Mus musculus

122 known processes

Acadm

acyl-Coenzyme A dehydrogenase, medium chain

(Aliases: AU018656,MCAD)

Acadm biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
fatty acid oxidation GO:0019395 28 1.000
lipid oxidation GO:0034440 29 0.999
monocarboxylic acid catabolic process GO:0072329 27 0.998
cellular lipid catabolic process GO:0044242 52 0.997
fatty acid beta oxidation GO:0006635 16 0.995
small molecule catabolic process GO:0044282 71 0.988
fatty acid metabolic process GO:0006631 121 0.985
lipid modification GO:0030258 65 0.975
fatty acid catabolic process GO:0009062 25 0.970
lipid catabolic process GO:0016042 69 0.957
carboxylic acid catabolic process GO:0046395 51 0.954
monocarboxylic acid metabolic process GO:0032787 191 0.934
organic acid catabolic process GO:0016054 51 0.907
very long chain fatty acid metabolic process GO:0000038 8 0.892
thioester metabolic process GO:0035383 19 0.887
coenzyme metabolic process GO:0006732 52 0.879
cellular lipid metabolic process GO:0044255 323 0.878
oxidation reduction process GO:0055114 342 0.834
very long chain fatty acid catabolic process GO:0042760 2 0.825
peroxisome organization GO:0007031 7 0.730
fatty acid alpha oxidation GO:0001561 2 0.684
establishment of protein localization to peroxisome GO:0072663 4 0.619
protein localization to peroxisome GO:0072662 4 0.365
protein targeting to peroxisome GO:0006625 4 0.335
cellular amino acid metabolic process GO:0006520 103 0.316
cellular ketone metabolic process GO:0042180 84 0.308
small molecule biosynthetic process GO:0044283 132 0.262
Human
peroxisomal transport GO:0043574 4 0.253
acyl coa metabolic process GO:0006637 19 0.248
coenzyme biosynthetic process GO:0009108 23 0.241
protein import into peroxisome matrix GO:0016558 3 0.227
sulfur compound metabolic process GO:0006790 100 0.203
lipid biosynthetic process GO:0008610 179 0.201
fatty acid transmembrane transport GO:1902001 1 0.200
cofactor metabolic process GO:0051186 80 0.180
organic hydroxy compound metabolic process GO:1901615 203 0.171
branched chain amino acid catabolic process GO:0009083 2 0.146
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 11 0.138
amine metabolic process GO:0009308 45 0.136
lipid localization GO:0010876 126 0.129
Worm
cellular amine metabolic process GO:0044106 44 0.123
cellular amino acid catabolic process GO:0009063 25 0.123
nucleobase containing small molecule metabolic process GO:0055086 352 0.112
anion transport GO:0006820 177 0.111
nucleoside phosphate metabolic process GO:0006753 338 0.102
progesterone biosynthetic process GO:0006701 1 0.094
generation of precursor metabolites and energy GO:0006091 103 0.094
pyruvate transport GO:0006848 2 0.093
glycerolipid metabolic process GO:0046486 122 0.083
cholesterol transport GO:0030301 38 0.081
fatty acyl coa metabolic process GO:0035337 4 0.081
acetyl coa biosynthetic process GO:0006085 5 0.076
protein oligomerization GO:0051259 67 0.073
Rat
regulation of cellular ketone metabolic process GO:0010565 66 0.068
nucleotide metabolic process GO:0009117 332 0.068
glycerol ether metabolic process GO:0006662 2 0.067
organic anion transport GO:0015711 137 0.067
isoprenoid metabolic process GO:0006720 29 0.060
ether lipid metabolic process GO:0046485 2 0.060
steroid metabolic process GO:0008202 119 0.058
pyrimidine containing compound catabolic process GO:0072529 3 0.056
regulation of hormone levels GO:0010817 211 0.053
regulation of fatty acid metabolic process GO:0019217 28 0.053
regulation of lipid metabolic process GO:0019216 118 0.052
glycerolipid biosynthetic process GO:0045017 50 0.052
progesterone metabolic process GO:0042448 4 0.052
succinyl coa metabolic process GO:0006104 1 0.049
acylglycerol metabolic process GO:0006639 55 0.049
glycosyl compound metabolic process GO:1901657 246 0.047
ossification GO:0001503 216 0.047
organonitrogen compound biosynthetic process GO:1901566 192 0.047
response to oxidative stress GO:0006979 123 0.047
glutamine family amino acid biosynthetic process GO:0009084 2 0.046
phospholipid metabolic process GO:0006644 87 0.045
maintenance of location GO:0051235 89 0.043
Worm
acetyl coa biosynthetic process from pyruvate GO:0006086 3 0.042
lipid storage GO:0019915 36 0.042
Worm
ribonucleoside triphosphate metabolic process GO:0009199 220 0.041
response to organonitrogen compound GO:0010243 246 0.041
