Mus musculus

187 known processes

Fyn

Fyn proto-oncogene

(Aliases: MGC115870,AI448320,AW552119)

Fyn biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of gamma delta t cell differentiation GO:0045588 6 1.000
Mouse
regulation of mast cell activation GO:0033003 21 1.000
Mouse
positive regulation of t cell mediated cytotoxicity GO:0001916 15 1.000
b cell receptor signaling pathway GO:0050853 20 1.000
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.999
t cell differentiation GO:0030217 174 0.999
Mouse
regulation of b cell receptor signaling pathway GO:0050855 9 0.999
Mouse
regulation of b cell differentiation GO:0045577 23 0.999
cellular amine metabolic process GO:0044106 44 0.999
positive regulation of gamma delta t cell activation GO:0046645 6 0.998
Mouse
antigen receptor mediated signaling pathway GO:0050851 64 0.998
Human Mouse
gamma delta t cell activation GO:0046629 13 0.997
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.997
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 17 0.996
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.996
Human Mouse
regulation of insulin receptor signaling pathway GO:0046626 21 0.996
regulation of cellular ketone metabolic process GO:0010565 66 0.995
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.993
t cell differentiation in thymus GO:0033077 77 0.993
amine metabolic process GO:0009308 45 0.993
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.992
regulation of cellular amine metabolic process GO:0033238 20 0.991
regulation of protein autophosphorylation GO:0031952 8 0.990
immune response regulating signaling pathway GO:0002764 125 0.990
Human Mouse
leukocyte activation involved in immune response GO:0002366 126 0.986
Mouse
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.986
Human Mouse
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.986
negative thymic t cell selection GO:0045060 12 0.985
negative regulation of phosphorylation GO:0042326 166 0.985
Mouse
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.985
Mouse
actin cytoskeleton organization GO:0030036 220 0.984
Fly
response to organonitrogen compound GO:0010243 246 0.984
Rat
positive regulation of antigen receptor mediated signaling pathway GO:0050857 9 0.981
Mouse
b cell differentiation GO:0030183 78 0.981
gamma delta t cell differentiation GO:0042492 11 0.980
Mouse
somatic diversification of immune receptors GO:0002200 53 0.980
negative regulation of t cell mediated cytotoxicity GO:0001915 3 0.980
release of sequestered calcium ion into cytosol GO:0051209 42 0.979
Mouse
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.979
regulation of b cell proliferation GO:0030888 39 0.977
Mouse
cellular response to insulin stimulus GO:0032869 78 0.977
peptidyl tyrosine phosphorylation GO:0018108 143 0.975
t cell activation GO:0042110 289 0.975
positive regulation of isotype switching to igg isotypes GO:0048304 7 0.975
negative regulation of protein phosphorylation GO:0001933 126 0.969
Mouse
calcium ion homeostasis GO:0055074 127 0.969
Mouse
immune response activating signal transduction GO:0002757 116 0.967
Human Mouse
negative regulation of kinase activity GO:0033673 81 0.966
Mouse
sequestering of metal ion GO:0051238 19 0.965
Mouse
positive regulation of alpha beta t cell activation GO:0046635 39 0.965
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.961
peptidyl tyrosine modification GO:0018212 145 0.960
cellular amino acid metabolic process GO:0006520 103 0.959
positive regulation of cell killing GO:0031343 33 0.959
regulation of gamma delta t cell activation GO:0046643 9 0.958
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.958
Mouse
cation transport GO:0006812 399 0.957
Mouse
response to peptide hormone GO:0043434 127 0.955
