Mus musculus

147 known processes

Arhgef7

Rho guanine nucleotide exchange factor (GEF7)

(Aliases: p85SPR,betaPix,cool-1,mKIAA0142,betaPix-c,betaPix-b,Pak3bp,PIX,p85Cool1,Cool)

Arhgef7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
guanosine containing compound catabolic process GO:1901069 144 0.964
cellular response to oxidative stress GO:0034599 76 0.952
ribonucleoside metabolic process GO:0009119 245 0.914
nucleoside triphosphate catabolic process GO:0009143 205 0.893
nucleotide catabolic process GO:0009166 217 0.888
organophosphate catabolic process GO:0046434 232 0.884
guanosine containing compound metabolic process GO:1901068 144 0.881
purine ribonucleoside catabolic process GO:0046130 205 0.865
organonitrogen compound catabolic process GO:1901565 264 0.865
nucleoside catabolic process GO:0009164 206 0.860
regulation of rho gtpase activity GO:0032319 58 0.855
nucleoside metabolic process GO:0009116 246 0.854
ribonucleoside triphosphate catabolic process GO:0009203 199 0.853
gtp metabolic process GO:0046039 144 0.845
purine ribonucleotide catabolic process GO:0009154 208 0.831
aromatic compound catabolic process GO:0019439 286 0.824
regulation of nucleoside metabolic process GO:0009118 130 0.819
positive regulation of gtpase activity GO:0043547 85 0.818
purine nucleoside catabolic process GO:0006152 205 0.817
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.814
ribonucleotide catabolic process GO:0009261 208 0.792
nucleoside phosphate metabolic process GO:0006753 338 0.791
purine ribonucleoside metabolic process GO:0046128 241 0.782
purine containing compound catabolic process GO:0072523 213 0.777
glycosyl compound catabolic process GO:1901658 206 0.771
nucleoside triphosphate metabolic process GO:0009141 230 0.761
nucleoside phosphate catabolic process GO:1901292 222 0.756
cellular nitrogen compound catabolic process GO:0044270 280 0.751
purine ribonucleotide metabolic process GO:0009150 290 0.734
proteasomal protein catabolic process GO:0010498 98 0.722
regulation of gtp catabolic process GO:0033124 113 0.722
organic cyclic compound catabolic process GO:1901361 295 0.714
purine nucleotide catabolic process GO:0006195 211 0.711
regulation of nucleotide metabolic process GO:0006140 169 0.710
lamellipodium organization GO:0097581 29 0.700
regulation of purine nucleotide catabolic process GO:0033121 122 0.699
glycosyl compound metabolic process GO:1901657 246 0.696
positive regulation of gtp catabolic process GO:0033126 85 0.688
regulation of epithelial cell proliferation GO:0050678 141 0.685
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.679
ras protein signal transduction GO:0007265 77 0.674
regulation of autophagy GO:0010506 30 0.671
ribose phosphate metabolic process GO:0019693 291 0.667
purine nucleoside triphosphate metabolic process GO:0009144 226 0.666
nucleotide metabolic process GO:0009117 332 0.660
modification dependent macromolecule catabolic process GO:0043632 133 0.644
carbohydrate derivative catabolic process GO:1901136 231 0.642
heterocycle catabolic process GO:0046700 280 0.642
ribonucleotide metabolic process GO:0009259 291 0.629
response to oxidative stress GO:0006979 123 0.623
purine nucleoside triphosphate catabolic process GO:0009146 203 0.609
gtp catabolic process GO:0006184 143 0.595
positive regulation of nucleotide catabolic process GO:0030813 88 0.586
ubiquitin dependent protein catabolic process GO:0006511 129 0.575
purine containing compound metabolic process GO:0072521 311 0.571
regulation of nucleotide catabolic process GO:0030811 122 0.556
purine nucleoside metabolic process GO:0042278 241 0.544
regulation of protein kinase activity GO:0045859 232 0.540
protein catabolic process GO:0030163 221 0.538
ribonucleoside catabolic process GO:0042454 206 0.538
neural precursor cell proliferation GO:0061351 121 0.530
response to reactive oxygen species GO:0000302 56 0.529
ribonucleoside triphosphate metabolic process GO:0009199 220 0.518
