Mus musculus

0 known processes

Prrc2a

proline-rich coiled-coil 2A

(Aliases: G2,Wbp12,D17H6S51E,mKIAA4178,3110039B05Rik,Bat2,Bat-2,KIAA4178)

Prrc2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spermatogenesis GO:0007283 284 0.186
male gamete generation GO:0048232 285 0.114
regulation of cellular ketone metabolic process GO:0010565 66 0.098
negative regulation of cellular protein metabolic process GO:0032269 247 0.094
meiotic cell cycle GO:0051321 122 0.085
microtubule based process GO:0007017 236 0.075
cilium morphogenesis GO:0060271 102 0.073
regionalization GO:0003002 337 0.064
regulation of protein kinase activity GO:0045859 232 0.059
positive regulation of protein kinase activity GO:0045860 144 0.059
positive regulation of protein phosphorylation GO:0001934 242 0.057
gonad development GO:0008406 141 0.056
cellular ketone metabolic process GO:0042180 84 0.055
regulation of transferase activity GO:0051338 263 0.053
germ cell development GO:0007281 185 0.052
regulation of gtp catabolic process GO:0033124 113 0.051
purine containing compound metabolic process GO:0072521 311 0.051
stem cell differentiation GO:0048863 268 0.051
positive regulation of cellular amine metabolic process GO:0033240 5 0.050
heterocycle catabolic process GO:0046700 280 0.049
guanosine containing compound catabolic process GO:1901069 144 0.048
regulation of cell cycle GO:0051726 281 0.048
positive regulation of kinase activity GO:0033674 155 0.048
positive regulation of transferase activity GO:0051347 167 0.047
regulation of cellular amino acid metabolic process GO:0006521 5 0.047
regulation of kinase activity GO:0043549 249 0.046
peptidyl amino acid modification GO:0018193 336 0.045
regulation of cellular amine metabolic process GO:0033238 20 0.045
negative regulation of protein modification process GO:0031400 163 0.045
nucleoside metabolic process GO:0009116 246 0.044
chromatin organization GO:0006325 206 0.044
cellular amine metabolic process GO:0044106 44 0.044
rho protein signal transduction GO:0007266 32 0.043
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
microtubule cytoskeleton organization GO:0000226 157 0.043
organelle fission GO:0048285 170 0.041
endocytosis GO:0006897 168 0.040
actin cytoskeleton organization GO:0030036 220 0.039
negative regulation of protein metabolic process GO:0051248 282 0.039
meiotic nuclear division GO:0007126 115 0.039
nuclear division GO:0000280 158 0.039
purine nucleoside metabolic process GO:0042278 241 0.039
regulation of vesicle mediated transport GO:0060627 139 0.038
positive regulation of protein modification process GO:0031401 299 0.038
regulation of protein serine threonine kinase activity GO:0071900 157 0.037
cell division GO:0051301 120 0.037
developmental maturation GO:0021700 193 0.037
cytokine production GO:0001816 319 0.036
aromatic compound catabolic process GO:0019439 286 0.035
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.035
regulation of mapk cascade GO:0043408 248 0.035
dna metabolic process GO:0006259 303 0.034
embryonic organ morphogenesis GO:0048562 276 0.034
cell adhesion GO:0007155 329 0.034
female gamete generation GO:0007292 74 0.034
protein localization to organelle GO:0033365 185 0.034
response to growth factor GO:0070848 198 0.033
muscle cell differentiation GO:0042692 261 0.033
positive regulation of mapk cascade GO:0043410 170 0.033
gtp catabolic process GO:0006184 143 0.033
response to organonitrogen compound GO:0010243 246 0.033
mrna metabolic process GO:0016071 84 0.033
transmembrane transport GO:0055085 412 0.033
rna processing GO:0006396 105 0.032
dephosphorylation GO:0016311 129 0.032
negative regulation of molecular function GO:0044092 258 0.032
synapse organization GO:0050808 125 0.032
small gtpase mediated signal transduction GO:0007264 97 0.032
urogenital system development GO:0001655 261 0.032
positive regulation of gtpase activity GO:0043547 85 0.032
cellular component assembly involved in morphogenesis GO:0010927 139 0.031
cell substrate adhesion GO:0031589 130 0.030
skeletal system development GO:0001501 356 0.030
cellular response to organonitrogen compound GO:0071417 145 0.030
purine ribonucleotide metabolic process GO:0009150 290 0.030
cilium assembly GO:0042384 81 0.030
