Mus musculus

66 known processes

Cenpk

centromere protein K

(Aliases: Solzt,BB232189,B130045K24Rik,C530004N04Rik,Cenp-K,Solt)

Cenpk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.722
meiosis i GO:0007127 60 0.620
dna conformation change GO:0071103 37 0.583
dna repair GO:0006281 107 0.539
negative regulation of cell cycle GO:0045786 123 0.453
mitotic cell cycle GO:0000278 195 0.442
negative regulation of cell cycle phase transition GO:1901988 48 0.421
organelle assembly GO:0070925 177 0.410
regulation of mitotic cell cycle phase transition GO:1901990 73 0.408
nuclear division GO:0000280 158 0.386
cellular macromolecule catabolic process GO:0044265 206 0.378
mitotic cell cycle checkpoint GO:0007093 31 0.371
microtubule cytoskeleton organization GO:0000226 157 0.350
mitotic cell cycle process GO:1903047 159 0.330
cell cycle checkpoint GO:0000075 47 0.325
organelle fission GO:0048285 170 0.322
regulation of cell cycle GO:0051726 281 0.309
regulation of cell cycle process GO:0010564 160 0.300
meiotic nuclear division GO:0007126 115 0.298
regulation of cell cycle phase transition GO:1901987 77 0.297
cellular response to dna damage stimulus GO:0006974 207 0.293
mitotic chromosome condensation GO:0007076 1 0.286
cell division GO:0051301 120 0.252
negative regulation of mitotic cell cycle GO:0045930 58 0.250
ubiquitin dependent protein catabolic process GO:0006511 129 0.243
mitotic nuclear division GO:0007067 48 0.229
female meiosis chromosome segregation GO:0016321 1 0.226
regulation of mitotic cell cycle GO:0007346 126 0.185
cellular protein catabolic process GO:0044257 155 0.172
dna biosynthetic process GO:0071897 22 0.165
microtubule based process GO:0007017 236 0.164
negative regulation of cell cycle process GO:0010948 69 0.153
protein catabolic process GO:0030163 221 0.146
regulation of proteasomal protein catabolic process GO:0061136 46 0.146
modification dependent protein catabolic process GO:0019941 133 0.133
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.131
meiotic cell cycle GO:0051321 122 0.127
histone threonine phosphorylation GO:0035405 1 0.122
regulation of mitosis GO:0007088 29 0.117
mitotic sister chromatid segregation GO:0000070 14 0.117
dna recombination GO:0006310 92 0.116
negative regulation of nuclear division GO:0051784 19 0.112
regulation of cell division GO:0051302 76 0.111
nucleoside phosphate catabolic process GO:1901292 222 0.109
double strand break repair GO:0006302 48 0.108
ribonucleoside catabolic process GO:0042454 206 0.108
nucleoside triphosphate catabolic process GO:0009143 205 0.100
mitotic recombination GO:0006312 3 0.095
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.094
organonitrogen compound catabolic process GO:1901565 264 0.092
meiotic cell cycle process GO:1903046 77 0.090
chromatin organization GO:0006325 206 0.089
purine nucleoside catabolic process GO:0006152 205 0.087
spindle assembly involved in mitosis GO:0090307 4 0.082
female meiotic division GO:0007143 21 0.080
negative regulation of cellular component organization GO:0051129 194 0.080
regulation of organelle organization GO:0033043 289 0.080
dna packaging GO:0006323 30 0.079
centrosome cycle GO:0007098 23 0.076
centromere complex assembly GO:0034508 3 0.075
regulation of transferase activity GO:0051338 263 0.075
microtubule organizing center organization GO:0031023 28 0.073
development of primary sexual characteristics GO:0045137 143 0.073
purine nucleotide metabolic process GO:0006163 302 0.072
dna replication GO:0006260 52 0.069
synapsis GO:0007129 34 0.069
regulation of mitotic sister chromatid separation GO:0010965 12 0.069
heterocycle catabolic process GO:0046700 280 0.066
male meiosis GO:0007140 37 0.066
purine ribonucleoside metabolic process GO:0046128 241 0.065
germ cell development GO:0007281 185 0.064
gonad development GO:0008406 141 0.063
protein maturation GO:0051604 176 0.063
nucleoside metabolic process GO:0009116 246 0.062
translesion synthesis GO:0019985 1 0.061
maintenance of location GO:0051235 89 0.061
meiotic chromosome segregation GO:0045132 19 0.060
cellular nitrogen compound catabolic process GO:0044270 280 0.059
response to radiation GO:0009314 165 0.059
proteasomal protein catabolic process GO:0010498 98 0.059
modification dependent macromolecule catabolic process GO:0043632 133 0.059
intrinsic apoptotic signaling pathway GO:0097193 132 0.058
positive regulation of cell cycle GO:0045787 92 0.058
nucleoside triphosphate metabolic process GO:0009141 230 0.056
cellular amino acid metabolic process GO:0006520 103 0.055
nucleobase containing small molecule metabolic process GO:0055086 352 0.054
