Mus musculus

41 known processes

Inpp5e

inositol polyphosphate-5-phosphatase E

(Aliases: 1200002L24Rik,mKIAA0123,72kDa)

Inpp5e biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ras protein signal transduction GO:0007265 77 0.079
small gtpase mediated signal transduction GO:0007264 97 0.076
nucleoside phosphate catabolic process GO:1901292 222 0.047
protein modification by small protein conjugation or removal GO:0070647 207 0.044
negative regulation of cell development GO:0010721 169 0.043
cellular amine metabolic process GO:0044106 44 0.041
organophosphate catabolic process GO:0046434 232 0.040
cellular nitrogen compound catabolic process GO:0044270 280 0.040
amine metabolic process GO:0009308 45 0.037
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
purine ribonucleotide metabolic process GO:0009150 290 0.037
cellular amino acid metabolic process GO:0006520 103 0.037
regulation of cellular amino acid metabolic process GO:0006521 5 0.036
nucleotide metabolic process GO:0009117 332 0.035
organonitrogen compound catabolic process GO:1901565 264 0.035
purine ribonucleotide catabolic process GO:0009154 208 0.035
ribonucleoside metabolic process GO:0009119 245 0.035
nucleotide catabolic process GO:0009166 217 0.034
purine containing compound metabolic process GO:0072521 311 0.033
glycosyl compound catabolic process GO:1901658 206 0.032
purine nucleotide metabolic process GO:0006163 302 0.032
nucleoside catabolic process GO:0009164 206 0.032
negative regulation of cellular component organization GO:0051129 194 0.031
organic cyclic compound catabolic process GO:1901361 295 0.031
immune effector process GO:0002252 321 0.031
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.030
ribonucleoside triphosphate metabolic process GO:0009199 220 0.030
regulation of cellular ketone metabolic process GO:0010565 66 0.030
purine nucleoside triphosphate metabolic process GO:0009144 226 0.029
nucleoside metabolic process GO:0009116 246 0.029
aromatic compound catabolic process GO:0019439 286 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.029
membrane organization GO:0061024 245 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.028
apoptotic signaling pathway GO:0097190 306 0.028
rho protein signal transduction GO:0007266 32 0.028
regulation of purine nucleotide catabolic process GO:0033121 122 0.027
glycosyl compound metabolic process GO:1901657 246 0.027
negative regulation of nervous system development GO:0051961 156 0.027
macromolecule catabolic process GO:0009057 281 0.027
nucleoside phosphate metabolic process GO:0006753 338 0.027
forebrain development GO:0030900 302 0.027
endocytosis GO:0006897 168 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
regulation of gtp catabolic process GO:0033124 113 0.026
ribonucleotide metabolic process GO:0009259 291 0.026
regulation of neuron differentiation GO:0045664 281 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
regulation of cellular amine metabolic process GO:0033238 20 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
actin cytoskeleton organization GO:0030036 220 0.026
muscle tissue development GO:0060537 308 0.026
regulation of purine nucleotide metabolic process GO:1900542 169 0.026
purine nucleoside catabolic process GO:0006152 205 0.026
ribonucleotide catabolic process GO:0009261 208 0.026
cellular response to dna damage stimulus GO:0006974 207 0.025
nucleoside triphosphate catabolic process GO:0009143 205 0.025
regulation of cellular catabolic process GO:0031329 242 0.025
purine nucleoside metabolic process GO:0042278 241 0.025
protein localization to organelle GO:0033365 185 0.025
cellular ketone metabolic process GO:0042180 84 0.025
carbohydrate derivative catabolic process GO:1901136 231 0.024
organonitrogen compound biosynthetic process GO:1901566 192 0.024
axonogenesis GO:0007409 274 0.023
positive regulation of cellular catabolic process GO:0031331 148 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.023
regulation of apoptotic signaling pathway GO:2001233 197 0.023
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.023
regulation of cell projection organization GO:0031344 206 0.023
cation transport GO:0006812 399 0.023
regulation of nucleoside metabolic process GO:0009118 130 0.022