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.499
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.494
epithelial cell proliferation GO:0050673 174 0.491
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.479
activation of mapk activity GO:0000187 59 0.454
regulation of cellular ketone metabolic process GO:0010565 66 0.451
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.450
nucleobase containing small molecule metabolic process GO:0055086 352 0.445
regulation of transferase activity GO:0051338 263 0.430
regulation of cellular amino acid metabolic process GO:0006521 5 0.423
autophagy GO:0006914 45 0.380
regulation of hepatocyte proliferation GO:2000345 6 0.379
gland development GO:0048732 330 0.378
small gtpase mediated signal transduction GO:0007264 97 0.376
Rat
cell growth GO:0016049 130 0.367
regulation of kinase activity GO:0043549 249 0.352
modification dependent protein catabolic process GO:0019941 133 0.348
regulation of purine nucleotide metabolic process GO:1900542 169 0.348
amine metabolic process GO:0009308 45 0.347
purine nucleotide metabolic process GO:0006163 302 0.330
regulation of neural precursor cell proliferation GO:2000177 70 0.328
cell fate commitment GO:0045165 210 0.326
positive regulation of protein phosphorylation GO:0001934 242 0.318
peptidyl amino acid modification GO:0018193 336 0.295
response to growth factor GO:0070848 198 0.286
dendrite development GO:0016358 115 0.286
regulation of ras gtpase activity GO:0032318 88 0.284
positive regulation of cell projection organization GO:0031346 95 0.281
Human
macromolecule catabolic process GO:0009057 281 0.273
positive regulation of protein kinase activity GO:0045860 144 0.269
mapk cascade GO:0000165 281 0.269
negative regulation of fat cell differentiation GO:0045599 36 0.268
positive regulation of cellular catabolic process GO:0031331 148 0.260
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.259
establishment of protein localization to organelle GO:0072594 118 0.248
regulation of cellular catabolic process GO:0031329 242 0.248
regulation of hydrolase activity GO:0051336 246 0.244
peptidyl tyrosine phosphorylation GO:0018108 143 0.243
negative regulation of phosphate metabolic process GO:0045936 184 0.241
intracellular protein transport GO:0006886 204 0.231
cellular protein catabolic process GO:0044257 155 0.227
response to transforming growth factor beta GO:0071559 88 0.224
regulation of mammary gland epithelial cell proliferation GO:0033599 12 0.223
response to organonitrogen compound GO:0010243 246 0.222
negative regulation of cell proliferation GO:0008285 296 0.221
muscle cell differentiation GO:0042692 261 0.220
positive regulation of cellular amine metabolic process GO:0033240 5 0.219
negative regulation of molecular function GO:0044092 258 0.219
negative regulation of hepatocyte proliferation GO:2000346 3 0.215
positive regulation of nucleoside metabolic process GO:0045979 91 0.214
protein targeting GO:0006605 143 0.214
peptidyl tyrosine modification GO:0018212 145 0.209
cellular amino acid metabolic process GO:0006520 103 0.207
regulation of ras protein signal transduction GO:0046578 114 0.206
fat cell differentiation GO:0045444 160 0.203
protein localization to organelle GO:0033365 185 0.199
regulation of map kinase activity GO:0043405 120 0.195
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.195
regulation of fat cell differentiation GO:0045598 81 0.195
regulation of cellular amine metabolic process GO:0033238 20 0.193
establishment or maintenance of cell polarity GO:0007163 86 0.192
regulation of neuron differentiation GO:0045664 281 0.190
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.186
regulation of microtubule based process GO:0032886 52 0.185
forebrain development GO:0030900 302 0.184
mammary gland epithelium development GO:0061180 65 0.181
negative regulation of epithelial cell proliferation GO:0050680 64 0.176
protein autophosphorylation GO:0046777 61 0.174