hormone metabolic process GO:0042445 86 0.041
protein homooligomerization GO:0051260 43 0.041
Rat
lipid transport GO:0006869 98 0.039
cellular response to hormone stimulus GO:0032870 150 0.039
organonitrogen compound catabolic process GO:1901565 264 0.038
regulation of mitochondrion organization GO:0010821 27 0.036
sterol transport GO:0015918 38 0.036
sterol metabolic process GO:0016125 58 0.036
negative regulation of fatty acid metabolic process GO:0045922 10 0.035
purine nucleoside monophosphate metabolic process GO:0009126 81 0.035
alcohol metabolic process GO:0006066 116 0.035
mitochondrial transport GO:0006839 36 0.034
organic hydroxy compound biosynthetic process GO:1901617 77 0.034
Human
c21 steroid hormone biosynthetic process GO:0006700 3 0.033
atp metabolic process GO:0046034 75 0.033
organic cyclic compound catabolic process GO:1901361 295 0.033
organophosphate biosynthetic process GO:0090407 122 0.033
alpha amino acid catabolic process GO:1901606 18 0.033
regulation of cellular amino acid metabolic process GO:0006521 5 0.032
nucleoside monophosphate metabolic process GO:0009123 85 0.032
regulation of steroid metabolic process GO:0019218 39 0.031
glycerophospholipid metabolic process GO:0006650 71 0.031
retinoid metabolic process GO:0001523 24 0.031
ribonucleotide metabolic process GO:0009259 291 0.030
purine nucleoside metabolic process GO:0042278 241 0.029
gonad development GO:0008406 141 0.029
amino acid betaine metabolic process GO:0006577 7 0.029
transmembrane transport GO:0055085 412 0.029
alpha amino acid metabolic process GO:1901605 59 0.029
cellular modified amino acid metabolic process GO:0006575 63 0.029
microtubule based process GO:0007017 236 0.029
regulation of fatty acid oxidation GO:0046320 10 0.028
long chain fatty acid import GO:0044539 2 0.028
cellular macromolecule catabolic process GO:0044265 206 0.028
regulation of fatty acid beta oxidation GO:0031998 1 0.027
forebrain development GO:0030900 302 0.027
defense response to bacterium GO:0042742 119 0.027
protein targeting GO:0006605 143 0.026
alcohol biosynthetic process GO:0046165 43 0.026
organic acid transport GO:0015849 101 0.026
protein localization to organelle GO:0033365 185 0.026
hepaticobiliary system development GO:0061008 67 0.026
telencephalon development GO:0021537 186 0.026
acetyl coa metabolic process GO:0006084 8 0.025
apoptotic mitochondrial changes GO:0008637 48 0.025
epithelial cell development GO:0002064 159 0.025
regulation of cell cycle GO:0051726 281 0.025
microtubule cytoskeleton organization GO:0000226 157 0.025
ribose phosphate metabolic process GO:0019693 291 0.025
purine ribonucleoside metabolic process GO:0046128 241 0.025
defense response to other organism GO:0098542 197 0.024
response to oxygen levels GO:0070482 62 0.024
germ cell development GO:0007281 185 0.023
monocarboxylic acid transport GO:0015718 44 0.023
cell type specific apoptotic process GO:0097285 268 0.023
nad metabolic process GO:0019674 7 0.023
cellular biogenic amine metabolic process GO:0006576 28 0.023
macromolecule catabolic process GO:0009057 281 0.023
fat cell differentiation GO:0045444 160 0.023
dna metabolic process GO:0006259 303 0.022
negative regulation of cell proliferation GO:0008285 296 0.022
regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 14 0.022
positive regulation of protein modification process GO:0031401 299 0.022
nucleoside metabolic process GO:0009116 246 0.022
cellular nitrogen compound catabolic process GO:0044270 280 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
endocytosis GO:0006897 168 0.022
regulation of cellular catabolic process GO:0031329 242 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
response to peptide GO:1901652 136 0.021
negative regulation of cellular component organization GO:0051129 194 0.021
bone development GO:0060348 120 0.021
diterpenoid metabolic process GO:0016101 24 0.021
ketone biosynthetic process GO:0042181 8 0.021
cholesterol metabolic process GO:0008203 56 0.021
regulation of mitochondrial fission GO:0090140 3 0.021
positive regulation of mitochondrial membrane permeability GO:0035794 12 0.020
establishment of protein localization to organelle GO:0072594 118 0.020
skeletal system morphogenesis GO:0048705 203 0.020
carboxylic acid transport GO:0046942 100 0.020
pyrimidine nucleobase metabolic process GO:0006206 3 0.020
