Mus musculus

27 known processes

Slc9a4

solute carrier family 9 (sodium/hydrogen exchanger), member 4

(Aliases: D730009J23Rik,AW990558,NHE4)

Slc9a4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.108
Mouse Worm
cation transport GO:0006812 399 0.099
Mouse Worm
cellular amino acid metabolic process GO:0006520 103 0.077
transmembrane transport GO:0055085 412 0.060
Mouse Worm
cation transmembrane transport GO:0098655 266 0.055
Mouse Worm
ras protein signal transduction GO:0007265 77 0.051
regulation of cellular amino acid metabolic process GO:0006521 5 0.050
inorganic cation transmembrane transport GO:0098662 207 0.050
Mouse Worm
g protein coupled receptor signaling pathway GO:0007186 243 0.049
purine ribonucleotide metabolic process GO:0009150 290 0.046
sodium ion transport GO:0006814 73 0.045
Mouse Worm
cellular amine metabolic process GO:0044106 44 0.045
cell adhesion GO:0007155 329 0.044
inorganic ion transmembrane transport GO:0098660 234 0.044
Mouse Worm
protein maturation GO:0051604 176 0.043
cellular lipid metabolic process GO:0044255 323 0.041
innate immune response GO:0045087 157 0.036
macromolecule catabolic process GO:0009057 281 0.036
Worm
cellular homeostasis GO:0019725 240 0.035
Worm
nucleotide metabolic process GO:0009117 332 0.034
cellular ketone metabolic process GO:0042180 84 0.034
regulation of cellular ketone metabolic process GO:0010565 66 0.032
locomotory behavior GO:0007626 195 0.031
skeletal system development GO:0001501 356 0.031
purine nucleotide metabolic process GO:0006163 302 0.030
cytokine production GO:0001816 319 0.030
response to organonitrogen compound GO:0010243 246 0.030
carbohydrate metabolic process GO:0005975 230 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
regulation of cellular amine metabolic process GO:0033238 20 0.029
nucleoside phosphate metabolic process GO:0006753 338 0.029
rho protein signal transduction GO:0007266 32 0.029
mapk cascade GO:0000165 281 0.028
carbohydrate derivative biosynthetic process GO:1901137 183 0.027
multicellular organismal signaling GO:0035637 91 0.026
forebrain development GO:0030900 302 0.026
regulation of organelle organization GO:0033043 289 0.026
nitrogen compound transport GO:0071705 271 0.026
Worm
regulation of hydrolase activity GO:0051336 246 0.026
amine metabolic process GO:0009308 45 0.026
hormone metabolic process GO:0042445 86 0.026
transmission of nerve impulse GO:0019226 76 0.025
cellular response to organonitrogen compound GO:0071417 145 0.025
ossification GO:0001503 216 0.025
ribonucleotide metabolic process GO:0009259 291 0.024
striated muscle tissue development GO:0014706 293 0.024
Mouse
extracellular matrix organization GO:0030198 147 0.024
action potential GO:0001508 78 0.024
aromatic compound catabolic process GO:0019439 286 0.024
regulation of membrane potential GO:0042391 192 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
purine containing compound metabolic process GO:0072521 311 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
respiratory system development GO:0060541 190 0.023
regulation of protein localization GO:0032880 231 0.023
regulation of secretion GO:0051046 274 0.023
immune effector process GO:0002252 321 0.023
cation homeostasis GO:0055080 212 0.022
Mouse Worm
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
regulation of cell motility GO:2000145 236 0.022
positive regulation of cell motility GO:2000147 116 0.022
sensory perception GO:0007600 245 0.022
oxidation reduction process GO:0055114 342 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
ear development GO:0043583 200 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
regulation of hormone levels GO:0010817 211 0.021
positive regulation of cell migration GO:0030335 109 0.021
regulation of cell projection organization GO:0031344 206 0.021
regulation of anatomical structure size GO:0090066 178 0.021
protein catabolic process GO:0030163 221 0.021
Worm
multicellular organismal homeostasis GO:0048871 164 0.021
epidermis development GO:0008544 187 0.021
skeletal system morphogenesis GO:0048705 203 0.021
ribose phosphate metabolic process GO:0019693 291 0.021
membrane organization GO:0061024 245 0.021
extracellular structure organization GO:0043062 148 0.021
activation of immune response GO:0002253 138 0.021
regulation of proteolysis GO:0030162 164 0.021
positive regulation of cell development GO:0010720 237 0.020
muscle cell differentiation GO:0042692 261 0.020
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
protein processing GO:0016485 163 0.019
neuronal action potential GO:0019228 54 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
actin cytoskeleton organization GO:0030036 220 0.019
peptidyl amino acid modification GO:0018193 336 0.019
reactive oxygen species metabolic process GO:0072593 84 0.019
positive regulation of cell death GO:0010942 224 0.019
