Mus musculus

172 known processes

Arhgef5

Rho guanine nucleotide exchange factor (GEF) 5

(Aliases: AW495314,Tim1,2210412D05Rik,AA717842)

Arhgef5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organismal cell cell adhesion GO:0016337 131 0.293
cell adhesion GO:0007155 329 0.276
actin cytoskeleton organization GO:0030036 220 0.206
synaptic transmission GO:0007268 329 0.160
Mouse
leukocyte differentiation GO:0002521 342 0.147
regulation of membrane potential GO:0042391 192 0.140
regulation of cellular amine metabolic process GO:0033238 20 0.135
extrinsic apoptotic signaling pathway GO:0097191 126 0.126
membrane organization GO:0061024 245 0.123
lymphocyte proliferation GO:0046651 164 0.111
regulation of actin filament based process GO:0032970 99 0.111
regulation of t cell activation GO:0050863 170 0.110
t cell activation GO:0042110 289 0.109
apoptotic signaling pathway GO:0097190 306 0.105
cellular amino acid metabolic process GO:0006520 103 0.102
cellular amine metabolic process GO:0044106 44 0.100
epidermis development GO:0008544 187 0.099
regulation of lymphocyte activation GO:0051249 240 0.098
locomotory behavior GO:0007626 195 0.097
skin development GO:0043588 220 0.097
single organism cell adhesion GO:0098602 156 0.096
cellular ketone metabolic process GO:0042180 84 0.095
regulation of actin cytoskeleton organization GO:0032956 84 0.092
negative regulation of phosphate metabolic process GO:0045936 184 0.089
regulation of organelle organization GO:0033043 289 0.088
ras protein signal transduction GO:0007265 77 0.087
immune effector process GO:0002252 321 0.085
transmembrane transport GO:0055085 412 0.084
regulation of cell activation GO:0050865 289 0.083
cell cell junction organization GO:0045216 72 0.082
regulation of defense response GO:0031347 233 0.081
ion transmembrane transport GO:0034220 361 0.081
leukocyte proliferation GO:0070661 172 0.080
negative regulation of intracellular signal transduction GO:1902532 167 0.079
regulation of system process GO:0044057 200 0.079
amine metabolic process GO:0009308 45 0.079
exocytosis GO:0006887 121 0.078
endocytosis GO:0006897 168 0.078
regulation of cell projection organization GO:0031344 206 0.077
Mouse
regulation of hydrolase activity GO:0051336 246 0.077
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.077
endomembrane system organization GO:0010256 147 0.076
regulation of protein localization GO:0032880 231 0.073
negative regulation of lymphocyte activation GO:0051250 91 0.072
axonogenesis GO:0007409 274 0.069
regulation of cellular amino acid metabolic process GO:0006521 5 0.069
regulation of lymphocyte proliferation GO:0050670 117 0.068
muscle system process GO:0003012 141 0.068
lymphocyte differentiation GO:0030098 242 0.067
cytokine production GO:0001816 319 0.067
cation transport GO:0006812 399 0.067
cell junction organization GO:0034330 77 0.066
regulation of cellular ketone metabolic process GO:0010565 66 0.065
synapse organization GO:0050808 125 0.065
Mouse
muscle cell differentiation GO:0042692 261 0.064
regulation of cytoskeleton organization GO:0051493 122 0.064
regulation of cell migration GO:0030334 219 0.064
adult behavior GO:0030534 135 0.062
negative regulation of immune system process GO:0002683 209 0.061
chemotaxis GO:0006935 247 0.060
actin filament organization GO:0007015 113 0.059
cytokine mediated signaling pathway GO:0019221 115 0.059
small gtpase mediated signal transduction GO:0007264 97 0.058
muscle tissue development GO:0060537 308 0.056
regulation of synaptic plasticity GO:0048167 87 0.056
regulation of t cell proliferation GO:0042129 92 0.055
regulation of mapk cascade GO:0043408 248 0.054
mitotic cell cycle process GO:1903047 159 0.054
regulation of leukocyte proliferation GO:0070663 121 0.053
purine nucleotide catabolic process GO:0006195 211 0.053
action potential GO:0001508 78 0.052
response to light stimulus GO:0009416 135 0.051
positive regulation of protein modification process GO:0031401 299 0.051
regulation of ion transport GO:0043269 215 0.051
embryonic organ morphogenesis GO:0048562 276 0.050
positive regulation of cellular amine metabolic process GO:0033240 5 0.050
negative regulation of cell proliferation GO:0008285 296 0.050
organelle localization GO:0051640 179 0.049