response to organic cyclic compound GO:0014070 198 0.020
Rat
acyl coa biosynthetic process GO:0071616 7 0.020
positive regulation of lipid metabolic process GO:0045834 40 0.020
protein localization to membrane GO:0072657 108 0.020
regulation of cellular amine metabolic process GO:0033238 20 0.019
innate immune response GO:0045087 157 0.019
adiponectin activated signaling pathway GO:0033211 4 0.019
neuron apoptotic process GO:0051402 142 0.019
mitochondrial membrane organization GO:0007006 26 0.019
protein processing GO:0016485 163 0.019
substantia nigra development GO:0021762 2 0.019
homeostasis of number of cells GO:0048872 210 0.019
response to peptide hormone GO:0043434 127 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
regulation of membrane permeability GO:0090559 18 0.019
positive regulation of steroid biosynthetic process GO:0010893 4 0.018
negative regulation of phosphorus metabolic process GO:0010563 184 0.018
cholesterol homeostasis GO:0042632 44 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
regulation of organelle organization GO:0033043 289 0.018
leukocyte differentiation GO:0002521 342 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.018
regulation of secretion by cell GO:1903530 249 0.018
glutamate biosynthetic process GO:0006537 2 0.017
positive regulation of organelle organization GO:0010638 128 0.017
positive regulation of glycolytic process GO:0045821 4 0.017
organic acid biosynthetic process GO:0016053 86 0.017
Human
negative regulation of immune system process GO:0002683 209 0.017
ether metabolic process GO:0018904 2 0.017
response to drug GO:0042493 75 0.017
Rat
membrane organization GO:0061024 245 0.017
negative regulation of apoptotic signaling pathway GO:2001234 104 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
peptidyl amino acid modification GO:0018193 336 0.016
neuron migration GO:0001764 122 0.016
intracellular protein transport GO:0006886 204 0.016
male gamete generation GO:0048232 285 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
regulation of cell cycle process GO:0010564 160 0.016
intracellular cholesterol transport GO:0032367 3 0.016
spermatogenesis GO:0007283 284 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
glycerophospholipid biosynthetic process GO:0046474 32 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
monocarboxylic acid biosynthetic process GO:0072330 61 0.016
Human
development of primary male sexual characteristics GO:0046546 88 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.016
carboxylic acid biosynthetic process GO:0046394 86 0.016
Human
negative regulation of mitochondrion organization GO:0010823 9 0.015
apoptotic signaling pathway GO:0097190 306 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
fatty acid biosynthetic process GO:0006633 41 0.015
positive regulation of cell activation GO:0050867 158 0.015
response to hypoxia GO:0001666 58 0.015
neuron death GO:0070997 154 0.015
nephron development GO:0072006 109 0.015
cofactor biosynthetic process GO:0051188 41 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
gland development GO:0048732 330 0.015
regulation of mitochondrial membrane permeability GO:0046902 17 0.015
neutral lipid metabolic process GO:0006638 57 0.015
myeloid cell differentiation GO:0030099 233 0.015
negative regulation of fatty acid oxidation GO:0046322 5 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.014
mitochondrial outer membrane permeabilization involved in programmed cell death GO:1902686 11 0.014
mitochondrion organization GO:0007005 134 0.014
developmental maturation GO:0021700 193 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
sensory perception GO:0007600 245 0.014
ion transmembrane transport GO:0034220 361 0.014
response to testosterone GO:0033574 3 0.014
negative regulation of protein metabolic process GO:0051248 282 0.014
regulation of transferase activity GO:0051338 263 0.014
male sex differentiation GO:0046661 109 0.014
anion transmembrane transport GO:0098656 71 0.014
cytokine production GO:0001816 319 0.013
regulation of fat cell differentiation GO:0045598 81 0.013
lipid homeostasis GO:0055088 63 0.013
rna processing GO:0006396 105 0.013
sertoli cell differentiation GO:0060008 18 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
cellular response to oxygen levels GO:0071453 20 0.013
action potential GO:0001508 78 0.013
