Mus musculus

53 known processes

Plxna1

plexin A1

(Aliases: mKIAA4053,NOV,2600013D04Rik,Plxn1,KIAA4053)

Plxna1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
branchiomotor neuron axon guidance GO:0021785 7 0.995
Mouse
negative regulation of axon guidance GO:1902668 8 0.987
Mouse
dichotomous subdivision of terminal units involved in salivary gland branching GO:0060666 5 0.985
trunk neural crest cell migration GO:0036484 4 0.967
neuron projection extension GO:1990138 64 0.960
Mouse
ras protein signal transduction GO:0007265 77 0.941
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.940
gtp catabolic process GO:0006184 143 0.939
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.937
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.923
Mouse
glycosyl compound catabolic process GO:1901658 206 0.922
Mouse
purine nucleotide metabolic process GO:0006163 302 0.913
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.906
Mouse
sympathetic neuron projection guidance GO:0097491 4 0.900
hypothalamus gonadotrophin releasing hormone neuron development GO:0021888 4 0.891
ribonucleoside triphosphate catabolic process GO:0009203 199 0.890
Mouse
semaphorin plexin signaling pathway involved in axon guidance GO:1902287 6 0.880
Mouse
regulation of axon extension GO:0030516 43 0.866
Mouse
ribonucleoside metabolic process GO:0009119 245 0.865
Mouse
guanosine containing compound metabolic process GO:1901068 144 0.864
Mouse
sympathetic neuron projection extension GO:0097490 4 0.860
semaphorin plexin signaling pathway involved in neuron projection guidance GO:1902285 6 0.853
Mouse
branching involved in salivary gland morphogenesis GO:0060445 26 0.852
guanosine containing compound catabolic process GO:1901069 144 0.852
Mouse
trunk segmentation GO:0035290 4 0.851
regulation of axon guidance GO:1902667 13 0.850
Mouse Fly
developmental cell growth GO:0048588 84 0.849
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.849
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.828
Mouse
cerebral cortex tangential migration using cell axon interactions GO:0021824 3 0.825
nucleotide metabolic process GO:0009117 332 0.818
Mouse
trigeminal nerve morphogenesis GO:0021636 6 0.818
Mouse
purine nucleotide catabolic process GO:0006195 211 0.818
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.813
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.810
Mouse Fly
semaphorin plexin signaling pathway involved in bone trabecula morphogenesis GO:1900220 2 0.809
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 226 0.798
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.796
negative chemotaxis GO:0050919 14 0.791
Mouse
heterocycle catabolic process GO:0046700 280 0.788
Mouse
nucleoside catabolic process GO:0009164 206 0.786
Mouse
purine nucleoside catabolic process GO:0006152 205 0.779
Mouse
regulation of purine nucleotide catabolic process GO:0033121 122 0.775
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.771
Mouse
ribonucleoside catabolic process GO:0042454 206 0.765
Mouse
regulation of gtp catabolic process GO:0033124 113 0.761
Mouse
ventral trunk neural crest cell migration GO:0036486 4 0.753
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.753
nucleoside triphosphate metabolic process GO:0009141 230 0.752
Mouse
positive regulation of nucleotide catabolic process GO:0030813 88 0.751
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.746
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.743
Mouse
regulation of cell size GO:0008361 72 0.734
Mouse
ribose phosphate metabolic process GO:0019693 291 0.732
Mouse
regulation of cellular catabolic process GO:0031329 242 0.729
Mouse
regulation of neuron projection development GO:0010975 169 0.725
Mouse Fly
glycosyl compound metabolic process GO:1901657 246 0.723
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.723
positive regulation of cellular amine metabolic process GO:0033240 5 0.718
regulation of nucleotide metabolic process GO:0006140 169 0.717
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.707