carbohydrate metabolic process GO:0005975 230 0.029
rna splicing GO:0008380 54 0.029
negative regulation of phosphorylation GO:0042326 166 0.029
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.028
macromolecule catabolic process GO:0009057 281 0.028
regulation of mrna metabolic process GO:1903311 43 0.028
actin filament organization GO:0007015 113 0.028
development of primary sexual characteristics GO:0045137 143 0.027
nucleobase containing small molecule metabolic process GO:0055086 352 0.027
ribonucleotide metabolic process GO:0009259 291 0.027
regulation of cellular component biogenesis GO:0044087 181 0.027
cellular nitrogen compound catabolic process GO:0044270 280 0.027
muscle tissue development GO:0060537 308 0.026
guanosine containing compound metabolic process GO:1901068 144 0.026
rna splicing via transesterification reactions GO:0000375 43 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
purine nucleoside triphosphate catabolic process GO:0009146 203 0.026
nucleoside phosphate metabolic process GO:0006753 338 0.026
protein localization to membrane GO:0072657 108 0.026
oocyte axis specification GO:0007309 2 0.026
carbohydrate derivative catabolic process GO:1901136 231 0.025
neurotransmitter transport GO:0006836 76 0.025
regulation of purine nucleotide metabolic process GO:1900542 169 0.025
myotube differentiation GO:0014902 105 0.025
purine ribonucleoside metabolic process GO:0046128 241 0.025
endomembrane system organization GO:0010256 147 0.025
protein processing GO:0016485 163 0.024
neuron projection guidance GO:0097485 141 0.024
gtp metabolic process GO:0046039 144 0.024
epithelial cell development GO:0002064 159 0.024
purine nucleotide metabolic process GO:0006163 302 0.024
cellular response to hormone stimulus GO:0032870 150 0.024
organelle localization GO:0051640 179 0.024
negative regulation of cellular amine metabolic process GO:0033239 1 0.024
intracellular protein transport GO:0006886 204 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.023
apoptotic signaling pathway GO:0097190 306 0.023
sensory organ morphogenesis GO:0090596 242 0.023
genitalia development GO:0048806 37 0.023
establishment of protein localization to membrane GO:0090150 54 0.023
membrane organization GO:0061024 245 0.023
leukocyte differentiation GO:0002521 342 0.023
glycosyl compound metabolic process GO:1901657 246 0.023
ras protein signal transduction GO:0007265 77 0.023
skeletal muscle organ development GO:0060538 163 0.023
nucleoside triphosphate metabolic process GO:0009141 230 0.023
synaptic vesicle localization GO:0097479 59 0.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.022
sensory perception GO:0007600 245 0.022
mapk cascade GO:0000165 281 0.022
wnt signaling pathway GO:0016055 188 0.022
regulation of cellular response to stress GO:0080135 159 0.022
cellular amino acid metabolic process GO:0006520 103 0.022
lymphocyte differentiation GO:0030098 242 0.022
amine metabolic process GO:0009308 45 0.022
compound eye development GO:0048749 1 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
purine containing compound catabolic process GO:0072523 213 0.022
protein maturation GO:0051604 176 0.022
regulation of cellular catabolic process GO:0031329 242 0.022
neuroblast differentiation GO:0014016 2 0.022
mitotic cell cycle GO:0000278 195 0.022
nucleoside triphosphate catabolic process GO:0009143 205 0.022
vesicle localization GO:0051648 86 0.021
digestive tract development GO:0048565 190 0.021
spermatid differentiation GO:0048515 115 0.021
axonogenesis GO:0007409 274 0.021
stem cell development GO:0048864 219 0.021
regulation of binding GO:0051098 111 0.021
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.021
regulation of secretion by cell GO:1903530 249 0.021
peptidyl lysine modification GO:0018205 77 0.020
establishment of synaptic vesicle localization GO:0097480 57 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.020
camera type eye development GO:0043010 266 0.020
negative regulation of protein phosphorylation GO:0001933 126 0.020
lung development GO:0030324 164 0.020
axon guidance GO:0007411 141 0.020
glycoprotein metabolic process GO:0009100 116 0.020
regulation of cell migration GO:0030334 219 0.020
cellular response to dna damage stimulus GO:0006974 207 0.020
