Mus musculus

87 known processes

Zic5

zinc finger protein of the cerebellum 5

(Aliases: 1700049L20Rik,Opr)

Zic5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 44 0.083
camera type eye development GO:0043010 266 0.082
transmembrane transport GO:0055085 412 0.074
cellular amino acid metabolic process GO:0006520 103 0.067
axonogenesis GO:0007409 274 0.063
Mouse
retina development in camera type eye GO:0060041 119 0.061
neural tube development GO:0021915 160 0.059
positive regulation of cell development GO:0010720 237 0.059
sensory perception GO:0007600 245 0.057
Mouse
regionalization GO:0003002 337 0.057
Mouse
regulation of neuron differentiation GO:0045664 281 0.057
forebrain development GO:0030900 302 0.053
regulation of cellular ketone metabolic process GO:0010565 66 0.052
peptidyl amino acid modification GO:0018193 336 0.048
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.047
Fly
embryonic epithelial tube formation GO:0001838 130 0.046
neural tube closure GO:0001843 90 0.044
cellular ketone metabolic process GO:0042180 84 0.043
skeletal system development GO:0001501 356 0.043
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.043
gland development GO:0048732 330 0.043
telencephalon development GO:0021537 186 0.042
spermatid differentiation GO:0048515 115 0.042
stem cell development GO:0048864 219 0.042
negative regulation of cell development GO:0010721 169 0.042
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.041
amine metabolic process GO:0009308 45 0.041
sensory organ morphogenesis GO:0090596 242 0.041
regulation of organelle organization GO:0033043 289 0.041
negative regulation of cellular amine metabolic process GO:0033239 1 0.040
stem cell differentiation GO:0048863 268 0.040
regulation of neuron apoptotic process GO:0043523 122 0.040
central nervous system neuron differentiation GO:0021953 162 0.039
tube formation GO:0035148 140 0.039
neural precursor cell proliferation GO:0061351 121 0.039
Zebrafish
ear development GO:0043583 200 0.038
muscle tissue development GO:0060537 308 0.038
epithelial cell development GO:0002064 159 0.038
striated muscle tissue development GO:0014706 293 0.038
synaptic transmission GO:0007268 329 0.037
male gamete generation GO:0048232 285 0.036
epithelial tube morphogenesis GO:0060562 303 0.035
fat cell differentiation GO:0045444 160 0.035
neuron migration GO:0001764 122 0.035
regulation of cellular amine metabolic process GO:0033238 20 0.035
positive regulation of protein modification process GO:0031401 299 0.034
dendrite development GO:0016358 115 0.034
negative regulation of nervous system development GO:0051961 156 0.034
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
developmental maturation GO:0021700 193 0.033
cellular lipid metabolic process GO:0044255 323 0.032
negative regulation of molecular function GO:0044092 258 0.032
positive regulation of protein phosphorylation GO:0001934 242 0.032
spermatogenesis GO:0007283 284 0.032
chromatin organization GO:0006325 206 0.032
spermatid development GO:0007286 108 0.032
myeloid cell differentiation GO:0030099 233 0.031
germ cell development GO:0007281 185 0.031
small gtpase mediated signal transduction GO:0007264 97 0.031
negative regulation of protein metabolic process GO:0051248 282 0.031
negative regulation of neuron differentiation GO:0045665 101 0.031
neural tube formation GO:0001841 108 0.030
ion transmembrane transport GO:0034220 361 0.030
morphogenesis of embryonic epithelium GO:0016331 159 0.030
cell fate commitment GO:0045165 210 0.030
Worm
regulation of cellular amino acid metabolic process GO:0006521 5 0.030
positive regulation of neuron differentiation GO:0045666 141 0.029
mesoderm development GO:0007498 100 0.029
heart morphogenesis GO:0003007 178 0.029
Mouse
muscle cell differentiation GO:0042692 261 0.029
negative regulation of neuron death GO:1901215 98 0.029
regulation of neuron projection development GO:0010975 169 0.029
neuron apoptotic process GO:0051402 142 0.028
cell adhesion GO:0007155 329 0.028
gliogenesis GO:0042063 141 0.028
protein localization to organelle GO:0033365 185 0.028
Mouse
lateral inhibition GO:0046331 1 0.027
inorganic ion transmembrane transport GO:0098660 234 0.027
cell type specific apoptotic process GO:0097285 268 0.027
pallium development GO:0021543 120 0.027
respiratory system development GO:0060541 190 0.026
regulation of neuron death GO:1901214 134 0.026
positive regulation of organelle organization GO:0010638 128 0.026
skin development GO:0043588 220 0.026
urogenital system development GO:0001655 261 0.026
negative regulation of cell proliferation GO:0008285 296 0.026
tube closure GO:0060606 91 0.025
protein modification by small protein conjugation or removal GO:0070647 207 0.025
regulation of kinase activity GO:0043549 249 0.025
organelle fission GO:0048285 170 0.025
negative regulation of cellular component organization GO:0051129 194 0.025
