Mus musculus

115 known processes

Txn1

thioredoxin 1

(Aliases: ADF,Txn,Trx1,AW550880)

Txn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.219
cellular response to dna damage stimulus GO:0006974 207 0.083
response to oxidative stress GO:0006979 123 0.081
Human
cellular nitrogen compound catabolic process GO:0044270 280 0.071
cation transport GO:0006812 399 0.069
cellular response to lipid GO:0071396 145 0.069
negative regulation of lipopolysaccharide mediated signaling pathway GO:0031665 3 0.068
heterocycle catabolic process GO:0046700 280 0.067
amine metabolic process GO:0009308 45 0.065
cellular amine metabolic process GO:0044106 44 0.065
cellular ketone metabolic process GO:0042180 84 0.064
monocarboxylic acid metabolic process GO:0032787 191 0.061
hemostasis GO:0007599 78 0.058
cellular macromolecule catabolic process GO:0044265 206 0.056
myeloid cell differentiation GO:0030099 233 0.056
response to lipopolysaccharide GO:0032496 128 0.056
inflammatory response GO:0006954 244 0.053
t cell activation GO:0042110 289 0.053
cellular response to molecule of bacterial origin GO:0071219 83 0.051
dna metabolic process GO:0006259 303 0.051
regulation of cellular ketone metabolic process GO:0010565 66 0.050
response to molecule of bacterial origin GO:0002237 143 0.049
cellular response to lipopolysaccharide GO:0071222 77 0.048
nucleobase containing small molecule metabolic process GO:0055086 352 0.048
regulation of cellular amino acid metabolic process GO:0006521 5 0.045
apoptotic signaling pathway GO:0097190 306 0.044
ion transmembrane transport GO:0034220 361 0.044
innate immune response GO:0045087 157 0.044
cellular lipid metabolic process GO:0044255 323 0.043
reactive oxygen species metabolic process GO:0072593 84 0.043
coagulation GO:0050817 78 0.042
spermatogenesis GO:0007283 284 0.041
nucleotide metabolic process GO:0009117 332 0.041
cellular response to biotic stimulus GO:0071216 92 0.041
immune effector process GO:0002252 321 0.041
leukocyte mediated immunity GO:0002443 174 0.040
aromatic compound catabolic process GO:0019439 286 0.040
mapk cascade GO:0000165 281 0.040
leukocyte differentiation GO:0002521 342 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
carbohydrate metabolic process GO:0005975 230 0.038
oxidation reduction process GO:0055114 342 0.038
cellular modified amino acid metabolic process GO:0006575 63 0.038
response to inorganic substance GO:0010035 96 0.038
Human Rat
myeloid cell homeostasis GO:0002262 114 0.038
cytoplasmic transport GO:0016482 234 0.038
regulation of intracellular transport GO:0032386 159 0.037
response to organonitrogen compound GO:0010243 246 0.037
Rat
cell killing GO:0001906 67 0.036
negative regulation of molecular function GO:0044092 258 0.036
purine containing compound metabolic process GO:0072521 311 0.036
ribonucleotide metabolic process GO:0009259 291 0.036
actin cytoskeleton organization GO:0030036 220 0.035
regulation of cellular amine metabolic process GO:0033238 20 0.035
protein maturation GO:0051604 176 0.035
sensory perception GO:0007600 245 0.033
positive regulation of protein modification process GO:0031401 299 0.033
Human
leukocyte mediated cytotoxicity GO:0001909 62 0.033
positive regulation of secretion GO:0051047 130 0.033
regulation of cell activation GO:0050865 289 0.033
nitrogen compound transport GO:0071705 271 0.033
t cell differentiation GO:0030217 174 0.033
membrane organization GO:0061024 245 0.032
regulation of t cell activation GO:0050863 170 0.032
positive regulation of secretion by cell GO:1903532 114 0.032
positive regulation of protein phosphorylation GO:0001934 242 0.032
Human
response to oxygen radical GO:0000305 16 0.032
regulation of lymphocyte activation GO:0051249 240 0.031
positive regulation of mapk cascade GO:0043410 170 0.031
nucleoside phosphate metabolic process GO:0006753 338 0.031
ribose phosphate metabolic process GO:0019693 291 0.031
lymphocyte proliferation GO:0046651 164 0.031
macromolecule catabolic process GO:0009057 281 0.030
cellular chemical homeostasis GO:0055082 215 0.030
Rat
cellular homeostasis GO:0019725 240 0.030
lymphocyte mediated immunity GO:0002449 139 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
negative regulation of t cell activation GO:0050868 65 0.030