Rat
insulin receptor signaling pathway GO:0008286 49 0.955
leukocyte differentiation GO:0002521 342 0.951
Mouse
regulation of t cell mediated cytotoxicity GO:0001914 18 0.951
positive regulation of lymphocyte activation GO:0051251 140 0.946
Mouse
protein autophosphorylation GO:0046777 61 0.944
activation of immune response GO:0002253 138 0.941
Human Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.940
b cell proliferation GO:0042100 53 0.939
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.936
Mouse
regulation of t cell differentiation GO:0045580 83 0.935
Mouse
regulation of lymphocyte mediated immunity GO:0002706 84 0.933
calcium ion transport into cytosol GO:0060402 48 0.932
Mouse
immune response inhibiting cell surface receptor signaling pathway GO:0002767 3 0.931
Mouse
positive t cell selection GO:0043368 23 0.929
b cell activation GO:0042113 161 0.928
Mouse
dna metabolic process GO:0006259 303 0.927
negative regulation of immune system process GO:0002683 209 0.924
Mouse
negative t cell selection GO:0043383 13 0.924
regulation of ion homeostasis GO:2000021 64 0.922
Mouse
cytosolic calcium ion homeostasis GO:0051480 70 0.919
Mouse
negative regulation of homeostatic process GO:0032845 71 0.912
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.912
Rat
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.911
positive regulation of t cell differentiation GO:0045582 52 0.906
Mouse
positive regulation of b cell receptor signaling pathway GO:0050861 4 0.905
Mouse
positive regulation of map kinase activity GO:0043406 84 0.904
calcium ion transport GO:0006816 159 0.900
Mouse
positive thymic t cell selection GO:0045059 13 0.898
olfactory learning GO:0008355 2 0.895
Fly
positive regulation of apoptotic signaling pathway GO:2001235 95 0.895
regulation of lymphocyte proliferation GO:0050670 117 0.893
Mouse
lateral inhibition GO:0046331 1 0.893
regulation of lymphocyte activation GO:0051249 240 0.891
Mouse
t cell mediated cytotoxicity GO:0001913 26 0.891
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.891
Mouse
single organismal cell cell adhesion GO:0016337 131 0.891
Mouse Fly
regulation of map kinase activity GO:0043405 120 0.890
Mouse
regulation of mapk cascade GO:0043408 248 0.885
Mouse
t cell receptor signaling pathway GO:0050852 46 0.883
Human Mouse
somatic cell dna recombination GO:0016444 51 0.875
cytokine mediated signaling pathway GO:0019221 115 0.874
mapk cascade GO:0000165 281 0.874
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.869
Mouse
cellular response to peptide hormone stimulus GO:0071375 92 0.868
Rat
axonogenesis GO:0007409 274 0.865
Fly
negative regulation of protein metabolic process GO:0051248 282 0.862
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.860
regulation of alpha beta t cell activation GO:0046634 53 0.860
cellular ketone metabolic process GO:0042180 84 0.860
b cell activation involved in immune response GO:0002312 50 0.857
actin polymerization or depolymerization GO:0008154 54 0.856
Fly
dna recombination GO:0006310 92 0.856
positive regulation of t cell mediated immunity GO:0002711 24 0.855
cellular chemical homeostasis GO:0055082 215 0.854
Mouse
negative regulation of protein modification process GO:0031400 163 0.850
Mouse
positive regulation of mapk cascade GO:0043410 170 0.850
Mouse
lymphocyte differentiation GO:0030098 242 0.849
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.848
Mouse Fly
positive regulation of t cell activation GO:0050870 101 0.846
Mouse
negative regulation of transferase activity GO:0051348 85 0.845
Mouse
regulation of alpha beta t cell proliferation GO:0046640 18 0.844
thymic t cell selection GO:0045061 22 0.842
axon guidance GO:0007411 141 0.842
Fly