Mouse
axon extension involved in axon guidance GO:0048846 14 0.702
Mouse
purine nucleoside metabolic process GO:0042278 241 0.702
Mouse
regulation of rho gtpase activity GO:0032319 58 0.698
Mouse
facioacoustic ganglion development GO:1903375 3 0.694
facial nerve development GO:0021561 11 0.693
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.692
Mouse
positive regulation of ras gtpase activity GO:0032320 65 0.690
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.689
Mouse
anatomical structure arrangement GO:0048532 20 0.666
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.662
Mouse
gtp metabolic process GO:0046039 144 0.657
Mouse
aromatic compound catabolic process GO:0019439 286 0.652
Mouse
purine containing compound metabolic process GO:0072521 311 0.649
Mouse
purine containing compound catabolic process GO:0072523 213 0.647
Mouse
nucleotide catabolic process GO:0009166 217 0.645
Mouse
organophosphate catabolic process GO:0046434 232 0.641
Mouse
positive regulation of neuron projection development GO:0010976 79 0.639
Mouse
retinal ganglion cell axon guidance GO:0031290 18 0.637
purine ribonucleoside catabolic process GO:0046130 205 0.636
Mouse
positive regulation of rho gtpase activity GO:0032321 41 0.626
Mouse
positive regulation of cell development GO:0010720 237 0.624
Mouse
positive regulation of gtp catabolic process GO:0033126 85 0.624
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.622
purine nucleoside triphosphate catabolic process GO:0009146 203 0.611
Mouse
regulation of ras gtpase activity GO:0032318 88 0.607
Mouse
regulation of cell projection organization GO:0031344 206 0.600
Mouse Fly
ribonucleotide metabolic process GO:0009259 291 0.600
Mouse
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.566
Mouse
positive regulation of gtpase activity GO:0043547 85 0.560
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.554
negative regulation of chemotaxis GO:0050922 11 0.549
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.549
Mouse
establishment of organelle localization GO:0051656 122 0.546
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.543
Mouse
regulation of cell growth GO:0001558 91 0.538
Mouse
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.535
nucleoside metabolic process GO:0009116 246 0.535
Mouse
hypothalamic tangential migration using cell axon interactions GO:0021856 3 0.528
chemotaxis GO:0006935 247 0.526
Mouse Fly
carbohydrate derivative catabolic process GO:1901136 231 0.526
Mouse
regulation of purine nucleotide metabolic process GO:1900542 169 0.517
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.516
neuron recognition GO:0008038 25 0.513
Fly
axonogenesis GO:0007409 274 0.512
Mouse Fly
rho protein signal transduction GO:0007266 32 0.500
facial nerve morphogenesis GO:0021610 11 0.500
Mouse
mapk cascade GO:0000165 281 0.499
hypothalamus gonadotrophin releasing hormone neuron differentiation GO:0021886 4 0.489
cell adhesion GO:0007155 329 0.485
negative regulation of growth GO:0045926 99 0.481
Mouse
regulation of cellular response to growth factor stimulus GO:0090287 82 0.471
regulation of cell adhesion GO:0030155 154 0.465
cellular amino acid metabolic process GO:0006520 103 0.464
epidermis development GO:0008544 187 0.458
peptidyl amino acid modification GO:0018193 336 0.457
regulation of cellular amine metabolic process GO:0033238 20 0.451
neuron projection guidance GO:0097485 141 0.450
Mouse Fly
regulation of extent of cell growth GO:0061387 52 0.449
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.442
Mouse
regulation of hydrolase activity GO:0051336 246 0.436
Mouse
regionalization GO:0003002 337 0.436
Mouse
cell growth GO:0016049 130 0.436
Mouse
inner ear morphogenesis GO:0042472 101 0.436
facial nerve structural organization GO:0021612 10 0.435
Mouse
ribonucleotide catabolic process GO:0009261 208 0.430
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.428
Mouse
membrane organization GO:0061024 245 0.428
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.427
