Mus musculus

17 known processes

Ppia

peptidylprolyl isomerase A

(Aliases: CyP-18,Cphn,2700098C05,CypA)

Ppia biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleobase containing small molecule metabolic process GO:0055086 352 0.337
cellular nitrogen compound catabolic process GO:0044270 280 0.325
response to oxidative stress GO:0006979 123 0.304
cellular response to interleukin 4 GO:0071353 21 0.298
cation transport GO:0006812 399 0.286
nucleotide metabolic process GO:0009117 332 0.274
purine nucleotide metabolic process GO:0006163 302 0.272
glycosyl compound metabolic process GO:1901657 246 0.241
purine ribonucleoside metabolic process GO:0046128 241 0.240
purine containing compound metabolic process GO:0072521 311 0.227
aromatic compound catabolic process GO:0019439 286 0.215
ribonucleotide metabolic process GO:0009259 291 0.215
purine nucleotide catabolic process GO:0006195 211 0.209
purine containing compound catabolic process GO:0072523 213 0.200
dna repair GO:0006281 107 0.198
nucleoside triphosphate metabolic process GO:0009141 230 0.194
carbohydrate derivative catabolic process GO:1901136 231 0.177
purine nucleoside catabolic process GO:0006152 205 0.175
nucleoside phosphate metabolic process GO:0006753 338 0.167
ribose phosphate metabolic process GO:0019693 291 0.154
nucleoside metabolic process GO:0009116 246 0.152
purine ribonucleotide metabolic process GO:0009150 290 0.151
organophosphate catabolic process GO:0046434 232 0.143
heterocycle catabolic process GO:0046700 280 0.141
cellular response to oxidative stress GO:0034599 76 0.133
ribonucleotide catabolic process GO:0009261 208 0.126
nucleoside phosphate catabolic process GO:1901292 222 0.124
purine ribonucleotide catabolic process GO:0009154 208 0.121
nucleoside triphosphate catabolic process GO:0009143 205 0.120
translation GO:0006412 93 0.117
cellular amino acid metabolic process GO:0006520 103 0.115
organelle assembly GO:0070925 177 0.112
hexose catabolic process GO:0019320 3 0.111
ion transmembrane transport GO:0034220 361 0.106
cellular chemical homeostasis GO:0055082 215 0.105
nucleotide catabolic process GO:0009166 217 0.102
organic cyclic compound catabolic process GO:1901361 295 0.099
cellular response to cytokine stimulus GO:0071345 189 0.099
ribonucleoside metabolic process GO:0009119 245 0.095
chromatin organization GO:0006325 206 0.090
gonad development GO:0008406 141 0.090
cellular ketone metabolic process GO:0042180 84 0.089
purine ribonucleoside catabolic process GO:0046130 205 0.088
dna metabolic process GO:0006259 303 0.088
regulation of cellular ketone metabolic process GO:0010565 66 0.086
cytoplasmic transport GO:0016482 234 0.085
purine nucleoside metabolic process GO:0042278 241 0.083
oxidation reduction process GO:0055114 342 0.083
microtubule cytoskeleton organization GO:0000226 157 0.083
glycosyl compound catabolic process GO:1901658 206 0.081
cellular homeostasis GO:0019725 240 0.080
guanosine containing compound metabolic process GO:1901068 144 0.078
positive regulation of cellular amine metabolic process GO:0033240 5 0.072
organonitrogen compound catabolic process GO:1901565 264 0.071
actin filament based movement GO:0030048 23 0.071
covalent chromatin modification GO:0016569 163 0.070
nucleoside catabolic process GO:0009164 206 0.068
protein localization to organelle GO:0033365 185 0.068
nucleobase containing compound transport GO:0015931 27 0.068
ribonucleoside catabolic process GO:0042454 206 0.066
retina homeostasis GO:0001895 23 0.065
transmembrane transport GO:0055085 412 0.065
inorganic ion transmembrane transport GO:0098660 234 0.064
response to epidermal growth factor GO:0070849 4 0.063
response to organonitrogen compound GO:0010243 246 0.063
positive regulation of apoptotic process GO:0043065 217 0.062
positive regulation of nucleotide metabolic process GO:0045981 114 0.061
positive regulation of programmed cell death GO:0043068 218 0.060
cation transmembrane transport GO:0098655 266 0.059
response to amino acid GO:0043200 37 0.059
translational elongation GO:0006414 12 0.059
regulation of nucleotide metabolic process GO:0006140 169 0.058