regulation of membrane potential GO:0042391 192 0.013
aromatic compound catabolic process GO:0019439 286 0.013
pteridine containing compound metabolic process GO:0042558 5 0.013
mapk cascade GO:0000165 281 0.013
regulation of mapk cascade GO:0043408 248 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
sulfur compound biosynthetic process GO:0044272 37 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
regulation of kinase activity GO:0043549 249 0.012
nitrogen compound transport GO:0071705 271 0.012
negative regulation of organelle organization GO:0010639 90 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
response to steroid hormone GO:0048545 56 0.012
Rat
phospholipid transport GO:0015914 21 0.012
regulation of lipid biosynthetic process GO:0046890 54 0.012
protein import GO:0017038 101 0.012
terpenoid metabolic process GO:0006721 25 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
mitochondrion transport along microtubule GO:0047497 3 0.012
regulation of ossification GO:0030278 112 0.012
renal system development GO:0072001 225 0.012
steroid biosynthetic process GO:0006694 47 0.012
heterocycle catabolic process GO:0046700 280 0.012
tissue homeostasis GO:0001894 115 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
sulfur amino acid metabolic process GO:0000096 9 0.012
organelle fission GO:0048285 170 0.012
positive regulation of cell death GO:0010942 224 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
multicellular organismal signaling GO:0035637 91 0.012
pyrimidine containing compound metabolic process GO:0072527 11 0.012
response to acid chemical GO:0001101 111 0.012
cellular protein catabolic process GO:0044257 155 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
response to insulin GO:0032868 100 0.012
organic hydroxy compound transport GO:0015850 93 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
purine containing compound catabolic process GO:0072523 213 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
regulation of steroid biosynthetic process GO:0050810 26 0.011
regulation of secretion GO:0051046 274 0.011
regulation of homeostatic process GO:0032844 182 0.011
phosphatidylcholine metabolic process GO:0046470 13 0.011
positive regulation of cholesterol homeostasis GO:2000189 2 0.011
purine nucleotide metabolic process GO:0006163 302 0.011
epithelial cell proliferation GO:0050673 174 0.011
ensheathment of neurons GO:0007272 76 0.011
cellular respiration GO:0045333 38 0.011
regulation of removal of superoxide radicals GO:2000121 4 0.011
sertoli cell development GO:0060009 15 0.011
response to catecholamine GO:0071869 4 0.011
transmission of nerve impulse GO:0019226 76 0.011
organophosphate catabolic process GO:0046434 232 0.011
myeloid leukocyte differentiation GO:0002573 119 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
tricarboxylic acid metabolic process GO:0072350 5 0.010
urogenital system development GO:0001655 261 0.010
regulation of cholesterol metabolic process GO:0090181 14 0.010
triglyceride metabolic process GO:0006641 51 0.010
nadh metabolic process GO:0006734 1 0.010
epithelial cell morphogenesis GO:0003382 41 0.010
inorganic cation transmembrane transport GO:0098662 207 0.010
development of primary sexual characteristics GO:0045137 143 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
nuclear transport GO:0051169 139 0.010
female gamete generation GO:0007292 74 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.010
carbohydrate derivative biosynthetic process GO:1901137 183 0.010
datp metabolic process GO:0046060 2 0.010
locomotory behavior GO:0007626 195 0.010

Acadm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.766
inherited metabolic disorder DOID:655 0 0.595
amino acid metabolic disorder DOID:9252 0 0.231
lipid metabolism disorder DOID:3146 0 0.140
hyperinsulinemic hypoglycemia DOID:13317 0 0.070
carbohydrate metabolic disorder DOID:2978 0 0.070
disease of cellular proliferation DOID:14566 0 0.026
organic acidemia DOID:0060159 0 0.020
cancer DOID:162 0 0.014
retinal disease DOID:5679 0 0.013
retinal degeneration DOID:8466 0 0.013
sensory system disease DOID:0050155 0 0.013
disease of anatomical entity DOID:7 0 0.013
retinitis pigmentosa DOID:10584 0 0.013
eye and adnexa disease DOID:1492 0 0.013
nervous system disease DOID:863 0 0.013
eye disease DOID:5614 0 0.013