intracellular protein transport GO:0006886 204 0.030
regulation of reactive oxygen species metabolic process GO:2000377 40 0.030
transmembrane transport GO:0055085 412 0.029
response to extracellular stimulus GO:0009991 127 0.029
blood coagulation GO:0007596 76 0.029
negative regulation of lymphocyte activation GO:0051250 91 0.029
ubiquitin dependent protein catabolic process GO:0006511 129 0.029
negative regulation of immune system process GO:0002683 209 0.029
response to acid chemical GO:0001101 111 0.028
Rat
protein import GO:0017038 101 0.028
Human
negative regulation of cell proliferation GO:0008285 296 0.028
male gamete generation GO:0048232 285 0.028
regulation of mapk cascade GO:0043408 248 0.028
peptidyl amino acid modification GO:0018193 336 0.028
Human
regulation of lymphocyte differentiation GO:0045619 107 0.028
multicellular organismal homeostasis GO:0048871 164 0.028
response to organic cyclic compound GO:0014070 198 0.027
Rat
regulation of response to wounding GO:1903034 189 0.027
negative regulation of leukocyte differentiation GO:1902106 51 0.027
t cell proliferation GO:0042098 120 0.027
leukocyte proliferation GO:0070661 172 0.026
protein localization to nucleus GO:0034504 121 0.026
Human
organonitrogen compound biosynthetic process GO:1901566 192 0.026
regulation of protein localization GO:0032880 231 0.026
regulation of protein kinase activity GO:0045859 232 0.026
regulation of transferase activity GO:0051338 263 0.026
positive regulation of protein kinase activity GO:0045860 144 0.026
cellular response to external stimulus GO:0071496 88 0.025
regulation of establishment of protein localization GO:0070201 181 0.025
meiotic cell cycle process GO:1903046 77 0.025
lymphocyte differentiation GO:0030098 242 0.025
positive regulation of hemostasis GO:1900048 10 0.025
organic hydroxy compound metabolic process GO:1901615 203 0.025
regulation of leukocyte differentiation GO:1902105 159 0.025
regulation of anatomical structure size GO:0090066 178 0.025
nuclear transport GO:0051169 139 0.025
regulation of secretion GO:0051046 274 0.025
modification dependent macromolecule catabolic process GO:0043632 133 0.024
stress activated mapk cascade GO:0051403 80 0.024
anion transport GO:0006820 177 0.024
lipid biosynthetic process GO:0008610 179 0.024
positive regulation of organelle organization GO:0010638 128 0.024
positive regulation of viral genome replication GO:0045070 2 0.024
peptide transport GO:0015833 133 0.024
regulation of ion transport GO:0043269 215 0.024
monosaccharide metabolic process GO:0005996 106 0.024
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.024
organelle fission GO:0048285 170 0.024
negative regulation of cellular amine metabolic process GO:0033239 1 0.024
cellular ion homeostasis GO:0006873 165 0.024
regulation of apoptotic signaling pathway GO:2001233 197 0.023
regulation of secretion by cell GO:1903530 249 0.023
regulation of multi organism process GO:0043900 111 0.023
negative regulation of cell activation GO:0050866 111 0.023
inorganic cation transmembrane transport GO:0098662 207 0.023
nuclear division GO:0000280 158 0.023
development of primary male sexual characteristics GO:0046546 88 0.023
regulation of hemostasis GO:1900046 28 0.022
regulation of protein serine threonine kinase activity GO:0071900 157 0.022
regulation of protein import into nucleus GO:0042306 52 0.022
Human
purine containing compound catabolic process GO:0072523 213 0.022
placenta development GO:0001890 140 0.022
regulation of kinase activity GO:0043549 249 0.022
response to superoxide GO:0000303 16 0.022
regulation of membrane potential GO:0042391 192 0.022
establishment of protein localization to organelle GO:0072594 118 0.022
Human
inorganic ion transmembrane transport GO:0098660 234 0.022
carbohydrate derivative biosynthetic process GO:1901137 183 0.022
protein targeting GO:0006605 143 0.022
Human
g protein coupled receptor signaling pathway GO:0007186 243 0.021
organonitrogen compound catabolic process GO:1901565 264 0.021
organelle localization GO:0051640 179 0.021
regulation of reproductive process GO:2000241 66 0.021
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.021
alcohol metabolic process GO:0006066 116 0.021
