Mus musculus

63 known processes

Slc9a6

solute carrier family 9 (sodium/hydrogen exchanger), member 6

(Aliases: mKIAA0267,6430520C02Rik,3732426M05,NHE6)

Slc9a6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.066
ion transmembrane transport GO:0034220 361 0.063
membrane organization GO:0061024 245 0.063
nitrogen compound transport GO:0071705 271 0.056
transmembrane transport GO:0055085 412 0.054
cellular amine metabolic process GO:0044106 44 0.053
endocytosis GO:0006897 168 0.051
cellular lipid metabolic process GO:0044255 323 0.048
organic cyclic compound catabolic process GO:1901361 295 0.047
cation transport GO:0006812 399 0.046
cellular homeostasis GO:0019725 240 0.046
cation transmembrane transport GO:0098655 266 0.046
amine metabolic process GO:0009308 45 0.045
cation homeostasis GO:0055080 212 0.044
regulation of cellular amine metabolic process GO:0033238 20 0.043
nucleotide metabolic process GO:0009117 332 0.042
nucleobase containing small molecule metabolic process GO:0055086 352 0.042
positive regulation of cellular amine metabolic process GO:0033240 5 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.039
nucleoside metabolic process GO:0009116 246 0.038
heterocycle catabolic process GO:0046700 280 0.037
purine containing compound metabolic process GO:0072521 311 0.037
purine nucleoside triphosphate metabolic process GO:0009144 226 0.036
lipid biosynthetic process GO:0008610 179 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.034
cellular ketone metabolic process GO:0042180 84 0.034
regulation of cellular catabolic process GO:0031329 242 0.033
apoptotic signaling pathway GO:0097190 306 0.033
organophosphate catabolic process GO:0046434 232 0.033
exocytosis GO:0006887 121 0.032
ribonucleotide metabolic process GO:0009259 291 0.032
organonitrogen compound catabolic process GO:1901565 264 0.032
purine nucleoside triphosphate catabolic process GO:0009146 203 0.031
ribonucleoside triphosphate catabolic process GO:0009203 199 0.031
ribonucleoside catabolic process GO:0042454 206 0.031
anion transport GO:0006820 177 0.031
compound eye development GO:0048749 1 0.030
purine ribonucleotide metabolic process GO:0009150 290 0.030
aromatic compound catabolic process GO:0019439 286 0.030
mapk cascade GO:0000165 281 0.030
regulation of secretion GO:0051046 274 0.030
cellular chemical homeostasis GO:0055082 215 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.029
nucleoside triphosphate metabolic process GO:0009141 230 0.029
positive regulation of cell development GO:0010720 237 0.029
positive regulation of protein modification process GO:0031401 299 0.029
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.029
purine nucleoside metabolic process GO:0042278 241 0.029
regulation of secretion by cell GO:1903530 249 0.028
ribose phosphate metabolic process GO:0019693 291 0.028
regulation of transferase activity GO:0051338 263 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
regulation of neuron differentiation GO:0045664 281 0.028
ribonucleoside metabolic process GO:0009119 245 0.028
inorganic cation transmembrane transport GO:0098662 207 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.028
metal ion homeostasis GO:0055065 189 0.027
inorganic ion transmembrane transport GO:0098660 234 0.027
regulation of vesicle mediated transport GO:0060627 139 0.027
organelle localization GO:0051640 179 0.027
macromolecule catabolic process GO:0009057 281 0.026
glycerophospholipid metabolic process GO:0006650 71 0.026
lipid localization GO:0010876 126 0.026
cellular nitrogen compound catabolic process GO:0044270 280 0.026
divalent inorganic cation transport GO:0072511 178 0.025
glycosyl compound metabolic process GO:1901657 246 0.025
nucleoside catabolic process GO:0009164 206 0.024
camera type eye development GO:0043010 266 0.024
glycerolipid metabolic process GO:0046486 122 0.024
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.024
cellular metal ion homeostasis GO:0006875 151 0.024
multicellular organism growth GO:0035264 161 0.024
purine nucleoside catabolic process GO:0006152 205 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
leukocyte differentiation GO:0002521 342 0.023
response to oxidative stress GO:0006979 123 0.023
cytoplasmic transport GO:0016482 234 0.023
glycosyl compound catabolic process GO:1901658 206 0.023
regulation of ion transport GO:0043269 215 0.023