spindle assembly involved in meiosis GO:0090306 4 0.054
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.053
male gamete generation GO:0048232 285 0.053
nucleoside catabolic process GO:0009164 206 0.051
regulation of protein localization GO:0032880 231 0.050
double strand break repair via homologous recombination GO:0000724 21 0.050
spindle checkpoint GO:0031577 12 0.047
negative regulation of mitosis GO:0045839 10 0.047
regulation of meiotic cell cycle phase transition GO:1901993 3 0.046
apoptotic signaling pathway GO:0097190 306 0.046
wnt signaling pathway GO:0016055 188 0.046
regulation of chromosome segregation GO:0051983 21 0.044
purine nucleoside triphosphate catabolic process GO:0009146 203 0.043
regulation of dna replication GO:0006275 17 0.043
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.043
macromolecule catabolic process GO:0009057 281 0.043
multicellular organism growth GO:0035264 161 0.043
establishment of organelle localization GO:0051656 122 0.042
dna dependent dna replication GO:0006261 24 0.042
purine containing compound metabolic process GO:0072521 311 0.042
ribonucleotide metabolic process GO:0009259 291 0.041
dna endoreduplication GO:0042023 4 0.041
spindle assembly involved in female meiosis GO:0007056 3 0.041
chromatin assembly or disassembly GO:0006333 16 0.041
glycosyl compound metabolic process GO:1901657 246 0.040
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
sister chromatid segregation GO:0000819 20 0.039
purine ribonucleotide catabolic process GO:0009154 208 0.039
purine ribonucleotide metabolic process GO:0009150 290 0.039
cellular amine metabolic process GO:0044106 44 0.038
posttranscriptional regulation of gene expression GO:0010608 155 0.038
chromatin modification GO:0016568 187 0.037
nucleoside monophosphate metabolic process GO:0009123 85 0.036
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.036
ribonucleoside monophosphate catabolic process GO:0009158 57 0.036
mitotic spindle checkpoint GO:0071174 9 0.036
cellular ketone metabolic process GO:0042180 84 0.035
amine metabolic process GO:0009308 45 0.034
regulation of nuclear division GO:0051783 56 0.034
recombinational repair GO:0000725 21 0.034
negative regulation of protein metabolic process GO:0051248 282 0.033
purine nucleoside monophosphate metabolic process GO:0009126 81 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.033
nucleoside monophosphate catabolic process GO:0009125 59 0.033
spindle assembly GO:0051225 13 0.033
aromatic compound catabolic process GO:0019439 286 0.033
male gonad development GO:0008584 88 0.033
macromolecule methylation GO:0043414 120 0.032
organophosphate catabolic process GO:0046434 232 0.031
regulation of protein kinase activity GO:0045859 232 0.031
purine ribonucleoside catabolic process GO:0046130 205 0.031
regulation of kinase activity GO:0043549 249 0.031
regulation of microtubule based process GO:0032886 52 0.031
atp catabolic process GO:0006200 55 0.030
nucleoside phosphate metabolic process GO:0006753 338 0.030
regulation of chromosome organization GO:0033044 83 0.030
genitalia development GO:0048806 37 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
regulation of proteolysis GO:0030162 164 0.030
glycosyl compound catabolic process GO:1901658 206 0.030
positive regulation of kinase activity GO:0033674 155 0.030
positive regulation of protein modification process GO:0031401 299 0.029
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.029
endocytosis GO:0006897 168 0.029
mitotic cytokinesis GO:0000281 4 0.029
cellular response to organonitrogen compound GO:0071417 145 0.029
positive regulation of mitotic cell cycle GO:0045931 41 0.029
organic cyclic compound catabolic process GO:1901361 295 0.029
purine nucleoside metabolic process GO:0042278 241 0.029
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.029
spindle organization GO:0007051 28 0.029
centrosome separation GO:0051299 4 0.029
dna replication independent nucleosome assembly GO:0006336 1 0.028
regulation of protein maturation GO:1903317 96 0.028
negative regulation of meiotic cell cycle phase transition GO:1901994 3 0.028
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.028
purine nucleoside monophosphate catabolic process GO:0009128 58 0.028
carbohydrate derivative catabolic process GO:1901136 231 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.027
negative regulation of cell division GO:0051782 24 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
positive regulation of cell development GO:0010720 237 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.027
mitotic sister chromatid separation GO:0051306 9 0.027