microtubule based process GO:0007017 236 0.024
bmp signaling pathway GO:0030509 93 0.024
regulation of cell projection organization GO:0031344 206 0.024
positive regulation of nervous system development GO:0051962 221 0.024
chemotaxis GO:0006935 247 0.024
Mouse
erythrocyte differentiation GO:0030218 88 0.024
renal system development GO:0072001 225 0.024
immune effector process GO:0002252 321 0.024
neuromuscular process GO:0050905 99 0.024
regulation of cell cycle GO:0051726 281 0.023
determination of left right asymmetry in nervous system GO:0035545 1 0.023
Mouse
epithelial tube formation GO:0072175 130 0.023
mitochondrion organization GO:0007005 134 0.023
fertilization GO:0009566 127 0.023
organelle localization GO:0051640 179 0.023
diencephalon development GO:0021536 63 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.023
regulation of cell cycle process GO:0010564 160 0.023
neuron death GO:0070997 154 0.023
cerebral cortex development GO:0021987 86 0.022
chromatin modification GO:0016568 187 0.022
neuron projection guidance GO:0097485 141 0.022
Mouse
homeostasis of number of cells GO:0048872 210 0.022
limb morphogenesis GO:0035108 149 0.022
appendage development GO:0048736 166 0.022
regulation of organ morphogenesis GO:2000027 144 0.022
carbohydrate metabolic process GO:0005975 230 0.021
connective tissue development GO:0061448 179 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.021
segmentation GO:0035282 93 0.021
regulation of transferase activity GO:0051338 263 0.021
regulation of binding GO:0051098 111 0.021
nuclear division GO:0000280 158 0.021
developmental growth involved in morphogenesis GO:0060560 138 0.020
blood vessel morphogenesis GO:0048514 285 0.020
cytoplasmic transport GO:0016482 234 0.020
Mouse
central nervous system neuron development GO:0021954 67 0.020
exocytosis GO:0006887 121 0.020
primary neural tube formation GO:0014020 95 0.020
embryonic organ morphogenesis GO:0048562 276 0.020
Mouse
negative regulation of organelle organization GO:0010639 90 0.020
covalent chromatin modification GO:0016569 163 0.020
ventricular system development GO:0021591 27 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
microtubule based movement GO:0007018 84 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
regulation of system process GO:0044057 200 0.019
regulation of mitotic cell cycle GO:0007346 126 0.019
nuclear transport GO:0051169 139 0.019
Mouse
negative regulation of neuron apoptotic process GO:0043524 92 0.019
histone modification GO:0016570 159 0.019
negative regulation of protein modification process GO:0031400 163 0.019
cellular response to growth factor stimulus GO:0071363 197 0.018
cardiac chamber development GO:0003205 108 0.018
leukocyte differentiation GO:0002521 342 0.018
stem cell proliferation GO:0072089 117 0.018
cation transport GO:0006812 399 0.018
lymphocyte differentiation GO:0030098 242 0.018
locomotory behavior GO:0007626 195 0.018
Mouse
negative regulation of phosphorylation GO:0042326 166 0.018
cell maturation GO:0048469 127 0.018
epidermis development GO:0008544 187 0.018
organelle assembly GO:0070925 177 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
oxidation reduction process GO:0055114 342 0.018
myeloid cell homeostasis GO:0002262 114 0.017
phospholipid metabolic process GO:0006644 87 0.017
endomembrane system organization GO:0010256 147 0.017
cell division GO:0051301 120 0.017
cellular response to dna damage stimulus GO:0006974 207 0.017
cardiac chamber morphogenesis GO:0003206 93 0.017
anion transport GO:0006820 177 0.017
multicellular organism growth GO:0035264 161 0.017
regulation of histone modification GO:0031056 56 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
protein maturation GO:0051604 176 0.017
nitrogen compound transport GO:0071705 271 0.017
kidney development GO:0001822 213 0.017
skeletal system morphogenesis GO:0048705 203 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
gonad development GO:0008406 141 0.016
Worm
compound eye development GO:0048749 1 0.016
spinal cord development GO:0021510 81 0.016
Mouse
intracellular protein transport GO:0006886 204 0.016
Mouse
regulation of actin filament based process GO:0032970 99 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
ras protein signal transduction GO:0007265 77 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
cation homeostasis GO:0055080 212 0.016
central nervous system projection neuron axonogenesis GO:0021952 21 0.016
somitogenesis GO:0001756 69 0.016
palate development GO:0060021 76 0.016
hindbrain development GO:0030902 128 0.016
regulation of bmp signaling pathway GO:0030510 60 0.016
myelination GO:0042552 74 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
bone development GO:0060348 120 0.016
photoreceptor cell differentiation GO:0046530 52 0.016
macromolecule catabolic process GO:0009057 281 0.015
