Mus musculus

0 known processes

Ik

IK cytokine

(Aliases: MuRED)

Ik biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna splicing GO:0008380 54 0.410
microtubule cytoskeleton organization GO:0000226 157 0.292
male gamete generation GO:0048232 285 0.287
spermatogenesis GO:0007283 284 0.264
rna splicing via transesterification reactions GO:0000375 43 0.257
stem cell differentiation GO:0048863 268 0.249
nucleoside phosphate metabolic process GO:0006753 338 0.248
cellularization GO:0007349 1 0.212
endocytosis GO:0006897 168 0.196
atp catabolic process GO:0006200 55 0.187
regulation of vesicle mediated transport GO:0060627 139 0.177
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.151
spermatid differentiation GO:0048515 115 0.150
meiotic nuclear division GO:0007126 115 0.141
purine nucleoside metabolic process GO:0042278 241 0.140
posttranscriptional gene silencing GO:0016441 10 0.139
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.139
rna processing GO:0006396 105 0.117
rna interference GO:0016246 2 0.112
spermatid development GO:0007286 108 0.111
nucleoside catabolic process GO:0009164 206 0.107
cell division GO:0051301 120 0.102
nucleoside phosphate catabolic process GO:1901292 222 0.095
organic cyclic compound catabolic process GO:1901361 295 0.091
negative regulation of cell proliferation GO:0008285 296 0.090
posttranscriptional gene silencing by rna GO:0035194 10 0.086
apoptotic signaling pathway GO:0097190 306 0.086
regulation of cell cycle GO:0051726 281 0.084
purine nucleotide catabolic process GO:0006195 211 0.083
ribonucleoside monophosphate catabolic process GO:0009158 57 0.082
nucleoside monophosphate metabolic process GO:0009123 85 0.080
mrna processing GO:0006397 63 0.079
nucleoside triphosphate catabolic process GO:0009143 205 0.077
nucleoside monophosphate catabolic process GO:0009125 59 0.075
nucleoside triphosphate metabolic process GO:0009141 230 0.071
purine nucleoside triphosphate catabolic process GO:0009146 203 0.068
cellular response to dna damage stimulus GO:0006974 207 0.066
mrna metabolic process GO:0016071 84 0.065
cellular macromolecule catabolic process GO:0044265 206 0.065
glycosyl compound catabolic process GO:1901658 206 0.064
sperm individualization GO:0007291 1 0.064
ribonucleoside monophosphate metabolic process GO:0009161 80 0.063
purine nucleoside monophosphate catabolic process GO:0009128 58 0.062
nucleotide catabolic process GO:0009166 217 0.062
molting cycle GO:0042303 90 0.062
purine ribonucleoside metabolic process GO:0046128 241 0.061
ribonucleoside metabolic process GO:0009119 245 0.061
membrane organization GO:0061024 245 0.060
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.060
purine nucleoside monophosphate metabolic process GO:0009126 81 0.059
cellular nitrogen compound catabolic process GO:0044270 280 0.058
endomembrane system organization GO:0010256 147 0.058
purine nucleoside triphosphate metabolic process GO:0009144 226 0.057
protein localization to organelle GO:0033365 185 0.056
digestive tract morphogenesis GO:0048546 147 0.055
skeletal muscle cell differentiation GO:0035914 66 0.054
organelle assembly GO:0070925 177 0.054
heterocycle catabolic process GO:0046700 280 0.053
positive regulation of proteolysis GO:0045862 85 0.050
positive regulation of growth GO:0045927 104 0.050
nucleotide metabolic process GO:0009117 332 0.049
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.048
mitotic cell cycle process GO:1903047 159 0.048
regulation of hydrolase activity GO:0051336 246 0.048
cytoplasmic transport GO:0016482 234 0.047
striated muscle tissue development GO:0014706 293 0.045
neuron apoptotic process GO:0051402 142 0.045
ribonucleoside triphosphate metabolic process GO:0009199 220 0.045
purine ribonucleotide metabolic process GO:0009150 290 0.045
mrna splicing via spliceosome GO:0000398 43 0.045
germ cell development GO:0007281 185 0.042
ribonucleoside catabolic process GO:0042454 206 0.042
atp metabolic process GO:0046034 75 0.042
ribonucleotide metabolic process GO:0009259 291 0.041
purine nucleoside catabolic process GO:0006152 205 0.041
positive regulation of protein catabolic process GO:0045732 60 0.040
ribonucleoside triphosphate catabolic process GO:0009203 199 0.040
organophosphate catabolic process GO:0046434 232 0.040
microtubule based process GO:0007017 236 0.039
protein neddylation GO:0045116 1 0.039
ribose phosphate metabolic process GO:0019693 291 0.036
maintenance of location GO:0051235 89 0.035
negative regulation of cell cycle phase transition GO:1901988 48 0.035
digestive tract development GO:0048565 190 0.035
purine ribonucleotide catabolic process GO:0009154 208 0.035
nucleoside metabolic process GO:0009116 246 0.034
positive regulation of hydrolase activity GO:0051345 148 0.034
axonogenesis GO:0007409 274 0.033
organonitrogen compound catabolic process GO:1901565 264 0.032
regulation of mitotic cell cycle phase transition GO:1901990 73 0.032
negative regulation of molecular function GO:0044092 258 0.030
dna repair GO:0006281 107 0.030
purine containing compound catabolic process GO:0072523 213 0.029
stem cell development GO:0048864 219 0.029
positive regulation of dna templated transcription elongation GO:0032786 2 0.029
dna metabolic process GO:0006259 303 0.029
purine ribonucleoside catabolic process GO:0046130 205 0.029
skeletal muscle organ development GO:0060538 163 0.027
negative regulation of protein metabolic process GO:0051248 282 0.027
peptidyl amino acid modification GO:0018193 336 0.027
regulation of cell cycle phase transition GO:1901987 77 0.027
carbohydrate derivative catabolic process GO:1901136 231 0.026
organelle fission GO:0048285 170 0.026
fertilization GO:0009566 127 0.026
regulation of organelle organization GO:0033043 289 0.026
phagosome maturation GO:0090382 4 0.026
regulation of mitotic cell cycle GO:0007346 126 0.025
