Mus musculus

188 known processes

Trib3

tribbles homolog 3 (Drosophila)

(Aliases: Nipk,Ifld2,TRB-3,Trb3,SKIP3,SINK)

Trib3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.771
response to endoplasmic reticulum stress GO:0034976 53 0.711
Human
circadian regulation of gene expression GO:0032922 48 0.659
apoptotic signaling pathway GO:0097190 306 0.645
Human
negative regulation of response to oxidative stress GO:1902883 10 0.581
olfactory bulb interneuron development GO:0021891 7 0.482
carbohydrate metabolic process GO:0005975 230 0.467
Mouse
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 8 0.455
forebrain development GO:0030900 302 0.451
regulation of response to oxidative stress GO:1902882 19 0.432
intrinsic apoptotic signaling pathway GO:0097193 132 0.403
Human
positive regulation of neuron apoptotic process GO:0043525 25 0.396
monosaccharide metabolic process GO:0005996 106 0.390
hexose metabolic process GO:0019318 98 0.365
regulation of dna templated transcription in response to stress GO:0043620 9 0.333
positive regulation of cell death GO:0010942 224 0.318
hexose biosynthetic process GO:0019319 39 0.309
glucose metabolic process GO:0006006 92 0.309
multicellular organism growth GO:0035264 161 0.291
Mouse
regulation of cellular response to oxidative stress GO:1900407 19 0.287
positive regulation of apoptotic process GO:0043065 217 0.286
gluconeogenesis GO:0006094 39 0.283
positive regulation of programmed cell death GO:0043068 218 0.271
negative regulation of oxidative stress induced cell death GO:1903202 9 0.265
negative regulation of cellular response to oxidative stress GO:1900408 10 0.255
central nervous system neuron differentiation GO:0021953 162 0.240
carbohydrate biosynthetic process GO:0016051 74 0.219
forebrain neuron differentiation GO:0021879 52 0.215
cellular response to oxidative stress GO:0034599 76 0.212
cellular amino acid metabolic process GO:0006520 103 0.195
olfactory lobe development GO:0021988 32 0.194
telencephalon development GO:0021537 186 0.193
central nervous system neuron development GO:0021954 67 0.189
forebrain neuron development GO:0021884 30 0.187
cell type specific apoptotic process GO:0097285 268 0.186
olfactory bulb interneuron differentiation GO:0021889 12 0.173
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 2 0.166
response to organonitrogen compound GO:0010243 246 0.165
forebrain generation of neurons GO:0021872 63 0.161
regulation of cellular response to stress GO:0080135 159 0.158
regulation of neuron apoptotic process GO:0043523 122 0.138
negative regulation of neuron death GO:1901215 98 0.133
negative regulation of cellular protein metabolic process GO:0032269 247 0.131
negative regulation of molecular function GO:0044092 258 0.126
monosaccharide biosynthetic process GO:0046364 44 0.123
neuron apoptotic process GO:0051402 142 0.123
cytokine production GO:0001816 319 0.112
negative regulation of protein metabolic process GO:0051248 282 0.110
positive regulation of protein modification process GO:0031401 299 0.107
positive regulation of neuron death GO:1901216 28 0.106
innate immune response GO:0045087 157 0.102
neuron death GO:0070997 154 0.101
rhythmic process GO:0048511 174 0.099
cation transport GO:0006812 399 0.097
macromolecule catabolic process GO:0009057 281 0.096
Mouse Fly
regulation of cell cycle GO:0051726 281 0.096
Fly
response to peptide GO:1901652 136 0.095
mitochondrion organization GO:0007005 134 0.093
regulation of oxidative stress induced cell death GO:1903201 14 0.089
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.089
oxidation reduction process GO:0055114 342 0.084
Mouse
response to insulin GO:0032868 100 0.080
protein ubiquitination GO:0016567 171 0.077
regulation of cytokine production GO:0001817 266 0.077
regulation of defense response GO:0031347 233 0.076
camera type eye development GO:0043010 266 0.070
regulation of cellular ketone metabolic process GO:0010565 66 0.066
translation GO:0006412 93 0.065
monocarboxylic acid metabolic process GO:0032787 191 0.063
g protein coupled receptor signaling pathway GO:0007186 243 0.063
cellular lipid metabolic process GO:0044255 323 0.063
anion transport GO:0006820 177 0.063
cellular amine metabolic process GO:0044106 44 0.062
response to radiation GO:0009314 165 0.060
regulation of proteolysis GO:0030162 164 0.059
Mouse Fly
nitrogen compound transport GO:0071705 271 0.059