negative regulation of phosphate metabolic process GO:0045936 184 0.840
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.839
Mouse
alpha beta t cell activation GO:0046631 91 0.838
Mouse
cellular response to peptide GO:1901653 92 0.831
Rat
positive regulation of b cell activation GO:0050871 49 0.830
isotype switching to igg isotypes GO:0048291 10 0.828
positive regulation of intracellular transport GO:0032388 70 0.827
Mouse
regulation of organelle organization GO:0033043 289 0.826
Mouse Fly
regulation of protein serine threonine kinase activity GO:0071900 157 0.825
Mouse
regulation of cell activation GO:0050865 289 0.823
Mouse
negative regulation of protein autophosphorylation GO:0031953 2 0.820
regulation of kinase activity GO:0043549 249 0.818
Zebrafish Mouse Fly
divalent inorganic cation transport GO:0072511 178 0.816
Mouse
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.813
response to insulin GO:0032868 100 0.811
cellular lipid metabolic process GO:0044255 323 0.809
Mouse
regulation of protein kinase activity GO:0045859 232 0.805
Zebrafish Mouse Fly
negative regulation of response to cytokine stimulus GO:0060761 9 0.804
peptidyl tyrosine autophosphorylation GO:0038083 5 0.804
Worm
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.800
Mouse Fly
positive regulation of phospholipase activity GO:0010518 3 0.799
Mouse
positive regulation of transferase activity GO:0051347 167 0.794
Mouse Fly
sequestering of calcium ion GO:0051208 18 0.794
Mouse
adaptive immune response GO:0002250 155 0.793
Mouse
motor neuron axon guidance GO:0008045 26 0.789
regulation of cell cycle GO:0051726 281 0.787
cell activation involved in immune response GO:0002263 126 0.782
Mouse
cd4 positive cd25 positive alpha beta regulatory t cell differentiation GO:0002361 4 0.782
cytoplasmic transport GO:0016482 234 0.780
Mouse
cation homeostasis GO:0055080 212 0.778
Mouse
positive regulation of b cell proliferation GO:0030890 24 0.776
regulation of dendritic cell apoptotic process GO:2000668 3 0.774
Mouse
regulation of cell projection organization GO:0031344 206 0.771
regulation of actin filament length GO:0030832 45 0.769
Fly
positive regulation of leukocyte differentiation GO:1902107 86 0.767
Mouse
lymphocyte activation involved in immune response GO:0002285 93 0.766
regulation of intracellular transport GO:0032386 159 0.764
Mouse
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.763
cell adhesion GO:0007155 329 0.761
Mouse Fly
regulation of cell killing GO:0031341 40 0.758
positive regulation of cellular amine metabolic process GO:0033240 5 0.758
cellular metal ion homeostasis GO:0006875 151 0.756
Mouse
metal ion homeostasis GO:0055065 189 0.756
Mouse
negative regulation of b cell activation GO:0050869 27 0.755
Mouse
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 0.754
positive regulation of cell migration GO:0030335 109 0.749
Mouse
myeloid leukocyte activation GO:0002274 83 0.736
Mouse
positive regulation of immunoglobulin production GO:0002639 28 0.734
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.722
regulation of neuron projection development GO:0010975 169 0.713
somatic diversification of immunoglobulins GO:0016445 43 0.711
positive regulation of t cell proliferation GO:0042102 52 0.705
immune effector process GO:0002252 321 0.700
Mouse
convergent extension GO:0060026 14 0.697
Zebrafish
apoptotic signaling pathway GO:0097190 306 0.695
Rat
positive regulation of alpha beta t cell proliferation GO:0046641 12 0.692
negative regulation of t cell mediated immunity GO:0002710 9 0.690
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.688
peptidyl amino acid modification GO:0018193 336 0.688
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.677
single organism cell adhesion GO:0098602 156 0.670
Mouse Fly