lipid localization GO:0010876 126 0.025
macromolecule methylation GO:0043414 120 0.024
chromatin organization GO:0006325 206 0.024
ribonucleotide catabolic process GO:0009261 208 0.024
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.023
regulation of cell growth GO:0001558 91 0.023
muscle tissue development GO:0060537 308 0.023
regulation of cell projection organization GO:0031344 206 0.022
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.022
regulation of cysteine type endopeptidase activity GO:2000116 65 0.022
cell type specific apoptotic process GO:0097285 268 0.022
regulation of response to dna damage stimulus GO:2001020 34 0.021
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.021
regulation of cellular response to growth factor stimulus GO:0090287 82 0.021
cell adhesion GO:0007155 329 0.021
regulation of cell cycle process GO:0010564 160 0.021
purine containing compound metabolic process GO:0072521 311 0.020
cellular response to sterol depletion GO:0071501 4 0.020
methylation GO:0032259 134 0.019
regulation of mrna splicing via spliceosome GO:0048024 32 0.019
regulation of cellular response to stress GO:0080135 159 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.019
nitrogen compound transport GO:0071705 271 0.019
gene silencing by rna GO:0031047 19 0.019
nuclear division GO:0000280 158 0.019
mitotic cell cycle GO:0000278 195 0.018
digestive system development GO:0055123 200 0.018
negative regulation of apoptotic signaling pathway GO:2001234 104 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 1 0.018
cell growth GO:0016049 130 0.018
aromatic compound catabolic process GO:0019439 286 0.018
cation transmembrane transport GO:0098655 266 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.017
maternal determination of anterior posterior axis embryo GO:0008358 2 0.017
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.017
intracellular mrna localization GO:0008298 4 0.017
dna conformation change GO:0071103 37 0.017
regulation of protein maturation GO:1903317 96 0.016
negative regulation of synapse assembly GO:0051964 3 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.015
vesicle organization GO:0016050 60 0.015
developmental maturation GO:0021700 193 0.015
synaptic transmission GO:0007268 329 0.015
maintenance of protein location in nucleus GO:0051457 2 0.015
protein retention in golgi apparatus GO:0045053 1 0.015
regulation of androgen receptor signaling pathway GO:0060765 3 0.015
gastrulation GO:0007369 116 0.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.015
response to peptide GO:1901652 136 0.015
microtubule polymerization or depolymerization GO:0031109 26 0.015
transmembrane transport GO:0055085 412 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
negative regulation of dna replication GO:0008156 4 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
genitalia development GO:0048806 37 0.014
negative regulation of cell motility GO:2000146 61 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
negative regulation of mitotic cell cycle GO:0045930 58 0.014
cellular protein catabolic process GO:0044257 155 0.013
rna splicing via endonucleolytic cleavage and ligation GO:0000394 1 0.013
protein maturation GO:0051604 176 0.013
signal transduction by p53 class mediator GO:0072331 51 0.013
response to insulin GO:0032868 100 0.013
ion transmembrane transport GO:0034220 361 0.013
regulation of protein stability GO:0031647 52 0.013
regulation of proteolysis GO:0030162 164 0.013
single fertilization GO:0007338 82 0.013
gtp catabolic process GO:0006184 143 0.013
ncrna processing GO:0034470 26 0.013
single organism cell adhesion GO:0098602 156 0.013
negative regulation of hydrolase activity GO:0051346 71 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
response to organonitrogen compound GO:0010243 246 0.012
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.012
muscle fiber development GO:0048747 76 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
oocyte anterior posterior axis specification GO:0007314 2 0.012
regulation of kinase activity GO:0043549 249 0.012
regulation of body fluid levels GO:0050878 162 0.012
negative regulation of cell projection organization GO:0031345 56 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
trna processing GO:0008033 11 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.011
oocyte axis specification GO:0007309 2 0.011
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.011
gonad development GO:0008406 141 0.011
regulation of stress activated mapk cascade GO:0032872 69 0.011
protein processing GO:0016485 163 0.011
macromolecule catabolic process GO:0009057 281 0.011
positive regulation of glial cell proliferation GO:0060252 4 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.011
negative regulation of protein maturation GO:1903318 79 0.011
positive regulation of cell cycle g1 s phase transition GO:1902808 9 0.011
regulation of protein localization GO:0032880 231 0.011
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.011
positive regulation of transferase activity GO:0051347 167 0.011
stem cell maintenance GO:0019827 130 0.010
regulation of neuron differentiation GO:0045664 281 0.010
regulation of cell cycle g1 s phase transition GO:1902806 35 0.010
regulation of cellular catabolic process GO:0031329 242 0.010
epithelial cilium movement GO:0003351 12 0.010
cell maturation GO:0048469 127 0.010
gene silencing GO:0016458 38 0.010
ncrna 3 end processing GO:0043628 2 0.010

Ik disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.051
nervous system disease DOID:863 0 0.051
myopathy DOID:423 0 0.010
muscular disease DOID:0080000 0 0.010
muscular dystrophy DOID:9884 0 0.010
limb girdle muscular dystrophy DOID:11724 0 0.010
musculoskeletal system disease DOID:17 0 0.010
muscle tissue disease DOID:66 0 0.010