i kappab kinase nf kappab signaling GO:0007249 85 0.049
dendrite development GO:0016358 115 0.049
Mouse
t cell differentiation GO:0030217 174 0.048
multicellular organismal signaling GO:0035637 91 0.048
cognition GO:0050890 149 0.047
actin polymerization or depolymerization GO:0008154 54 0.047
protein localization to membrane GO:0072657 108 0.047
regulation of lymphocyte differentiation GO:0045619 107 0.047
cell cell adhesion GO:0098609 41 0.047
keratinocyte differentiation GO:0030216 48 0.046
regulation of actin filament length GO:0030832 45 0.046
purine ribonucleotide catabolic process GO:0009154 208 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.045
leukocyte mediated immunity GO:0002443 174 0.045
regulation of transferase activity GO:0051338 263 0.045
dephosphorylation GO:0016311 129 0.044
negative regulation of cell activation GO:0050866 111 0.044
cellular nitrogen compound catabolic process GO:0044270 280 0.044
urogenital system development GO:0001655 261 0.044
cell type specific apoptotic process GO:0097285 268 0.044
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.044
Mouse
muscle cell development GO:0055001 133 0.044
positive regulation of cell activation GO:0050867 158 0.043
purine containing compound metabolic process GO:0072521 311 0.043
striated muscle tissue development GO:0014706 293 0.043
adult locomotory behavior GO:0008344 91 0.042
regulation of cell motility GO:2000145 236 0.042
regulation of leukocyte differentiation GO:1902105 159 0.042
intracellular protein transport GO:0006886 204 0.041
negative regulation of molecular function GO:0044092 258 0.041
adaptive immune response GO:0002250 155 0.041
positive regulation of secretion by cell GO:1903532 114 0.041
purine nucleoside triphosphate metabolic process GO:0009144 226 0.040
t cell proliferation GO:0042098 120 0.040
regulation of secretion by cell GO:1903530 249 0.040
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.040
regulation of secretion GO:0051046 274 0.040
regulation of cellular component biogenesis GO:0044087 181 0.039
cellular component assembly involved in morphogenesis GO:0010927 139 0.039
positive regulation of secretion GO:0051047 130 0.039
sensory perception GO:0007600 245 0.039
homeostasis of number of cells GO:0048872 210 0.039
response to radiation GO:0009314 165 0.038
negative regulation of phosphorus metabolic process GO:0010563 184 0.038
microtubule cytoskeleton organization GO:0000226 157 0.038
regulation of apoptotic signaling pathway GO:2001233 197 0.038
cellular response to cytokine stimulus GO:0071345 189 0.038
cytoplasmic transport GO:0016482 234 0.038
cation homeostasis GO:0055080 212 0.038
establishment of organelle localization GO:0051656 122 0.038
glycosyl compound catabolic process GO:1901658 206 0.037
learning or memory GO:0007611 148 0.037
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
muscle contraction GO:0006936 101 0.037
negative regulation of t cell activation GO:0050868 65 0.037
multicellular organismal homeostasis GO:0048871 164 0.036
regulation of cell adhesion GO:0030155 154 0.036
positive regulation of cellular component biogenesis GO:0044089 94 0.036
regulation of neuron differentiation GO:0045664 281 0.036
Mouse
intermediate filament cytoskeleton organization GO:0045104 26 0.035
striated muscle cell development GO:0055002 125 0.035
leukocyte activation involved in immune response GO:0002366 126 0.035
neuronal action potential GO:0019228 54 0.035
inter male aggressive behavior GO:0002121 3 0.035
negative regulation of leukocyte differentiation GO:1902106 51 0.035
regulation of response to wounding GO:1903034 189 0.034
ribonucleotide metabolic process GO:0009259 291 0.034
spermatogenesis GO:0007283 284 0.034
negative regulation of phosphorylation GO:0042326 166 0.034
protein localization to cell junction GO:1902414 3 0.034
response to growth factor GO:0070848 198 0.034
cellular homeostasis GO:0019725 240 0.033
nucleoside phosphate metabolic process GO:0006753 338 0.033
inflammatory response GO:0006954 244 0.033
placenta development GO:0001890 140 0.033
developmental maturation GO:0021700 193 0.033
Mouse
mitotic cell cycle GO:0000278 195 0.032
cell junction assembly GO:0034329 52 0.032