regulation of body fluid levels GO:0050878 162 0.058
skeletal muscle thin filament assembly GO:0030240 2 0.057
nucleocytoplasmic transport GO:0006913 139 0.057
regulation of cellular amino acid metabolic process GO:0006521 5 0.057
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.056
ribonucleoside triphosphate metabolic process GO:0009199 220 0.056
nuclear transport GO:0051169 139 0.056
amine metabolic process GO:0009308 45 0.054
negative regulation of phagocytosis GO:0050765 4 0.054
response to acid chemical GO:0001101 111 0.054
regulation of anatomical structure size GO:0090066 178 0.054
positive regulation of hydrolase activity GO:0051345 148 0.053
cellular component assembly involved in morphogenesis GO:0010927 139 0.052
regulation of intracellular transport GO:0032386 159 0.052
cellular amine metabolic process GO:0044106 44 0.051
purine nucleoside triphosphate metabolic process GO:0009144 226 0.051
protein secretion GO:0009306 111 0.051
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.050
cellular response to dna damage stimulus GO:0006974 207 0.048
response to hyperoxia GO:0055093 2 0.047
purine nucleotide biosynthetic process GO:0006164 65 0.047
cellular ion homeostasis GO:0006873 165 0.044
inorganic cation transmembrane transport GO:0098662 207 0.043
mitotic cytokinesis GO:0000281 4 0.043
neural tube formation GO:0001841 108 0.043
response to inorganic substance GO:0010035 96 0.043
regulation of cellular catabolic process GO:0031329 242 0.042
mitotic cell cycle GO:0000278 195 0.042
positive regulation of protein modification process GO:0031401 299 0.042
response to organic cyclic compound GO:0014070 198 0.042
cell adhesion GO:0007155 329 0.042
purine nucleoside monophosphate catabolic process GO:0009128 58 0.041
positive regulation of cell death GO:0010942 224 0.040
purine nucleoside triphosphate catabolic process GO:0009146 203 0.040
myotube differentiation GO:0014902 105 0.040
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.040
centrosome cycle GO:0007098 23 0.038
regulation of homeostatic process GO:0032844 182 0.038
regulation of protein kinase activity GO:0045859 232 0.038
ribonucleoside triphosphate catabolic process GO:0009203 199 0.038
skeletal muscle fiber development GO:0048741 58 0.037
nitrogen compound transport GO:0071705 271 0.036
multicellular organism growth GO:0035264 161 0.036
posttranscriptional regulation of gene expression GO:0010608 155 0.036
regulation of organelle organization GO:0033043 289 0.036
regulation of cellular component biogenesis GO:0044087 181 0.035
cellular metal ion homeostasis GO:0006875 151 0.035
organophosphate biosynthetic process GO:0090407 122 0.035
cellular response to epidermal growth factor stimulus GO:0071364 4 0.035
histone modification GO:0016570 159 0.034
purine containing compound biosynthetic process GO:0072522 70 0.034
establishment or maintenance of cell polarity GO:0007163 86 0.034
muscle cell differentiation GO:0042692 261 0.033
protein targeting GO:0006605 143 0.033
positive regulation of organelle organization GO:0010638 128 0.033
striated muscle tissue development GO:0014706 293 0.033
posttranscriptional gene silencing by rna GO:0035194 10 0.033
mitotic cell cycle process GO:1903047 159 0.033
carbohydrate derivative biosynthetic process GO:1901137 183 0.032
calcium ion homeostasis GO:0055074 127 0.032
microtubule based process GO:0007017 236 0.032
cellular macromolecule catabolic process GO:0044265 206 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.031
cytokinetic process GO:0032506 2 0.031
skeletal muscle organ development GO:0060538 163 0.031
gtp metabolic process GO:0046039 144 0.030
divalent inorganic cation homeostasis GO:0072507 138 0.030
response to amine GO:0014075 16 0.030
ribonucleoside monophosphate metabolic process GO:0009161 80 0.029
intracellular protein transport GO:0006886 204 0.029
lymphocyte proliferation GO:0046651 164 0.029
blood coagulation GO:0007596 76 0.029
substantia nigra development GO:0021762 2 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
regulation of nucleocytoplasmic transport GO:0046822 73 0.028