positive regulation of mapk cascade GO:0043410 170 0.173
positive regulation of map kinase activity GO:0043406 84 0.169
negative regulation of cellular component organization GO:0051129 194 0.168
positive regulation of hydrolase activity GO:0051345 148 0.167
negative regulation of protein modification process GO:0031400 163 0.162
cellular macromolecule catabolic process GO:0044265 206 0.160
g protein coupled receptor signaling pathway GO:0007186 243 0.159
cellular response to growth factor stimulus GO:0071363 197 0.157
protein import into nucleus GO:0006606 95 0.156
jak stat cascade GO:0007259 42 0.156
regulation of protein binding GO:0043393 60 0.155
neuron projection extension GO:1990138 64 0.154
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.151
regulation of exit from mitosis GO:0007096 1 0.148
regulation of myotube differentiation GO:0010830 62 0.146
cell adhesion GO:0007155 329 0.146
Human
synaptic transmission GO:0007268 329 0.145
Fly
developmental maturation GO:0021700 193 0.145
regulation of mapk cascade GO:0043408 248 0.144
positive regulation of protein catabolic process GO:0045732 60 0.141
morphogenesis of embryonic epithelium GO:0016331 159 0.140
protein modification by small protein conjugation GO:0032446 187 0.138
negative regulation of transferase activity GO:0051348 85 0.136
exocytosis GO:0006887 121 0.135
developmental growth involved in morphogenesis GO:0060560 138 0.135
syncytium formation GO:0006949 43 0.131
regulation of organelle organization GO:0033043 289 0.130
cell matrix adhesion GO:0007160 68 0.127
Human
cytoplasmic transport GO:0016482 234 0.126
positive regulation of proteolysis GO:0045862 85 0.125
positive regulation of protein modification process GO:0031401 299 0.125
microtubule based process GO:0007017 236 0.125
negative regulation of protein phosphorylation GO:0001933 126 0.124
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.123
liver morphogenesis GO:0072576 8 0.122
regulation of cytoskeleton organization GO:0051493 122 0.122
single organism nuclear import GO:1902593 95 0.122
negative regulation of cellular amine metabolic process GO:0033239 1 0.119
regulation of rho protein signal transduction GO:0035023 71 0.119
cellular ketone metabolic process GO:0042180 84 0.113
mammary gland epithelial cell proliferation GO:0033598 24 0.113
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.112
Human
regulation of membrane potential GO:0042391 192 0.112
regulation of organ morphogenesis GO:2000027 144 0.110
epithelial tube morphogenesis GO:0060562 303 0.109
t cell activation GO:0042110 289 0.109
negative regulation of phosphorylation GO:0042326 166 0.107
nuclear transport GO:0051169 139 0.107
multicellular organismal response to stress GO:0033555 62 0.103
regulation of ion homeostasis GO:2000021 64 0.102
positive regulation of protein export from nucleus GO:0046827 4 0.102
positive regulation of kinase activity GO:0033674 155 0.100
regulation of cell motility GO:2000145 236 0.100
Human
synapse organization GO:0050808 125 0.099
Fly
chemotaxis GO:0006935 247 0.099
anatomical structure homeostasis GO:0060249 145 0.098
organelle assembly GO:0070925 177 0.098
protein ubiquitination GO:0016567 171 0.097
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.097
response to peptide hormone GO:0043434 127 0.093
cell substrate adhesion GO:0031589 130 0.092
Human
regulation of binding GO:0051098 111 0.091
rho protein signal transduction GO:0007266 32 0.090
cellular amine metabolic process GO:0044106 44 0.090
regulation of proteolysis GO:0030162 164 0.090
negative regulation of protein metabolic process GO:0051248 282 0.090
syncytium formation by plasma membrane fusion GO:0000768 42 0.090
immune response regulating signaling pathway GO:0002764 125 0.089
substrate adhesion dependent cell spreading GO:0034446 30 0.089
Human
hepaticobiliary system development GO:0061008 67 0.087
regulation of jak stat cascade GO:0046425 34 0.087
jnk cascade GO:0007254 72 0.087
