Mus musculus

19 known processes

Dhtkd1

dehydrogenase E1 and transketolase domain containing 1

(Aliases: C330018I04Rik)

Dhtkd1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.107
purine ribonucleotide metabolic process GO:0009150 290 0.069
amine metabolic process GO:0009308 45 0.065
cellular lipid metabolic process GO:0044255 323 0.065
nucleoside phosphate metabolic process GO:0006753 338 0.061
cellular ketone metabolic process GO:0042180 84 0.058
nucleobase containing small molecule metabolic process GO:0055086 352 0.058
cellular amine metabolic process GO:0044106 44 0.055
organonitrogen compound catabolic process GO:1901565 264 0.048
cellular nitrogen compound catabolic process GO:0044270 280 0.046
regulation of cellular ketone metabolic process GO:0010565 66 0.044
oxidation reduction process GO:0055114 342 0.044
nucleotide metabolic process GO:0009117 332 0.043
purine containing compound metabolic process GO:0072521 311 0.042
purine nucleotide metabolic process GO:0006163 302 0.040
lipid biosynthetic process GO:0008610 179 0.039
organic cyclic compound catabolic process GO:1901361 295 0.037
ribonucleotide metabolic process GO:0009259 291 0.037
heterocycle catabolic process GO:0046700 280 0.036
transmembrane transport GO:0055085 412 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.036
ribose phosphate metabolic process GO:0019693 291 0.036
cofactor metabolic process GO:0051186 80 0.035
regulation of cellular amine metabolic process GO:0033238 20 0.035
aromatic compound catabolic process GO:0019439 286 0.034
response to organonitrogen compound GO:0010243 246 0.033
membrane organization GO:0061024 245 0.032
cellular homeostasis GO:0019725 240 0.032
organonitrogen compound biosynthetic process GO:1901566 192 0.031
spermatogenesis GO:0007283 284 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
glycerolipid metabolic process GO:0046486 122 0.028
male gamete generation GO:0048232 285 0.028
purine nucleoside triphosphate metabolic process GO:0009144 226 0.028
purine ribonucleoside metabolic process GO:0046128 241 0.028
regulation of organelle organization GO:0033043 289 0.028
peptidyl amino acid modification GO:0018193 336 0.027
macromolecule catabolic process GO:0009057 281 0.027
organophosphate catabolic process GO:0046434 232 0.026
renal system development GO:0072001 225 0.026
ribonucleoside triphosphate metabolic process GO:0009199 220 0.026
alpha amino acid metabolic process GO:1901605 59 0.026
negative regulation of protein metabolic process GO:0051248 282 0.025
glycosyl compound metabolic process GO:1901657 246 0.025
ribonucleoside metabolic process GO:0009119 245 0.025
urogenital system development GO:0001655 261 0.025
positive regulation of apoptotic process GO:0043065 217 0.025
developmental maturation GO:0021700 193 0.025
nucleoside triphosphate metabolic process GO:0009141 230 0.024
regulation of cellular catabolic process GO:0031329 242 0.024
skeletal system development GO:0001501 356 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
small molecule biosynthetic process GO:0044283 132 0.024
organic hydroxy compound metabolic process GO:1901615 203 0.024
nitrogen compound transport GO:0071705 271 0.024
ion transmembrane transport GO:0034220 361 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.023
nucleoside phosphate catabolic process GO:1901292 222 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.023
regulation of hormone levels GO:0010817 211 0.023
apoptotic signaling pathway GO:0097190 306 0.023
protein catabolic process GO:0030163 221 0.023
reactive oxygen species metabolic process GO:0072593 84 0.023
purine nucleoside metabolic process GO:0042278 241 0.022
kidney development GO:0001822 213 0.022
response to organic cyclic compound GO:0014070 198 0.022
meiotic cell cycle GO:0051321 122 0.022
anion transport GO:0006820 177 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
alcohol metabolic process GO:0006066 116 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.022
cation transmembrane transport GO:0098655 266 0.022
ribonucleoside catabolic process GO:0042454 206 0.022
dna metabolic process GO:0006259 303 0.022
regulation of nucleotide metabolic process GO:0006140 169 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
organelle fission GO:0048285 170 0.021
fat cell differentiation GO:0045444 160 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