modification dependent macromolecule catabolic process GO:0043632 133 0.058
Mouse Fly
cellular response to hormone stimulus GO:0032870 150 0.056
cellular response to insulin stimulus GO:0032869 78 0.055
multicellular organismal homeostasis GO:0048871 164 0.054
organic hydroxy compound metabolic process GO:1901615 203 0.053
t cell activation GO:0042110 289 0.053
small molecule biosynthetic process GO:0044283 132 0.053
mitotic cell cycle GO:0000278 195 0.052
Fly
cellular ketone metabolic process GO:0042180 84 0.052
lipid biosynthetic process GO:0008610 179 0.052
reactive oxygen species metabolic process GO:0072593 84 0.051
organophosphate biosynthetic process GO:0090407 122 0.050
regulation of cellular amino acid metabolic process GO:0006521 5 0.050
steroid metabolic process GO:0008202 119 0.050
spermatogenesis GO:0007283 284 0.049
regulation of t cell activation GO:0050863 170 0.049
carbohydrate homeostasis GO:0033500 128 0.049
ribonucleotide metabolic process GO:0009259 291 0.048
regulation of transferase activity GO:0051338 263 0.048
cellular homeostasis GO:0019725 240 0.048
organic anion transport GO:0015711 137 0.048
amine metabolic process GO:0009308 45 0.046
carboxylic acid transport GO:0046942 100 0.046
regulation of secretion GO:0051046 274 0.045
immune effector process GO:0002252 321 0.045
protein modification by small protein conjugation GO:0032446 187 0.045
skeletal system development GO:0001501 356 0.045
negative regulation of phosphorus metabolic process GO:0010563 184 0.044
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.044
Mouse
wound healing GO:0042060 157 0.044
regulation of hormone levels GO:0010817 211 0.044
amino acid transmembrane transport GO:0003333 37 0.043
regulation of mapk cascade GO:0043408 248 0.043
Human Mouse
posttranscriptional regulation of gene expression GO:0010608 155 0.043
protein modification by small protein conjugation or removal GO:0070647 207 0.043
response to organic cyclic compound GO:0014070 198 0.042
regulation of protein kinase activity GO:0045859 232 0.041
ubiquitin dependent protein catabolic process GO:0006511 129 0.041
Mouse Fly
lymphocyte differentiation GO:0030098 242 0.041
nucleobase containing small molecule metabolic process GO:0055086 352 0.040
adaptive immune response GO:0002250 155 0.040
fat cell differentiation GO:0045444 160 0.040
response to molecule of bacterial origin GO:0002237 143 0.039
Mouse
defense response to other organism GO:0098542 197 0.039
regulation of multi organism process GO:0043900 111 0.039
hormone secretion GO:0046879 128 0.039
organonitrogen compound biosynthetic process GO:1901566 192 0.038
regulation of cellular catabolic process GO:0031329 242 0.038
Mouse Fly
regulation of cell activation GO:0050865 289 0.038
regulation of hydrolase activity GO:0051336 246 0.038
peptide transport GO:0015833 133 0.037
glucose homeostasis GO:0042593 128 0.037
mitotic cell cycle process GO:1903047 159 0.037
Fly
nucleoside phosphate metabolic process GO:0006753 338 0.037
dna metabolic process GO:0006259 303 0.037
transmembrane transport GO:0055085 412 0.036
cation homeostasis GO:0055080 212 0.036
negative regulation of cell cycle GO:0045786 123 0.036
Fly
proteasomal protein catabolic process GO:0010498 98 0.036
Mouse
regulation of membrane potential GO:0042391 192 0.036
negative regulation of transferase activity GO:0051348 85 0.035
modification dependent protein catabolic process GO:0019941 133 0.035
Mouse Fly
peptide hormone secretion GO:0030072 109 0.035
regulation of reactive oxygen species metabolic process GO:2000377 40 0.035
regulation of apoptotic signaling pathway GO:2001233 197 0.034
l amino acid transport GO:0015807 32 0.034
regulation of peptide secretion GO:0002791 77 0.034
amide transport GO:0042886 138 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
positive regulation of apoptotic signaling pathway GO:2001235 95 0.033
blood vessel morphogenesis GO:0048514 285 0.033
cellular response to cytokine stimulus GO:0071345 189 0.033
organic acid transport GO:0015849 101 0.033
cellular response to peptide GO:1901653 92 0.032
purine containing compound metabolic process GO:0072521 311 0.032
negative regulation of kinase activity GO:0033673 81 0.032
cellular response to dna damage stimulus GO:0006974 207 0.032
regulation of protein serine threonine kinase activity GO:0071900 157 0.031
Human
