Mus musculus

123 known processes

Dedd

death effector domain-containing

(Aliases: CASP8IP1,FLDED1,KE05,Dedpro1,DEFT)

Dedd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule catabolic process GO:0044265 206 0.063
protein modification by small protein conjugation or removal GO:0070647 207 0.062
macromolecule catabolic process GO:0009057 281 0.061
ras protein signal transduction GO:0007265 77 0.056
apoptotic signaling pathway GO:0097190 306 0.053
ubiquitin dependent protein catabolic process GO:0006511 129 0.053
regulation of organelle organization GO:0033043 289 0.050
negative regulation of cellular protein metabolic process GO:0032269 247 0.048
protein catabolic process GO:0030163 221 0.046
modification dependent protein catabolic process GO:0019941 133 0.044
protein modification by small protein conjugation GO:0032446 187 0.044
carbohydrate metabolic process GO:0005975 230 0.043
cellular amine metabolic process GO:0044106 44 0.041
cellular amino acid metabolic process GO:0006520 103 0.041
protein localization to organelle GO:0033365 185 0.040
modification dependent macromolecule catabolic process GO:0043632 133 0.040
regulation of apoptotic signaling pathway GO:2001233 197 0.039
aromatic compound catabolic process GO:0019439 286 0.039
regulation of cellular ketone metabolic process GO:0010565 66 0.039
amine metabolic process GO:0009308 45 0.038
regulation of cellular amine metabolic process GO:0033238 20 0.037
heterocycle catabolic process GO:0046700 280 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.037
organophosphate catabolic process GO:0046434 232 0.037
cellular protein catabolic process GO:0044257 155 0.037
negative regulation of molecular function GO:0044092 258 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.036
spermatogenesis GO:0007283 284 0.036
dna metabolic process GO:0006259 303 0.036
male gamete generation GO:0048232 285 0.036
regulation of cellular catabolic process GO:0031329 242 0.035
negative regulation of protein metabolic process GO:0051248 282 0.035
regulation of cell activation GO:0050865 289 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
nucleoside catabolic process GO:0009164 206 0.034
cellular ketone metabolic process GO:0042180 84 0.034
regulation of cellular amino acid metabolic process GO:0006521 5 0.034
purine nucleoside triphosphate catabolic process GO:0009146 203 0.034
cytoplasmic transport GO:0016482 234 0.034
mitotic cell cycle process GO:1903047 159 0.034
organic cyclic compound catabolic process GO:1901361 295 0.033
regulation of proteolysis GO:0030162 164 0.033
ribonucleotide metabolic process GO:0009259 291 0.033
purine nucleoside triphosphate metabolic process GO:0009144 226 0.033
positive regulation of cellular amine metabolic process GO:0033240 5 0.033
purine ribonucleotide catabolic process GO:0009154 208 0.033
purine nucleoside metabolic process GO:0042278 241 0.033
peptidyl amino acid modification GO:0018193 336 0.033
regulation of cell cycle GO:0051726 281 0.032
cellular response to dna damage stimulus GO:0006974 207 0.032
small gtpase mediated signal transduction GO:0007264 97 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.030
negative regulation of intracellular signal transduction GO:1902532 167 0.030
negative regulation of immune system process GO:0002683 209 0.029
posttranscriptional regulation of gene expression GO:0010608 155 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
protein maturation GO:0051604 176 0.029
regulation of intracellular transport GO:0032386 159 0.028
germ cell development GO:0007281 185 0.028
carbohydrate derivative catabolic process GO:1901136 231 0.027
proteasomal protein catabolic process GO:0010498 98 0.027
nucleotide metabolic process GO:0009117 332 0.027
leukocyte differentiation GO:0002521 342 0.027
t cell activation GO:0042110 289 0.027
nucleoside phosphate catabolic process GO:1901292 222 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
actin cytoskeleton organization GO:0030036 220 0.027
ribonucleoside triphosphate metabolic process GO:0009199 220 0.027
purine containing compound metabolic process GO:0072521 311 0.026
regulation of defense response GO:0031347 233 0.026
organelle fission GO:0048285 170 0.026
cytokine production GO:0001816 319 0.026
regulation of cell cycle process GO:0010564 160 0.026
nucleoside triphosphate metabolic process GO:0009141 230 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
lymphocyte proliferation GO:0046651 164 0.025
regulation of cell migration GO:0030334 219 0.025
nucleoside triphosphate catabolic process GO:0009143 205 0.025
transmembrane transport GO:0055085 412 0.025
organelle assembly GO:0070925 177 0.025
nitrogen compound transport GO:0071705 271 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.025
nucleobase containing small molecule metabolic process GO:0055086 352 0.025
purine containing compound catabolic process GO:0072523 213 0.025