renal system development GO:0072001 225 0.020
mesodermal cell migration GO:0008078 4 0.020
regulation of cell activation GO:0050865 289 0.019
regulation of protein localization GO:0032880 231 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
negative regulation of cellular component organization GO:0051129 194 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
spermatid development GO:0007286 108 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
regulation of neural precursor cell proliferation GO:2000177 70 0.019
engulfment of apoptotic cell GO:0043652 3 0.019
mrna splicing via spliceosome GO:0000398 43 0.019
neural tube development GO:0021915 160 0.019
regulation of cell cycle process GO:0010564 160 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.019
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.018
stem cell maintenance GO:0019827 130 0.018
oocyte construction GO:0007308 2 0.018
negative regulation of phosphorus metabolic process GO:0010563 184 0.018
myeloid cell differentiation GO:0030099 233 0.018
response to peptide hormone GO:0043434 127 0.018
respiratory system development GO:0060541 190 0.018
regulation of ras gtpase activity GO:0032318 88 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
digestive system development GO:0055123 200 0.018
neurotransmitter secretion GO:0007269 62 0.018
asymmetric neuroblast division GO:0055059 1 0.018
regulation of nucleotide catabolic process GO:0030811 122 0.017
cognition GO:0050890 149 0.017
regulation of neuron apoptotic process GO:0043523 122 0.017
monosaccharide metabolic process GO:0005996 106 0.017
positive regulation of nucleotide catabolic process GO:0030813 88 0.017
response to light stimulus GO:0009416 135 0.017
mitotic cell cycle process GO:1903047 159 0.017
neuron apoptotic process GO:0051402 142 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
peptidyl tyrosine phosphorylation GO:0018108 143 0.017
appendage development GO:0048736 166 0.017
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.017
cellular response to growth factor stimulus GO:0071363 197 0.017
regulation of engulfment of apoptotic cell GO:1901074 2 0.017
internal peptidyl lysine acetylation GO:0018393 42 0.017
oogenesis GO:0048477 56 0.017
nitrogen compound transport GO:0071705 271 0.016
cytoplasmic transport GO:0016482 234 0.016
protein ubiquitination GO:0016567 171 0.016
nucleotide catabolic process GO:0009166 217 0.016
bone development GO:0060348 120 0.016
respiratory tube development GO:0030323 167 0.016
segmentation GO:0035282 93 0.016
regulation of system process GO:0044057 200 0.016
microtubule based movement GO:0007018 84 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
establishment of organelle localization GO:0051656 122 0.016
morphogenesis of embryonic epithelium GO:0016331 159 0.016
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.016
peptidyl serine modification GO:0018209 83 0.016
chemotaxis GO:0006935 247 0.016
protein acylation GO:0043543 64 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.016
response to radiation GO:0009314 165 0.016
asymmetric stem cell division GO:0098722 3 0.015
forebrain development GO:0030900 302 0.015
multi multicellular organism process GO:0044706 109 0.015
lipid biosynthetic process GO:0008610 179 0.015
adult behavior GO:0030534 135 0.015
regulation of protein processing GO:0070613 96 0.015
regulation of neurotransmitter levels GO:0001505 87 0.015
appendage morphogenesis GO:0035107 149 0.015
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.015
neural precursor cell proliferation GO:0061351 121 0.015
positive regulation of nervous system development GO:0051962 221 0.015
t cell differentiation GO:0030217 174 0.015
signal transduction by p53 class mediator GO:0072331 51 0.015
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.015
regulation of map kinase activity GO:0043405 120 0.015
regulation of intracellular transport GO:0032386 159 0.015
defecation GO:0030421 1 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
synaptic transmission GO:0007268 329 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
protein catabolic process GO:0030163 221 0.015
muscle cell development GO:0055001 133 0.015
nucleoside catabolic process GO:0009164 206 0.015
