Mus musculus

15 known processes

Upf2

UPF2 regulator of nonsense transcripts homolog (yeast)

Upf2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin organization GO:0006325 206 0.145
cellular nitrogen compound catabolic process GO:0044270 280 0.073
chromatin modification GO:0016568 187 0.067
covalent chromatin modification GO:0016569 163 0.061
heterocycle catabolic process GO:0046700 280 0.057
mitotic cell cycle GO:0000278 195 0.056
organelle fission GO:0048285 170 0.055
histone modification GO:0016570 159 0.054
regulation of cellular ketone metabolic process GO:0010565 66 0.048
protein modification by small protein conjugation or removal GO:0070647 207 0.047
mitotic cell cycle process GO:1903047 159 0.047
nucleoside catabolic process GO:0009164 206 0.045
purine containing compound metabolic process GO:0072521 311 0.043
ribonucleoside triphosphate catabolic process GO:0009203 199 0.043
glycosyl compound metabolic process GO:1901657 246 0.041
cell type specific apoptotic process GO:0097285 268 0.041
regulation of cell cycle GO:0051726 281 0.040
ribose phosphate metabolic process GO:0019693 291 0.040
organic cyclic compound catabolic process GO:1901361 295 0.039
myeloid cell differentiation GO:0030099 233 0.039
apoptotic signaling pathway GO:0097190 306 0.039
cellular response to dna damage stimulus GO:0006974 207 0.039
axonogenesis GO:0007409 274 0.038
nucleotide catabolic process GO:0009166 217 0.037
nuclear division GO:0000280 158 0.036
nucleotide metabolic process GO:0009117 332 0.036
posttranscriptional regulation of gene expression GO:0010608 155 0.035
purine ribonucleoside metabolic process GO:0046128 241 0.035
blood vessel morphogenesis GO:0048514 285 0.035
regulation of cell migration GO:0030334 219 0.035
cellular ketone metabolic process GO:0042180 84 0.034
nucleoside metabolic process GO:0009116 246 0.034
aromatic compound catabolic process GO:0019439 286 0.033
protein localization to organelle GO:0033365 185 0.033
protein localization to nucleus GO:0034504 121 0.033
regulation of organelle organization GO:0033043 289 0.032
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.032
regulation of mitotic cell cycle GO:0007346 126 0.031
protein maturation GO:0051604 176 0.031
regulation of protein stability GO:0031647 52 0.030
chemotaxis GO:0006935 247 0.030
histone lysine methylation GO:0034968 50 0.029
purine nucleoside metabolic process GO:0042278 241 0.029
cellular response to lipid GO:0071396 145 0.029
cellular amine metabolic process GO:0044106 44 0.029
nucleoside phosphate metabolic process GO:0006753 338 0.028
neural precursor cell proliferation GO:0061351 121 0.028
establishment of protein localization to organelle GO:0072594 118 0.028
negative regulation of cellular component organization GO:0051129 194 0.028
cellular macromolecule catabolic process GO:0044265 206 0.028
macromolecule methylation GO:0043414 120 0.027
homeostasis of number of cells GO:0048872 210 0.027
rna processing GO:0006396 105 0.026
sodium ion transport GO:0006814 73 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
protein processing GO:0016485 163 0.026
purine nucleotide catabolic process GO:0006195 211 0.025
protein modification by small protein removal GO:0070646 21 0.025
protein targeting GO:0006605 143 0.025
microtubule cytoskeleton organization GO:0000226 157 0.025
regulation of cell cycle process GO:0010564 160 0.025
regulation of proteolysis GO:0030162 164 0.025
purine containing compound catabolic process GO:0072523 213 0.024
skeletal system development GO:0001501 356 0.024
nucleoside triphosphate catabolic process GO:0009143 205 0.024
cell division GO:0051301 120 0.024
response to organic cyclic compound GO:0014070 198 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
regulation of hydrolase activity GO:0051336 246 0.024
carboxylic acid biosynthetic process GO:0046394 86 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.024
response to growth factor GO:0070848 198 0.023
male gamete generation GO:0048232 285 0.023
organophosphate catabolic process GO:0046434 232 0.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.023
negative regulation of organelle organization GO:0010639 90 0.023
modification dependent macromolecule catabolic process GO:0043632 133 0.023
regulation of peptidase activity GO:0052547 96 0.023
protein modification by small protein conjugation GO:0032446 187 0.023
negative regulation of molecular function GO:0044092 258 0.023
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.023
defense response to other organism GO:0098542 197 0.022
blood circulation GO:0008015 195 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
purine nucleoside catabolic process GO:0006152 205 0.022
purine ribonucleotide catabolic process GO:0009154 208 0.022
regionalization GO:0003002 337 0.022
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
methylation GO:0032259 134 0.021
protein ubiquitination GO:0016567 171 0.021
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.021
nuclear import GO:0051170 95 0.021
sensory organ morphogenesis GO:0090596 242 0.021
compound eye development GO:0048749 1 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
regulation of chromatin silencing GO:0031935 2 0.020
regulation of cellular amine metabolic process GO:0033238 20 0.020
negative regulation of cell cycle GO:0045786 123 0.020