regulation of leukocyte differentiation GO:1902105 159 0.031
response to extracellular stimulus GO:0009991 127 0.031
energy derivation by oxidation of organic compounds GO:0015980 77 0.031
Mouse
regulation of cell migration GO:0030334 219 0.031
negative regulation of cellular amine metabolic process GO:0033239 1 0.031
myeloid leukocyte differentiation GO:0002573 119 0.030
alpha amino acid metabolic process GO:1901605 59 0.030
methylation GO:0032259 134 0.030
developmental maturation GO:0021700 193 0.030
ion transmembrane transport GO:0034220 361 0.030
regulation of organelle organization GO:0033043 289 0.029
Fly
muscle cell differentiation GO:0042692 261 0.029
cellular chemical homeostasis GO:0055082 215 0.029
purine nucleotide metabolic process GO:0006163 302 0.029
cation transmembrane transport GO:0098655 266 0.029
cellular response to lipopolysaccharide GO:0071222 77 0.028
male gamete generation GO:0048232 285 0.028
negative regulation of cell proliferation GO:0008285 296 0.028
inflammatory response GO:0006954 244 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.028
Mouse Fly
i kappab kinase nf kappab signaling GO:0007249 85 0.028
organic acid biosynthetic process GO:0016053 86 0.028
lipid catabolic process GO:0016042 69 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
fat soluble vitamin biosynthetic process GO:0042362 4 0.027
regulation of interleukin 8 production GO:0032677 3 0.027
sensory perception GO:0007600 245 0.027
regulation of translation GO:0006417 71 0.027
leukocyte mediated immunity GO:0002443 174 0.027
protein maturation GO:0051604 176 0.027
small molecule catabolic process GO:0044282 71 0.026
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.026
Mouse
regulation of secretion by cell GO:1903530 249 0.026
organic cyclic compound catabolic process GO:1901361 295 0.026
chromatin modification GO:0016568 187 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.026
Mouse
regulation of lipid metabolic process GO:0019216 118 0.026
regulation of peptide transport GO:0090087 91 0.026
reactive nitrogen species metabolic process GO:2001057 0 0.026
alcohol metabolic process GO:0006066 116 0.026
negative regulation of protein modification process GO:0031400 163 0.026
regulation of lymphocyte activation GO:0051249 240 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.025
sensory organ morphogenesis GO:0090596 242 0.025
regulation of ion transport GO:0043269 215 0.025
regulation of fat cell differentiation GO:0045598 81 0.025
t cell activation involved in immune response GO:0002286 43 0.025
cholesterol metabolic process GO:0008203 56 0.025
regulation of neuron differentiation GO:0045664 281 0.025
organic hydroxy compound biosynthetic process GO:1901617 77 0.024
negative regulation of fat cell differentiation GO:0045599 36 0.024
macromolecule methylation GO:0043414 120 0.024
response to topologically incorrect protein GO:0035966 25 0.024
fatty acid metabolic process GO:0006631 121 0.024
response to inorganic substance GO:0010035 96 0.024
positive regulation of defense response GO:0031349 124 0.024
cell recognition GO:0008037 83 0.024
response to nutrient levels GO:0031667 109 0.024
reactive oxygen species biosynthetic process GO:1903409 8 0.024
amino acid transport GO:0006865 61 0.024
cellular response to organonitrogen compound GO:0071417 145 0.024
rho protein signal transduction GO:0007266 32 0.024
regulation of protein catabolic process GO:0042176 108 0.024
Mouse Fly
interferon gamma production GO:0032609 67 0.024
cellular response to lipid GO:0071396 145 0.024
negative regulation of protein phosphorylation GO:0001933 126 0.023
regulation of interleukin 10 secretion GO:2001179 4 0.023
regulation of peptidase activity GO:0052547 96 0.023
homeostasis of number of cells GO:0048872 210 0.023
insulin secretion GO:0030073 89 0.023
regulation of cellular amine metabolic process GO:0033238 20 0.023
cytokine metabolic process GO:0042107 71 0.023
positive regulation of cytokine production GO:0001819 174 0.023
alpha beta t cell activation GO:0046631 91 0.023
peptide secretion GO:0002790 114 0.023
purine nucleotide biosynthetic process GO:0006164 65 0.023
interspecies interaction between organisms GO:0044419 83 0.023
lung development GO:0030324 164 0.023
Mouse
respiratory tube development GO:0030323 167 0.022
Mouse
regulation of translational initiation GO:0006446 15 0.022