ion transmembrane transport GO:0034220 361 0.015
oxidation reduction process GO:0055114 342 0.015
proteasomal protein catabolic process GO:0010498 98 0.015
organophosphate catabolic process GO:0046434 232 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
positive regulation of jnk cascade GO:0046330 46 0.014
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.014
positive regulation of cell development GO:0010720 237 0.014
cellular response to peptide GO:1901653 92 0.014
cell type specific apoptotic process GO:0097285 268 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
establishment of tissue polarity GO:0007164 28 0.014
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.014
intracellular mrna localization GO:0008298 4 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
stem cell proliferation GO:0072089 117 0.014
cell matrix adhesion GO:0007160 68 0.014
synapse assembly GO:0007416 56 0.014
t cell activation GO:0042110 289 0.014
regulation of actin filament based process GO:0032970 99 0.014
covalent chromatin modification GO:0016569 163 0.014
synaptic vesicle transport GO:0048489 57 0.014
regulation of organelle organization GO:0033043 289 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.013
hatching GO:0035188 4 0.013
multicellular organism growth GO:0035264 161 0.013
regulation of protein maturation GO:1903317 96 0.013
cellular protein catabolic process GO:0044257 155 0.013
regulation of endocytosis GO:0030100 69 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.013
anion transport GO:0006820 177 0.013
positive regulation of cell activation GO:0050867 158 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
regulation of hydrolase activity GO:0051336 246 0.013
activation of mapk activity GO:0000187 59 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
positive regulation of jun kinase activity GO:0043507 30 0.013
single organismal cell cell adhesion GO:0016337 131 0.013
regulation of striated muscle cell differentiation GO:0051153 81 0.013
regulation of mrna splicing via spliceosome GO:0048024 32 0.013
central nervous system neuron differentiation GO:0021953 162 0.013
placenta development GO:0001890 140 0.013
regulation of myeloid cell differentiation GO:0045637 96 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
organelle assembly GO:0070925 177 0.013
fertilization GO:0009566 127 0.013
regulation of cytokine production GO:0001817 266 0.013
negative regulation of proteolysis GO:0045861 74 0.013
tube formation GO:0035148 140 0.013
macromolecule glycosylation GO:0043413 55 0.013
regulation of cell adhesion GO:0030155 154 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
regulation of jnk cascade GO:0046328 62 0.013
establishment of planar polarity GO:0001736 28 0.012
gene silencing GO:0016458 38 0.012
neural tube formation GO:0001841 108 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
mrna processing GO:0006397 63 0.012
regulation of cell projection organization GO:0031344 206 0.012
immune effector process GO:0002252 321 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
negative regulation of protein processing GO:0010955 79 0.012
nucleotide metabolic process GO:0009117 332 0.012
developmental cell growth GO:0048588 84 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
lymphocyte proliferation GO:0046651 164 0.012
striated muscle tissue development GO:0014706 293 0.012
actomyosin structure organization GO:0031032 56 0.012
positive regulation of secretion GO:0051047 130 0.012
b cell activation GO:0042113 161 0.012
single fertilization GO:0007338 82 0.012
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.012
jnk cascade GO:0007254 72 0.012
embryonic epithelial tube formation GO:0001838 130 0.012
anatomical structure homeostasis GO:0060249 145 0.012
regulation of protein transport GO:0051223 163 0.012
extracellular structure organization GO:0043062 148 0.012
positive regulation of gtp catabolic process GO:0033126 85 0.012
phosphatidic acid biosynthetic process GO:0006654 2 0.012
primary neural tube formation GO:0014020 95 0.012
nuclear import GO:0051170 95 0.012
regulation of lymphocyte differentiation GO:0045619 107 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.012
ribonucleoside catabolic process GO:0042454 206 0.011