positive regulation of lymphocyte proliferation GO:0050671 70 0.669
regulation of homotypic cell cell adhesion GO:0034110 13 0.667
Mouse
positive regulation of regulatory t cell differentiation GO:0045591 4 0.667
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.662
Fly
regulation of dna recombination GO:0000018 34 0.660
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.658
Mouse
negative regulation of lymphocyte mediated immunity GO:0002707 21 0.656
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.650
positive regulation of adaptive immune response GO:0002821 61 0.646
cellular response to hormone stimulus GO:0032870 150 0.641
Rat
regulation of gamma delta t cell differentiation GO:0045586 9 0.635
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.635
Mouse
regulation of t cell activation GO:0050863 170 0.633
Mouse
digestive tract morphogenesis GO:0048546 147 0.631
Zebrafish Worm
negative regulation of adaptive immune response GO:0002820 25 0.630
regulation of cellular component size GO:0032535 121 0.630
Fly
phospholipid metabolic process GO:0006644 87 0.625
Mouse
regulation of b cell activation GO:0050864 81 0.618
Mouse
endodermal cell fate specification GO:0001714 4 0.613
Worm
regulation of transferase activity GO:0051338 263 0.613
Zebrafish Mouse Fly
regulation of t cell anergy GO:0002667 4 0.609
alpha beta t cell differentiation GO:0046632 69 0.604
Mouse
leukocyte proliferation GO:0070661 172 0.598
regulation of anatomical structure size GO:0090066 178 0.597
Fly
positive regulation of podosome assembly GO:0071803 3 0.597
Mouse
chemotaxis GO:0006935 247 0.596
Fly
t cell mediated immunity GO:0002456 50 0.595
dendrite development GO:0016358 115 0.594
immunoglobulin mediated immune response GO:0016064 69 0.587
integrin mediated signaling pathway GO:0007229 27 0.586
Mouse
spermatogenesis GO:0007283 284 0.585
extrinsic apoptotic signaling pathway GO:0097191 126 0.582
Rat
development of primary sexual characteristics GO:0045137 143 0.580
Worm
positive regulation of cytokine production GO:0001819 174 0.579
Mouse
regulation of lipid kinase activity GO:0043550 14 0.579
Mouse
mitotic cell cycle process GO:1903047 159 0.575
Worm
cellular ion homeostasis GO:0006873 165 0.571
Mouse
lymphocyte mediated immunity GO:0002449 139 0.570
establishment of organelle localization GO:0051656 122 0.570
Worm
positive regulation of kinase activity GO:0033674 155 0.558
Mouse Fly
regulation of isotype switching GO:0045191 22 0.557
small molecule biosynthetic process GO:0044283 132 0.557
male gamete generation GO:0048232 285 0.556
regulation of hydrolase activity GO:0051336 246 0.542
Mouse
peptidyl tyrosine dephosphorylation GO:0035335 23 0.537
positive regulation of lymphocyte differentiation GO:0045621 61 0.534
Mouse
negative regulation of map kinase activity GO:0043407 34 0.529
Mouse
regulation of membrane potential GO:0042391 192 0.527
mast cell activation GO:0045576 27 0.524
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.524
fc receptor mediated stimulatory signaling pathway GO:0002431 4 0.519
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.519
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.511
Mouse
inositol lipid mediated signaling GO:0048017 41 0.511
Rat
negative regulation of leukocyte mediated immunity GO:0002704 29 0.505
positive regulation of protein modification process GO:0031401 299 0.502
Mouse Fly
regulation of lipase activity GO:0060191 15 0.499
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.493
Mouse
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.493
Mouse
activation of mapk activity GO:0000187 59 0.492
serotonin secretion involved in inflammatory response GO:0002442 4 0.490
actin filament organization GO:0007015 113 0.487
Fly