myeloid cell differentiation GO:0030099 233 0.021
ras protein signal transduction GO:0007265 77 0.021
nucleotide catabolic process GO:0009166 217 0.021
cellular chemical homeostasis GO:0055082 215 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
regulation of secretion GO:0051046 274 0.021
camera type eye development GO:0043010 266 0.021
cation transport GO:0006812 399 0.021
fatty acid metabolic process GO:0006631 121 0.021
carbohydrate metabolic process GO:0005975 230 0.020
positive regulation of protein modification process GO:0031401 299 0.020
regulation of protein localization GO:0032880 231 0.020
cation homeostasis GO:0055080 212 0.020
purine containing compound catabolic process GO:0072523 213 0.020
nucleoside metabolic process GO:0009116 246 0.020
monocarboxylic acid metabolic process GO:0032787 191 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
glycosyl compound catabolic process GO:1901658 206 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
nuclear division GO:0000280 158 0.019
protein ubiquitination GO:0016567 171 0.019
cell adhesion GO:0007155 329 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
negative regulation of protein modification process GO:0031400 163 0.019
nucleoside catabolic process GO:0009164 206 0.019
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
regulation of mapk cascade GO:0043408 248 0.019
fat soluble vitamin biosynthetic process GO:0042362 4 0.019
cell maturation GO:0048469 127 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
rho protein signal transduction GO:0007266 32 0.018
cellular protein catabolic process GO:0044257 155 0.018
purine nucleotide catabolic process GO:0006195 211 0.018
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
protein localization to organelle GO:0033365 185 0.018
sensory perception GO:0007600 245 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
regulation of membrane potential GO:0042391 192 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
organic acid biosynthetic process GO:0016053 86 0.018
regulation of secretion by cell GO:1903530 249 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
mapk cascade GO:0000165 281 0.018
meiotic nuclear division GO:0007126 115 0.018
small molecule catabolic process GO:0044282 71 0.017
regulation of protein kinase activity GO:0045859 232 0.017
ossification GO:0001503 216 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
cellular alcohol biosynthetic process GO:0044108 3 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
positive regulation of cell death GO:0010942 224 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
respiratory system development GO:0060541 190 0.017
cellular amino acid catabolic process GO:0009063 25 0.017
carbohydrate homeostasis GO:0033500 128 0.017
protein modification by small protein conjugation GO:0032446 187 0.016
response to acid chemical GO:0001101 111 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
organic anion transport GO:0015711 137 0.016
spermatid differentiation GO:0048515 115 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
steroid metabolic process GO:0008202 119 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
germ cell development GO:0007281 185 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
sulfur compound metabolic process GO:0006790 100 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
homeostasis of number of cells GO:0048872 210 0.016
coenzyme metabolic process GO:0006732 52 0.016
regulation of hydrolase activity GO:0051336 246 0.016
multicellular organism growth GO:0035264 161 0.016
peptide transport GO:0015833 133 0.015
glycerophospholipid metabolic process GO:0006650 71 0.015
maintenance of location GO:0051235 89 0.015
microtubule based process GO:0007017 236 0.015
gland development GO:0048732 330 0.015
skin development GO:0043588 220 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.015
striated muscle tissue development GO:0014706 293 0.015
amide transport GO:0042886 138 0.015
cytoplasmic transport GO:0016482 234 0.015
intracellular protein transport GO:0006886 204 0.015
modification dependent macromolecule catabolic process GO:0043632 133 0.015
regulation of kinase activity GO:0043549 249 0.015
cellular carbohydrate metabolic process GO:0044262 119 0.015