microtubule based process GO:0007017 236 0.020
regulation of cellular amino acid metabolic process GO:0006521 5 0.020
purine ribonucleotide metabolic process GO:0009150 290 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
adult behavior GO:0030534 135 0.020
proteasomal protein catabolic process GO:0010498 98 0.019
stem cell maintenance GO:0019827 130 0.019
ion transmembrane transport GO:0034220 361 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
ossification GO:0001503 216 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
germ cell development GO:0007281 185 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
organic acid biosynthetic process GO:0016053 86 0.019
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
dna repair GO:0006281 107 0.018
striated muscle tissue development GO:0014706 293 0.018
anatomical structure homeostasis GO:0060249 145 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
sensory perception GO:0007600 245 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
heart morphogenesis GO:0003007 178 0.018
demethylation GO:0070988 23 0.018
transmembrane transport GO:0055085 412 0.018
intracellular protein transport GO:0006886 204 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
regulation of secretion GO:0051046 274 0.018
stem cell proliferation GO:0072089 117 0.018
forebrain development GO:0030900 302 0.017
defense response to bacterium GO:0042742 119 0.017
regulation of endopeptidase activity GO:0052548 89 0.017
cation transport GO:0006812 399 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
gene silencing GO:0016458 38 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
stem cell development GO:0048864 219 0.017
cellular response to organic cyclic compound GO:0071407 87 0.017
positive regulation of cell death GO:0010942 224 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
wnt signaling pathway GO:0016055 188 0.017
skeletal system morphogenesis GO:0048705 203 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.017
cellular response to abiotic stimulus GO:0071214 56 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
female sex differentiation GO:0046660 84 0.016
meiotic cell cycle GO:0051321 122 0.016
morphogenesis of embryonic epithelium GO:0016331 159 0.016
camera type eye development GO:0043010 266 0.016
immune effector process GO:0002252 321 0.016
regulation of cell cycle checkpoint GO:1901976 9 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
dna metabolic process GO:0006259 303 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
epithelial cell proliferation GO:0050673 174 0.015
peptidyl amino acid modification GO:0018193 336 0.015
protein polyubiquitination GO:0000209 33 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
endomembrane system organization GO:0010256 147 0.015
response to light stimulus GO:0009416 135 0.015
divalent metal ion transport GO:0070838 172 0.015
skeletal muscle organ development GO:0060538 163 0.015
regulation of ion transport GO:0043269 215 0.015
ear development GO:0043583 200 0.015
positive regulation of cell development GO:0010720 237 0.015
cellular amino acid metabolic process GO:0006520 103 0.015
regulation of hormone levels GO:0010817 211 0.015
mitotic nuclear division GO:0007067 48 0.015
retina development in camera type eye GO:0060041 119 0.015
negative regulation of protein modification process GO:0031400 163 0.015
protein deubiquitination GO:0016579 19 0.015
leukocyte apoptotic process GO:0071887 71 0.015
negative regulation of protein processing GO:0010955 79 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
regulation of t cell activation GO:0050863 170 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
angiogenesis GO:0001525 201 0.014
cellular response to nutrient levels GO:0031669 64 0.014
histone h3 k9 methylation GO:0051567 17 0.014
bmp signaling pathway GO:0030509 93 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
innate immune response GO:0045087 157 0.014
amine metabolic process GO:0009308 45 0.014
histone h3 k9 acetylation GO:0043970 5 0.014
histone demethylation GO:0016577 13 0.014
regulation of protein localization GO:0032880 231 0.014
protein import into nucleus GO:0006606 95 0.014
response to testosterone GO:0033574 3 0.014
muscle tissue development GO:0060537 308 0.014
regulation of histone h3 k9 methylation GO:0051570 8 0.014
mrna metabolic process GO:0016071 84 0.014
telencephalon development GO:0021537 186 0.014
negative regulation of cell cycle process GO:0010948 69 0.014
cell cycle checkpoint GO:0000075 47 0.013
negative regulation of mitotic cell cycle GO:0045930 58 0.013
negative regulation of cell cycle phase transition GO:1901988 48 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
stem cell differentiation GO:0048863 268 0.013
single organism nuclear import GO:1902593 95 0.013
regulation of cellular response to stress GO:0080135 159 0.013
sensory perception of sound GO:0007605 97 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
regulation of secretion by cell GO:1903530 249 0.013
histone methylation GO:0016571 71 0.013
retinal blood vessel morphogenesis GO:0061304 3 0.013
organelle localization GO:0051640 179 0.013
neuron migration GO:0001764 122 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
nitrogen compound transport GO:0071705 271 0.013
fatty acid metabolic process GO:0006631 121 0.013