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.484
Rat
regulation of cell migration GO:0030334 219 0.480
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.479
regulation of t cell mediated immunity GO:0002709 34 0.479
immune response inhibiting signal transduction GO:0002765 4 0.477
Mouse
regulation of phospholipase c activity GO:1900274 3 0.477
Mouse
positive regulation of b cell mediated immunity GO:0002714 26 0.472
leukocyte mediated immunity GO:0002443 174 0.471
Mouse
positive regulation of cell activation GO:0050867 158 0.471
Mouse
establishment or maintenance of cell polarity GO:0007163 86 0.466
Worm
negative regulation of mapk cascade GO:0043409 65 0.461
Mouse
neuron migration GO:0001764 122 0.455
cell fate commitment GO:0045165 210 0.455
Worm
erythrocyte differentiation GO:0030218 88 0.455
Mouse
regulation of lymphocyte anergy GO:0002911 4 0.453
ras protein signal transduction GO:0007265 77 0.451
response to peptide GO:1901652 136 0.450
Rat
microtubule based process GO:0007017 236 0.448
Worm
regulation of actin filament polymerization GO:0030833 38 0.445
regulation of exocytosis GO:0017157 61 0.445
Mouse
regulation of t cell proliferation GO:0042129 92 0.444
regulation of immunoglobulin mediated immune response GO:0002889 37 0.439
associative learning GO:0008306 61 0.439
Fly
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.439
Mouse
lipid biosynthetic process GO:0008610 179 0.437
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.434
Rat
microtubule cytoskeleton organization GO:0000226 157 0.433
Worm
response to retinoic acid GO:0032526 56 0.433
Mouse
immunoglobulin production GO:0002377 73 0.432
regulation of tyrosine phosphorylation of stat5 protein GO:0042522 8 0.429
Mouse
defense response to virus GO:0051607 68 0.427
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.426
regulation of cytoskeleton organization GO:0051493 122 0.424
Fly
negative regulation of lymphocyte activation GO:0051250 91 0.423
Mouse
response to growth factor GO:0070848 198 0.422
regulation of production of molecular mediator of immune response GO:0002700 65 0.421
regulation of homeostatic process GO:0032844 182 0.420
Mouse
regulation of protein binding GO:0043393 60 0.418
Mouse
platelet degranulation GO:0002576 6 0.405
Mouse
isotype switching GO:0045190 36 0.400
transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 1 0.396
mast cell activation involved in immune response GO:0002279 20 0.394
Mouse
divalent metal ion transport GO:0070838 172 0.393
Mouse
natural killer cell inhibitory signaling pathway GO:0002769 2 0.393
positive regulation of leukocyte proliferation GO:0070665 73 0.389
synapse assembly GO:0007416 56 0.389
Fly
regulation of cellular response to insulin stimulus GO:1900076 30 0.388
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.388
Rat
regulation of isotype switching to igg isotypes GO:0048302 10 0.385
regulation of b cell mediated immunity GO:0002712 37 0.380
glycerolipid biosynthetic process GO:0045017 50 0.376
negative regulation of synapse assembly GO:0051964 3 0.376
Fly
action potential GO:0001508 78 0.375
positive regulation of protein kinase activity GO:0045860 144 0.372
Fly
production of molecular mediator of immune response GO:0002440 103 0.365
negative regulation of ras protein signal transduction GO:0046580 18 0.364
positive regulation of nervous system development GO:0051962 221 0.362
cell killing GO:0001906 67 0.362
leukocyte mediated cytotoxicity GO:0001909 62 0.356
positive regulation of cell projection organization GO:0031346 95 0.352
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.351
positive regulation of cell motility GO:2000147 116 0.346
Mouse
regulation of adaptive immune response GO:0002819 90 0.342