establishment of vesicle localization GO:0051650 81 0.032
epithelial tube morphogenesis GO:0060562 303 0.032
activation of immune response GO:0002253 138 0.032
purine ribonucleoside metabolic process GO:0046128 241 0.032
regulation of nucleoside metabolic process GO:0009118 130 0.032
regulation of t cell differentiation GO:0045580 83 0.032
positive regulation of ion transport GO:0043270 65 0.032
myeloid cell differentiation GO:0030099 233 0.032
cell activation involved in immune response GO:0002263 126 0.032
wnt signaling pathway GO:0016055 188 0.031
glial cell differentiation GO:0010001 131 0.031
cellular ion homeostasis GO:0006873 165 0.031
nucleoside metabolic process GO:0009116 246 0.031
intermediate filament based process GO:0045103 27 0.030
leukocyte migration GO:0050900 124 0.030
protein maturation GO:0051604 176 0.030
epithelial cell development GO:0002064 159 0.030
respiratory tube development GO:0030323 167 0.030
regulation of neuron projection development GO:0010975 169 0.030
Mouse
regulation of postsynaptic membrane potential GO:0060078 48 0.029
regulation of protein complex assembly GO:0043254 83 0.029
striated muscle contraction GO:0006941 45 0.029
cell matrix adhesion GO:0007160 68 0.029
actin filament bundle assembly GO:0051017 40 0.029
organic anion transport GO:0015711 137 0.029
cell growth GO:0016049 130 0.029
t cell differentiation in thymus GO:0033077 77 0.029
kidney development GO:0001822 213 0.029
mapk cascade GO:0000165 281 0.028
protein targeting GO:0006605 143 0.028
gland development GO:0048732 330 0.028
ventricular cardiac muscle cell action potential GO:0086005 4 0.028
plasma membrane organization GO:0007009 90 0.028
myeloid leukocyte differentiation GO:0002573 119 0.028
cellular protein complex assembly GO:0043623 116 0.028
epithelial cell proliferation GO:0050673 174 0.028
positive regulation of mapk cascade GO:0043410 170 0.028
protein localization to adherens junction GO:0071896 2 0.028
positive regulation of apoptotic process GO:0043065 217 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
ribonucleoside metabolic process GO:0009119 245 0.028
divalent inorganic cation transport GO:0072511 178 0.028
organophosphate catabolic process GO:0046434 232 0.028
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.028
calcium ion transport GO:0006816 159 0.027
actin filament based movement GO:0030048 23 0.027
vesicle localization GO:0051648 86 0.027
b cell activation GO:0042113 161 0.027
cell substrate adhesion GO:0031589 130 0.027
purine nucleoside metabolic process GO:0042278 241 0.027
ossification GO:0001503 216 0.027
purine ribonucleotide metabolic process GO:0009150 290 0.027
neuron neuron synaptic transmission GO:0007270 69 0.027
anion transport GO:0006820 177 0.027
negative regulation of apoptotic signaling pathway GO:2001234 104 0.027
b cell proliferation GO:0042100 53 0.027
protein localization to plasma membrane GO:0072659 57 0.027
divalent metal ion transport GO:0070838 172 0.027
sensory organ morphogenesis GO:0090596 242 0.026
positive regulation of protein phosphorylation GO:0001934 242 0.026
ribonucleoside triphosphate metabolic process GO:0009199 220 0.026
neuron projection guidance GO:0097485 141 0.026
rhythmic process GO:0048511 174 0.026
forebrain development GO:0030900 302 0.026
regulation of muscle system process GO:0090257 80 0.026
interspecies interaction between organisms GO:0044419 83 0.026
respiratory system development GO:0060541 190 0.026
negative regulation of defense response GO:0031348 77 0.026
cytokine metabolic process GO:0042107 71 0.026
regulation of anatomical structure size GO:0090066 178 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
peptidyl tyrosine modification GO:0018212 145 0.025
carboxylic acid transport GO:0046942 100 0.025
inorganic cation transmembrane transport GO:0098662 207 0.025
developmental growth involved in morphogenesis GO:0060560 138 0.025
cellular response to growth factor stimulus GO:0071363 197 0.025
actin filament polymerization GO:0030041 44 0.025
peptidyl amino acid modification GO:0018193 336 0.025
lymphocyte mediated immunity GO:0002449 139 0.025
organelle assembly GO:0070925 177 0.025
chromatin organization GO:0006325 206 0.025
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.025