protein catabolic process GO:0030163 221 0.022
regulation of nucleotide metabolic process GO:0006140 169 0.022
response to organonitrogen compound GO:0010243 246 0.022
Mouse
regulation of cellular response to stress GO:0080135 159 0.022
homeostasis of number of cells GO:0048872 210 0.022
Mouse
peptidyl amino acid modification GO:0018193 336 0.022
positive regulation of hydrolase activity GO:0051345 148 0.022
endomembrane system organization GO:0010256 147 0.022
positive regulation of nucleotide catabolic process GO:0030813 88 0.022
organelle assembly GO:0070925 177 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.021
purine containing compound catabolic process GO:0072523 213 0.021
covalent chromatin modification GO:0016569 163 0.021
regulation of ras gtpase activity GO:0032318 88 0.021
modification dependent protein catabolic process GO:0019941 133 0.021
wnt signaling pathway GO:0016055 188 0.021
regulation of cytokine production GO:0001817 266 0.021
Mouse
heterocycle catabolic process GO:0046700 280 0.021
regulation of cell cycle GO:0051726 281 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.020
cilium morphogenesis GO:0060271 102 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
ribonucleoside triphosphate catabolic process GO:0009203 199 0.020
positive regulation of nucleoside metabolic process GO:0045979 91 0.020
leukocyte differentiation GO:0002521 342 0.020
Mouse
cytoplasmic transport GO:0016482 234 0.020
cilium assembly GO:0042384 81 0.020
gtp metabolic process GO:0046039 144 0.020
guanosine containing compound catabolic process GO:1901069 144 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
protein ubiquitination GO:0016567 171 0.020
positive regulation of gtp catabolic process GO:0033126 85 0.020
microtubule based process GO:0007017 236 0.020
negative regulation of immune system process GO:0002683 209 0.020
Mouse
regulation of nucleotide catabolic process GO:0030811 122 0.019
regulation of hydrolase activity GO:0051336 246 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
cellular component assembly involved in morphogenesis GO:0010927 139 0.019
positive regulation of nervous system development GO:0051962 221 0.019
cytokine production GO:0001816 319 0.019
Mouse
regulation of mapk cascade GO:0043408 248 0.019
male gamete generation GO:0048232 285 0.019
gtp catabolic process GO:0006184 143 0.018
mapk cascade GO:0000165 281 0.018
cellular lipid metabolic process GO:0044255 323 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
dna metabolic process GO:0006259 303 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
regulation of ras protein signal transduction GO:0046578 114 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
Mouse
maintenance of location GO:0051235 89 0.017
cellular homeostasis GO:0019725 240 0.017
guanosine containing compound metabolic process GO:1901068 144 0.017
regulation of organelle organization GO:0033043 289 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
Mouse
purine nucleotide catabolic process GO:0006195 211 0.017
cellular response to biotic stimulus GO:0071216 92 0.017
positive regulation of protein modification process GO:0031401 299 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
carbohydrate metabolic process GO:0005975 230 0.017
cellular response to hormone stimulus GO:0032870 150 0.016
intracellular protein transport GO:0006886 204 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
camera type eye development GO:0043010 266 0.016
protein maturation GO:0051604 176 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
positive regulation of gtpase activity GO:0043547 85 0.016
positive regulation of cell development GO:0010720 237 0.016
positive regulation of neuron differentiation GO:0045666 141 0.016
regionalization GO:0003002 337 0.016
positive regulation of organelle organization GO:0010638 128 0.016
dephosphorylation GO:0016311 129 0.016
sensory organ morphogenesis GO:0090596 242 0.016
telencephalon development GO:0021537 186 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
skeletal system development GO:0001501 356 0.016
synaptic transmission GO:0007268 329 0.016
regulation of cytoskeleton organization GO:0051493 122 0.015
transmission of nerve impulse GO:0019226 76 0.015