regulation of platelet activation GO:0010543 17 0.342
Mouse
dephosphorylation GO:0016311 129 0.340
digestive system development GO:0055123 200 0.340
Zebrafish Mouse Worm
b cell mediated immunity GO:0019724 71 0.338
regulation of cell projection assembly GO:0060491 38 0.333
Mouse
organic acid biosynthetic process GO:0016053 86 0.333
small gtpase mediated signal transduction GO:0007264 97 0.331
actin cytoskeleton reorganization GO:0031532 21 0.329
regulation of humoral immune response mediated by circulating immunoglobulin GO:0002923 10 0.326
response to acid chemical GO:0001101 111 0.322
Mouse
bone remodeling GO:0046849 53 0.321
Mouse
response to ethanol GO:0045471 18 0.321
positive regulation of immune effector process GO:0002699 107 0.321
Mouse
neuron projection guidance GO:0097485 141 0.316
Fly
regulation of apoptotic signaling pathway GO:2001233 197 0.316
Rat
t cell selection GO:0045058 34 0.312
immature b cell differentiation GO:0002327 10 0.311
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.311
Mouse
cellular response to lipid GO:0071396 145 0.310
Mouse
memory GO:0007613 58 0.306
Fly
germ cell development GO:0007281 185 0.303
Mouse Fly
tissue homeostasis GO:0001894 115 0.301
Mouse
t cell anergy GO:0002870 4 0.299
muscle cell differentiation GO:0042692 261 0.297
regulation of binding GO:0051098 111 0.294
Mouse
cellular protein complex assembly GO:0043623 116 0.292
regulation of body fluid levels GO:0050878 162 0.290
Mouse
lipid phosphorylation GO:0046834 25 0.287
Mouse
regulation of blood coagulation GO:0030193 28 0.286
Mouse
positive regulation of neuron projection development GO:0010976 79 0.284
negative regulation of molecular function GO:0044092 258 0.284
Mouse
t cell proliferation GO:0042098 120 0.283
cell cell signaling involved in cell fate commitment GO:0045168 35 0.281
positive regulation of phospholipase c activity GO:0010863 2 0.279
Mouse
positive regulation of lipid kinase activity GO:0090218 11 0.278
Mouse
positive regulation of exocytosis GO:0045921 20 0.278
Mouse
synapse organization GO:0050808 125 0.277
Fly
cellular response to biotic stimulus GO:0071216 92 0.276
Mouse
fatty acid biosynthetic process GO:0006633 41 0.269
positive regulation of dna recombination GO:0045911 17 0.268
cellular response to growth factor stimulus GO:0071363 197 0.264
positive regulation of cell death GO:0010942 224 0.264
Mouse
regulation of coagulation GO:0050818 31 0.260
Mouse
organelle localization GO:0051640 179 0.259
Mouse Worm
cellularization GO:0007349 1 0.256
Fly
maintenance of location GO:0051235 89 0.256
Mouse
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.254
Rat
regulation of leukocyte mediated immunity GO:0002703 104 0.254
Mouse
humoral immune response GO:0006959 57 0.254
erk1 and erk2 cascade GO:0070371 77 0.253
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.253
Mouse
negative regulation of lymphocyte proliferation GO:0050672 45 0.252
Mouse
regulation of calcium ion transport GO:0051924 69 0.250
Mouse
sprouting angiogenesis GO:0002040 26 0.250
long term memory GO:0007616 15 0.250
Fly
positive regulation of gtp catabolic process GO:0033126 85 0.249
g protein coupled receptor signaling pathway GO:0007186 243 0.249
gastrulation GO:0007369 116 0.248
Zebrafish Worm
regulation of response to cytokine stimulus GO:0060759 23 0.246
positive regulation of isotype switching GO:0045830 15 0.246
fc receptor mediated inhibitory signaling pathway GO:0002774 1 0.245
Mouse
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.244
Mouse
cell type specific apoptotic process GO:0097285 268 0.242
Mouse Rat
gonad development GO:0008406 141 0.235
Worm
neuron recognition GO:0008038 25 0.232
regulation of regulated secretory pathway GO:1903305 20 0.231
Mouse
monocarboxylic acid metabolic process GO:0032787 191 0.230
