process in circulatory system GO:0003018 62 0.010
regulation of feeding behavior GO:0060259 3 0.010
response to inorganic substance GO:0010035 96 0.010
regulation of secretion GO:0051046 274 0.010
regulation of cytokine production GO:0001817 266 0.010
organic acid transport GO:0015849 101 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
maintenance of location GO:0051235 89 0.010
peptide transport GO:0015833 133 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010

Cul9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.032
central nervous system disease DOID:331 0 0.013
disease of metabolism DOID:0014667 0 0.013
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.012
disease of cellular proliferation DOID:14566 0 0.011