regulation of wnt signaling pathway GO:0030111 123 0.015
digestive tract development GO:0048565 190 0.015
Fly
cardiac ventricle development GO:0003231 83 0.015
lymphocyte mediated immunity GO:0002449 139 0.015
cellular protein complex assembly GO:0043623 116 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
protein catabolic process GO:0030163 221 0.015
appendage morphogenesis GO:0035107 149 0.015
b cell differentiation GO:0030183 78 0.015
morphogenesis of a branching epithelium GO:0061138 193 0.015
cellular carbohydrate metabolic process GO:0044262 119 0.015
oocyte axis specification GO:0007309 2 0.015
positive regulation of intracellular protein transport GO:0090316 42 0.015
Mouse
regulation of intracellular transport GO:0032386 159 0.015
Mouse
cellular chemical homeostasis GO:0055082 215 0.015
response to growth factor GO:0070848 198 0.015
neural retina development GO:0003407 41 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
tendon formation GO:0035992 4 0.015
regulation of cell motility GO:2000145 236 0.015
motor neuron migration GO:0097475 4 0.015
development of primary sexual characteristics GO:0045137 143 0.015
Worm
positive regulation of cell cycle GO:0045787 92 0.015
establishment of protein localization to organelle GO:0072594 118 0.015
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.015
gastrulation GO:0007369 116 0.015
myotube differentiation GO:0014902 105 0.015
mitochondrion distribution GO:0048311 4 0.015
protein localization to nucleus GO:0034504 121 0.015
Mouse
limbic system development GO:0021761 72 0.015
retina morphogenesis in camera type eye GO:0060042 45 0.015
glial cell differentiation GO:0010001 131 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
skeletal muscle organ development GO:0060538 163 0.014
limb development GO:0060173 166 0.014
action potential GO:0001508 78 0.014
metencephalon development GO:0022037 89 0.014
peripheral nervous system neuron axonogenesis GO:0048936 3 0.014
positive regulation of cell motility GO:2000147 116 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
sensory system development GO:0048880 3 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
tissue homeostasis GO:0001894 115 0.014
oocyte construction GO:0007308 2 0.014
auditory receptor cell fate determination GO:0042668 3 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
epithelium migration GO:0090132 63 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
Mouse
regulation of auditory receptor cell differentiation GO:0045607 4 0.013
transmission of nerve impulse GO:0019226 76 0.013
central nervous system neuron axonogenesis GO:0021955 28 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
stem cell maintenance GO:0019827 130 0.013
mitotic cell cycle process GO:1903047 159 0.013
multi multicellular organism process GO:0044706 109 0.013
Worm
axon ensheathment GO:0008366 76 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
somite development GO:0061053 81 0.013
maintenance of location GO:0051235 89 0.013
Worm
dna metabolic process GO:0006259 303 0.013
b cell activation GO:0042113 161 0.013
neuronal action potential GO:0019228 54 0.013
hair cell differentiation GO:0035315 40 0.013
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.013
morphogenesis of a branching structure GO:0001763 203 0.013
protein targeting GO:0006605 143 0.013
Mouse
negative regulation of osteoblast differentiation GO:0045668 30 0.013
corpus callosum morphogenesis GO:0021540 3 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
positive regulation of kinase activity GO:0033674 155 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.013
angiogenesis GO:0001525 201 0.013
ossification GO:0001503 216 0.013
digestive tract morphogenesis GO:0048546 147 0.013
respiratory tube development GO:0030323 167 0.013
adult behavior GO:0030534 135 0.013
Mouse
inner ear morphogenesis GO:0042472 101 0.013
mapk cascade GO:0000165 281 0.013
calcium ion dependent exocytosis GO:0017156 35 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
regulation of translation GO:0006417 71 0.012
metal ion homeostasis GO:0055065 189 0.012
rho protein signal transduction GO:0007266 32 0.012
adaptive immune response GO:0002250 155 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
skeletal muscle cell differentiation GO:0035914 66 0.012
carboxylic acid transport GO:0046942 100 0.012
response to organic cyclic compound GO:0014070 198 0.012
positive regulation of cell death GO:0010942 224 0.012
nephron epithelium development GO:0072009 92 0.012
meiotic nuclear division GO:0007126 115 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
protein ubiquitination GO:0016567 171 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.012
cation transmembrane transport GO:0098655 266 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
muscle cell development GO:0055001 133 0.012
nucleoside metabolic process GO:0009116 246 0.012