immune effector process GO:0002252 321 0.025
ribose phosphate metabolic process GO:0019693 291 0.024
regulation of lymphocyte activation GO:0051249 240 0.024
regulation of protein catabolic process GO:0042176 108 0.024
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.024
protein processing GO:0016485 163 0.024
ribonucleoside catabolic process GO:0042454 206 0.024
negative regulation of protein modification process GO:0031400 163 0.024
response to organonitrogen compound GO:0010243 246 0.023
mitotic cell cycle GO:0000278 195 0.023
regulation of cellular response to stress GO:0080135 159 0.023
nucleoside metabolic process GO:0009116 246 0.023
inorganic cation transmembrane transport GO:0098662 207 0.023
positive regulation of protein modification process GO:0031401 299 0.023
regulation of establishment of protein localization GO:0070201 181 0.023
regulation of hydrolase activity GO:0051336 246 0.023
oocyte axis specification GO:0007309 2 0.023
wnt signaling pathway GO:0016055 188 0.023
cation transport GO:0006812 399 0.022
regulation of protein localization GO:0032880 231 0.022
regulation of multi organism process GO:0043900 111 0.022
gtp metabolic process GO:0046039 144 0.022
negative regulation of cell proliferation GO:0008285 296 0.022
innate immune response GO:0045087 157 0.022
purine nucleotide catabolic process GO:0006195 211 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
membrane organization GO:0061024 245 0.022
regulation of secretion GO:0051046 274 0.022
protein ubiquitination GO:0016567 171 0.022
endomembrane system organization GO:0010256 147 0.021
dna repair GO:0006281 107 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
mitochondrion organization GO:0007005 134 0.021
spermatid development GO:0007286 108 0.021
regionalization GO:0003002 337 0.021
regulation of cytokine production GO:0001817 266 0.021
response to lipopolysaccharide GO:0032496 128 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
ribonucleoside metabolic process GO:0009119 245 0.021
chromatin modification GO:0016568 187 0.021
histone modification GO:0016570 159 0.021
cellular response to cytokine stimulus GO:0071345 189 0.020
cation transmembrane transport GO:0098655 266 0.020
regulation of protein transport GO:0051223 163 0.020
regulation of chromosome organization GO:0033044 83 0.020
embryonic organ morphogenesis GO:0048562 276 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
regulation of secretion by cell GO:1903530 249 0.020
regulation of protein processing GO:0070613 96 0.019
negative regulation of cell cycle GO:0045786 123 0.019
regulation of mapk cascade GO:0043408 248 0.019
dephosphorylation GO:0016311 129 0.019
intracellular mrna localization GO:0008298 4 0.019
negative regulation of cellular component organization GO:0051129 194 0.019
organelle localization GO:0051640 179 0.019
response to molecule of bacterial origin GO:0002237 143 0.019
spermatid differentiation GO:0048515 115 0.019
regulation of transferase activity GO:0051338 263 0.018
nucleotide catabolic process GO:0009166 217 0.018
response to insulin GO:0032868 100 0.018
myeloid cell differentiation GO:0030099 233 0.018
negative regulation of phosphorus metabolic process GO:0010563 184 0.018
cellular response to lipid GO:0071396 145 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
mapk cascade GO:0000165 281 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
microtubule based process GO:0007017 236 0.018
response to radiation GO:0009314 165 0.018
negative regulation of protein phosphorylation GO:0001933 126 0.018
cell type specific apoptotic process GO:0097285 268 0.018
intracellular protein transport GO:0006886 204 0.018
positive regulation of cellular catabolic process GO:0031331 148 0.018
lymphocyte differentiation GO:0030098 242 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
compound eye development GO:0048749 1 0.017
chromatin organization GO:0006325 206 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
oocyte construction GO:0007308 2 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
regulation of cell motility GO:2000145 236 0.017
protein localization to nucleus GO:0034504 121 0.017
skeletal system development GO:0001501 356 0.017
negative regulation of apoptotic signaling pathway GO:2001234 104 0.017
covalent chromatin modification GO:0016569 163 0.017
regulation of peptidase activity GO:0052547 96 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
cellular homeostasis GO:0019725 240 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
intrinsic apoptotic signaling pathway GO:0097193 132 0.017
guanosine containing compound metabolic process GO:1901068 144 0.017
t cell differentiation GO:0030217 174 0.017
regulation of protein kinase activity GO:0045859 232 0.016
regulation of t cell activation GO:0050863 170 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
regulation of ion transport GO:0043269 215 0.016
nuclear transport GO:0051169 139 0.016
