Mus musculus

0 known processes

Txn2

thioredoxin 2

(Aliases: Trx2,2510006J11Rik,AI788873)

Txn2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of ruffle assembly GO:1900029 1 0.104
generation of precursor metabolites and energy GO:0006091 103 0.103
oxidation reduction process GO:0055114 342 0.086
Rat
mitochondrion organization GO:0007005 134 0.073
rho protein signal transduction GO:0007266 32 0.072
establishment of protein localization to organelle GO:0072594 118 0.060
transmembrane transport GO:0055085 412 0.052
germ cell development GO:0007281 185 0.050
small gtpase mediated signal transduction GO:0007264 97 0.050
protein import GO:0017038 101 0.046
purine ribonucleoside metabolic process GO:0046128 241 0.046
synaptic transmission GO:0007268 329 0.046
male gamete generation GO:0048232 285 0.043
dicarboxylic acid catabolic process GO:0043649 2 0.043
protein localization to organelle GO:0033365 185 0.042
cellular amino acid metabolic process GO:0006520 103 0.040
negative regulation of purine nucleotide catabolic process GO:0033122 9 0.039
protein targeting GO:0006605 143 0.038
response to organic cyclic compound GO:0014070 198 0.038
Rat
multicellular organism growth GO:0035264 161 0.038
cytoplasmic transport GO:0016482 234 0.037
carbohydrate derivative biosynthetic process GO:1901137 183 0.036
epithelial tube morphogenesis GO:0060562 303 0.035
cellular respiration GO:0045333 38 0.034
organonitrogen compound biosynthetic process GO:1901566 192 0.033
mitochondrial membrane organization GO:0007006 26 0.032
cellular lipid metabolic process GO:0044255 323 0.031
ribose phosphate metabolic process GO:0019693 291 0.030
nucleoside phosphate metabolic process GO:0006753 338 0.029
compound eye development GO:0048749 1 0.029
intracellular protein transport GO:0006886 204 0.029
positive regulation of protein modification process GO:0031401 299 0.029
regulation of secretion by cell GO:1903530 249 0.028
ribonucleotide metabolic process GO:0009259 291 0.028
ribonucleoside metabolic process GO:0009119 245 0.028
negative regulation of cell proliferation GO:0008285 296 0.027
morphogenesis of a branching epithelium GO:0061138 193 0.027
negative regulation of ras gtpase activity GO:0034261 3 0.026
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.025
epithelial cell proliferation GO:0050673 174 0.025
regulation of organelle organization GO:0033043 289 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
establishment of protein localization to membrane GO:0090150 54 0.025
regulation of actin filament based process GO:0032970 99 0.025
purine nucleotide metabolic process GO:0006163 302 0.024
nucleoside triphosphate catabolic process GO:0009143 205 0.024
response to organonitrogen compound GO:0010243 246 0.024
apoptotic signaling pathway GO:0097190 306 0.024
regulation of response to wounding GO:1903034 189 0.023
regulation of cell motility GO:2000145 236 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
organonitrogen compound catabolic process GO:1901565 264 0.022
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.022
cation transport GO:0006812 399 0.022
regulation of cellular amine metabolic process GO:0033238 20 0.022
negative regulation of camp mediated signaling GO:0043951 3 0.021
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.021
spermatogenesis GO:0007283 284 0.021
cellular response to hormone stimulus GO:0032870 150 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
purine nucleoside metabolic process GO:0042278 241 0.020
purine containing compound metabolic process GO:0072521 311 0.020
rap protein signal transduction GO:0032486 3 0.020
regulation of map kinase activity GO:0043405 120 0.020
cellular protein complex assembly GO:0043623 116 0.020
protein modification by small protein conjugation GO:0032446 187 0.020
regulation of protein localization GO:0032880 231 0.020
muscle cell development GO:0055001 133 0.020
defecation GO:0030421 1 0.020
mitochondrion morphogenesis GO:0070584 13 0.020
regulation of ras gtpase activity GO:0032318 88 0.019
inflammatory response GO:0006954 244 0.019
dephosphorylation GO:0016311 129 0.019
regulation of cellular response to stress GO:0080135 159 0.019
mitochondrial electron transport ubiquinol to cytochrome c GO:0006122 2 0.019
lung development GO:0030324 164 0.019
cellular response to lipid GO:0071396 145 0.019
nucleoside metabolic process GO:0009116 246 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
protein localization to membrane GO:0072657 108 0.018
membrane organization GO:0061024 245 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.018
regulation of mapk cascade GO:0043408 248 0.018
oocyte axis specification GO:0007309 2 0.018
glucose homeostasis GO:0042593 128 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.018
regulation of cellular amino acid metabolic process GO:0006521 5 0.018
cytokine production GO:0001816 319 0.018
striated muscle tissue development GO:0014706 293 0.017
nucleotide metabolic process GO:0009117 332 0.017
negative regulation of molecular function GO:0044092 258 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
regulation of nucleoside metabolic process GO:0009118 130 0.017
regulation of defense response GO:0031347 233 0.017
response to light stimulus GO:0009416 135 0.017
renal system development GO:0072001 225 0.017
cellular amine metabolic process GO:0044106 44 0.016
cellular ion homeostasis GO:0006873 165 0.016
protein localization to mitochondrion GO:0070585 15 0.016
peptidyl amino acid modification GO:0018193 336 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
muscle cell differentiation GO:0042692 261 0.016