microtubule based process GO:0007017 236 0.025
vesicle organization GO:0016050 60 0.025
regulation of establishment of protein localization GO:0070201 181 0.025
blood vessel morphogenesis GO:0048514 285 0.024
cellular divalent inorganic cation homeostasis GO:0072503 127 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.024
compound eye development GO:0048749 1 0.024
positive regulation of lymphocyte activation GO:0051251 140 0.024
nucleotide catabolic process GO:0009166 217 0.024
stem cell differentiation GO:0048863 268 0.024
cytokine biosynthetic process GO:0042089 68 0.024
protein modification by small protein conjugation GO:0032446 187 0.024
regulation of homeostatic process GO:0032844 182 0.024
nucleoside triphosphate catabolic process GO:0009143 205 0.023
embryonic placenta development GO:0001892 98 0.023
regulation of purine nucleotide catabolic process GO:0033121 122 0.023
nucleoside catabolic process GO:0009164 206 0.023
positive regulation of nervous system development GO:0051962 221 0.023
learning GO:0007612 98 0.023
myeloid leukocyte activation GO:0002274 83 0.023
negative regulation of cellular amine metabolic process GO:0033239 1 0.023
rac protein signal transduction GO:0016601 13 0.023
regulation of actin polymerization or depolymerization GO:0008064 45 0.023
desmosome organization GO:0002934 5 0.023
dna metabolic process GO:0006259 303 0.022
ribonucleotide catabolic process GO:0009261 208 0.022
protein oligomerization GO:0051259 67 0.022
lipid transport GO:0006869 98 0.022
transmission of nerve impulse GO:0019226 76 0.022
regulation of cytokine production GO:0001817 266 0.022
macromolecule catabolic process GO:0009057 281 0.022
positive regulation of cell adhesion GO:0045785 80 0.022
regulation of exocytosis GO:0017157 61 0.022
germ cell development GO:0007281 185 0.022
male gamete generation GO:0048232 285 0.022
response to acid chemical GO:0001101 111 0.022
intermediate filament organization GO:0045109 15 0.022
nucleotide metabolic process GO:0009117 332 0.022
regulation of vesicle mediated transport GO:0060627 139 0.022
morphogenesis of a branching structure GO:0001763 203 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
blood circulation GO:0008015 195 0.022
nitrogen compound transport GO:0071705 271 0.022
regionalization GO:0003002 337 0.021
innate immune response GO:0045087 157 0.021
regulation of kinase activity GO:0043549 249 0.021
camera type eye development GO:0043010 266 0.021
Mouse
membrane hyperpolarization GO:0060081 21 0.021
morphogenesis of embryonic epithelium GO:0016331 159 0.021
positive regulation of organelle organization GO:0010638 128 0.021
regulation of nucleotide catabolic process GO:0030811 122 0.021
phospholipid metabolic process GO:0006644 87 0.021
spermatid development GO:0007286 108 0.021
intrinsic apoptotic signaling pathway GO:0097193 132 0.021
positive regulation of cell migration GO:0030335 109 0.021
cellular chemical homeostasis GO:0055082 215 0.021
regulation of actin filament polymerization GO:0030833 38 0.021
regulation of cell projection assembly GO:0060491 38 0.021
negative regulation of protein modification process GO:0031400 163 0.021
cellular metal ion homeostasis GO:0006875 151 0.021
regulation of nucleotide metabolic process GO:0006140 169 0.021
organelle fission GO:0048285 170 0.021
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.020
membrane depolarization GO:0051899 64 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
Mouse
skeletal muscle organ development GO:0060538 163 0.020
positive regulation of cell motility GO:2000147 116 0.020
synaptic vesicle transport GO:0048489 57 0.020
negative regulation of cytokine production GO:0001818 84 0.020
regulation of multi organism process GO:0043900 111 0.020
rho protein signal transduction GO:0007266 32 0.020
viral process GO:0016032 41 0.020
protein localization to organelle GO:0033365 185 0.020
mitotic cytokinesis GO:0000281 4 0.020
regulation of cellular component size GO:0032535 121 0.020
response to lipopolysaccharide GO:0032496 128 0.020
immune response regulating signaling pathway GO:0002764 125 0.020
metal ion homeostasis GO:0055065 189 0.020
cell fate commitment GO:0045165 210 0.020
protein catabolic process GO:0030163 221 0.020