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.016
nuclear division GO:0000280 158 0.016
cell adhesion GO:0007155 329 0.016
inflammatory response GO:0006954 244 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
regulation of hormone levels GO:0010817 211 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
regulation of mitotic cell cycle GO:0007346 126 0.016
guanosine containing compound catabolic process GO:1901069 144 0.016
regulation of leukocyte differentiation GO:1902105 159 0.016
circadian rhythm GO:0007623 114 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
positive regulation of nervous system development GO:0051962 221 0.015
regulation of cytoskeleton organization GO:0051493 122 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
negative regulation of organelle organization GO:0010639 90 0.015
translation GO:0006412 93 0.015
skeletal muscle organ development GO:0060538 163 0.015
defense response to other organism GO:0098542 197 0.015
maternal determination of anterior posterior axis embryo GO:0008358 2 0.015
ion transmembrane transport GO:0034220 361 0.015
muscle cell differentiation GO:0042692 261 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
digestive system development GO:0055123 200 0.015
locomotory behavior GO:0007626 195 0.015
developmental maturation GO:0021700 193 0.015
methylation GO:0032259 134 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
response to growth factor GO:0070848 198 0.015
camera type eye development GO:0043010 266 0.014
digestive tract development GO:0048565 190 0.014
single organism nuclear import GO:1902593 95 0.014
regulation of response to wounding GO:1903034 189 0.014
striated muscle tissue development GO:0014706 293 0.014
leukocyte mediated immunity GO:0002443 174 0.014
regulation of membrane potential GO:0042391 192 0.014
protein targeting GO:0006605 143 0.014
muscle tissue development GO:0060537 308 0.014
cellular lipid metabolic process GO:0044255 323 0.014
endocytosis GO:0006897 168 0.014
carbohydrate homeostasis GO:0033500 128 0.014
regulation of neuron differentiation GO:0045664 281 0.014
homeostasis of number of cells GO:0048872 210 0.014
pole plasm assembly GO:0007315 2 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
synaptic transmission GO:0007268 329 0.014
regulation of lymphocyte differentiation GO:0045619 107 0.014
response to oxidative stress GO:0006979 123 0.014
response to acid chemical GO:0001101 111 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
blood vessel morphogenesis GO:0048514 285 0.014
neuron death GO:0070997 154 0.014
positive regulation of proteolysis GO:0045862 85 0.013
b cell activation GO:0042113 161 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
positive regulation of cell death GO:0010942 224 0.013
exocytosis GO:0006887 121 0.013
positive regulation of cell development GO:0010720 237 0.013
rhythmic process GO:0048511 174 0.013
glucose homeostasis GO:0042593 128 0.013
tube closure GO:0060606 91 0.013
regulation of neuron death GO:1901214 134 0.013
regulation of innate immune response GO:0045088 91 0.013
regulation of t cell proliferation GO:0042129 92 0.013
response to organic cyclic compound GO:0014070 198 0.013
positive regulation of protein catabolic process GO:0045732 60 0.013
gtp catabolic process GO:0006184 143 0.013
rna interference GO:0016246 2 0.013
regulation of lymphocyte proliferation GO:0050670 117 0.013
neuron apoptotic process GO:0051402 142 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
response to peptide hormone GO:0043434 127 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
defense response to bacterium GO:0042742 119 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
regulation of anatomical structure size GO:0090066 178 0.013
peptidyl serine modification GO:0018209 83 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
leukocyte proliferation GO:0070661 172 0.012
maintenance of location GO:0051235 89 0.012
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
cilium morphogenesis GO:0060271 102 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
blood circulation GO:0008015 195 0.012
cytokine mediated signaling pathway GO:0019221 115 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
actin filament organization GO:0007015 113 0.012
multicellular organism growth GO:0035264 161 0.012
regulation of cell cycle phase transition GO:1901987 77 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
regulation of body fluid levels GO:0050878 162 0.012
tube formation GO:0035148 140 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
regulation of actin filament based process GO:0032970 99 0.012
regulation of cell adhesion GO:0030155 154 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
regulation of protein maturation GO:1903317 96 0.012
rna processing GO:0006396 105 0.012
adult behavior GO:0030534 135 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