detection of external stimulus GO:0009581 61 0.427
regulation of protein kinase activity GO:0045859 232 0.424
positive regulation of nucleotide metabolic process GO:0045981 114 0.422
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.421
Mouse
blood vessel morphogenesis GO:0048514 285 0.418
Mouse
developmental maturation GO:0021700 193 0.415
Mouse
postganglionic parasympathetic nervous system development GO:0021784 2 0.413
Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.401
Mouse
angiogenesis GO:0001525 201 0.401
Mouse
stem cell differentiation GO:0048863 268 0.397
positive regulation of protein modification process GO:0031401 299 0.386
regulation of nucleoside metabolic process GO:0009118 130 0.384
Mouse
intracellular protein transport GO:0006886 204 0.380
forebrain development GO:0030900 302 0.376
Mouse
salivary gland morphogenesis GO:0007435 33 0.373
regulation of cell motility GO:2000145 236 0.366
dendrite development GO:0016358 115 0.358
trigeminal nerve structural organization GO:0021637 6 0.355
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.346
Mouse
glycoprotein biosynthetic process GO:0009101 89 0.338
regulation of mapk cascade GO:0043408 248 0.333
regulation of cell migration GO:0030334 219 0.321
motor neuron axon guidance GO:0008045 26 0.321
Mouse
anatomical structure maturation GO:0071695 49 0.320
Mouse
regulation of neuron differentiation GO:0045664 281 0.320
Mouse Fly
branching morphogenesis of an epithelial tube GO:0048754 159 0.318
Mouse
organelle localization GO:0051640 179 0.317
Mouse
carbohydrate metabolic process GO:0005975 230 0.317
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.315
amine metabolic process GO:0009308 45 0.312
response to light stimulus GO:0009416 135 0.310
exocytosis GO:0006887 121 0.308
bone development GO:0060348 120 0.308
Mouse
negative regulation of neuron projection development GO:0010977 50 0.307
Mouse
purine containing compound biosynthetic process GO:0072522 70 0.304
cellular ketone metabolic process GO:0042180 84 0.299
regulation of nucleotide catabolic process GO:0030811 122 0.295
Mouse
regulation of organelle organization GO:0033043 289 0.295
Mouse
protein localization to nucleus GO:0034504 121 0.293
cellular chemical homeostasis GO:0055082 215 0.289
regulation of intracellular transport GO:0032386 159 0.289
cytokine production GO:0001816 319 0.287
nitrogen compound transport GO:0071705 271 0.286
blastoderm segmentation GO:0007350 13 0.285
positive regulation of protein phosphorylation GO:0001934 242 0.283
regulation of blood circulation GO:1903522 93 0.280
regulation of cellular component size GO:0032535 121 0.279
Mouse
t cell activation GO:0042110 289 0.278
regulation of cell substrate adhesion GO:0010810 73 0.265
preganglionic parasympathetic nervous system development GO:0021783 17 0.265
Mouse
endothelial cell migration GO:0043542 44 0.263
Mouse
axonal fasciculation GO:0007413 15 0.263
regulation of map kinase activity GO:0043405 120 0.259
cellular homeostasis GO:0019725 240 0.255
regulation of protein serine threonine kinase activity GO:0071900 157 0.255
positive regulation of cell projection organization GO:0031346 95 0.253
Mouse
response to radiation GO:0009314 165 0.251
regulation of anatomical structure size GO:0090066 178 0.250
Mouse
synapse assembly GO:0007416 56 0.248
Mouse
regulation of interleukin 10 secretion GO:2001179 4 0.241
glycosylation GO:0070085 62 0.239
microtubule based process GO:0007017 236 0.238
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.238
glycoprotein metabolic process GO:0009100 116 0.237
extrinsic apoptotic signaling pathway GO:0097191 126 0.235
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.232
substrate dependent cerebral cortex tangential migration GO:0021825 3 0.232
tissue migration GO:0090130 68 0.228
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.226
peptidyl tyrosine phosphorylation GO:0018108 143 0.225
detection of stimulus GO:0051606 84 0.223
neural tube formation GO:0001841 108 0.223
Mouse
cell maturation GO:0048469 127 0.220