detection of mechanical stimulus GO:0050982 27 0.228
regulation of cell shape GO:0008360 39 0.225
canonical wnt signaling pathway GO:0060070 130 0.225
Mouse
regulation of endocytosis GO:0030100 69 0.222
Mouse
positive regulation of growth GO:0045927 104 0.222
regulation of actin filament based process GO:0032970 99 0.221
Fly
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.220
formation of primary germ layer GO:0001704 77 0.218
Worm
positive regulation of cell development GO:0010720 237 0.217
peptidyl serine phosphorylation GO:0018105 74 0.217
regulation of organelle assembly GO:1902115 19 0.216
Mouse
epithelial cell migration GO:0010631 63 0.216
positive regulation of humoral immune response mediated by circulating immunoglobulin GO:0002925 6 0.215
phosphatidylinositol mediated signaling GO:0048015 41 0.211
Rat
response to transforming growth factor beta GO:0071559 88 0.211
negative regulation of cell activation GO:0050866 111 0.209
Mouse
neuron projection extension GO:1990138 64 0.208
regulation of ion transport GO:0043269 215 0.208
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.207
Mouse
neutrophil activation GO:0042119 9 0.205
myeloid leukocyte migration GO:0097529 57 0.203
leukocyte cell cell adhesion GO:0007159 14 0.202
regulation of alpha beta t cell differentiation GO:0046637 35 0.200
endothelial cell migration GO:0043542 44 0.200
positive regulation of protein phosphorylation GO:0001934 242 0.199
Mouse Fly
regulation of actin polymerization or depolymerization GO:0008064 45 0.198
Fly
lymphocyte proliferation GO:0046651 164 0.197
transmission of nerve impulse GO:0019226 76 0.196
negative regulation of leukocyte differentiation GO:1902106 51 0.196
Mouse
regulation of nucleotide biosynthetic process GO:0030808 34 0.196
endomembrane system organization GO:0010256 147 0.194
organonitrogen compound catabolic process GO:1901565 264 0.193
blood vessel morphogenesis GO:0048514 285 0.193
regulation of jak stat cascade GO:0046425 34 0.192
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.192
Mouse
photoreceptor cell differentiation GO:0046530 52 0.190
actin filament polymerization GO:0030041 44 0.190
guanosine containing compound catabolic process GO:1901069 144 0.188
purine ribonucleotide metabolic process GO:0009150 290 0.186
bone resorption GO:0045453 38 0.185
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.184
spermatid development GO:0007286 108 0.183
myeloid cell homeostasis GO:0002262 114 0.182
Mouse
nuclear transport GO:0051169 139 0.182
positive regulation of lipid metabolic process GO:0045834 40 0.179
Mouse
phosphatidylinositol metabolic process GO:0046488 45 0.178
Mouse
heterotypic cell cell adhesion GO:0034113 7 0.176
positive regulation of secretion by cell GO:1903532 114 0.176
Mouse
negative regulation of immune effector process GO:0002698 55 0.176
myeloid cell activation involved in immune response GO:0002275 34 0.175
Mouse
camera type eye development GO:0043010 266 0.174
hematopoietic stem cell migration GO:0035701 1 0.174
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.172
fatty acid metabolic process GO:0006631 121 0.171
sensory perception of mechanical stimulus GO:0050954 107 0.171
organelle fission GO:0048285 170 0.171
second messenger mediated signaling GO:0019932 73 0.169
cytosolic calcium ion transport GO:0060401 48 0.167
Mouse
regulation of phosphatidylinositol 3 kinase activity GO:0043551 14 0.166
Mouse
negative regulation of growth GO:0045926 99 0.164
Mouse Fly
multicellular organismal homeostasis GO:0048871 164 0.163
Mouse
cellular homeostasis GO:0019725 240 0.162
Mouse
regulation of metal ion transport GO:0010959 106 0.161
Mouse
regulation of erk1 and erk2 cascade GO:0070372 71 0.161
Mouse