stem cell differentiation GO:0048863 268 0.016
positive regulation of cell migration GO:0030335 109 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
regulation of feeding behavior GO:0060259 3 0.016
translation GO:0006412 93 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
heterocycle catabolic process GO:0046700 280 0.015
organic acid biosynthetic process GO:0016053 86 0.015
peptide transport GO:0015833 133 0.015
ion transmembrane transport GO:0034220 361 0.015
regulation of cell adhesion GO:0030155 154 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
skin development GO:0043588 220 0.015
response to peptide GO:1901652 136 0.015
nitrogen compound transport GO:0071705 271 0.015
positive regulation of cellular amine metabolic process GO:0033240 5 0.014
protein ubiquitination GO:0016567 171 0.014
respiratory tube development GO:0030323 167 0.014
gastrulation GO:0007369 116 0.014
neuron neuron synaptic transmission GO:0007270 69 0.014
leukocyte differentiation GO:0002521 342 0.014
cation transmembrane transport GO:0098655 266 0.014
t cell activation GO:0042110 289 0.014
bmp signaling pathway GO:0030509 93 0.014
amide transport GO:0042886 138 0.014
regulation of cytokine production GO:0001817 266 0.014
regulation of cell activation GO:0050865 289 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.014
regulation of hydrolase activity GO:0051336 246 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
digestive tract development GO:0048565 190 0.013
development of primary sexual characteristics GO:0045137 143 0.013
leukocyte mediated immunity GO:0002443 174 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
ras protein signal transduction GO:0007265 77 0.013
branching morphogenesis of an epithelial tube GO:0048754 159 0.013
female gamete generation GO:0007292 74 0.013
wound healing GO:0042060 157 0.013
t cell differentiation GO:0030217 174 0.013
single organism cell adhesion GO:0098602 156 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
single organism nuclear import GO:1902593 95 0.013
cellular homeostasis GO:0019725 240 0.012
regulation of leukocyte proliferation GO:0070663 121 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
response to radiation GO:0009314 165 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
sensory organ morphogenesis GO:0090596 242 0.012
gland development GO:0048732 330 0.012
response to inorganic substance GO:0010035 96 0.012
regulation of cellular ketone metabolic process GO:0010565 66 0.012
immune effector process GO:0002252 321 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
lipid localization GO:0010876 126 0.012
regulation of hormone levels GO:0010817 211 0.012
response to temperature stimulus GO:0009266 55 0.012
aromatic compound catabolic process GO:0019439 286 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
fatty acid metabolic process GO:0006631 121 0.012
mapk cascade GO:0000165 281 0.012
positive regulation of rap gtpase activity GO:0032854 3 0.012
positive regulation of cell motility GO:2000147 116 0.012
histone h4 k16 acetylation GO:0043984 3 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
regulation of t cell activation GO:0050863 170 0.011
amine metabolic process GO:0009308 45 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
positive regulation of epithelial cell proliferation GO:0050679 68 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
lymphocyte differentiation GO:0030098 242 0.011
learning or memory GO:0007611 148 0.011
carbohydrate metabolic process GO:0005975 230 0.011
multi multicellular organism process GO:0044706 109 0.011
developmental maturation GO:0021700 193 0.011
response to endoplasmic reticulum stress GO:0034976 53 0.011
regulation of reproductive process GO:2000241 66 0.011
c4 dicarboxylate transport GO:0015740 3 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
organic cyclic compound catabolic process GO:1901361 295 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
striated muscle cell development GO:0055002 125 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
sensory perception GO:0007600 245 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
cell growth GO:0016049 130 0.011
peptide metabolic process GO:0006518 46 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
exocytosis GO:0006887 121 0.011
organophosphate catabolic process GO:0046434 232 0.011
second messenger mediated signaling GO:0019932 73 0.011
nucleobase containing small molecule metabolic process GO:0055086 352 0.011
negative regulation of nucleoside metabolic process GO:0045978 11 0.011
regulation of translation GO:0006417 71 0.011
cellular macromolecule catabolic process GO:0044265 206 0.011
positive regulation of hydrolase activity GO:0051345 148 0.010
urogenital system development GO:0001655 261 0.010
regulation of secretion GO:0051046 274 0.010
regulation of membrane potential GO:0042391 192 0.010
positive regulation of map kinase activity GO:0043406 84 0.010
purine containing compound biosynthetic process GO:0072522 70 0.010
cellular response to peptide hormone stimulus GO:0071375 92 0.010
oogenesis GO:0048477 56 0.010
cellular response to organonitrogen compound GO:0071417 145 0.010
cyclic purine nucleotide metabolic process GO:0052652 43 0.010
purine nucleoside catabolic process GO:0006152 205 0.010
placenta development GO:0001890 140 0.010

Txn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.019
endocrine gland cancer DOID:170 0 0.015
disease of anatomical entity DOID:7 0 0.015
central nervous system disease DOID:331 0 0.015
nervous system disease DOID:863 0 0.015