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.219
neural crest cell migration involved in sympathetic nervous system development GO:1903045 1 0.218
detection of abiotic stimulus GO:0009582 60 0.218
regulation of secretion by cell GO:1903530 249 0.216
positive regulation of nervous system development GO:0051962 221 0.215
Mouse
regulation of vasculature development GO:1901342 88 0.215
Mouse
cation transport GO:0006812 399 0.215
positive regulation of mapk cascade GO:0043410 170 0.213
skin development GO:0043588 220 0.210
oogenesis GO:0048477 56 0.210
cellular response to growth factor stimulus GO:0071363 197 0.206
axon guidance GO:0007411 141 0.205
Mouse Fly
regulation of secretion GO:0051046 274 0.205
negative regulation of protein phosphorylation GO:0001933 126 0.203
regulation of protein localization GO:0032880 231 0.203
embryonic organ morphogenesis GO:0048562 276 0.203
morphogenesis of a branching structure GO:0001763 203 0.198
central nervous system neuron development GO:0021954 67 0.197
Mouse
alpha beta t cell differentiation GO:0046632 69 0.195
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.195
regulation of cellular amino acid metabolic process GO:0006521 5 0.194
male gamete generation GO:0048232 285 0.194
regulation of ras protein signal transduction GO:0046578 114 0.193
Mouse
commissural neuron axon guidance GO:0071679 8 0.191
modification dependent macromolecule catabolic process GO:0043632 133 0.190
microtubule cytoskeleton organization GO:0000226 157 0.190
protein localization to endosome GO:0036010 2 0.189
sympathetic nervous system development GO:0048485 22 0.188
Mouse
protein localization to plasma membrane GO:0072659 57 0.186
peptide transport GO:0015833 133 0.186
negative regulation of behavior GO:0048521 14 0.185
Mouse
protein targeting GO:0006605 143 0.184
regulation of body fluid levels GO:0050878 162 0.183
macromolecule catabolic process GO:0009057 281 0.181
cellular metal ion homeostasis GO:0006875 151 0.181
stem cell development GO:0048864 219 0.180
cellular protein catabolic process GO:0044257 155 0.179
hypothalamus cell migration GO:0021855 5 0.179
sensory perception of chemical stimulus GO:0007606 51 0.178
detection of visible light GO:0009584 14 0.177
negative regulation of synapse assembly GO:0051964 3 0.177
positive regulation of gene silencing by mirna GO:2000637 1 0.177
negative regulation of protein modification process GO:0031400 163 0.177
regulation of neuron death GO:1901214 134 0.176
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.174
ribose phosphate biosynthetic process GO:0046390 59 0.174
protein localization to membrane GO:0072657 108 0.173
actin cytoskeleton organization GO:0030036 220 0.173
negative regulation of cell growth GO:0030308 44 0.173
Mouse
epithelium migration GO:0090132 63 0.173
Mouse
protein localization to organelle GO:0033365 185 0.173
acetylcholine transport GO:0015870 2 0.171
peptidyl tyrosine modification GO:0018212 145 0.170
tissue remodeling GO:0048771 102 0.169
negative regulation of phosphate metabolic process GO:0045936 184 0.169
hypothalamus cell differentiation GO:0021979 8 0.168
dichotomous subdivision of an epithelial terminal unit GO:0060600 11 0.166
positive regulation of proteolysis GO:0045862 85 0.166
regulation of proteolysis GO:0030162 164 0.163
parasympathetic nervous system development GO:0048486 19 0.162
Mouse
macromolecule glycosylation GO:0043413 55 0.161
cellular amine metabolic process GO:0044106 44 0.160
proteasomal protein catabolic process GO:0010498 98 0.160
hormone secretion GO:0046879 128 0.160
endomembrane system organization GO:0010256 147 0.160
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.159
regulation of insulin receptor signaling pathway GO:0046626 21 0.159
positive regulation of nucleoside metabolic process GO:0045979 91 0.158
Mouse
negative regulation of axon extension GO:0030517 19 0.156
Mouse
nerve development GO:0021675 67 0.156
Mouse
acid secretion GO:0046717 33 0.156
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.155