branching morphogenesis of an epithelial tube GO:0048754 159 0.086
stress activated mapk cascade GO:0051403 80 0.084
osteoclast differentiation GO:0030316 62 0.084
regulation of cell projection organization GO:0031344 206 0.083
Human
positive regulation of cellular protein catabolic process GO:1903364 34 0.081
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.080
positive regulation of transferase activity GO:0051347 167 0.080
single organismal cell cell adhesion GO:0016337 131 0.080
regulation of neuron death GO:1901214 134 0.080
positive regulation of cell development GO:0010720 237 0.078
Human
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 17 0.078
positive regulation of mammary gland epithelial cell proliferation GO:0033601 5 0.077
cellular response to peptide hormone stimulus GO:0071375 92 0.077
cellular response to peptide GO:1901653 92 0.077
regulation of exocytosis GO:0017157 61 0.077
negative regulation of phosphorus metabolic process GO:0010563 184 0.077
regulation of anatomical structure size GO:0090066 178 0.076
olfactory bulb development GO:0021772 30 0.076
morphogenesis of a branching epithelium GO:0061138 193 0.076
maintenance of location GO:0051235 89 0.075
liver development GO:0001889 66 0.075
positive regulation of neuron projection development GO:0010976 79 0.074
regulation of actin filament based process GO:0032970 99 0.074
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.073
regulation of secretion GO:0051046 274 0.073
regulation of defense response GO:0031347 233 0.072
olfactory lobe development GO:0021988 32 0.071
camera type eye development GO:0043010 266 0.071
negative regulation of cellular protein metabolic process GO:0032269 247 0.070
negative regulation of hydrolase activity GO:0051346 71 0.069
positive regulation of binding GO:0051099 49 0.069
positive regulation of nucleotide metabolic process GO:0045981 114 0.068
axonogenesis GO:0007409 274 0.068
activation of immune response GO:0002253 138 0.068
positive regulation of integrin mediated signaling pathway GO:2001046 5 0.067
telencephalon cell migration GO:0022029 55 0.067
response to pain GO:0048265 26 0.067
peptidyl threonine modification GO:0018210 31 0.066
membrane organization GO:0061024 245 0.066
mitotic cell cycle process GO:1903047 159 0.065
terminal button organization GO:0072553 3 0.065
stress activated protein kinase signaling cascade GO:0031098 81 0.065
nucleocytoplasmic transport GO:0006913 139 0.065
regulation of striated muscle cell differentiation GO:0051153 81 0.065
neuron projection guidance GO:0097485 141 0.064
regulation of neuron projection development GO:0010975 169 0.064
regulation of cell migration GO:0030334 219 0.064
Human
regulation of actin cytoskeleton organization GO:0032956 84 0.064
cellular response to hormone stimulus GO:0032870 150 0.063
reactive oxygen species metabolic process GO:0072593 84 0.063
intracellular distribution of mitochondria GO:0048312 1 0.063
cell division GO:0051301 120 0.062
leukocyte differentiation GO:0002521 342 0.062
activation of mapkkk activity GO:0000185 1 0.062
axon guidance GO:0007411 141 0.062
neuron migration GO:0001764 122 0.061
multicellular organismal homeostasis GO:0048871 164 0.061
protein import into nucleus translocation GO:0000060 12 0.060
regulation of endocytosis GO:0030100 69 0.059
regulation of terminal button organization GO:2000331 1 0.059
cell maturation GO:0048469 127 0.059
nuclear import GO:0051170 95 0.059
sensory organ morphogenesis GO:0090596 242 0.059
cell cell junction organization GO:0045216 72 0.058
Human
negative regulation of purine nucleotide catabolic process GO:0033122 9 0.058
appendage morphogenesis GO:0035107 149 0.058
mammary gland lobule development GO:0061377 22 0.058
actomyosin structure organization GO:0031032 56 0.057
protein maturation GO:0051604 176 0.057
nuclear division GO:0000280 158 0.057
regulation of protein serine threonine kinase activity GO:0071900 157 0.057