response to extracellular stimulus GO:0009991 127 0.015
hormone secretion GO:0046879 128 0.015
cell type specific apoptotic process GO:0097285 268 0.015
muscle tissue development GO:0060537 308 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
neural tube development GO:0021915 160 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
response to peptide GO:1901652 136 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
regulation of anatomical structure size GO:0090066 178 0.014
positive regulation of cell development GO:0010720 237 0.014
leukocyte differentiation GO:0002521 342 0.014
tube formation GO:0035148 140 0.014
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
multicellular organismal signaling GO:0035637 91 0.014
response to radiation GO:0009314 165 0.014
skeletal system morphogenesis GO:0048705 203 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
mitotic cell cycle process GO:1903047 159 0.014
innate immune response GO:0045087 157 0.014
cellular response to lipid GO:0071396 145 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
chromatin organization GO:0006325 206 0.014
modification dependent protein catabolic process GO:0019941 133 0.014
response to peptide hormone GO:0043434 127 0.014
peptide secretion GO:0002790 114 0.014
cytokine production GO:0001816 319 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
muscle cell differentiation GO:0042692 261 0.014
cellular alcohol metabolic process GO:0044107 3 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
anatomical structure homeostasis GO:0060249 145 0.013
organic acid transport GO:0015849 101 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
endomembrane system organization GO:0010256 147 0.013
respiratory tube development GO:0030323 167 0.013
epithelial cell development GO:0002064 159 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
regulation of system process GO:0044057 200 0.013
organelle localization GO:0051640 179 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
spermatid development GO:0007286 108 0.013
energy derivation by oxidation of organic compounds GO:0015980 77 0.013
plasma membrane organization GO:0007009 90 0.013
stem cell differentiation GO:0048863 268 0.013
cellular ion homeostasis GO:0006873 165 0.013
regulation of transferase activity GO:0051338 263 0.013
response to nutrient levels GO:0031667 109 0.013
negative regulation of molecular function GO:0044092 258 0.013
fertilization GO:0009566 127 0.013
neuronal action potential GO:0019228 54 0.013
transmission of nerve impulse GO:0019226 76 0.013
lung development GO:0030324 164 0.013
morphogenesis of a branching structure GO:0001763 203 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.013
blood circulation GO:0008015 195 0.013
response to inorganic substance GO:0010035 96 0.013
synaptic transmission GO:0007268 329 0.013
protein localization to membrane GO:0072657 108 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
regulation of cell activation GO:0050865 289 0.012
phospholipid metabolic process GO:0006644 87 0.012
rna interference GO:0016246 2 0.012
regulation of proteolysis GO:0030162 164 0.012
generation of precursor metabolites and energy GO:0006091 103 0.012
Human
connective tissue development GO:0061448 179 0.012
immune effector process GO:0002252 321 0.012
forebrain development GO:0030900 302 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
meiotic cell cycle process GO:1903046 77 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
purine containing compound biosynthetic process GO:0072522 70 0.012
cellular modified amino acid metabolic process GO:0006575 63 0.012
peptide hormone secretion GO:0030072 109 0.012
regulation of homeostatic process GO:0032844 182 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
epidermis development GO:0008544 187 0.012
lipid localization GO:0010876 126 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
bone development GO:0060348 120 0.012
acetate metabolic process GO:0006083 1 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
action potential GO:0001508 78 0.012
mitotic cell cycle GO:0000278 195 0.012
regulation of protein catabolic process GO:0042176 108 0.012
meiosis i GO:0007127 60 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
regulation of cell cycle GO:0051726 281 0.012
localization within membrane GO:0051668 4 0.012