regulation of cysteine type endopeptidase activity GO:2000116 65 0.155
metal ion homeostasis GO:0055065 189 0.153
regulation of response to wounding GO:1903034 189 0.152
cell type specific apoptotic process GO:0097285 268 0.151
lipid transport GO:0006869 98 0.150
regulation of protein binding GO:0043393 60 0.149
Mouse
establishment of protein localization to membrane GO:0090150 54 0.149
dna metabolic process GO:0006259 303 0.149
lipid localization GO:0010876 126 0.149
response to organonitrogen compound GO:0010243 246 0.148
muscle cell differentiation GO:0042692 261 0.148
regulation of endopeptidase activity GO:0052548 89 0.148
positive regulation of protein kinase activity GO:0045860 144 0.147
negative regulation of cell proliferation GO:0008285 296 0.147
Mouse
smooth muscle cell migration GO:0014909 10 0.144
cell junction organization GO:0034330 77 0.143
positive regulation of lymphocyte activation GO:0051251 140 0.141
regulation of ion transport GO:0043269 215 0.140
negative regulation of neuron apoptotic process GO:0043524 92 0.140
sensory perception GO:0007600 245 0.139
telencephalon development GO:0021537 186 0.138
Mouse
protein catabolic process GO:0030163 221 0.138
substrate dependent cell migration GO:0006929 18 0.137
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.137
Mouse
regulation of protein autophosphorylation GO:0031952 8 0.137
regulation of kinase activity GO:0043549 249 0.137
response to growth factor GO:0070848 198 0.135
lactation GO:0007595 25 0.135
leukocyte differentiation GO:0002521 342 0.134
tube closure GO:0060606 91 0.133
Mouse
innervation GO:0060384 22 0.133
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.133
peptide secretion GO:0002790 114 0.129
negative regulation of nervous system development GO:0051961 156 0.129
Mouse
axonogenesis involved in innervation GO:0060385 5 0.129
regulation of system process GO:0044057 200 0.128
detection of stimulus involved in sensory perception GO:0050906 44 0.128
generation of precursor metabolites and energy GO:0006091 103 0.128
cytoplasmic transport GO:0016482 234 0.128
platelet activation GO:0030168 40 0.127
cell junction assembly GO:0034329 52 0.127
appendage development GO:0048736 166 0.126
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.123
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.123
regulation of intracellular protein transport GO:0033157 82 0.123
neuron apoptotic process GO:0051402 142 0.123
regulation of reproductive process GO:2000241 66 0.122
regulation of cell activation GO:0050865 289 0.121
coagulation GO:0050817 78 0.119
ganglion development GO:0061548 13 0.118
epithelial tube morphogenesis GO:0060562 303 0.118
Mouse
negative regulation of cellular component organization GO:0051129 194 0.115
Mouse
erk1 and erk2 cascade GO:0070371 77 0.115
positive regulation of t cell activation GO:0050870 101 0.115
ubiquitin dependent protein catabolic process GO:0006511 129 0.114
regulation of erk1 and erk2 cascade GO:0070372 71 0.114
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.114
regulation of neuron migration GO:2001222 22 0.113
Mouse
syncytiotrophoblast cell differentiation involved in labyrinthine layer development GO:0060715 2 0.113
regulation of transferase activity GO:0051338 263 0.113
gene silencing by mirna GO:0035195 10 0.112
actin filament organization GO:0007015 113 0.112
acetate ester transport GO:1901374 2 0.112
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.111
Mouse
alpha beta t cell activation GO:0046631 91 0.110
gland development GO:0048732 330 0.109
regulation of actin cytoskeleton organization GO:0032956 84 0.108
response to fibroblast growth factor GO:0071774 47 0.107
regulation of protein catabolic process GO:0042176 108 0.107
hindbrain development GO:0030902 128 0.106
Mouse
skeletal system development GO:0001501 356 0.105
Mouse
amide transport GO:0042886 138 0.105
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.105
regulation of neuron apoptotic process GO:0043523 122 0.105
vegf activated neuropilin signaling pathway GO:0038190 2 0.104