kidney epithelium development GO:0072073 121 0.019
spermatid differentiation GO:0048515 115 0.019
protein polymerization GO:0051258 57 0.019
synaptic vesicle localization GO:0097479 59 0.019
localization within membrane GO:0051668 4 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
alpha beta t cell differentiation GO:0046632 69 0.019
organic acid transport GO:0015849 101 0.019
response to amino acid GO:0043200 37 0.019
regulation of cell cycle GO:0051726 281 0.019
peptidyl tyrosine phosphorylation GO:0018108 143 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.019
negative regulation of response to wounding GO:1903035 77 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
establishment of synaptic vesicle localization GO:0097480 57 0.019
maintenance of presynaptic active zone structure GO:0048790 1 0.019
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 20 0.019
regulation of heart rate GO:0002027 36 0.018
chromatin modification GO:0016568 187 0.018
myeloid cell homeostasis GO:0002262 114 0.018
photoreceptor cell differentiation GO:0046530 52 0.018
defense response to bacterium GO:0042742 119 0.018
oocyte axis specification GO:0007309 2 0.018
regulation of alpha beta t cell activation GO:0046634 53 0.018
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.018
cell chemotaxis GO:0060326 81 0.018
social behavior GO:0035176 21 0.018
response to molecule of bacterial origin GO:0002237 143 0.018
leukocyte homeostasis GO:0001776 79 0.018
development of primary sexual characteristics GO:0045137 143 0.018
nuclear transport GO:0051169 139 0.018
cation transmembrane transport GO:0098655 266 0.018
regulation of synaptic transmission gabaergic GO:0032228 17 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
gliogenesis GO:0042063 141 0.018
regulation of intracellular transport GO:0032386 159 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
multi organism behavior GO:0051705 62 0.018
circulatory system process GO:0003013 197 0.018
nucleoside monophosphate metabolic process GO:0009123 85 0.018
actin mediated cell contraction GO:0070252 15 0.018
establishment of protein localization to membrane GO:0090150 54 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
heart contraction GO:0060047 93 0.017
protein homooligomerization GO:0051260 43 0.017
renal system development GO:0072001 225 0.017
telencephalon development GO:0021537 186 0.017
alpha beta t cell activation GO:0046631 91 0.017
extracellular structure organization GO:0043062 148 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
regulation of hippo signaling GO:0035330 1 0.017
regulation of epithelial cell proliferation GO:0050678 141 0.017
oocyte construction GO:0007308 2 0.017
fat cell differentiation GO:0045444 160 0.017
positive regulation of cell death GO:0010942 224 0.017
cell recognition GO:0008037 83 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
neuron death GO:0070997 154 0.017
nephron development GO:0072006 109 0.016
response to organonitrogen compound GO:0010243 246 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
neurotransmitter transport GO:0006836 76 0.016
positive regulation of leukocyte differentiation GO:1902107 86 0.016
protein localization to nucleus GO:0034504 121 0.016
regulation of metal ion transport GO:0010959 106 0.016
heart process GO:0003015 94 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
regulation of b cell activation GO:0050864 81 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
actomyosin structure organization GO:0031032 56 0.016
receptor mediated endocytosis GO:0006898 51 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
cardiac muscle cell contraction GO:0086003 7 0.016
adherens junction organization GO:0034332 28 0.016
stem cell proliferation GO:0072089 117 0.016
ear development GO:0043583 200 0.016
sensory perception of pain GO:0019233 47 0.016
negative regulation of transferase activity GO:0051348 85 0.016
adherens junction assembly GO:0034333 22 0.016
positive regulation of cell development GO:0010720 237 0.016
ensheathment of neurons GO:0007272 76 0.016
lymphocyte activation involved in immune response GO:0002285 93 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
renal system process GO:0003014 48 0.016