eye photoreceptor cell differentiation GO:0001754 41 0.022
wnt signaling pathway GO:0016055 188 0.022
regulation of endopeptidase activity GO:0052548 89 0.022
blastocyst development GO:0001824 80 0.022
cytokine biosynthetic process GO:0042089 68 0.022
regulation of cell cycle process GO:0010564 160 0.022
Fly
peptidyl tyrosine modification GO:0018212 145 0.022
response to peptide hormone GO:0043434 127 0.022
endomembrane system organization GO:0010256 147 0.022
synaptic transmission GO:0007268 329 0.022
polysaccharide metabolic process GO:0005976 39 0.022
Mouse
regulation of innate immune response GO:0045088 91 0.022
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.021
negative regulation of cytokine production GO:0001818 84 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
positive regulation of lymphocyte activation GO:0051251 140 0.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.021
regulation of alpha beta t cell differentiation GO:0046637 35 0.021
germ cell development GO:0007281 185 0.021
cellular response to abiotic stimulus GO:0071214 56 0.021
retina development in camera type eye GO:0060041 119 0.020
regulation of hormone secretion GO:0046883 88 0.020
connective tissue development GO:0061448 179 0.020
immune response activating signal transduction GO:0002757 116 0.020
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.020
response to lipopolysaccharide GO:0032496 128 0.020
Mouse
gland development GO:0048732 330 0.020
regionalization GO:0003002 337 0.020
divalent inorganic cation homeostasis GO:0072507 138 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.020
lymphocyte activation involved in immune response GO:0002285 93 0.020
b cell activation GO:0042113 161 0.020
aromatic compound catabolic process GO:0019439 286 0.020
glucan metabolic process GO:0044042 32 0.020
Mouse
epidermis development GO:0008544 187 0.019
sterol metabolic process GO:0016125 58 0.019
nucleotide metabolic process GO:0009117 332 0.019
response to unfolded protein GO:0006986 21 0.019
nucleoside phosphate biosynthetic process GO:1901293 79 0.019
cytoplasmic transport GO:0016482 234 0.019
muscle tissue development GO:0060537 308 0.019
lymphocyte mediated immunity GO:0002449 139 0.019
anatomical structure homeostasis GO:0060249 145 0.019
lipid localization GO:0010876 126 0.018
striated muscle tissue development GO:0014706 293 0.018
negative regulation of proteolysis GO:0045861 74 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
cellular response to peptide hormone stimulus GO:0071375 92 0.018
regulation of lymphocyte differentiation GO:0045619 107 0.018
meiotic nuclear division GO:0007126 115 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
regulation of response to wounding GO:1903034 189 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
regulation of leukocyte mediated immunity GO:0002703 104 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
carboxylic acid catabolic process GO:0046395 51 0.018
regulation of cell growth GO:0001558 91 0.018
regulation of homeostatic process GO:0032844 182 0.018
positive regulation of cell activation GO:0050867 158 0.018
metal ion homeostasis GO:0055065 189 0.018
skin development GO:0043588 220 0.018
regulation of response to biotic stimulus GO:0002831 38 0.018
insulin receptor signaling pathway GO:0008286 49 0.017
positive regulation of secretion GO:0051047 130 0.017
ribose phosphate biosynthetic process GO:0046390 59 0.017
interleukin 6 production GO:0032635 58 0.017
oocyte construction GO:0007308 2 0.017
compound eye development GO:0048749 1 0.017
response to acid chemical GO:0001101 111 0.017
regulation of cell killing GO:0031341 40 0.017
regulation of cysteine type endopeptidase activity GO:2000116 65 0.017
negative regulation of defense response GO:0031348 77 0.017
hemostasis GO:0007599 78 0.017
cellular protein catabolic process GO:0044257 155 0.017
Mouse Fly
cellular glucose homeostasis GO:0001678 52 0.017
limb morphogenesis GO:0035108 149 0.017
microtubule based process GO:0007017 236 0.017
fertilization GO:0009566 127 0.017
regulation of protein processing GO:0070613 96 0.017
negative regulation of growth GO:0045926 99 0.017
organelle fission GO:0048285 170 0.016
Fly
translational initiation GO:0006413 24 0.016
epithelial cell proliferation GO:0050673 174 0.016
monocarboxylic acid transport GO:0015718 44 0.016
t cell mediated immunity GO:0002456 50 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