regulation of mapk cascade GO:0043408 248 0.023
organonitrogen compound biosynthetic process GO:1901566 192 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.022
maintenance of location GO:0051235 89 0.022
synaptic transmission GO:0007268 329 0.022
phospholipid metabolic process GO:0006644 87 0.022
purine ribonucleotide catabolic process GO:0009154 208 0.022
cellular ion homeostasis GO:0006873 165 0.022
transmission of nerve impulse GO:0019226 76 0.022
regulation of purine nucleotide metabolic process GO:1900542 169 0.022
regulation of cell projection organization GO:0031344 206 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
ribonucleoside triphosphate metabolic process GO:0009199 220 0.022
guanosine containing compound metabolic process GO:1901068 144 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
divalent metal ion transport GO:0070838 172 0.021
protein ubiquitination GO:0016567 171 0.021
organic hydroxy compound metabolic process GO:1901615 203 0.021
oxidation reduction process GO:0055114 342 0.021
regulation of lymphocyte activation GO:0051249 240 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
alcohol metabolic process GO:0006066 116 0.020
positive regulation of secretion GO:0051047 130 0.020
regulation of cell activation GO:0050865 289 0.020
response to radiation GO:0009314 165 0.020
regulation of neuron projection development GO:0010975 169 0.020
lipid transport GO:0006869 98 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
forebrain development GO:0030900 302 0.019
cellular divalent inorganic cation homeostasis GO:0072503 127 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
regulation of homeostatic process GO:0032844 182 0.019
mitochondrion organization GO:0007005 134 0.019
positive regulation of mapk cascade GO:0043410 170 0.019
regulation of exocytosis GO:0017157 61 0.018
regulation of cell motility GO:2000145 236 0.018
organic anion transport GO:0015711 137 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
response to organic cyclic compound GO:0014070 198 0.018
carboxylic acid biosynthetic process GO:0046394 86 0.018
negative regulation of immune system process GO:0002683 209 0.018
regulation of kinase activity GO:0043549 249 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.018
divalent inorganic cation homeostasis GO:0072507 138 0.018
positive regulation of nervous system development GO:0051962 221 0.018
organic acid transport GO:0015849 101 0.018
microtubule based process GO:0007017 236 0.018
guanosine containing compound catabolic process GO:1901069 144 0.018
protein modification by small protein conjugation GO:0032446 187 0.017
regulation of protein kinase activity GO:0045859 232 0.017
axonogenesis GO:0007409 274 0.017
Human
intracellular protein transport GO:0006886 204 0.017
nucleotide catabolic process GO:0009166 217 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
regulation of protein localization GO:0032880 231 0.017
cell type specific apoptotic process GO:0097285 268 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
ras protein signal transduction GO:0007265 77 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.017
endomembrane system organization GO:0010256 147 0.017
positive regulation of secretion by cell GO:1903532 114 0.017
small molecule biosynthetic process GO:0044283 132 0.017
calcium ion transport GO:0006816 159 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
multicellular organismal signaling GO:0035637 91 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
immune effector process GO:0002252 321 0.016
lymphocyte differentiation GO:0030098 242 0.016
regulation of hydrolase activity GO:0051336 246 0.016
purine containing compound catabolic process GO:0072523 213 0.016
regulation of membrane potential GO:0042391 192 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
carbohydrate metabolic process GO:0005975 230 0.016
response to organonitrogen compound GO:0010243 246 0.016
cellular protein catabolic process GO:0044257 155 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
synapse organization GO:0050808 125 0.016
hormone secretion GO:0046879 128 0.016
gtp metabolic process GO:0046039 144 0.016
negative regulation of nervous system development GO:0051961 156 0.016
amide transport GO:0042886 138 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
