Mus musculus

61 known processes

Exo1

exonuclease 1

(Aliases: 5730442G03Rik,Msa)

Exo1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.847
microtubule cytoskeleton organization GO:0000226 157 0.644
meiotic nuclear division GO:0007126 115 0.637
organelle fission GO:0048285 170 0.626
nuclear division GO:0000280 158 0.534
mitotic cell cycle GO:0000278 195 0.515
mitotic cell cycle process GO:1903047 159 0.465
meiotic cell cycle process GO:1903046 77 0.409
dna repair GO:0006281 107 0.353
Human
meiotic cell cycle GO:0051321 122 0.350
negative regulation of cell cycle phase transition GO:1901988 48 0.343
female meiosis chromosome segregation GO:0016321 1 0.316
regulation of cell cycle GO:0051726 281 0.299
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.246
dna endoreduplication GO:0042023 4 0.223
metaphase plate congression GO:0051310 2 0.219
cellular response to dna damage stimulus GO:0006974 207 0.201
Human
regulation of cell cycle process GO:0010564 160 0.196
regulation of mitotic cell cycle phase transition GO:1901990 73 0.183
reciprocal dna recombination GO:0035825 16 0.175
reciprocal meiotic recombination GO:0007131 16 0.168
microtubule based process GO:0007017 236 0.159
double strand break repair GO:0006302 48 0.159
regulation of mitotic cell cycle GO:0007346 126 0.156
male meiosis GO:0007140 37 0.152
dna recombination GO:0006310 92 0.136
mitotic sister chromatid cohesion GO:0007064 1 0.132
synapsis GO:0007129 34 0.125
negative regulation of cellular component organization GO:0051129 194 0.117
centrosome cycle GO:0007098 23 0.112
protein catabolic process GO:0030163 221 0.111
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.101
male gamete generation GO:0048232 285 0.093
regulation of cell division GO:0051302 76 0.088
dna dependent dna replication GO:0006261 24 0.081
meiosis i GO:0007127 60 0.080
cell division GO:0051301 120 0.080
positive regulation of cell cycle GO:0045787 92 0.078
regulation of organelle organization GO:0033043 289 0.078
chromosome organization involved in meiosis GO:0070192 39 0.075
mitotic chromosome condensation GO:0007076 1 0.074
cellular macromolecule catabolic process GO:0044265 206 0.073
Human
spermatogenesis GO:0007283 284 0.072
regulation of mitosis GO:0007088 29 0.070
organelle assembly GO:0070925 177 0.070
response to cell cycle checkpoint signaling GO:0072396 1 0.069
centrosome organization GO:0051297 26 0.068
chromatin organization GO:0006325 206 0.068
negative regulation of organelle organization GO:0010639 90 0.067
negative regulation of protein metabolic process GO:0051248 282 0.060
regulation of cellular component size GO:0032535 121 0.059
cell cycle g1 s phase transition GO:0044843 57 0.058
mitotic nuclear division GO:0007067 48 0.057
regulation of cell cycle phase transition GO:1901987 77 0.056
positive regulation of cell cycle process GO:0090068 61 0.055
centrosome separation GO:0051299 4 0.055
macromolecule catabolic process GO:0009057 281 0.054
Human
cellular amino acid metabolic process GO:0006520 103 0.053
establishment of organelle localization GO:0051656 122 0.052
development of primary sexual characteristics GO:0045137 143 0.052
microtubule organizing center organization GO:0031023 28 0.051
histone threonine phosphorylation GO:0035405 1 0.050
histone modification GO:0016570 159 0.050
dna biosynthetic process GO:0071897 22 0.049
maintenance of location GO:0051235 89 0.048
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.048
protein modification by small protein conjugation GO:0032446 187 0.047
cellular ketone metabolic process GO:0042180 84 0.046
positive regulation of histone h3 k9 methylation GO:0051574 4 0.046
heterocycle catabolic process GO:0046700 280 0.046
Human
organic acid biosynthetic process GO:0016053 86 0.045
cellularization GO:0007349 1 0.043
meiotic dna repair synthesis GO:0000711 4 0.043
cellular protein catabolic process GO:0044257 155 0.043
protein ubiquitination GO:0016567 171 0.041
chiasma assembly GO:0051026 6 0.040
positive regulation of tendon cell differentiation GO:2001051 1 0.039
regulation of cytoskeleton organization GO:0051493 122 0.038
chromosome segregation GO:0007059 48 0.037
purine nucleotide metabolic process GO:0006163 302 0.036
spindle assembly GO:0051225 13 0.034
dna packaging GO:0006323 30 0.034
regulation of microtubule cytoskeleton organization GO:0070507 37 0.033
positive regulation of chromosome segregation GO:0051984 4 0.033
macromolecule methylation GO:0043414 120 0.032
response to radiation GO:0009314 165 0.032
negative regulation of mitotic cell cycle GO:0045930 58 0.032
cellular protein complex assembly GO:0043623 116 0.031
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.031
positive regulation of mitotic cell cycle GO:0045931 41 0.030
regulation of cellular ketone metabolic process GO:0010565 66 0.030
protein modification by small protein conjugation or removal GO:0070647 207 0.030
centrosome duplication GO:0051298 16 0.030
regulation of protein catabolic process GO:0042176 108 0.029
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.029