positive regulation of leukocyte differentiation GO:1902107 86 0.016
regulation of alpha beta t cell activation GO:0046634 53 0.016
regulation of glucose metabolic process GO:0010906 60 0.016
regulation of peptide hormone secretion GO:0090276 75 0.016
regulation of lymphocyte mediated immunity GO:0002706 84 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
Mouse Fly
second messenger mediated signaling GO:0019932 73 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
developmental cell growth GO:0048588 84 0.016
calcium ion transport GO:0006816 159 0.016
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.016
monosaccharide transport GO:0015749 58 0.016
negative regulation of cellular catabolic process GO:0031330 47 0.016
cell maturation GO:0048469 127 0.016
asymmetric stem cell division GO:0098722 3 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
regulation of interferon gamma production GO:0032649 57 0.016
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.016
negative regulation of protein processing GO:0010955 79 0.016
pallium development GO:0021543 120 0.016
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.016
Mouse
purine containing compound biosynthetic process GO:0072522 70 0.016
myosin filament organization GO:0031033 3 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
cellular response to biotic stimulus GO:0071216 92 0.016
leukocyte proliferation GO:0070661 172 0.015
regulation of neuron death GO:1901214 134 0.015
positive regulation of immune effector process GO:0002699 107 0.015
positive regulation of cell cycle GO:0045787 92 0.015
nuclear division GO:0000280 158 0.015
Fly
cellular metal ion homeostasis GO:0006875 151 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
antimicrobial peptide production GO:0002775 2 0.015
negative regulation of lymphocyte activation GO:0051250 91 0.015
protein localization to organelle GO:0033365 185 0.015
regulation of carbohydrate metabolic process GO:0006109 75 0.015
canonical wnt signaling pathway GO:0060070 130 0.015
neuromuscular process GO:0050905 99 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
leukocyte activation involved in immune response GO:0002366 126 0.015
detection of stimulus GO:0051606 84 0.015
nuclear transport GO:0051169 139 0.015
single organism cell adhesion GO:0098602 156 0.015
anion transmembrane transport GO:0098656 71 0.015
regulation of cell projection organization GO:0031344 206 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
Fly
regulation of system process GO:0044057 200 0.015
stem cell proliferation GO:0072089 117 0.015
locomotory behavior GO:0007626 195 0.015
regulation of protein maturation GO:1903317 96 0.015
interleukin 8 production GO:0032637 4 0.015
circadian rhythm GO:0007623 114 0.015
photoreceptor cell development GO:0042461 40 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
appendage development GO:0048736 166 0.015
cellular ion homeostasis GO:0006873 165 0.015
multicellular organismal signaling GO:0035637 91 0.015
positive regulation of secretion by cell GO:1903532 114 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
interleukin 10 secretion GO:0072608 4 0.015
cellular calcium ion homeostasis GO:0006874 119 0.015
limb development GO:0060173 166 0.015
epithelium migration GO:0090132 63 0.015
glucose transport GO:0015758 56 0.015
negative regulation of t helper 2 cell differentiation GO:0045629 4 0.015
negative regulation of multi organism process GO:0043901 68 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
tumor necrosis factor production GO:0032640 50 0.014
female gonad development GO:0008585 71 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
cytokine mediated signaling pathway GO:0019221 115 0.014
oocyte axis specification GO:0007309 2 0.014
cellular response to hexose stimulus GO:0071331 47 0.014
lateral inhibition GO:0046331 1 0.014
regulation of leukocyte proliferation GO:0070663 121 0.014
nuclear import GO:0051170 95 0.014
alcohol biosynthetic process GO:0046165 43 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
tissue homeostasis GO:0001894 115 0.014
sensory system development GO:0048880 3 0.014
positive regulation of nervous system development GO:0051962 221 0.014
regulation of protein complex assembly GO:0043254 83 0.014
cellular response to external stimulus GO:0071496 88 0.014