cellular calcium ion homeostasis GO:0006874 119 0.028
nuclear export GO:0051168 34 0.028
regulation of cellular amine metabolic process GO:0033238 20 0.028
cellular response to extracellular stimulus GO:0031668 81 0.027
actin filament organization GO:0007015 113 0.027
development of primary sexual characteristics GO:0045137 143 0.027
response to growth factor GO:0070848 198 0.026
protein import GO:0017038 101 0.026
peptidyl amino acid modification GO:0018193 336 0.026
Human
actin mediated cell contraction GO:0070252 15 0.026
skeletal myofibril assembly GO:0014866 4 0.025
protein localization to nucleus GO:0034504 121 0.025
actin filament polymerization GO:0030041 44 0.025
rna interference GO:0016246 2 0.025
proteasomal protein catabolic process GO:0010498 98 0.025
regulation of blood pressure GO:0008217 93 0.025
heart morphogenesis GO:0003007 178 0.025
response to alcohol GO:0097305 48 0.025
ketone catabolic process GO:0042182 3 0.025
cytosolic calcium ion homeostasis GO:0051480 70 0.024
translational initiation GO:0006413 24 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
neural tube development GO:0021915 160 0.024
metal ion homeostasis GO:0055065 189 0.024
cyclic nucleotide metabolic process GO:0009187 59 0.024
hemostasis GO:0007599 78 0.024
anion transport GO:0006820 177 0.024
wound healing GO:0042060 157 0.023
ubiquitin dependent protein catabolic process GO:0006511 129 0.023
muscle tissue development GO:0060537 308 0.023
cellular divalent inorganic cation homeostasis GO:0072503 127 0.023
circulatory system process GO:0003013 197 0.023
protein depolymerization GO:0051261 34 0.023
monocarboxylic acid metabolic process GO:0032787 191 0.023
translesion synthesis GO:0019985 1 0.023
apoptotic signaling pathway GO:0097190 306 0.023
positive regulation of protein phosphorylation GO:0001934 242 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
blood circulation GO:0008015 195 0.022
morphogenesis of embryonic epithelium GO:0016331 159 0.022
organonitrogen compound biosynthetic process GO:1901566 192 0.022
locomotory behavior GO:0007626 195 0.022
regulation of purine nucleotide metabolic process GO:1900542 169 0.022
guanosine containing compound catabolic process GO:1901069 144 0.022
tissue homeostasis GO:0001894 115 0.022
ras protein signal transduction GO:0007265 77 0.022
cardiac muscle tissue development GO:0048738 130 0.022
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.022
cellular response to growth factor stimulus GO:0071363 197 0.022
regulation of protein localization GO:0032880 231 0.022
Human
cofactor transport GO:0051181 4 0.022
l ascorbic acid metabolic process GO:0019852 4 0.021
receptor mediated endocytosis GO:0006898 51 0.021
meiotic cell cycle GO:0051321 122 0.021
leukocyte differentiation GO:0002521 342 0.021
cellular protein complex assembly GO:0043623 116 0.021
glucose homeostasis GO:0042593 128 0.021
peptidyl lysine modification GO:0018205 77 0.021
regulation of ion transport GO:0043269 215 0.021
carboxylic acid biosynthetic process GO:0046394 86 0.021
fertilization GO:0009566 127 0.021
gland development GO:0048732 330 0.020
oocyte axis specification GO:0007309 2 0.020
muscle contraction GO:0006936 101 0.020
nucleoside phosphate biosynthetic process GO:1901293 79 0.020
purine nucleoside biosynthetic process GO:0042451 19 0.020
primary neural tube formation GO:0014020 95 0.020
regulation of translational elongation GO:0006448 4 0.020
regulation of mapk cascade GO:0043408 248 0.020
regulation of transmembrane transport GO:0034762 128 0.020
engulfment of apoptotic cell GO:0043652 3 0.019
regulation of transporter activity GO:0032409 57 0.019
single organism nuclear import GO:1902593 95 0.019
response to corticosterone GO:0051412 1 0.019
carbohydrate metabolic process GO:0005975 230 0.019
regulation of cytoskeleton organization GO:0051493 122 0.019
g protein coupled receptor signaling pathway GO:0007186 243 0.019
regulation of tube size GO:0035150 57 0.019
regulation of protein import into nucleus translocation GO:0033158 2 0.019
asymmetric stem cell division GO:0098722 3 0.019
gtp catabolic process GO:0006184 143 0.019
protein import into nucleus GO:0006606 95 0.019