negative regulation of multi organism process GO:0043901 68 0.021
multicellular organism growth GO:0035264 161 0.021
hydrogen peroxide catabolic process GO:0042744 5 0.021
tissue homeostasis GO:0001894 115 0.021
cell aging GO:0007569 35 0.020
response to reactive oxygen species GO:0000302 56 0.020
Human
synaptic transmission GO:0007268 329 0.020
amide transport GO:0042886 138 0.020
epidermis development GO:0008544 187 0.020
negative regulation of protein metabolic process GO:0051248 282 0.020
circulatory system process GO:0003013 197 0.020
purine nucleotide metabolic process GO:0006163 302 0.020
cation homeostasis GO:0055080 212 0.020
regulation of organelle organization GO:0033043 289 0.020
engulfment of apoptotic cell GO:0043652 3 0.020
positive regulation of kinase activity GO:0033674 155 0.020
modification dependent protein catabolic process GO:0019941 133 0.020
mitotic cell cycle GO:0000278 195 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
cellular response to extracellular stimulus GO:0031668 81 0.019
mrna metabolic process GO:0016071 84 0.019
blood circulation GO:0008015 195 0.019
regulation of stress activated mapk cascade GO:0032872 69 0.019
dna integrity checkpoint GO:0031570 28 0.019
actin polymerization or depolymerization GO:0008154 54 0.019
endocytosis GO:0006897 168 0.019
positive regulation of cell death GO:0010942 224 0.019
cell type specific apoptotic process GO:0097285 268 0.019
small molecule biosynthetic process GO:0044283 132 0.018
regulation of system process GO:0044057 200 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
rna processing GO:0006396 105 0.018
retina homeostasis GO:0001895 23 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.018
protein secretion GO:0009306 111 0.018
asymmetric stem cell division GO:0098722 3 0.018
nuclear import GO:0051170 95 0.018
Human
forebrain development GO:0030900 302 0.018
positive regulation of map kinase activity GO:0043406 84 0.018
hexose metabolic process GO:0019318 98 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.018
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.018
regulation of map kinase activity GO:0043405 120 0.018
glucose metabolic process GO:0006006 92 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
homeostasis of number of cells GO:0048872 210 0.018
superoxide metabolic process GO:0006801 27 0.018
cellular response to oxidative stress GO:0034599 76 0.018
Human
regulation of nucleocytoplasmic transport GO:0046822 73 0.018
ribonucleoside metabolic process GO:0009119 245 0.017
ras protein signal transduction GO:0007265 77 0.017
regulation of hormone levels GO:0010817 211 0.017
gland development GO:0048732 330 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
stress activated protein kinase signaling cascade GO:0031098 81 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
muscle cell differentiation GO:0042692 261 0.017
protein catabolic process GO:0030163 221 0.017
positive regulation of transferase activity GO:0051347 167 0.017
neural tube development GO:0021915 160 0.017
regulation of defense response GO:0031347 233 0.017
wound healing GO:0042060 157 0.017
chromatin organization GO:0006325 206 0.017
regulation of coagulation GO:0050818 31 0.017
response to nutrient levels GO:0031667 109 0.017
regulation of cellular component size GO:0032535 121 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
cofactor metabolic process GO:0051186 80 0.017
endomembrane system organization GO:0010256 147 0.017
striated muscle tissue development GO:0014706 293 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
nucleoside catabolic process GO:0009164 206 0.016
single organism nuclear import GO:1902593 95 0.016
Human
extracellular matrix organization GO:0030198 147 0.016
apoptotic mitochondrial changes GO:0008637 48 0.016
lateral inhibition GO:0046331 1 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.016
regulation of cytokine production GO:0001817 266 0.016
natural killer cell mediated immunity GO:0002228 29 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
regulation of t cell differentiation GO:0045580 83 0.016
regulation of peptide transport GO:0090087 91 0.016
glycerolipid metabolic process GO:0046486 122 0.016