skeletal system development GO:0001501 356 0.016
cellular calcium ion homeostasis GO:0006874 119 0.016
calcium ion homeostasis GO:0055074 127 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
wound healing GO:0042060 157 0.016
inflammatory response GO:0006954 244 0.016
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.016
retina development in camera type eye GO:0060041 119 0.016
regulation of t cell activation GO:0050863 170 0.016
sterol transport GO:0015918 38 0.016
positive regulation of protein kinase activity GO:0045860 144 0.015
response to inorganic substance GO:0010035 96 0.015
negative regulation of molecular function GO:0044092 258 0.015
action potential GO:0001508 78 0.015
rho protein signal transduction GO:0007266 32 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
peptidyl amino acid modification GO:0018193 336 0.015
protein modification by small protein conjugation or removal GO:0070647 207 0.015
regulation of hormone levels GO:0010817 211 0.015
protein localization to organelle GO:0033365 185 0.015
regulation of organelle organization GO:0033043 289 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
cellular response to biotic stimulus GO:0071216 92 0.015
cell growth GO:0016049 130 0.014
Human
regionalization GO:0003002 337 0.014
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.014
homeostasis of number of cells GO:0048872 210 0.014
protein catabolic process GO:0030163 221 0.014
positive regulation of transferase activity GO:0051347 167 0.014
protein targeting GO:0006605 143 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
peptide secretion GO:0002790 114 0.014
gland development GO:0048732 330 0.014
phagocytosis GO:0006909 66 0.014
leukocyte mediated immunity GO:0002443 174 0.014
adult behavior GO:0030534 135 0.014
protein targeting to vacuole GO:0006623 3 0.014
response to light stimulus GO:0009416 135 0.014
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.014
regulation of cell migration GO:0030334 219 0.014
blood circulation GO:0008015 195 0.014
negative regulation of synapse assembly GO:0051964 3 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
positive regulation of neuron differentiation GO:0045666 141 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
lateral inhibition GO:0046331 1 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
response to extracellular stimulus GO:0009991 127 0.014
transition metal ion homeostasis GO:0055076 54 0.014
neuronal action potential GO:0019228 54 0.014
spermatogenesis GO:0007283 284 0.014
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
cognition GO:0050890 149 0.013
regulation of cell growth GO:0001558 91 0.013
dendrite development GO:0016358 115 0.013
regulation of body fluid levels GO:0050878 162 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
anion transmembrane transport GO:0098656 71 0.013
locomotory behavior GO:0007626 195 0.013
establishment of organelle localization GO:0051656 122 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
sulfur compound metabolic process GO:0006790 100 0.013
positive regulation of nucleotide catabolic process GO:0030813 88 0.013
negative regulation of lymphocyte activation GO:0051250 91 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.013
developmental maturation GO:0021700 193 0.013
muscle tissue development GO:0060537 308 0.013
peptide hormone secretion GO:0030072 109 0.013
negative regulation of growth GO:0045926 99 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.013
retrograde transport endosome to golgi GO:0042147 2 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
cellular response to organonitrogen compound GO:0071417 145 0.012
regulation of lymphocyte mediated immunity GO:0002706 84 0.012
regulation of myeloid cell differentiation GO:0045637 96 0.012
innate immune response GO:0045087 157 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
regulation of ossification GO:0030278 112 0.012
negative regulation of cell activation GO:0050866 111 0.012
gtp catabolic process GO:0006184 143 0.012
t cell activation GO:0042110 289 0.012
regulation of defense response GO:0031347 233 0.012
negative regulation of cell development GO:0010721 169 0.012
sensory organ morphogenesis GO:0090596 242 0.012
regulation of intracellular transport GO:0032386 159 0.012
myeloid cell homeostasis GO:0002262 114 0.012
regulation of proteolysis GO:0030162 164 0.012