spermatid differentiation GO:0048515 115 0.027
attachment of spindle microtubules to kinetochore GO:0008608 4 0.026
response to ionizing radiation GO:0010212 42 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
peptidyl amino acid modification GO:0018193 336 0.025
negative regulation of intracellular signal transduction GO:1902532 167 0.025
negative regulation of mitotic sister chromatid segregation GO:0033048 7 0.025
regulation of metaphase anaphase transition of cell cycle GO:1902099 9 0.025
spermatid development GO:0007286 108 0.025
spermatogenesis GO:0007283 284 0.025
regulation of cellular ketone metabolic process GO:0010565 66 0.024
lymphocyte mediated immunity GO:0002449 139 0.024
dna catabolic process GO:0006308 19 0.024
dna catabolic process exonucleolytic GO:0000738 3 0.024
atp metabolic process GO:0046034 75 0.024
heterochromatin organization GO:0070828 4 0.024
nucleotide catabolic process GO:0009166 217 0.024
ribonucleoside metabolic process GO:0009119 245 0.024
positive regulation of apoptotic process GO:0043065 217 0.024
regulation of apoptotic signaling pathway GO:2001233 197 0.023
positive regulation of cell death GO:0010942 224 0.023
regulation of intracellular transport GO:0032386 159 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.023
leukocyte differentiation GO:0002521 342 0.023
microtubule based movement GO:0007018 84 0.023
protein ubiquitination GO:0016567 171 0.022
purine nucleoside triphosphate metabolic process GO:0009144 226 0.022
regulation of meiosis i GO:0060631 7 0.022
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.021
nucleocytoplasmic transport GO:0006913 139 0.021
cell fate commitment GO:0045165 210 0.021
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.021
metaphase plate congression GO:0051310 2 0.021
mitotic sister chromatid cohesion GO:0007064 1 0.021
positive regulation of programmed cell death GO:0043068 218 0.021
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.020
positive regulation of hydrolase activity GO:0051345 148 0.020
chromosome condensation GO:0030261 10 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
centrosome duplication GO:0051298 16 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
gland development GO:0048732 330 0.020
placenta development GO:0001890 140 0.019
regulation of t cell activation GO:0050863 170 0.019
negative regulation of transferase activity GO:0051348 85 0.019
chromosome separation GO:0051304 14 0.019
regulation of double strand break repair via homologous recombination GO:0010569 2 0.019
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
developmental maturation GO:0021700 193 0.018
nuclear transport GO:0051169 139 0.018
regulation of cytoskeleton organization GO:0051493 122 0.018
rho protein signal transduction GO:0007266 32 0.018
regulation of cellular response to stress GO:0080135 159 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
muscle cell differentiation GO:0042692 261 0.017
negative regulation of protein catabolic process GO:0042177 36 0.017
female gamete generation GO:0007292 74 0.017
fertilization GO:0009566 127 0.017
chromosome segregation GO:0007059 48 0.017
digestive system development GO:0055123 200 0.017
cellular response to abiotic stimulus GO:0071214 56 0.017
mitotic spindle assembly checkpoint GO:0007094 7 0.017
smoothened signaling pathway GO:0007224 105 0.017
regulation of protein catabolic process GO:0042176 108 0.016
negative regulation of molecular function GO:0044092 258 0.016
rna interference GO:0016246 2 0.016
stem cell differentiation GO:0048863 268 0.016
response to light stimulus GO:0009416 135 0.016
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.016
regulation of nuclear cell cycle dna replication GO:0033262 2 0.016
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
chromatin remodeling at centromere GO:0031055 2 0.016
protein processing GO:0016485 163 0.016
organelle localization GO:0051640 179 0.015
response to organic cyclic compound GO:0014070 198 0.015
methylation GO:0032259 134 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
positive regulation of transferase activity GO:0051347 167 0.015
regulation of cell cycle g1 s phase transition GO:1902806 35 0.015
negative regulation of cellular catabolic process GO:0031330 47 0.015
cytokinesis GO:0000910 17 0.015
negative regulation of dna replication GO:0008156 4 0.015
protein import GO:0017038 101 0.015
regulation of hydrolase activity GO:0051336 246 0.014
chromatin assembly GO:0031497 13 0.014
negative regulation of protein maturation GO:1903318 79 0.014
regulation of cell projection organization GO:0031344 206 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