positive regulation of protein kinase activity GO:0045860 144 0.018
carbohydrate biosynthetic process GO:0016051 74 0.018
purine nucleoside monophosphate metabolic process GO:0009126 81 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.018
regulation of actin filament based process GO:0032970 99 0.018
mapk cascade GO:0000165 281 0.018
positive regulation of protein catabolic process GO:0045732 60 0.018
pancreas development GO:0031016 57 0.018
sensory perception GO:0007600 245 0.018
ribonucleoside monophosphate catabolic process GO:0009158 57 0.018
4 hydroxyproline metabolic process GO:0019471 5 0.018
regulation of cytoplasmic transport GO:1903649 112 0.018
rna localization GO:0006403 23 0.018
midbrain development GO:0030901 35 0.018
regulation of hormone levels GO:0010817 211 0.017
chromatin modification GO:0016568 187 0.017
carbohydrate homeostasis GO:0033500 128 0.017
cardiocyte differentiation GO:0035051 87 0.017
endocytosis GO:0006897 168 0.017
forebrain development GO:0030900 302 0.017
regulation of cellular response to stress GO:0080135 159 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
Human
epithelial cell proliferation GO:0050673 174 0.017
ribose phosphate biosynthetic process GO:0046390 59 0.017
posttranscriptional gene silencing GO:0016441 10 0.017
actin cytoskeleton organization GO:0030036 220 0.017
rna splicing GO:0008380 54 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
positive regulation of cellular catabolic process GO:0031331 148 0.016
protein acylation GO:0043543 64 0.016
regulation of membrane potential GO:0042391 192 0.016
internal peptidyl lysine acetylation GO:0018393 42 0.016
regulation of dna binding GO:0051101 39 0.016
spindle assembly involved in mitosis GO:0090307 4 0.016
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.016
regulation of cell activation GO:0050865 289 0.016
muscle fiber development GO:0048747 76 0.016
peptidyl serine phosphorylation GO:0018105 74 0.016
regulation of actin cytoskeleton organization GO:0032956 84 0.016
cellular response to lipid GO:0071396 145 0.015
ribonucleoside biosynthetic process GO:0042455 21 0.015
internal protein amino acid acetylation GO:0006475 42 0.015
response to metal ion GO:0010038 47 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
tube formation GO:0035148 140 0.015
muscle cell development GO:0055001 133 0.015
embryonic epithelial tube formation GO:0001838 130 0.015
gene silencing by rna GO:0031047 19 0.015
epithelial tube formation GO:0072175 130 0.015
energy derivation by oxidation of organic compounds GO:0015980 77 0.015
nuclear division GO:0000280 158 0.015
anatomical structure homeostasis GO:0060249 145 0.015
chronological cell aging GO:0001300 1 0.015
cell type specific apoptotic process GO:0097285 268 0.015
cellular respiration GO:0045333 38 0.015
cation homeostasis GO:0055080 212 0.015
protein catabolic process GO:0030163 221 0.014
thermosensory behavior GO:0040040 1 0.014
smooth muscle contraction GO:0006939 44 0.014
membrane organization GO:0061024 245 0.014
divalent inorganic cation transport GO:0072511 178 0.014
regulation of cellular response to oxidative stress GO:1900407 19 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
regulation of ion homeostasis GO:2000021 64 0.014
vascular smooth muscle contraction GO:0014829 5 0.014
multi multicellular organism process GO:0044706 109 0.014
regulation of cell motility GO:2000145 236 0.014
ribonucleotide biosynthetic process GO:0009260 59 0.014
ribonucleoprotein complex subunit organization GO:0071826 28 0.014
regulation of protein targeting GO:1903533 61 0.014
oocyte construction GO:0007308 2 0.014
muscle system process GO:0003012 141 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
epidermis development GO:0008544 187 0.014
regulation of cellular component size GO:0032535 121 0.013
regulation of hydrolase activity GO:0051336 246 0.013
purine ribonucleoside biosynthetic process GO:0046129 19 0.013
cellular response to glucose stimulus GO:0071333 45 0.013
myotube cell development GO:0014904 60 0.013
nucleotide biosynthetic process GO:0009165 78 0.013