male gamete generation GO:0048232 285 0.012
response to peptide GO:1901652 136 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
myeloid cell differentiation GO:0030099 233 0.012
regulation of anatomical structure size GO:0090066 178 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
regulation of cellular response to stress GO:0080135 159 0.012
cellular transition metal ion homeostasis GO:0046916 32 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
positive regulation of kinase activity GO:0033674 155 0.012
b cell activation GO:0042113 161 0.012
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.012
protein processing GO:0016485 163 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
organic hydroxy compound transport GO:0015850 93 0.011
sequestering of metal ion GO:0051238 19 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
leukocyte proliferation GO:0070661 172 0.011
sensory perception GO:0007600 245 0.011
response to insulin GO:0032868 100 0.011
protein localization to membrane GO:0072657 108 0.011
organic hydroxy compound biosynthetic process GO:1901617 77 0.011
peptide transport GO:0015833 133 0.011
renal system development GO:0072001 225 0.011
positive regulation of cell death GO:0010942 224 0.011
defense response to bacterium GO:0042742 119 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
carboxylic acid transport GO:0046942 100 0.011
transition metal ion transport GO:0000041 38 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
cytokine production GO:0001816 319 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
striated muscle tissue development GO:0014706 293 0.011
nuclear transport GO:0051169 139 0.011
cellular response to lipid GO:0071396 145 0.011
protein maturation GO:0051604 176 0.011
fat cell differentiation GO:0045444 160 0.011
protein localization to vacuole GO:0072665 4 0.011
organic acid biosynthetic process GO:0016053 86 0.011
anatomical structure homeostasis GO:0060249 145 0.011
sphingolipid biosynthetic process GO:0030148 26 0.011
fatty acid metabolic process GO:0006631 121 0.011
positive regulation of homeostatic process GO:0032846 64 0.011
positive regulation of gtp catabolic process GO:0033126 85 0.011
cellular response to oxidative stress GO:0034599 76 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
muscle system process GO:0003012 141 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
circulatory system process GO:0003013 197 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
stem cell development GO:0048864 219 0.011
establishment of vesicle localization GO:0051650 81 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
negative regulation of phosphorylation GO:0042326 166 0.010
rna processing GO:0006396 105 0.010
response to osmotic stress GO:0006970 21 0.010
response to growth factor GO:0070848 198 0.010
regulation of cytokine production GO:0001817 266 0.010
positive regulation of camp mediated signaling GO:0043950 3 0.010
sterol metabolic process GO:0016125 58 0.010
regulation of transmembrane transport GO:0034762 128 0.010
regulation of leukocyte mediated immunity GO:0002703 104 0.010
canonical wnt signaling pathway GO:0060070 130 0.010
carbohydrate derivative biosynthetic process GO:1901137 183 0.010
response to peptide hormone GO:0043434 127 0.010
bmp signaling pathway GO:0030509 93 0.010
plasma membrane organization GO:0007009 90 0.010
retrograde vesicle mediated transport golgi to er GO:0006890 1 0.010
positive regulation of neuron projection development GO:0010976 79 0.010
wnt signaling pathway GO:0016055 188 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
regulation of gtp catabolic process GO:0033124 113 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
response to epidermal growth factor GO:0070849 4 0.010
regulation of leukocyte proliferation GO:0070663 121 0.010
sequestering of calcium ion GO:0051208 18 0.010
insulin secretion GO:0030073 89 0.010
chemotaxis GO:0006935 247 0.010
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.010

Slc9a6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.079
nervous system disease DOID:863 0 0.079
central nervous system disease DOID:331 0 0.033
disease of metabolism DOID:0014667 0 0.015
brain disease DOID:936 0 0.012
inherited metabolic disorder DOID:655 0 0.011
neuropathy DOID:870 0 0.011
musculoskeletal system disease DOID:17 0 0.010