spinal cord motor neuron differentiation GO:0021522 35 0.012
microtubule based transport GO:0010970 50 0.012
cell differentiation involved in kidney development GO:0061005 33 0.012
protein polymerization GO:0051258 57 0.012
cell proliferation in forebrain GO:0021846 30 0.012
regulation of neural retina development GO:0061074 3 0.012
auditory receptor cell differentiation GO:0042491 37 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
protein processing GO:0016485 163 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
dephosphorylation GO:0016311 129 0.012
regulation of protein complex assembly GO:0043254 83 0.012
visceral motor neuron differentiation GO:0021524 3 0.012
vesicle organization GO:0016050 60 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
single fertilization GO:0007338 82 0.012
potassium ion homeostasis GO:0055075 4 0.012
leukocyte mediated immunity GO:0002443 174 0.011
tendon cell differentiation GO:0035990 4 0.011
positive regulation of keratinocyte proliferation GO:0010838 4 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
transdifferentiation GO:0060290 1 0.011
meiosis i GO:0007127 60 0.011
cell recognition GO:0008037 83 0.011
regulation of ossification GO:0030278 112 0.011
cell growth GO:0016049 130 0.011
regulation of exocytosis GO:0017157 61 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
establishment or maintenance of cell polarity GO:0007163 86 0.011
regulation of stem cell proliferation GO:0072091 78 0.011
formation of primary germ layer GO:0001704 77 0.011
synapse organization GO:0050808 125 0.011
positive regulation of mitotic cell cycle GO:0045931 41 0.011
regulation of striated muscle cell differentiation GO:0051153 81 0.011
apoptotic signaling pathway GO:0097190 306 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
positive regulation of intracellular transport GO:0032388 70 0.011
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
Mouse
embryonic appendage morphogenesis GO:0035113 126 0.011
positive regulation of transferase activity GO:0051347 167 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
lung development GO:0030324 164 0.011
inner ear receptor cell differentiation GO:0060113 61 0.011
odontogenesis GO:0042476 78 0.011
establishment or maintenance of apical basal cell polarity GO:0035088 21 0.011
organic acid transport GO:0015849 101 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
positive regulation of cell migration GO:0030335 109 0.011
digestive system development GO:0055123 200 0.011
Fly
sensory perception of sound GO:0007605 97 0.011
dna recombination GO:0006310 92 0.011
regulation of neural precursor cell proliferation GO:2000177 70 0.011
regulation of chromatin modification GO:1903308 57 0.011
cell activation involved in immune response GO:0002263 126 0.011
ameboidal type cell migration GO:0001667 128 0.011
heart process GO:0003015 94 0.011
t cell activation GO:0042110 289 0.011
rna processing GO:0006396 105 0.011
response to organonitrogen compound GO:0010243 246 0.011
regulation of muscle tissue development GO:1901861 97 0.011
regulation of protein localization GO:0032880 231 0.011
Mouse
regulation of anatomical structure size GO:0090066 178 0.011
neuroblast differentiation GO:0014016 2 0.011
translation GO:0006412 93 0.010
cartilage development GO:0051216 140 0.010
nucleobase containing small molecule metabolic process GO:0055086 352 0.010
positive regulation of cell cycle process GO:0090068 61 0.010
regulation of membrane potential GO:0042391 192 0.010
endodermal cell fate specification GO:0001714 4 0.010
regulation of chromatin organization GO:1902275 57 0.010
developmental cell growth GO:0048588 84 0.010
methylation GO:0032259 134 0.010
nucleoside triphosphate metabolic process GO:0009141 230 0.010
monocarboxylic acid metabolic process GO:0032787 191 0.010
meiotic cell cycle process GO:1903046 77 0.010
wnt signaling pathway GO:0016055 188 0.010
Zebrafish
mesodermal cell migration GO:0008078 4 0.010
multicellular organismal signaling GO:0035637 91 0.010
cerebral cortex radially oriented cell migration GO:0021799 31 0.010
membrane organization GO:0061024 245 0.010
negative regulation of ossification GO:0030279 49 0.010
meiotic cell cycle GO:0051321 122 0.010
macromolecule methylation GO:0043414 120 0.010
notch signaling pathway GO:0007219 71 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.010
regulation of transmembrane transport GO:0034762 128 0.010

Zic5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 0 0.018
disease of anatomical entity DOID:7 0 0.018
musculoskeletal system disease DOID:17 0 0.018
connective tissue disease DOID:65 0 0.018
nervous system disease DOID:863 0 0.016
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
physical disorder DOID:0080015 0 0.011
congenital nervous system abnormality DOID:2490 0 0.011
organ system cancer DOID:0050686 0 0.010