neuron death GO:0070997 154 0.057
positive regulation of protein binding GO:0032092 29 0.056
circulatory system process GO:0003013 197 0.056
establishment of organelle localization GO:0051656 122 0.056
myeloid leukocyte differentiation GO:0002573 119 0.056
regulation of cellular response to stress GO:0080135 159 0.055
regulation of protein transport GO:0051223 163 0.055
dephosphorylation GO:0016311 129 0.054
mammary gland alveolus development GO:0060749 22 0.054
spermatogenesis GO:0007283 284 0.054
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.054
cellular response to organonitrogen compound GO:0071417 145 0.054
neuron maturation GO:0042551 29 0.053
regulation of multi organism process GO:0043900 111 0.053
cellular protein complex assembly GO:0043623 116 0.053
spindle localization GO:0051653 22 0.052
cellular metal ion homeostasis GO:0006875 151 0.052
meiotic cell cycle process GO:1903046 77 0.052
microtubule cytoskeleton organization GO:0000226 157 0.052
telencephalon development GO:0021537 186 0.052
protein import GO:0017038 101 0.052
positive regulation of rac gtpase activity GO:0032855 14 0.051
phagocytosis GO:0006909 66 0.051
neuroblast proliferation GO:0007405 49 0.051
regulation of protein complex assembly GO:0043254 83 0.051
leukocyte proliferation GO:0070661 172 0.051
positive regulation of cell death GO:0010942 224 0.050
Human
epithelial cell proliferation involved in liver morphogenesis GO:0072575 7 0.050
protein modification by small protein conjugation or removal GO:0070647 207 0.050
focal adhesion assembly GO:0048041 19 0.050
Human
muscle cell development GO:0055001 133 0.050
cell junction organization GO:0034330 77 0.050
Human
retina morphogenesis in camera type eye GO:0060042 45 0.050
negative regulation of peroxidase activity GO:2000469 1 0.049
response to peptide GO:1901652 136 0.049
t cell proliferation GO:0042098 120 0.049
asymmetric stem cell division GO:0098722 3 0.049
forebrain cell migration GO:0021885 58 0.049
regulation of cellular component biogenesis GO:0044087 181 0.049
ossification GO:0001503 216 0.049
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.049
positive regulation of cell motility GO:2000147 116 0.048
Human
positive regulation of ras gtpase activity GO:0032320 65 0.048
regulation of secretion by cell GO:1903530 249 0.048
locomotory behavior GO:0007626 195 0.047
negative regulation of kinase activity GO:0033673 81 0.047
regulation of vesicle mediated transport GO:0060627 139 0.046
negative regulation of cellular catabolic process GO:0031330 47 0.046
protein localization to plasma membrane GO:0072659 57 0.046
cellular response to growth hormone stimulus GO:0071378 7 0.045
protein processing GO:0016485 163 0.045
regulation of nuclear division GO:0051783 56 0.044
regulation of cellular component size GO:0032535 121 0.044
positive regulation of organelle organization GO:0010638 128 0.043
actin filament polymerization GO:0030041 44 0.043
membrane depolarization GO:0051899 64 0.043
endocytosis GO:0006897 168 0.043
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.043
t cell anergy GO:0002870 4 0.042
negative regulation of neural precursor cell proliferation GO:2000178 18 0.042
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.042
regulation of nucleocytoplasmic transport GO:0046822 73 0.042
sequestering of calcium ion GO:0051208 18 0.042
negative regulation of nucleotide catabolic process GO:0030812 9 0.042
skeletal system development GO:0001501 356 0.041
establishment of mitotic spindle localization GO:0040001 12 0.041
organelle localization GO:0051640 179 0.041
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.041
tissue homeostasis GO:0001894 115 0.040
eating behavior GO:0042755 15 0.040
neuron apoptotic process GO:0051402 142 0.040
protein polymerization GO:0051258 57 0.040
negative regulation of cell cycle GO:0045786 123 0.040
regulation of leukocyte differentiation GO:1902105 159 0.040
regulation of synaptic vesicle transport GO:1902803 13 0.040