cellular response to lipid GO:0071396 145 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
regulation of endopeptidase activity GO:0052548 89 0.018
anion transport GO:0006820 177 0.018
Worm
regulation of cytokine production GO:0001817 266 0.018
skin development GO:0043588 220 0.018
regulation of epithelial cell proliferation GO:0050678 141 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
negative regulation of growth GO:0045926 99 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
response to drug GO:0042493 75 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.017
amide transport GO:0042886 138 0.017
Worm
dna metabolic process GO:0006259 303 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
development of primary sexual characteristics GO:0045137 143 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
regulation of peptidase activity GO:0052547 96 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
regulation of cellular response to stress GO:0080135 159 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
organelle fission GO:0048285 170 0.016
tissue homeostasis GO:0001894 115 0.016
metal ion homeostasis GO:0055065 189 0.016
regulation of cell migration GO:0030334 219 0.016
sodium ion transmembrane transport GO:0035725 49 0.016
Mouse Worm
hormone secretion GO:0046879 128 0.016
regulation of peptide transport GO:0090087 91 0.016
Worm
regulation of metal ion transport GO:0010959 106 0.016
epithelial cell development GO:0002064 159 0.016
intracellular protein transport GO:0006886 204 0.016
urogenital system development GO:0001655 261 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
lung development GO:0030324 164 0.016
protein secretion GO:0009306 111 0.016
positive regulation of protein modification process GO:0031401 299 0.016
phospholipid metabolic process GO:0006644 87 0.015
regulation of mapk cascade GO:0043408 248 0.015
regulation of protein maturation GO:1903317 96 0.015
leukocyte activation involved in immune response GO:0002366 126 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
muscle system process GO:0003012 141 0.015
Worm
nucleoside triphosphate catabolic process GO:0009143 205 0.015
regulation of kinase activity GO:0043549 249 0.015
hexose metabolic process GO:0019318 98 0.015
regulation of system process GO:0044057 200 0.015
Worm
microtubule based process GO:0007017 236 0.015
cell activation involved in immune response GO:0002263 126 0.015
regulation of cell cycle process GO:0010564 160 0.015
chemotaxis GO:0006935 247 0.015
positive regulation of secretion GO:0051047 130 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
cellular response to organic cyclic compound GO:0071407 87 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
regulation of cytoskeleton organization GO:0051493 122 0.014
male gonad development GO:0008584 88 0.014
response to organic cyclic compound GO:0014070 198 0.014
regulation of protein catabolic process GO:0042176 108 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
response to lipopolysaccharide GO:0032496 128 0.014
defense response to other organism GO:0098542 197 0.014
male sex differentiation GO:0046661 109 0.014
mitotic cell cycle process GO:1903047 159 0.014
single organismal cell cell adhesion GO:0016337 131 0.014
regulation of ion transmembrane transport GO:0034765 119 0.014
positive regulation of cell projection organization GO:0031346 95 0.014
apoptotic signaling pathway GO:0097190 306 0.014
nucleoside catabolic process GO:0009164 206 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
regulation of transferase activity GO:0051338 263 0.014
regulation of cell growth GO:0001558 91 0.014
regulation of interleukin 10 secretion GO:2001179 4 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
cell growth GO:0016049 130 0.014
multi multicellular organism process GO:0044706 109 0.014
nucleotide catabolic process GO:0009166 217 0.014
cytoplasmic transport GO:0016482 234 0.014
regulation of protein processing GO:0070613 96 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
respiratory tube development GO:0030323 167 0.014
organic acid biosynthetic process GO:0016053 86 0.014
peptide transport GO:0015833 133 0.013
Worm
positive regulation of nervous system development GO:0051962 221 0.013
angiogenesis GO:0001525 201 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
positive regulation of protein transport GO:0051222 93 0.013
negative regulation of cell development GO:0010721 169 0.013
negative regulation of molecular function GO:0044092 258 0.013
steroid metabolic process GO:0008202 119 0.013
regulation of feeding behavior GO:0060259 3 0.013
Worm
purine nucleotide catabolic process GO:0006195 211 0.013
organic cyclic compound catabolic process GO:1901361 295 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