regulation of cellular component size GO:0032535 121 0.015
negative regulation of molecular function GO:0044092 258 0.015
embryonic epithelial tube formation GO:0001838 130 0.015
organelle localization GO:0051640 179 0.015
divalent inorganic cation transport GO:0072511 178 0.015
striated muscle tissue development GO:0014706 293 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
regulation of membrane potential GO:0042391 192 0.015
cognition GO:0050890 149 0.015
regulation of multi organism process GO:0043900 111 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
cell type specific apoptotic process GO:0097285 268 0.015
positive regulation of cell death GO:0010942 224 0.015
Mouse
regulation of protein localization GO:0032880 231 0.015
regulation of transferase activity GO:0051338 263 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
compound eye development GO:0048749 1 0.014
muscle cell differentiation GO:0042692 261 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
chromatin organization GO:0006325 206 0.014
actin filament organization GO:0007015 113 0.014
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
establishment of organelle localization GO:0051656 122 0.014
regulation of kinase activity GO:0043549 249 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
Mouse
neuron death GO:0070997 154 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
Mouse
regulation of cell activation GO:0050865 289 0.014
Mouse
organophosphate biosynthetic process GO:0090407 122 0.014
Mouse
response to growth factor GO:0070848 198 0.014
cation transmembrane transport GO:0098655 266 0.014
cellular protein complex assembly GO:0043623 116 0.014
asymmetric stem cell division GO:0098722 3 0.014
appendage development GO:0048736 166 0.014
regulation of homeostatic process GO:0032844 182 0.014
Mouse
methylation GO:0032259 134 0.014
protein processing GO:0016485 163 0.014
regulation of defense response GO:0031347 233 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
regulation of cell cycle process GO:0010564 160 0.013
blood circulation GO:0008015 195 0.013
positive regulation of transferase activity GO:0051347 167 0.013
negative regulation of protein modification process GO:0031400 163 0.013
pallium development GO:0021543 120 0.013
regulation of neuron projection development GO:0010975 169 0.013
spermatogenesis GO:0007283 284 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
stem cell differentiation GO:0048863 268 0.013
regulation of secretion by cell GO:1903530 249 0.013
divalent metal ion transport GO:0070838 172 0.013
innate immune response GO:0045087 157 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
plasma membrane organization GO:0007009 90 0.013
multicellular organism growth GO:0035264 161 0.013
lipid biosynthetic process GO:0008610 179 0.013
Mouse
protein targeting GO:0006605 143 0.013
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.013
microtubule based movement GO:0007018 84 0.013
urogenital system development GO:0001655 261 0.013
sequestering of calcium ion GO:0051208 18 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
sequestering of metal ion GO:0051238 19 0.013
locomotory behavior GO:0007626 195 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
regulation of proteolysis GO:0030162 164 0.013
positive regulation of ras gtpase activity GO:0032320 65 0.013
circulatory system process GO:0003013 197 0.013
mitochondrion organization GO:0007005 134 0.013
defense response to other organism GO:0098542 197 0.013
anatomical structure homeostasis GO:0060249 145 0.013
Mouse
cellular protein catabolic process GO:0044257 155 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
Mouse
renal system development GO:0072001 225 0.012
tube formation GO:0035148 140 0.012
learning or memory GO:0007611 148 0.012
histone modification GO:0016570 159 0.012
kidney development GO:0001822 213 0.012
negative regulation of neuron differentiation GO:0045665 101 0.012
mitotic cell cycle process GO:1903047 159 0.012
action potential GO:0001508 78 0.012
regulation of secretion GO:0051046 274 0.012
organelle fission GO:0048285 170 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
positive regulation of mapk cascade GO:0043410 170 0.012