regulation of protein targeting GO:1903533 61 0.016
Human
ribonucleotide catabolic process GO:0009261 208 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
positive regulation of response to wounding GO:1903036 66 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.016
cell adhesion GO:0007155 329 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
small gtpase mediated signal transduction GO:0007264 97 0.015
gonad development GO:0008406 141 0.015
developmental maturation GO:0021700 193 0.015
sequestering of metal ion GO:0051238 19 0.015
rna splicing GO:0008380 54 0.015
organophosphate catabolic process GO:0046434 232 0.015
oocyte construction GO:0007308 2 0.015
ear development GO:0043583 200 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
organelle assembly GO:0070925 177 0.015
signal transduction in absence of ligand GO:0038034 55 0.015
locomotory behavior GO:0007626 195 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
rhythmic process GO:0048511 174 0.015
stem cell differentiation GO:0048863 268 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
regulation of cytoskeleton organization GO:0051493 122 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
activation of mapk activity GO:0000187 59 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
plasma membrane organization GO:0007009 90 0.014
protein localization to organelle GO:0033365 185 0.014
Human
regulation of cytoplasmic transport GO:1903649 112 0.014
calcium ion homeostasis GO:0055074 127 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.014
microtubule based process GO:0007017 236 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
cellular response to acid chemical GO:0071229 68 0.014
positive regulation of protein transport GO:0051222 93 0.014
muscle system process GO:0003012 141 0.014
nucleotide catabolic process GO:0009166 217 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
carbohydrate biosynthetic process GO:0016051 74 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
oocyte anterior posterior axis specification GO:0007314 2 0.014
regulation of proteolysis GO:0030162 164 0.014
interspecies interaction between organisms GO:0044419 83 0.014
nucleoside metabolic process GO:0009116 246 0.014
positive regulation of growth GO:0045927 104 0.014
metal ion homeostasis GO:0055065 189 0.014
protein import into nucleus GO:0006606 95 0.014
Human
organic cyclic compound catabolic process GO:1901361 295 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
meiotic cell cycle GO:0051321 122 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
sulfur compound metabolic process GO:0006790 100 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
pole plasm assembly GO:0007315 2 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
divalent metal ion transport GO:0070838 172 0.013
regulation of protein secretion GO:0050708 82 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
male sex differentiation GO:0046661 109 0.013
multi multicellular organism process GO:0044706 109 0.013
compound eye development GO:0048749 1 0.013
fertilization GO:0009566 127 0.013
cytokine production GO:0001816 319 0.013
positive regulation of viral process GO:0048524 5 0.013
negative regulation of reactive oxygen species metabolic process GO:2000378 10 0.013
phospholipid metabolic process GO:0006644 87 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
embryonic epithelial tube formation GO:0001838 130 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.013
regulation of cellular response to stress GO:0080135 159 0.013
Human
organic anion transport GO:0015711 137 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
positive regulation of coagulation GO:0050820 13 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
b cell activation GO:0042113 161 0.013
l ascorbic acid metabolic process GO:0019852 4 0.013
male gonad development GO:0008584 88 0.013
cellular protein complex assembly GO:0043623 116 0.013
cellular response to superoxide GO:0071451 14 0.013
regulation of homeostatic process GO:0032844 182 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
maintenance of location GO:0051235 89 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
cellular response to oxygen radical GO:0071450 14 0.012