oxidation reduction process GO:0055114 342 0.029
folic acid containing compound metabolic process GO:0006760 3 0.029
histone h3 k9 dimethylation GO:0036123 4 0.028
negative regulation of cell cycle GO:0045786 123 0.028
g1 s transition of mitotic cell cycle GO:0000082 57 0.028
male meiosis i GO:0007141 16 0.027
mitotic sister chromatid segregation GO:0000070 14 0.027
regulation of cellular amino acid metabolic process GO:0006521 5 0.027
mitotic centrosome separation GO:0007100 4 0.026
establishment of meiotic spindle orientation GO:0051296 1 0.026
purine nucleoside catabolic process GO:0006152 205 0.026
positive regulation of apoptotic process GO:0043065 217 0.025
negative regulation of cell cycle process GO:0010948 69 0.025
organelle localization GO:0051640 179 0.025
regulation of anatomical structure size GO:0090066 178 0.025
regulation of cellular amine metabolic process GO:0033238 20 0.025
multicellular organism growth GO:0035264 161 0.024
regulation of response to wounding GO:1903034 189 0.023
gonad development GO:0008406 141 0.023
cellular response to cytokine stimulus GO:0071345 189 0.023
protein polymerization GO:0051258 57 0.023
positive regulation of mitotic metaphase anaphase transition GO:0045842 2 0.023
apoptotic signaling pathway GO:0097190 306 0.023
negative regulation of cell development GO:0010721 169 0.023
ribonucleoside monophosphate catabolic process GO:0009158 57 0.023
nucleoside monophosphate catabolic process GO:0009125 59 0.023
spindle assembly involved in female meiosis GO:0007056 3 0.023
nucleoside phosphate metabolic process GO:0006753 338 0.022
regulation of protein localization GO:0032880 231 0.022
regulation of centrosome cycle GO:0046605 10 0.022
purine nucleoside monophosphate catabolic process GO:0009128 58 0.022
skeletal system morphogenesis GO:0048705 203 0.022
spermatid development GO:0007286 108 0.022
chromatin modification GO:0016568 187 0.022
ossification GO:0001503 216 0.022
intrinsic apoptotic signaling pathway GO:0097193 132 0.022
positive regulation of cell death GO:0010942 224 0.022
spindle organization GO:0007051 28 0.021
regulation of mitotic sister chromatid segregation GO:0033047 12 0.021
striated muscle myosin thick filament assembly GO:0071688 1 0.021
positive regulation of programmed cell death GO:0043068 218 0.021
male sex differentiation GO:0046661 109 0.021
ribose phosphate metabolic process GO:0019693 291 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.021
organonitrogen compound catabolic process GO:1901565 264 0.021
blood vessel morphogenesis GO:0048514 285 0.020
positive regulation of cell cycle phase transition GO:1901989 17 0.020
glycosyl compound metabolic process GO:1901657 246 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
nucleoside catabolic process GO:0009164 206 0.020
placenta development GO:0001890 140 0.020
mitochondrion organization GO:0007005 134 0.020
positive regulation of organelle organization GO:0010638 128 0.019
sister chromatid segregation GO:0000819 20 0.019
negative regulation of cell proliferation GO:0008285 296 0.019
positive regulation of g0 to g1 transition GO:0070318 2 0.019
endomembrane system organization GO:0010256 147 0.019
regulation of chromosome organization GO:0033044 83 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
heterochromatin organization GO:0070828 4 0.018
regulation of cell cycle g1 s phase transition GO:1902806 35 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.018
regulation of cell cycle g2 m phase transition GO:1902749 10 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
protein methylation GO:0006479 81 0.018
organophosphate catabolic process GO:0046434 232 0.018
nucleobase containing small molecule metabolic process GO:0055086 352 0.018
mitotic recombination GO:0006312 3 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
cellular amine metabolic process GO:0044106 44 0.017
regulation of b cell tolerance induction GO:0002661 2 0.017
methylation GO:0032259 134 0.017
energy derivation by oxidation of organic compounds GO:0015980 77 0.017
single fertilization GO:0007338 82 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
water soluble vitamin metabolic process GO:0006767 10 0.017
immune effector process GO:0002252 321 0.017
carboxylic acid biosynthetic process GO:0046394 86 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
establishment or maintenance of cell polarity GO:0007163 86 0.016
positive regulation of protein modification process GO:0031401 299 0.016
cleavage furrow formation GO:0036089 2 0.016
monocarboxylic acid biosynthetic process GO:0072330 61 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.015
proteasomal protein catabolic process GO:0010498 98 0.015
regulation of intracellular transport GO:0032386 159 0.015
centriole assembly GO:0098534 6 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.015
chromatin mediated maintenance of transcription GO:0048096 2 0.015
gland development GO:0048732 330 0.015
actin filament organization GO:0007015 113 0.015
cation transport GO:0006812 399 0.015