single organism cell adhesion GO:0098602 156 0.011
positive regulation of map kinase activity GO:0043406 84 0.011
regulation of membrane potential GO:0042391 192 0.011
methylation GO:0032259 134 0.011
peptidyl serine phosphorylation GO:0018105 74 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
glycosylation GO:0070085 62 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
regulation of rna splicing GO:0043484 37 0.011
regulation of mitotic cell cycle phase transition GO:1901990 73 0.011
maintenance of location GO:0051235 89 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
learning or memory GO:0007611 148 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
organism emergence from protective structure GO:0071684 4 0.011
somitogenesis GO:0001756 69 0.011
regulation of secretion GO:0051046 274 0.011
cellularization GO:0007349 1 0.011
regulation of neuron differentiation GO:0045664 281 0.011
positive regulation of stress activated mapk cascade GO:0032874 48 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
kidney development GO:0001822 213 0.011
regulation of fibroblast proliferation GO:0048145 34 0.011
homeostasis of number of cells GO:0048872 210 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.011
protein import into nucleus GO:0006606 95 0.011
regulation of nucleocytoplasmic transport GO:0046822 73 0.011
glucose metabolic process GO:0006006 92 0.011
regulation of jun kinase activity GO:0043506 40 0.011
actin filament bundle assembly GO:0051017 40 0.011
regulation of anatomical structure size GO:0090066 178 0.011
stress activated protein kinase signaling cascade GO:0031098 81 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
negative regulation of cell adhesion GO:0007162 45 0.011
neuron death GO:0070997 154 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
tissue homeostasis GO:0001894 115 0.010
regulation of cell motility GO:2000145 236 0.010
leukocyte proliferation GO:0070661 172 0.010
morphogenesis of a branching epithelium GO:0061138 193 0.010
protein localization to plasma membrane GO:0072659 57 0.010
energy derivation by oxidation of organic compounds GO:0015980 77 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.010
transmission of nerve impulse GO:0019226 76 0.010
gland development GO:0048732 330 0.010
regulation of rho protein signal transduction GO:0035023 71 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
protein targeting GO:0006605 143 0.010
circulatory system process GO:0003013 197 0.010
positive regulation of immature t cell proliferation GO:0033091 4 0.010
mrna transcription GO:0009299 4 0.010
extracellular matrix organization GO:0030198 147 0.010
translation GO:0006412 93 0.010
blood circulation GO:0008015 195 0.010
response to lipopolysaccharide GO:0032496 128 0.010
female sex differentiation GO:0046660 84 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
macromolecule methylation GO:0043414 120 0.010
limb development GO:0060173 166 0.010
mitotic nuclear division GO:0007067 48 0.010
protein localization to nucleus GO:0034504 121 0.010
negative regulation of protein maturation GO:1903318 79 0.010
positive regulation of apoptotic process GO:0043065 217 0.010
negative regulation of synaptic vesicle transport GO:1902804 3 0.010
meiotic cell cycle process GO:1903046 77 0.010
clathrin coat assembly GO:0048268 2 0.010
cellular protein complex assembly GO:0043623 116 0.010
cation transmembrane transport GO:0098655 266 0.010
establishment of protein localization to organelle GO:0072594 118 0.010
oocyte anterior posterior axis specification GO:0007314 2 0.010

Prrc2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.035
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.032
central nervous system disease DOID:331 0 0.020
disease of cellular proliferation DOID:14566 0 0.016
inherited metabolic disorder DOID:655 0 0.016
bone remodeling disease DOID:0080005 0 0.015
bone disease DOID:0080001 0 0.015
osteopetrosis DOID:13533 0 0.015
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015
osteosclerosis DOID:4254 0 0.015
neurodegenerative disease DOID:1289 0 0.015
cancer DOID:162 0 0.015
brain disease DOID:936 0 0.013
immune system disease DOID:2914 0 0.011
hematopoietic system disease DOID:74 0 0.011
organ system cancer DOID:0050686 0 0.011