spermatogenesis GO:0007283 284 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.013
sensory perception of mechanical stimulus GO:0050954 107 0.013
negative regulation of cell development GO:0010721 169 0.013
regulation of membrane potential GO:0042391 192 0.013
regulation of cell cycle phase transition GO:1901987 77 0.013
atp catabolic process GO:0006200 55 0.013
response to transforming growth factor beta GO:0071559 88 0.013
ras protein signal transduction GO:0007265 77 0.013
positive regulation of proteolysis GO:0045862 85 0.012
regulation of cell growth GO:0001558 91 0.012
glycoprotein metabolic process GO:0009100 116 0.012
nucleobase containing small molecule metabolic process GO:0055086 352 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
multicellular organismal signaling GO:0035637 91 0.012
palate development GO:0060021 76 0.012
regulation of protein transport GO:0051223 163 0.012
cytoplasmic transport GO:0016482 234 0.012
regulation of lymphocyte differentiation GO:0045619 107 0.012
dna conformation change GO:0071103 37 0.012
regulation of cytokine production GO:0001817 266 0.012
cation transmembrane transport GO:0098655 266 0.012
regulation of intracellular transport GO:0032386 159 0.012
cation homeostasis GO:0055080 212 0.012
regulation of cell division GO:0051302 76 0.012
purine nucleoside monophosphate catabolic process GO:0009128 58 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
regulation of t cell differentiation GO:0045580 83 0.012
cell growth GO:0016049 130 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
lipid localization GO:0010876 126 0.012
nucleoside monophosphate catabolic process GO:0009125 59 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
myeloid cell homeostasis GO:0002262 114 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
negative regulation of chromosome organization GO:2001251 30 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.012
histone lysine demethylation GO:0070076 13 0.012
maintenance of location GO:0051235 89 0.012
intracellular receptor signaling pathway GO:0030522 74 0.012
neuronal action potential GO:0019228 54 0.012
regulation of response to alcohol GO:1901419 2 0.012
regulation of fatty acid biosynthetic process GO:0042304 12 0.012
response to lipopolysaccharide GO:0032496 128 0.011
developmental maturation GO:0021700 193 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
macromolecule catabolic process GO:0009057 281 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.011
response to radiation GO:0009314 165 0.011
dna recombination GO:0006310 92 0.011
calcium ion homeostasis GO:0055074 127 0.011
action potential GO:0001508 78 0.011
regulation of leukocyte apoptotic process GO:2000106 56 0.011
regulation of chromosome organization GO:0033044 83 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
digestive tract morphogenesis GO:0048546 147 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
protein homotrimerization GO:0070207 4 0.011
protein catabolic process GO:0030163 221 0.011
protein methylation GO:0006479 81 0.011
development of primary sexual characteristics GO:0045137 143 0.011
positive regulation of protein modification process GO:0031401 299 0.011
negative regulation of cell fate specification GO:0009996 4 0.011
t cell activation GO:0042110 289 0.011
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.011
b cell activation GO:0042113 161 0.011
oocyte axis specification GO:0007309 2 0.011
alpha beta t cell activation GO:0046631 91 0.011
regulation of cell projection organization GO:0031344 206 0.011
ear morphogenesis GO:0042471 118 0.011
positive regulation of histone h3 k9 methylation GO:0051574 4 0.011
cilium morphogenesis GO:0060271 102 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
regulation of stem cell proliferation GO:0072091 78 0.011
response to oxidative stress GO:0006979 123 0.011
cellular response to extracellular stimulus GO:0031668 81 0.011
muscle contraction GO:0006936 101 0.010
cell maturation GO:0048469 127 0.010
negative regulation of t helper 2 cell differentiation GO:0045629 4 0.010
small gtpase mediated signal transduction GO:0007264 97 0.010
regulation of neuron differentiation GO:0045664 281 0.010
cellular homeostasis GO:0019725 240 0.010
regulation of cellular response to growth factor stimulus GO:0090287 82 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
cardiac muscle tissue development GO:0048738 130 0.010
protein alkylation GO:0008213 81 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
monocarboxylic acid biosynthetic process GO:0072330 61 0.010
transmission of nerve impulse GO:0019226 76 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
regulation of protein catabolic process GO:0042176 108 0.010
nucleus organization GO:0006997 45 0.010
muscle cell differentiation GO:0042692 261 0.010
positive regulation of stem cell proliferation GO:2000648 59 0.010
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.010
regulation of histone modification GO:0031056 56 0.010

Upf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.049
disease of cellular proliferation DOID:14566 0 0.049
disease of anatomical entity DOID:7 0 0.040
musculoskeletal system disease DOID:17 0 0.040
organ system cancer DOID:0050686 0 0.034
immune system disease DOID:2914 0 0.015
connective tissue disease DOID:65 0 0.012