microtubule based movement GO:0007018 84 0.040
bone resorption GO:0045453 38 0.040
photoreceptor cell differentiation GO:0046530 52 0.039
response to inorganic substance GO:0010035 96 0.039
regulation of metal ion transport GO:0010959 106 0.039
retina development in camera type eye GO:0060041 119 0.038
organelle fission GO:0048285 170 0.038
regulation of cell cycle process GO:0010564 160 0.038
developmental cell growth GO:0048588 84 0.038
muscle tissue development GO:0060537 308 0.038
actin cytoskeleton organization GO:0030036 220 0.038
regulation of protein targeting GO:1903533 61 0.038
engulfment of apoptotic cell GO:0043652 3 0.037
cellular ion homeostasis GO:0006873 165 0.037
transmission of nerve impulse GO:0019226 76 0.037
negative regulation of organelle organization GO:0010639 90 0.037
lymphocyte homeostasis GO:0002260 64 0.037
oocyte axis specification GO:0007309 2 0.037
negative regulation of immune system process GO:0002683 209 0.037
positive regulation of intracellular protein transport GO:0090316 42 0.036
action potential GO:0001508 78 0.036
feeding behavior GO:0007631 62 0.036
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.036
digestive tract development GO:0048565 190 0.036
mitotic nuclear division GO:0007067 48 0.036
regulation of heart contraction GO:0008016 77 0.036
wnt signaling pathway GO:0016055 188 0.036
oocyte construction GO:0007308 2 0.035
asymmetric neuroblast division GO:0055059 1 0.035
germ cell development GO:0007281 185 0.035
exit from mitosis GO:0010458 3 0.035
carbohydrate derivative biosynthetic process GO:1901137 183 0.035
sequestering of metal ion GO:0051238 19 0.034
regulation of protein processing GO:0070613 96 0.034
immune response activating signal transduction GO:0002757 116 0.034
pallium development GO:0021543 120 0.034
regulation of cell cycle GO:0051726 281 0.034
digestive tract morphogenesis GO:0048546 147 0.034
cell junction assembly GO:0034329 52 0.033
Human
regulation of protein catabolic process GO:0042176 108 0.033
neuronal action potential GO:0019228 54 0.033
homeostasis of number of cells GO:0048872 210 0.033
regulation of protein localization GO:0032880 231 0.033
positive regulation of lymphocyte anergy GO:0002913 4 0.033
positive regulation of jak stat cascade GO:0046427 22 0.032
regulation of proteasomal protein catabolic process GO:0061136 46 0.032
sensory perception of umami taste GO:0050917 4 0.032
lymphocyte proliferation GO:0046651 164 0.031
mitochondrion organization GO:0007005 134 0.031
regulation of cellular response to growth factor stimulus GO:0090287 82 0.031
negative regulation of protein maturation GO:1903318 79 0.031
cellular response to inorganic substance GO:0071241 37 0.031
regulation of dendritic spine morphogenesis GO:0061001 17 0.031
purine nucleotide biosynthetic process GO:0006164 65 0.031
negative regulation of protein dephosphorylation GO:0035308 2 0.031
positive regulation of lymphocyte activation GO:0051251 140 0.031
immune effector process GO:0002252 321 0.031
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.031
cartilage development GO:0051216 140 0.030
regulation of synaptic vesicle recycling GO:1903421 2 0.030
axon ensheathment GO:0008366 76 0.030
blood vessel morphogenesis GO:0048514 285 0.030
actin cytoskeleton reorganization GO:0031532 21 0.030
central nervous system neuron differentiation GO:0021953 162 0.030
regulation of lymphocyte anergy GO:0002911 4 0.030
regulation of peroxidase activity GO:2000468 1 0.030
establishment of synaptic vesicle localization GO:0097480 57 0.030
tissue remodeling GO:0048771 102 0.030
regulation of lymphocyte proliferation GO:0050670 117 0.030
negative regulation of intracellular protein transport GO:0090317 27 0.029
positive regulation of apoptotic process GO:0043065 217 0.029
Human
regulation of microtubule cytoskeleton organization GO:0070507 37 0.029
myeloid cell differentiation GO:0030099 233 0.029
apoptotic signaling pathway GO:0097190 306 0.029