monosaccharide metabolic process GO:0005996 106 0.104
positive regulation of secretion GO:0051047 130 0.104
activation of adenylate cyclase activity GO:0007190 4 0.103
negative regulation of cell motility GO:2000146 61 0.103
maternal determination of anterior posterior axis embryo GO:0008358 2 0.103
positive regulation of secretion by cell GO:1903532 114 0.103
regulation of vesicle mediated transport GO:0060627 139 0.102
regulation of peptide hormone secretion GO:0090276 75 0.102
cell recognition GO:0008037 83 0.102
Fly
regulation of cell shape GO:0008360 39 0.101
Mouse
establishment of protein localization to organelle GO:0072594 118 0.101
synaptic vesicle transport GO:0048489 57 0.101
regulation of stress activated mapk cascade GO:0032872 69 0.100
cell substrate adhesion GO:0031589 130 0.100
glucose homeostasis GO:0042593 128 0.100
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.100
morphogenesis of a branching epithelium GO:0061138 193 0.099
forebrain neuron development GO:0021884 30 0.099
Mouse
apoptotic signaling pathway GO:0097190 306 0.099
regulation of jnk cascade GO:0046328 62 0.098
rhythmic process GO:0048511 174 0.098
germ cell development GO:0007281 185 0.098
respiratory system development GO:0060541 190 0.097
ossification GO:0001503 216 0.097
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.097
positive regulation of kinase activity GO:0033674 155 0.097
negative regulation of hydrolase activity GO:0051346 71 0.097
regulation of catenin import into nucleus GO:0035412 5 0.096
ameboidal type cell migration GO:0001667 128 0.096
Mouse
positive regulation of necrotic cell death GO:0010940 1 0.096
endocytosis GO:0006897 168 0.095
protein modification by small protein conjugation GO:0032446 187 0.095
limbic system development GO:0021761 72 0.095
Mouse
regulation of cellular response to stress GO:0080135 159 0.095
neuron death GO:0070997 154 0.095
regulation of tight junction assembly GO:2000810 2 0.094
detection of light stimulus GO:0009583 25 0.094
cellular divalent inorganic cation homeostasis GO:0072503 127 0.093
limb development GO:0060173 166 0.093
Mouse
regulation of hormone secretion GO:0046883 88 0.093
cyclic purine nucleotide metabolic process GO:0052652 43 0.092
ovarian follicle development GO:0001541 40 0.092
regulation of establishment of protein localization GO:0070201 181 0.092
carboxylic acid transport GO:0046942 100 0.092
regulation of leukocyte proliferation GO:0070663 121 0.091
rap protein signal transduction GO:0032486 3 0.091
positive regulation of smooth muscle cell migration GO:0014911 4 0.091
negative regulation of catenin import into nucleus GO:0035414 2 0.090
regulation of angiogenesis GO:0045765 81 0.090
Mouse
regulation of binding GO:0051098 111 0.090
Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.090
protein glycosylation GO:0006486 55 0.090
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.090
salivary gland development GO:0007431 37 0.089
positive regulation of synapse assembly GO:0051965 18 0.089
positive regulation of axon extension GO:0045773 20 0.089
sympathetic ganglion development GO:0061549 9 0.088
actin filament bundle assembly GO:0051017 40 0.087
blood coagulation GO:0007596 76 0.087
embryonic epithelial tube formation GO:0001838 130 0.087
Mouse
jnk cascade GO:0007254 72 0.087
regulation of ossification GO:0030278 112 0.087
myeloid cell differentiation GO:0030099 233 0.087
reactive oxygen species biosynthetic process GO:1903409 8 0.087
protein kinase b signaling GO:0043491 74 0.087
central nervous system neuron differentiation GO:0021953 162 0.086
Mouse
rhodopsin mediated signaling pathway GO:0016056 4 0.086
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.085
cellular ion homeostasis GO:0006873 165 0.085
mammary gland morphogenesis GO:0060443 54 0.085
establishment of synaptic vesicle localization GO:0097480 57 0.085
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.085
cation homeostasis GO:0055080 212 0.084
visual perception GO:0007601 52 0.084
segmentation GO:0035282 93 0.084