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
positive regulation of protein secretion GO:0050714 52 0.012
organic acid biosynthetic process GO:0016053 86 0.012
regulation of inflammatory response GO:0050727 147 0.012
heart contraction GO:0060047 93 0.012
germ cell proliferation GO:0036093 7 0.012
regulation of blood pressure GO:0008217 93 0.012
neural tube formation GO:0001841 108 0.012
regulation of protein transport GO:0051223 163 0.012
skin development GO:0043588 220 0.012
regulation of blood circulation GO:1903522 93 0.012
muscle contraction GO:0006936 101 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.012
alpha amino acid metabolic process GO:1901605 59 0.012
positive regulation of cell activation GO:0050867 158 0.012
regulation of hydrolase activity GO:0051336 246 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
muscle tissue development GO:0060537 308 0.012
rho protein signal transduction GO:0007266 32 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
protein localization to membrane GO:0072657 108 0.012
adult behavior GO:0030534 135 0.012
peptidyl tyrosine modification GO:0018212 145 0.011
purine containing compound biosynthetic process GO:0072522 70 0.011
tube formation GO:0035148 140 0.011
response to hydrogen peroxide GO:0042542 32 0.011
Human
leukocyte migration GO:0050900 124 0.011
divalent inorganic cation transport GO:0072511 178 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
actin filament organization GO:0007015 113 0.011
coenzyme metabolic process GO:0006732 52 0.011
actin filament polymerization GO:0030041 44 0.011
i kappab kinase nf kappab signaling GO:0007249 85 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
sequestering of calcium ion GO:0051208 18 0.011
carbohydrate homeostasis GO:0033500 128 0.011
Rat
chromatin modification GO:0016568 187 0.011
regulation of body fluid levels GO:0050878 162 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
action potential GO:0001508 78 0.011
neuronal action potential GO:0019228 54 0.011
mitochondrion organization GO:0007005 134 0.011
regulation of binding GO:0051098 111 0.011
Human
natural killer cell mediated cytotoxicity GO:0042267 29 0.011
positive regulation of cell development GO:0010720 237 0.011
camera type eye development GO:0043010 266 0.011
cytokinetic process GO:0032506 2 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
regulation of actin cytoskeleton organization GO:0032956 84 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.011
spermatid differentiation GO:0048515 115 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
skeletal system development GO:0001501 356 0.011
response to temperature stimulus GO:0009266 55 0.011
spermatid development GO:0007286 108 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
cellular biogenic amine metabolic process GO:0006576 28 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
regulation of metal ion transport GO:0010959 106 0.011
protein processing GO:0016485 163 0.011
anatomical structure homeostasis GO:0060249 145 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
heart process GO:0003015 94 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.010
cellular protein catabolic process GO:0044257 155 0.010
regulation of blood coagulation GO:0030193 28 0.010
peptidyl serine modification GO:0018209 83 0.010
Human
response to amino acid GO:0043200 37 0.010
Rat
viral process GO:0016032 41 0.010
heart morphogenesis GO:0003007 178 0.010
negative regulation of lymphocyte differentiation GO:0045620 32 0.010
guanosine containing compound metabolic process GO:1901068 144 0.010
mrna processing GO:0006397 63 0.010
methylation GO:0032259 134 0.010
regulation of male germ cell proliferation GO:2000254 3 0.010
mitotic cytokinesis GO:0000281 4 0.010
covalent chromatin modification GO:0016569 163 0.010
multicellular organismal signaling GO:0035637 91 0.010
neuron death GO:0070997 154 0.010
morphogenesis of a branching epithelium GO:0061138 193 0.010
germ cell development GO:0007281 185 0.010
regulation of heart contraction GO:0008016 77 0.010
viral life cycle GO:0019058 36 0.010
ossification GO:0001503 216 0.010
adult locomotory behavior GO:0008344 91 0.010

Txn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021