purine containing compound catabolic process GO:0072523 213 0.014
chromosome organization involved in meiosis GO:0070192 39 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
digestive tract development GO:0048565 190 0.014
dephosphorylation GO:0016311 129 0.014
positive regulation of nervous system development GO:0051962 221 0.014
cilium morphogenesis GO:0060271 102 0.014
reciprocal meiotic recombination GO:0007131 16 0.014
histone acetylation GO:0016573 41 0.014
mesodermal cell migration GO:0008078 4 0.014
cell adhesion GO:0007155 329 0.014
regulation of cell activation GO:0050865 289 0.014
cellular response to organic cyclic compound GO:0071407 87 0.014
negative regulation of cellular protein catabolic process GO:1903363 22 0.014
immune effector process GO:0002252 321 0.013
intracellular protein transport GO:0006886 204 0.013
negative regulation of sister chromatid segregation GO:0033046 7 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
mrna metabolic process GO:0016071 84 0.013
b cell differentiation GO:0030183 78 0.013
replication fork protection GO:0048478 1 0.013
negative regulation of organelle organization GO:0010639 90 0.013
tube formation GO:0035148 140 0.013
neural tube formation GO:0001841 108 0.012
positive regulation of cell activation GO:0050867 158 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
neural tube closure GO:0001843 90 0.012
blastocyst development GO:0001824 80 0.012
response to organonitrogen compound GO:0010243 246 0.012
neural tube development GO:0021915 160 0.012
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.012
leukocyte mediated immunity GO:0002443 174 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
protein localization to organelle GO:0033365 185 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
regulation of cell cycle g2 m phase transition GO:1902749 10 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
cytoplasmic transport GO:0016482 234 0.012
receptor mediated endocytosis GO:0006898 51 0.012
homeostasis of number of cells GO:0048872 210 0.012
mapk cascade GO:0000165 281 0.012
establishment of spindle localization GO:0051293 19 0.012
regulation of mapk cascade GO:0043408 248 0.011
male sex differentiation GO:0046661 109 0.011
regulation of chromatin organization GO:1902275 57 0.011
regulation of dna recombination GO:0000018 34 0.011
dna integrity checkpoint GO:0031570 28 0.011
cellular homeostasis GO:0019725 240 0.011
rna processing GO:0006396 105 0.011
peptidyl threonine phosphorylation GO:0018107 31 0.011
endomembrane system organization GO:0010256 147 0.011
neuron migration GO:0001764 122 0.011
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.011
meiotic cell cycle checkpoint GO:0033313 2 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
spindle assembly involved in female meiosis i GO:0007057 2 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
regulation of protein processing GO:0070613 96 0.011
kinetochore organization GO:0051383 2 0.011
covalent chromatin modification GO:0016569 163 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
positive regulation of cell cycle process GO:0090068 61 0.011
regulation of sister chromatid cohesion GO:0007063 5 0.011
regulation of stem cell proliferation GO:0072091 78 0.010
negative regulation of mitotic metaphase anaphase transition GO:0045841 7 0.010
cation transport GO:0006812 399 0.010
anatomical structure homeostasis GO:0060249 145 0.010
single organism nuclear import GO:1902593 95 0.010
carbohydrate homeostasis GO:0033500 128 0.010
protein oligomerization GO:0051259 67 0.010
chromatin remodeling GO:0006338 32 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
cell maturation GO:0048469 127 0.010
synaptonemal complex assembly GO:0007130 13 0.010
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.010
lymphocyte differentiation GO:0030098 242 0.010
regulation of cellular component size GO:0032535 121 0.010

Cenpk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
thoracic cancer DOID:5093 0 0.038
cancer DOID:162 0 0.038
disease of cellular proliferation DOID:14566 0 0.038
organ system cancer DOID:0050686 0 0.038
immune system disease DOID:2914 0 0.018
disease of anatomical entity DOID:7 0 0.018
microcephaly DOID:10907 0 0.018
physical disorder DOID:0080015 0 0.018
congenital nervous system abnormality DOID:2490 0 0.018
hematopoietic system disease DOID:74 0 0.014
aplastic anemia DOID:12449 0 0.013
bone marrow disease DOID:4961 0 0.013
anemia DOID:2355 0 0.013
male reproductive organ cancer DOID:3856 0 0.011
reproductive organ cancer DOID:193 0 0.011
breast cancer DOID:1612 0 0.010