positive regulation of organelle organization GO:0010638 128 0.012
urogenital system development GO:0001655 261 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
regulation of cellular component size GO:0032535 121 0.011
protein import GO:0017038 101 0.011
gland development GO:0048732 330 0.011
female gamete generation GO:0007292 74 0.011
oogenesis GO:0048477 56 0.011
activation of immune response GO:0002253 138 0.011
divalent inorganic cation transport GO:0072511 178 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
cell activation involved in immune response GO:0002263 126 0.011
negative regulation of cell development GO:0010721 169 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
angiogenesis GO:0001525 201 0.011
regulation of cell projection organization GO:0031344 206 0.011
cognition GO:0050890 149 0.011
regulation of homeostatic process GO:0032844 182 0.011
positive regulation of cell activation GO:0050867 158 0.011
meiosis i GO:0007127 60 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
macromolecule methylation GO:0043414 120 0.011
skin development GO:0043588 220 0.011
plasma membrane organization GO:0007009 90 0.011
axonogenesis GO:0007409 274 0.011
cell division GO:0051301 120 0.011
sequestering of metal ion GO:0051238 19 0.011
protein alkylation GO:0008213 81 0.011
mitotic cytokinesis GO:0000281 4 0.011
stress activated protein kinase signaling cascade GO:0031098 81 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
negative regulation of protein processing GO:0010955 79 0.011
regulation of kinase activity GO:0043549 249 0.011
protein localization to membrane GO:0072657 108 0.011
blastocyst development GO:0001824 80 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
response to light stimulus GO:0009416 135 0.011
negative regulation of defense response GO:0031348 77 0.011
positive regulation of growth GO:0045927 104 0.011
jnk cascade GO:0007254 72 0.011
limb development GO:0060173 166 0.011
transmission of nerve impulse GO:0019226 76 0.011
meiotic nuclear division GO:0007126 115 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
regulation of translation GO:0006417 71 0.011
multi multicellular organism process GO:0044706 109 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
positive regulation of defense response GO:0031349 124 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
response to inorganic substance GO:0010035 96 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
response to peptide GO:1901652 136 0.011
protein import into nucleus GO:0006606 95 0.011
sensory organ morphogenesis GO:0090596 242 0.011
amide transport GO:0042886 138 0.011
peptidyl serine phosphorylation GO:0018105 74 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.010
protein methylation GO:0006479 81 0.010
nuclear import GO:0051170 95 0.010
regulation of inflammatory response GO:0050727 147 0.010
posttranscriptional gene silencing by rna GO:0035194 10 0.010
stress activated mapk cascade GO:0051403 80 0.010
cell maturation GO:0048469 127 0.010
negative regulation of mitotic cell cycle GO:0045930 58 0.010
meiotic cell cycle GO:0051321 122 0.010
microtubule based movement GO:0007018 84 0.010
response to oxygen levels GO:0070482 62 0.010
lymphocyte activation involved in immune response GO:0002285 93 0.010
microtubule cytoskeleton organization GO:0000226 157 0.010
g1 s transition of mitotic cell cycle GO:0000082 57 0.010
hormone secretion GO:0046879 128 0.010
myeloid cell homeostasis GO:0002262 114 0.010
cellularization GO:0007349 1 0.010
negative regulation of cellular catabolic process GO:0031330 47 0.010
wound healing GO:0042060 157 0.010
cellular response to molecule of bacterial origin GO:0071219 83 0.010
development of primary sexual characteristics GO:0045137 143 0.010
protein polyubiquitination GO:0000209 33 0.010
cellular response to acid chemical GO:0071229 68 0.010
positive regulation of lymphocyte activation GO:0051251 140 0.010
organonitrogen compound biosynthetic process GO:1901566 192 0.010
cell junction organization GO:0034330 77 0.010
positive regulation of transferase activity GO:0051347 167 0.010
extrinsic apoptotic signaling pathway GO:0097191 126 0.010
negative regulation of kinase activity GO:0033673 81 0.010
regulation of nucleotide catabolic process GO:0030811 122 0.010
localization within membrane GO:0051668 4 0.010
cellular response to peptide GO:1901653 92 0.010
positive regulation of intracellular transport GO:0032388 70 0.010
viral gene expression GO:0019080 3 0.010

Dedd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
disease of cellular proliferation DOID:14566 0 0.019
cancer DOID:162 0 0.017
musculoskeletal system disease DOID:17 0 0.015
organ system cancer DOID:0050686 0 0.014
muscular disease DOID:0080000 0 0.014
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.012
immune system disease DOID:2914 0 0.012
cardiovascular system disease DOID:1287 0 0.010