transmembrane transport GO:0055085 412 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
Mouse
chromatin modification GO:0016568 187 0.012
rna processing GO:0006396 105 0.012
regulation of anatomical structure size GO:0090066 178 0.012
myeloid cell homeostasis GO:0002262 114 0.012
Mouse
primary neural tube formation GO:0014020 95 0.012
germ cell development GO:0007281 185 0.012
chemotaxis GO:0006935 247 0.012
fertilization GO:0009566 127 0.012
t cell activation GO:0042110 289 0.012
negative regulation of cytokine production GO:0001818 84 0.012
Mouse
mitochondrion distribution GO:0048311 4 0.012
response to insulin GO:0032868 100 0.012
Mouse
nuclear division GO:0000280 158 0.012
smoothened signaling pathway GO:0007224 105 0.012
protein localization to nucleus GO:0034504 121 0.012
sensory perception GO:0007600 245 0.012
exocytosis GO:0006887 121 0.012
regulation of ion transport GO:0043269 215 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
blood vessel morphogenesis GO:0048514 285 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
digestive system development GO:0055123 200 0.011
regulation of actin cytoskeleton organization GO:0032956 84 0.011
adult behavior GO:0030534 135 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
skeletal muscle organ development GO:0060538 163 0.011
multicellular organismal signaling GO:0035637 91 0.011
lateral inhibition GO:0046331 1 0.011
response to organic cyclic compound GO:0014070 198 0.011
epithelial cell proliferation GO:0050673 174 0.011
lymphocyte differentiation GO:0030098 242 0.011
Mouse
regulation of actin filament based process GO:0032970 99 0.011
neuron migration GO:0001764 122 0.011
developmental maturation GO:0021700 193 0.011
positive regulation of protein catabolic process GO:0045732 60 0.011
response to peptide GO:1901652 136 0.011
Mouse
cell maturation GO:0048469 127 0.011
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.011
glycerolipid metabolic process GO:0046486 122 0.011
cellular response to lipid GO:0071396 145 0.011
regulation of cell motility GO:2000145 236 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
response to lipopolysaccharide GO:0032496 128 0.011
mitotic cell cycle GO:0000278 195 0.011
negative regulation of multi organism process GO:0043901 68 0.011
fat cell differentiation GO:0045444 160 0.011
neuronal action potential GO:0019228 54 0.011
ion transmembrane transport GO:0034220 361 0.011
regulation of system process GO:0044057 200 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
lung development GO:0030324 164 0.011
rab protein signal transduction GO:0032482 1 0.011
glycoprotein metabolic process GO:0009100 116 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
asymmetric neuroblast division GO:0055059 1 0.011
cellular chemical homeostasis GO:0055082 215 0.010
response to molecule of bacterial origin GO:0002237 143 0.010
retina development in camera type eye GO:0060041 119 0.010
maintenance of protein location in nucleus GO:0051457 2 0.010
digestive tract development GO:0048565 190 0.010
negative regulation of viral transcription GO:0032897 3 0.010
b cell activation GO:0042113 161 0.010
Mouse
regulation of t cell activation GO:0050863 170 0.010
epithelial tube formation GO:0072175 130 0.010
gland development GO:0048732 330 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
neuron apoptotic process GO:0051402 142 0.010
regulation of cell migration GO:0030334 219 0.010
neural tube formation GO:0001841 108 0.010
phospholipid metabolic process GO:0006644 87 0.010
myosin filament assembly GO:0031034 2 0.010
oocyte axis specification GO:0007309 2 0.010
spermatid development GO:0007286 108 0.010
canonical wnt signaling pathway GO:0060070 130 0.010
neuromuscular process GO:0050905 99 0.010
viral gene expression GO:0019080 3 0.010
neural precursor cell proliferation GO:0061351 121 0.010
regulation of chromosome organization GO:0033044 83 0.010
limb development GO:0060173 166 0.010
tissue homeostasis GO:0001894 115 0.010
Mouse
cerebellum development GO:0021549 77 0.010
tube closure GO:0060606 91 0.010

Inpp5e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.032
central nervous system disease DOID:331 0 0.016
immune system disease DOID:2914 0 0.011
musculoskeletal system disease DOID:17 0 0.010