negative regulation of secretion GO:0051048 61 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
cell division GO:0051301 120 0.014
Fly
cartilage development GO:0051216 140 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
ameboidal type cell migration GO:0001667 128 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.014
cofactor metabolic process GO:0051186 80 0.014
blood circulation GO:0008015 195 0.014
cellular response to topologically incorrect protein GO:0035967 25 0.014
epithelial cell migration GO:0010631 63 0.014
dna modification GO:0006304 50 0.014
lipid homeostasis GO:0055088 63 0.014
regulation of antimicrobial humoral response GO:0002759 3 0.014
circulatory system process GO:0003013 197 0.013
leukocyte differentiation GO:0002521 342 0.013
regulation of interleukin 6 production GO:0032675 55 0.013
response to decreased oxygen levels GO:0036293 59 0.013
negative regulation of hydrolase activity GO:0051346 71 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
regulation of feeding behavior GO:0060259 3 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
embryonic appendage morphogenesis GO:0035113 126 0.013
divalent metal ion transport GO:0070838 172 0.013
detection of external stimulus GO:0009581 61 0.013
cell activation involved in immune response GO:0002263 126 0.013
regulation of lymphocyte proliferation GO:0050670 117 0.013
ras protein signal transduction GO:0007265 77 0.013
response to oxygen levels GO:0070482 62 0.013
protein secretion GO:0009306 111 0.013
regulation of chromosome organization GO:0033044 83 0.013
regulation of proteasomal protein catabolic process GO:0061136 46 0.013
Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
development of primary sexual characteristics GO:0045137 143 0.013
regulation of t cell proliferation GO:0042129 92 0.013
membrane organization GO:0061024 245 0.013
spermatid differentiation GO:0048515 115 0.013
negative regulation of secretion by cell GO:1903531 54 0.013
heterocycle catabolic process GO:0046700 280 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
Mouse Fly
apoptotic mitochondrial changes GO:0008637 48 0.013
cellular alcohol biosynthetic process GO:0044108 3 0.013
regulation of body fluid levels GO:0050878 162 0.013
regulation of vasculature development GO:1901342 88 0.013
blood coagulation GO:0007596 76 0.013
generation of precursor metabolites and energy GO:0006091 103 0.013
Mouse
appendage morphogenesis GO:0035107 149 0.013
endoplasmic reticulum unfolded protein response GO:0030968 19 0.013
vitamin d biosynthetic process GO:0042368 3 0.013
regulation of angiogenesis GO:0045765 81 0.013
regulation of inflammatory response GO:0050727 147 0.013
multi multicellular organism process GO:0044706 109 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
lymphocyte proliferation GO:0046651 164 0.012
regulation of lipid biosynthetic process GO:0046890 54 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
regulation of antimicrobial peptide production GO:0002784 1 0.012
regulation of ossification GO:0030278 112 0.012
regulation of myeloid leukocyte differentiation GO:0002761 58 0.012
phospholipid metabolic process GO:0006644 87 0.012
antimicrobial peptide biosynthetic process GO:0002777 2 0.012
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.012
skeletal system morphogenesis GO:0048705 203 0.012
negative regulation of interleukin 8 production GO:0032717 1 0.012
myotube differentiation GO:0014902 105 0.012
cellular protein complex assembly GO:0043623 116 0.012
female sex differentiation GO:0046660 84 0.012
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
cellular response to amino acid stimulus GO:0071230 29 0.012
leukocyte apoptotic process GO:0071887 71 0.012
natural killer cell mediated immunity GO:0002228 29 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
response to starvation GO:0042594 65 0.012
rna processing GO:0006396 105 0.012
defense response to bacterium GO:0042742 119 0.012

Trib3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.037
neuropathy DOID:870 0 0.037
neuromuscular disease DOID:440 0 0.035
sensory system disease DOID:0050155 0 0.018
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.015
central nervous system disease DOID:331 0 0.015
disease of metabolism DOID:0014667 0 0.014
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.013
neurodegenerative disease DOID:1289 0 0.012