protein maturation GO:0051604 176 0.013
maintenance of location GO:0051235 89 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
regulation of cell migration GO:0030334 219 0.013
regulation of actin filament polymerization GO:0030833 38 0.013
positive regulation of growth GO:0045927 104 0.013
muscle tissue morphogenesis GO:0060415 53 0.013
organic anion transport GO:0015711 137 0.013
water soluble vitamin biosynthetic process GO:0042364 3 0.013
stem cell maintenance GO:0019827 130 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
sequestering of metal ion GO:0051238 19 0.013
macromolecule catabolic process GO:0009057 281 0.013
myeloid cell differentiation GO:0030099 233 0.013
cellular response to hexose stimulus GO:0071331 47 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
glycogen biosynthetic process GO:0005978 14 0.012
nuclear import GO:0051170 95 0.012
response to mineralocorticoid GO:0051385 1 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
asymmetric neuroblast division GO:0055059 1 0.012
ribosomal large subunit assembly GO:0000027 2 0.012
positive regulation of kinase activity GO:0033674 155 0.012
extracellular structure organization GO:0043062 148 0.012
regulation of binding GO:0051098 111 0.012
glucose metabolic process GO:0006006 92 0.012
regulation of glucose metabolic process GO:0010906 60 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
camp catabolic process GO:0006198 4 0.012
response to radiation GO:0009314 165 0.012
generation of precursor metabolites and energy GO:0006091 103 0.012
leukocyte mediated immunity GO:0002443 174 0.012
stem cell development GO:0048864 219 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
glycosyl compound biosynthetic process GO:1901659 21 0.012
regulation of nucleotide biosynthetic process GO:0030808 34 0.012
positive regulation of nucleotide catabolic process GO:0030813 88 0.012
regulation of immunological synapse formation GO:2000520 2 0.012
purine ribonucleotide biosynthetic process GO:0009152 59 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.011
peptidyl lysine acetylation GO:0018394 45 0.011
regulation of muscle tissue development GO:1901861 97 0.011
stress activated mapk cascade GO:0051403 80 0.011
organelle fission GO:0048285 170 0.011
response to thyroid hormone GO:0097066 2 0.011
carboxylic acid catabolic process GO:0046395 51 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
nucleic acid transport GO:0050657 18 0.011
activation of adenylate cyclase activity GO:0007190 4 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
regulation of cation channel activity GO:2001257 22 0.011
negative regulation of leukocyte differentiation GO:1902106 51 0.011
cytokinesis GO:0000910 17 0.011
positive regulation of cytoskeleton organization GO:0051495 49 0.011
vasoconstriction GO:0042310 27 0.011
meiotic nuclear division GO:0007126 115 0.011
regulation of proteolysis GO:0030162 164 0.011
ribosome biogenesis GO:0042254 20 0.011
regulation of blood vessel size GO:0050880 56 0.011
single fertilization GO:0007338 82 0.011
regulation of t cell activation GO:0050863 170 0.011
divalent metal ion transport GO:0070838 172 0.011
telencephalon development GO:0021537 186 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
cellular protein catabolic process GO:0044257 155 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.010
synaptic vesicle localization GO:0097479 59 0.010
genitalia development GO:0048806 37 0.010
cellular lipid metabolic process GO:0044255 323 0.010
cardiac muscle cell development GO:0055013 39 0.010
hematopoietic progenitor cell differentiation GO:0002244 143 0.010
adenine nucleotide transport GO:0051503 2 0.010
regulation of ion transmembrane transporter activity GO:0032412 54 0.010
regulation of phosphoprotein phosphatase activity GO:0043666 3 0.010
regulation of endocytosis GO:0030100 69 0.010
germ cell development GO:0007281 185 0.010

Ppia disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.051
nervous system disease DOID:863 0 0.051
sensory system disease DOID:0050155 0 0.033
auditory system disease DOID:2742 0 0.014
disease of metabolism DOID:0014667 0 0.010