positive regulation of t cell activation GO:0050870 101 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
developmental cell growth GO:0048588 84 0.016
negative regulation of lymphocyte proliferation GO:0050672 45 0.016
sequestering of calcium ion GO:0051208 18 0.016
methylation GO:0032259 134 0.016
negative regulation of cytoskeleton organization GO:0051494 36 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
regulation of adaptive immune response GO:0002819 90 0.015
macromolecule methylation GO:0043414 120 0.015
regulation of neurotransmitter levels GO:0001505 87 0.015
substrate dependent cell migration GO:0006929 18 0.015
t cell mediated immunity GO:0002456 50 0.015
ear morphogenesis GO:0042471 118 0.015
regulation of proteolysis GO:0030162 164 0.015
negative regulation of kinase activity GO:0033673 81 0.015
positive regulation of membrane potential GO:0045838 15 0.015
positive regulation of cytokine production GO:0001819 174 0.015
sensory perception of sound GO:0007605 97 0.015
organophosphate biosynthetic process GO:0090407 122 0.015
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.015
positive regulation of innate immune response GO:0045089 80 0.015
establishment of protein localization to plasma membrane GO:0090002 34 0.015
skeletal system development GO:0001501 356 0.015
lung development GO:0030324 164 0.015
myosin filament assembly GO:0031034 2 0.015
lateral inhibition GO:0046331 1 0.015
positive regulation of defense response GO:0031349 124 0.015
regulation of b cell proliferation GO:0030888 39 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
purine containing compound catabolic process GO:0072523 213 0.015
neuromuscular process GO:0050905 99 0.015
wound healing GO:0042060 157 0.015
Mouse
atp metabolic process GO:0046034 75 0.015
nuclear division GO:0000280 158 0.015
tissue homeostasis GO:0001894 115 0.015
response to oxygen levels GO:0070482 62 0.015
regulation of transmembrane transport GO:0034762 128 0.014
heterocycle catabolic process GO:0046700 280 0.014
striated muscle myosin thick filament assembly GO:0071688 1 0.014
negative regulation of wnt signaling pathway GO:0030178 73 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.014
oocyte anterior posterior axis specification GO:0007314 2 0.014
regulation of ion transmembrane transport GO:0034765 119 0.014
cellularization GO:0007349 1 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
circadian rhythm GO:0007623 114 0.014
lamellipodium organization GO:0097581 29 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.014
Mouse
nephron epithelium development GO:0072009 92 0.014
negative regulation of epithelial cell proliferation GO:0050680 64 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
response to water GO:0009415 1 0.014
synaptic transmission gabaergic GO:0051932 19 0.014
defense response to other organism GO:0098542 197 0.014
cd4 positive alpha beta t cell activation GO:0035710 45 0.014
nuclear import GO:0051170 95 0.014
regulation of interleukin 8 production GO:0032677 3 0.014
rna interference GO:0016246 2 0.014
carbohydrate homeostasis GO:0033500 128 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.014
response to epidermal growth factor GO:0070849 4 0.013
myotube differentiation GO:0014902 105 0.013
dendritic spine maintenance GO:0097062 4 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
negative regulation of leukocyte proliferation GO:0070664 46 0.013

Arhgef5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.195
disease of anatomical entity DOID:7 0 0.195
musculoskeletal system disease DOID:17 0 0.195
myopathy DOID:423 0 0.126
heart disease DOID:114 0 0.126
cardiomyopathy DOID:0050700 0 0.126
cardiovascular system disease DOID:1287 0 0.126
muscle tissue disease DOID:66 0 0.126
nervous system disease DOID:863 0 0.061
intrinsic cardiomyopathy DOID:0060036 0 0.050
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 0 0.045
cancer DOID:162 0 0.033
disease of cellular proliferation DOID:14566 0 0.033
organ system cancer DOID:0050686 0 0.033
sensory system disease DOID:0050155 0 0.026
neuropathy DOID:870 0 0.021
neuromuscular disease DOID:440 0 0.017
charcot marie tooth disease DOID:10595 0 0.017
immune system disease DOID:2914 0 0.016