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.029
neural retina development GO:0003407 41 0.029
digestive system development GO:0055123 200 0.029
eye photoreceptor cell differentiation GO:0001754 41 0.028
response to catecholamine GO:0071869 4 0.028
organonitrogen compound biosynthetic process GO:1901566 192 0.028
detection of light stimulus GO:0009583 25 0.028
blood circulation GO:0008015 195 0.028
adherens junction organization GO:0034332 28 0.028
Human
regulation of canonical wnt signaling pathway GO:0060828 82 0.028
regulation of t cell proliferation GO:0042129 92 0.028
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.028
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.028
bone remodeling GO:0046849 53 0.028
regulation of cell projection assembly GO:0060491 38 0.028
gastrulation GO:0007369 116 0.027
positive regulation of t cell anergy GO:0002669 4 0.027
regulation of cell growth GO:0001558 91 0.027
cell substrate junction assembly GO:0007044 24 0.027
Human
positive regulation of cellular component biogenesis GO:0044089 94 0.027
regulation of mitosis GO:0007088 29 0.026
regulation of cell activation GO:0050865 289 0.026
adherens junction assembly GO:0034333 22 0.026
Human
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.026
ensheathment of neurons GO:0007272 76 0.026
peptidyl serine modification GO:0018209 83 0.026
cellular lipid metabolic process GO:0044255 323 0.026
leukocyte migration GO:0050900 124 0.026
negative regulation of nucleoside metabolic process GO:0045978 11 0.026
regulation of mitotic cell cycle GO:0007346 126 0.026
regulation of lymphocyte activation GO:0051249 240 0.026
renal system development GO:0072001 225 0.026
actin filament based movement GO:0030048 23 0.026
regulation of ossification GO:0030278 112 0.026
appendage development GO:0048736 166 0.025
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.025
negative regulation of protein complex disassembly GO:0043242 22 0.025
extrinsic apoptotic signaling pathway GO:0097191 126 0.025
cellular response to cytokine stimulus GO:0071345 189 0.025
cellular response to ammonium ion GO:0071242 2 0.025
cerebral cortex development GO:0021987 86 0.025
positive regulation of neuron differentiation GO:0045666 141 0.025
positive regulation of cell growth GO:0030307 33 0.025
regulation of actin filament polymerization GO:0030833 38 0.025
stem cell proliferation GO:0072089 117 0.025
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.025
mitotic cytokinesis GO:0000281 4 0.025
b cell differentiation GO:0030183 78 0.024
hematopoietic progenitor cell differentiation GO:0002244 143 0.024
chromosome segregation GO:0007059 48 0.024
regulation of body fluid levels GO:0050878 162 0.024
multicellular organism growth GO:0035264 161 0.024
regulation of wnt signaling pathway GO:0030111 123 0.024
cellular response to dna damage stimulus GO:0006974 207 0.024
negative regulation of protein processing GO:0010955 79 0.024
epithelial cell development GO:0002064 159 0.024
neurotransmitter secretion GO:0007269 62 0.024
formation of primary germ layer GO:0001704 77 0.024
positive regulation of nervous system development GO:0051962 221 0.024
lymphocyte anergy GO:0002249 4 0.024
divalent metal ion transport GO:0070838 172 0.024
calcium ion homeostasis GO:0055074 127 0.024
limbic system development GO:0021761 72 0.024

Arhgef7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.093
disease of anatomical entity DOID:7 0 0.093
nervous system disease DOID:863 0 0.093
non syndromic intellectual disability DOID:0050889 0 0.056
disease of mental health DOID:150 0 0.056
developmental disorder of mental health DOID:0060037 0 0.056
specific developmental disorder DOID:0060038 0 0.056
intellectual disability DOID:1059 0 0.056
musculoskeletal system disease DOID:17 0 0.038
neurodegenerative disease DOID:1289 0 0.027
myopathy DOID:423 0 0.025
muscular disease DOID:0080000 0 0.025
muscle tissue disease DOID:66 0 0.025