negative regulation of cell proliferation GO:0008285 296 0.160
Mouse
tissue remodeling GO:0048771 102 0.159
Mouse
carboxylic acid biosynthetic process GO:0046394 86 0.159
positive regulation of immunoglobulin mediated immune response GO:0002891 26 0.158
negative regulation of protein tyrosine kinase activity GO:0061099 3 0.156
positive regulation of translational initiation GO:0045948 4 0.156
positive regulation of apoptotic process GO:0043065 217 0.155
Mouse
tissue migration GO:0090130 68 0.154
establishment of mitotic spindle localization GO:0040001 12 0.153
Worm
negative regulation of nervous system development GO:0051961 156 0.153
Fly
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.152
Mouse
activation of janus kinase activity GO:0042976 2 0.152
regulation of tyrosine phosphorylation of stat protein GO:0042509 20 0.150
Mouse
exocytosis GO:0006887 121 0.148
Mouse
myeloid cell differentiation GO:0030099 233 0.146
Mouse
tolerance induction to self antigen GO:0002513 4 0.146
Mouse
regulation of cell motility GO:2000145 236 0.145
Mouse
negative regulation of cell adhesion GO:0007162 45 0.144
ribonucleotide metabolic process GO:0009259 291 0.144
mitotic cell cycle GO:0000278 195 0.141
Worm
phosphatidylinositol biosynthetic process GO:0006661 15 0.140
positive regulation of innate immune response GO:0045089 80 0.139
Mouse
epidermal growth factor receptor signaling pathway GO:0007173 28 0.139
regulation of cell growth GO:0001558 91 0.139
detection of mechanical stimulus involved in sensory perception GO:0050974 23 0.138
cell growth GO:0016049 130 0.136
negative regulation of b cell proliferation GO:0030889 13 0.133
Mouse
monocarboxylic acid biosynthetic process GO:0072330 61 0.132
synaptic growth at neuromuscular junction GO:0051124 6 0.132
Fly
neutrophil activation involved in immune response GO:0002283 8 0.131
glycerolipid metabolic process GO:0046486 122 0.129
Mouse
regulation of nuclear division GO:0051783 56 0.129
nucleoside metabolic process GO:0009116 246 0.129
regulation of purine nucleotide metabolic process GO:1900542 169 0.128
response to platelet derived growth factor GO:0036119 6 0.128
regulation of hemostasis GO:1900046 28 0.127
Mouse
hexose transport GO:0008645 56 0.126
Mouse
organophosphate biosynthetic process GO:0090407 122 0.125
epithelium migration GO:0090132 63 0.123
regulation of neuron differentiation GO:0045664 281 0.122
filtration diaphragm assembly GO:0036058 1 0.122
Fly
ribonucleoside catabolic process GO:0042454 206 0.121
peptidyl serine modification GO:0018209 83 0.121
phosphatidylinositol phosphorylation GO:0046854 23 0.120
Mouse
cellular zinc ion homeostasis GO:0006882 9 0.120
ion transmembrane transport GO:0034220 361 0.119
positive regulation of t cell anergy GO:0002669 4 0.119
positive regulation of dendritic cell apoptotic process GO:2000670 3 0.118
Mouse
regulation of cytokine secretion GO:0050707 61 0.118
Mouse
digestive tract development GO:0048565 190 0.117
Zebrafish Mouse Worm
regulation of mast cell proliferation GO:0070666 4 0.117
Mouse
neural retina development GO:0003407 41 0.117
positive regulation of stress activated mapk cascade GO:0032874 48 0.115
positive regulation of endothelial cell migration GO:0010595 12 0.115
gtp catabolic process GO:0006184 143 0.113
hematopoietic progenitor cell differentiation GO:0002244 143 0.112
cyclic nucleotide biosynthetic process GO:0009190 44 0.112
regulation of transmembrane transport GO:0034762 128 0.111
regulation of protein catabolic process GO:0042176 108 0.111
regulation of lipid metabolic process GO:0019216 118 0.110
Mouse
compound eye development GO:0048749 1 0.109
regulation of nucleoside metabolic process GO:0009118 130 0.109

Fyn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org