positive regulation of cytokine production GO:0001819 174 0.013
wound healing GO:0042060 157 0.013
purine ribonucleotide biosynthetic process GO:0009152 59 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
regulation of ion transport GO:0043269 215 0.013
Worm
positive regulation of transferase activity GO:0051347 167 0.013
response to sterol GO:0036314 4 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
placenta development GO:0001890 140 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
monosaccharide metabolic process GO:0005996 106 0.012
dephosphorylation GO:0016311 129 0.012
renal system development GO:0072001 225 0.012
axon ensheathment GO:0008366 76 0.012
mitotic cell cycle GO:0000278 195 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
heterocycle catabolic process GO:0046700 280 0.012
regulation of secretion by cell GO:1903530 249 0.012
purine nucleotide biosynthetic process GO:0006164 65 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.012
smoothened signaling pathway GO:0007224 105 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
genetic imprinting GO:0071514 27 0.012
potassium ion transmembrane transport GO:0071805 43 0.012
organelle assembly GO:0070925 177 0.012
adult behavior GO:0030534 135 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
protein ubiquitination GO:0016567 171 0.012
protein localization to membrane GO:0072657 108 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
defecation GO:0030421 1 0.012
Worm
nucleoside metabolic process GO:0009116 246 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
nuclear division GO:0000280 158 0.012
actin filament organization GO:0007015 113 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
lipid biosynthetic process GO:0008610 179 0.012
gland development GO:0048732 330 0.012
connective tissue development GO:0061448 179 0.012
regulation of protein transport GO:0051223 163 0.012
anion transmembrane transport GO:0098656 71 0.012
transepithelial chloride transport GO:0030321 4 0.012
positive regulation of cell activation GO:0050867 158 0.012
positive regulation of protein secretion GO:0050714 52 0.011
cell substrate adhesion GO:0031589 130 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
immune response activating signal transduction GO:0002757 116 0.011
peptide secretion GO:0002790 114 0.011
nuclear transport GO:0051169 139 0.011
peptide hormone secretion GO:0030072 109 0.011
protein localization to organelle GO:0033365 185 0.011
calcium ion transport GO:0006816 159 0.011
carboxylic acid transport GO:0046942 100 0.011
Worm
single organism cell adhesion GO:0098602 156 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
regulation of neuron differentiation GO:0045664 281 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
myeloid cell differentiation GO:0030099 233 0.011
epithelial cell proliferation GO:0050673 174 0.011
defense response to gram positive bacterium GO:0050830 50 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
regulation of response to wounding GO:1903034 189 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
immune response regulating signaling pathway GO:0002764 125 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
cellular chemical homeostasis GO:0055082 215 0.011
Worm
regulation of transmembrane transport GO:0034762 128 0.011
regulation of cell activation GO:0050865 289 0.011
lateral inhibition GO:0046331 1 0.011
interleukin 8 production GO:0032637 4 0.011
circulatory system process GO:0003013 197 0.011
fat cell differentiation GO:0045444 160 0.011
interleukin 10 secretion GO:0072608 4 0.011
digestion GO:0007586 40 0.011
positive regulation of proteolysis GO:0045862 85 0.010
nucleoside triphosphate metabolic process GO:0009141 230 0.010
cell division GO:0051301 120 0.010
negative regulation of cell proliferation GO:0008285 296 0.010
ear morphogenesis GO:0042471 118 0.010
blood circulation GO:0008015 195 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.010
cellular protein complex assembly GO:0043623 116 0.010
regulation of apoptotic signaling pathway GO:2001233 197 0.010
cytokine secretion GO:0050663 72 0.010
positive regulation of cell adhesion GO:0045785 80 0.010
regulation of nucleotide metabolic process GO:0006140 169 0.010
cellular response to dna damage stimulus GO:0006974 207 0.010
positive regulation of kinase activity GO:0033674 155 0.010
stem cell maintenance GO:0019827 130 0.010
endocytosis GO:0006897 168 0.010
energy derivation by oxidation of organic compounds GO:0015980 77 0.010
regulation of bmp signaling pathway GO:0030510 60 0.010
inflammatory response GO:0006954 244 0.010
transforming growth factor beta secretion GO:0038044 1 0.010

Slc9a4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016
disease of metabolism DOID:0014667 0 0.012
cardiovascular system disease DOID:1287 0 0.010