Mouse
positive regulation of cell activation GO:0050867 158 0.083
molting cycle GO:0042303 90 0.083
regulation of heart contraction GO:0008016 77 0.083
retina development in camera type eye GO:0060041 119 0.083
oxidation reduction process GO:0055114 342 0.082
nuclear transport GO:0051169 139 0.082
calcium ion homeostasis GO:0055074 127 0.082
blood circulation GO:0008015 195 0.081
stem cell proliferation GO:0072089 117 0.081
Mouse
modification dependent protein catabolic process GO:0019941 133 0.081
mitotic cell cycle GO:0000278 195 0.080
negative regulation of phosphorus metabolic process GO:0010563 184 0.080
sensory perception of sound GO:0007605 97 0.080
nuclear import GO:0051170 95 0.080
positive regulation of map kinase activity GO:0043406 84 0.080
positive regulation of apoptotic process GO:0043065 217 0.080
synaptic transmission GO:0007268 329 0.079
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.078
leukocyte activation involved in immune response GO:0002366 126 0.078
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.078
monocarboxylic acid transport GO:0015718 44 0.077
heart contraction GO:0060047 93 0.077
heart morphogenesis GO:0003007 178 0.077
Mouse
ear morphogenesis GO:0042471 118 0.077
cellular protein complex assembly GO:0043623 116 0.076
cerebral cortex cell migration GO:0021795 44 0.076
regulation of cellular component biogenesis GO:0044087 181 0.075
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.075
cranial nerve structural organization GO:0021604 13 0.075
Mouse
regeneration GO:0031099 38 0.075
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.075
regulation of ral gtpase activity GO:0032315 4 0.074
cyclic nucleotide biosynthetic process GO:0009190 44 0.074
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.074
peptide hormone secretion GO:0030072 109 0.074
response to peptide hormone GO:0043434 127 0.074
camera type eye development GO:0043010 266 0.073
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.073
negative regulation of neuron death GO:1901215 98 0.072
cell cell junction organization GO:0045216 72 0.072
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.071
hair follicle development GO:0001942 85 0.070
regulation of endothelial cell migration GO:0010594 22 0.070
myotube differentiation GO:0014902 105 0.070
cerebellum vasculature development GO:0061300 1 0.070
positive regulation of protein autophosphorylation GO:0031954 4 0.070
negative regulation of intracellular signal transduction GO:1902532 167 0.070
organic acid transport GO:0015849 101 0.069
regulation of peptidase activity GO:0052547 96 0.069
negative regulation of dendritic spine morphogenesis GO:0061002 3 0.069
mesodermal cell migration GO:0008078 4 0.069
gonad development GO:0008406 141 0.068
nucleotide biosynthetic process GO:0009165 78 0.068
regulation of cell cell adhesion mediated by cadherin GO:2000047 2 0.068
muscle contraction GO:0006936 101 0.068
insulin secretion GO:0030073 89 0.068
fasciculation of sensory neuron axon GO:0097155 3 0.068
purine ribonucleotide biosynthetic process GO:0009152 59 0.068
stress activated mapk cascade GO:0051403 80 0.068
carbohydrate homeostasis GO:0033500 128 0.068
regulation of smooth muscle cell migration GO:0014910 6 0.067
plasma membrane organization GO:0007009 90 0.067
acetylcholine secretion neurotransmission GO:0014055 2 0.067
regulation of multi organism process GO:0043900 111 0.067
positive regulation of cell adhesion GO:0045785 80 0.067
transmission of nerve impulse GO:0019226 76 0.067
stress activated protein kinase signaling cascade GO:0031098 81 0.067
establishment or maintenance of cell polarity GO:0007163 86 0.066
establishment of vesicle localization GO:0051650 81 0.066
calcium ion dependent exocytosis GO:0017156 35 0.066
fat cell differentiation GO:0045444 160 0.066
negative regulation of cellular protein metabolic process GO:0032269 247 0.066
bone mineralization GO:0030282 54 0.066
sialylation GO:0097503 14 0.066

Plxna1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.170