naphthalene containing compound metabolic process GO:0090420 1 0.012
glucose homeostasis GO:0042593 128 0.012
nucleoside phosphate biosynthetic process GO:1901293 79 0.012
tissue homeostasis GO:0001894 115 0.012
oocyte construction GO:0007308 2 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
nephron development GO:0072006 109 0.011
organic acid catabolic process GO:0016054 51 0.011
neuron apoptotic process GO:0051402 142 0.011
carboxylic acid catabolic process GO:0046395 51 0.011
regulation of neuron differentiation GO:0045664 281 0.011
regulation of cell projection organization GO:0031344 206 0.011
lipid transport GO:0006869 98 0.011
defense response to other organism GO:0098542 197 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
stem cell development GO:0048864 219 0.011
skeletal muscle organ development GO:0060538 163 0.011
wnt signaling pathway GO:0016055 188 0.011
development of primary sexual characteristics GO:0045137 143 0.011
positive regulation of nervous system development GO:0051962 221 0.011
cellular response to cadmium ion GO:0071276 3 0.011
regulation of protein transport GO:0051223 163 0.011
protein localization to nucleus GO:0034504 121 0.011
chromosome organization involved in meiosis GO:0070192 39 0.011
sequestering of calcium ion GO:0051208 18 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
digestive system development GO:0055123 200 0.011
neural tube closure GO:0001843 90 0.011
actin cytoskeleton organization GO:0030036 220 0.011
regulation of intracellular transport GO:0032386 159 0.011
regulation of fat cell differentiation GO:0045598 81 0.011
actin filament organization GO:0007015 113 0.011
asymmetric stem cell division GO:0098722 3 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
membrane lipid metabolic process GO:0006643 53 0.011
response to oxidative stress GO:0006979 123 0.011
ribose phosphate biosynthetic process GO:0046390 59 0.011
glycerolipid biosynthetic process GO:0045017 50 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
endocytosis GO:0006897 168 0.011
regionalization GO:0003002 337 0.011
epithelial tube formation GO:0072175 130 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
cell cell junction organization GO:0045216 72 0.011
atp metabolic process GO:0046034 75 0.011
calcitriol biosynthetic process from calciol GO:0036378 3 0.011
gonad development GO:0008406 141 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
regulation of ossification GO:0030278 112 0.011
translation GO:0006412 93 0.011
lymphocyte differentiation GO:0030098 242 0.011
purine nucleotide biosynthetic process GO:0006164 65 0.010
regulation of lymphocyte activation GO:0051249 240 0.010
rhythmic process GO:0048511 174 0.010
response to light stimulus GO:0009416 135 0.010
cellularization GO:0007349 1 0.010
metal ion homeostasis GO:0055065 189 0.010
negative regulation of phosphorylation GO:0042326 166 0.010
sensory organ morphogenesis GO:0090596 242 0.010
circulatory system process GO:0003013 197 0.010
negative regulation of cell development GO:0010721 169 0.010
synapsis GO:0007129 34 0.010
kidney epithelium development GO:0072073 121 0.010
dendrite development GO:0016358 115 0.010
neutral lipid metabolic process GO:0006638 57 0.010
cellular response to peptide GO:1901653 92 0.010
neuron death GO:0070997 154 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010
t cell activation GO:0042110 289 0.010
regulation of nucleotide catabolic process GO:0030811 122 0.010
dephosphorylation GO:0016311 129 0.010
developmental growth involved in morphogenesis GO:0060560 138 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
regulation of purine nucleotide catabolic process GO:0033121 122 0.010
carboxylic acid transport GO:0046942 100 0.010
embryonic epithelial tube formation GO:0001838 130 0.010
response to growth factor GO:0070848 198 0.010

Dhtkd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.028
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
inherited metabolic disorder DOID:655 0 0.020
central nervous system disease DOID:331 0 0.017
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.012
immune system disease DOID:2914 0 0.012
hematopoietic system disease DOID:74 0 0.012
disease of cellular proliferation DOID:14566 0 0.011
neurodegenerative disease DOID:1289 0 0.010
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010