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.014
modification dependent protein catabolic process GO:0019941 133 0.014
regulation of metaphase anaphase transition of cell cycle GO:1902099 9 0.014
regulation of neuron differentiation GO:0045664 281 0.014
forebrain development GO:0030900 302 0.014
apical constriction GO:0003383 4 0.014
regulation of protein complex assembly GO:0043254 83 0.014
spermatid differentiation GO:0048515 115 0.014
protein polyubiquitination GO:0000209 33 0.014
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.014
response to light stimulus GO:0009416 135 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
membrane organization GO:0061024 245 0.014
actin polymerization or depolymerization GO:0008154 54 0.013
leukocyte proliferation GO:0070661 172 0.013
actin filament polymerization GO:0030041 44 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
negative regulation of mitotic sister chromatid segregation GO:0033048 7 0.013
translesion synthesis GO:0019985 1 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
peptidyl lysine trimethylation GO:0018023 12 0.013
positive regulation of cellular amine metabolic process GO:0033240 5 0.013
regulation of chromosome segregation GO:0051983 21 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
dna replication GO:0006260 52 0.013
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.013
mitotic spindle organization GO:0007052 10 0.013
blastocyst formation GO:0001825 33 0.013
organic cyclic compound catabolic process GO:1901361 295 0.013
Human
negative regulation of cell division GO:0051782 24 0.013
negative regulation of protein processing GO:0010955 79 0.013
blastocyst development GO:0001824 80 0.013
establishment of spindle orientation GO:0051294 15 0.013
cytokinesis GO:0000910 17 0.012
mitotic sister chromatid separation GO:0051306 9 0.012
regulation of cellular response to stress GO:0080135 159 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
spindle assembly involved in mitosis GO:0090307 4 0.012
wound healing GO:0042060 157 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
regulation of actin polymerization or depolymerization GO:0008064 45 0.012
homeostasis of number of cells GO:0048872 210 0.012
response to organonitrogen compound GO:0010243 246 0.012
amine metabolic process GO:0009308 45 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
microtubule sliding GO:0051012 1 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
mapk cascade GO:0000165 281 0.012
rhythmic process GO:0048511 174 0.012
stem cell maintenance GO:0019827 130 0.012
regulation of histone modification GO:0031056 56 0.012
g0 to g1 transition GO:0045023 3 0.012
cellular respiration GO:0045333 38 0.012
lymphocyte differentiation GO:0030098 242 0.012
alpha beta t cell activation GO:0046631 91 0.011
cell cycle switching GO:0060184 1 0.011
protein secretion GO:0009306 111 0.011
divalent metal ion transport GO:0070838 172 0.011
regulation of proteolysis GO:0030162 164 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
positive regulation of cell development GO:0010720 237 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
covalent chromatin modification GO:0016569 163 0.011
positive regulation of cytoskeleton organization GO:0051495 49 0.011
lipid biosynthetic process GO:0008610 179 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
establishment of spindle localization GO:0051293 19 0.011
atp catabolic process GO:0006200 55 0.011
tube closure GO:0060606 91 0.011
embryonic epithelial tube formation GO:0001838 130 0.011
mitotic cytokinesis GO:0000281 4 0.011
glycosyl compound catabolic process GO:1901658 206 0.010
molting cycle GO:0042303 90 0.010
nucleotide metabolic process GO:0009117 332 0.010
protein localization to chromosome centromeric region GO:0071459 1 0.010
carbohydrate derivative catabolic process GO:1901136 231 0.010
ubiquitin dependent protein catabolic process GO:0006511 129 0.010
actin mediated cell contraction GO:0070252 15 0.010
generation of precursor metabolites and energy GO:0006091 103 0.010
anatomical structure homeostasis GO:0060249 145 0.010
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.010
negative regulation of cell fate specification GO:0009996 4 0.010
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.010

Exo1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.081
disease of anatomical entity DOID:7 0 0.081
thoracic cancer DOID:5093 0 0.081
cancer DOID:162 0 0.081
disease of cellular proliferation DOID:14566 0 0.081
organ system cancer DOID:0050686 0 0.081
hematopoietic system disease DOID:74 0 0.071
blood platelet disease DOID:2218 0 0.048
hemorrhagic disease DOID:2213 0 0.048
blood coagulation disease DOID:1247 0 0.048
congenital hypoplastic anemia DOID:1342 0 0.029
aplastic anemia DOID:12449 0 0.029
bone marrow disease DOID:4961 0 0.029
anemia DOID:2355 0 0.029
breast cancer DOID:1612 0 0.020
fanconi s anemia DOID:13636 0 0.013
gastrointestinal system cancer DOID:3119 0 0.012
intestinal cancer DOID:10155 0 0.012