Mus musculus

33 known processes

Slc9a2

solute carrier family 9 (sodium/hydrogen exchanger), member 2

(Aliases: 4932415O19Rik,MGC124410,MGC124408,2210416H12Rik,AV333884,NHE2)

Slc9a2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.118
cation transport GO:0006812 399 0.084
ion transmembrane transport GO:0034220 361 0.083
amine metabolic process GO:0009308 45 0.078
transmembrane transport GO:0055085 412 0.066
cellular ketone metabolic process GO:0042180 84 0.066
cellular amine metabolic process GO:0044106 44 0.063
regulation of cellular amino acid metabolic process GO:0006521 5 0.058
regulation of cellular ketone metabolic process GO:0010565 66 0.056
regulation of cellular amine metabolic process GO:0033238 20 0.053
neuronal action potential GO:0019228 54 0.050
nitrogen compound transport GO:0071705 271 0.050
Worm
cation transmembrane transport GO:0098655 266 0.050
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
inorganic ion transmembrane transport GO:0098660 234 0.048
regulation of membrane potential GO:0042391 192 0.047
positive regulation of cellular amine metabolic process GO:0033240 5 0.047
nucleobase containing small molecule metabolic process GO:0055086 352 0.046
multicellular organismal signaling GO:0035637 91 0.043
inorganic cation transmembrane transport GO:0098662 207 0.042
purine ribonucleotide metabolic process GO:0009150 290 0.041
carboxylic acid transport GO:0046942 100 0.041
Worm
nucleoside phosphate metabolic process GO:0006753 338 0.038
transmission of nerve impulse GO:0019226 76 0.038
anion transport GO:0006820 177 0.037
Worm
purine containing compound metabolic process GO:0072521 311 0.037
peptidyl amino acid modification GO:0018193 336 0.037
ras protein signal transduction GO:0007265 77 0.037
cellular lipid metabolic process GO:0044255 323 0.037
g protein coupled receptor signaling pathway GO:0007186 243 0.036
ribonucleotide metabolic process GO:0009259 291 0.034
cellular homeostasis GO:0019725 240 0.034
Worm
aromatic compound catabolic process GO:0019439 286 0.034
nucleoside metabolic process GO:0009116 246 0.033
organic anion transport GO:0015711 137 0.033
Worm
small gtpase mediated signal transduction GO:0007264 97 0.033
carbohydrate derivative catabolic process GO:1901136 231 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.032
ribonucleoside metabolic process GO:0009119 245 0.031
ribose phosphate metabolic process GO:0019693 291 0.031
heterocycle catabolic process GO:0046700 280 0.031
leukocyte differentiation GO:0002521 342 0.030
regulation of ion transmembrane transport GO:0034765 119 0.030
male gamete generation GO:0048232 285 0.030
purine nucleotide metabolic process GO:0006163 302 0.029
purine nucleotide catabolic process GO:0006195 211 0.029
positive regulation of protein modification process GO:0031401 299 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.028
regulation of secretion GO:0051046 274 0.028
regulation of cellular catabolic process GO:0031329 242 0.028
organic cyclic compound catabolic process GO:1901361 295 0.028
monocarboxylic acid metabolic process GO:0032787 191 0.028
metal ion homeostasis GO:0055065 189 0.027
action potential GO:0001508 78 0.027
cytoplasmic transport GO:0016482 234 0.027
regulation of ion transport GO:0043269 215 0.027
Worm
cation homeostasis GO:0055080 212 0.027
cell adhesion GO:0007155 329 0.026
cellular nitrogen compound catabolic process GO:0044270 280 0.026
regulation of transmembrane transport GO:0034762 128 0.026
carbohydrate metabolic process GO:0005975 230 0.026
nucleotide metabolic process GO:0009117 332 0.026
spermatogenesis GO:0007283 284 0.026
synaptic transmission GO:0007268 329 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
positive regulation of protein phosphorylation GO:0001934 242 0.026
oxidation reduction process GO:0055114 342 0.026
nucleoside triphosphate metabolic process GO:0009141 230 0.026
regulation of lymphocyte activation GO:0051249 240 0.026
purine containing compound catabolic process GO:0072523 213 0.025
purine nucleoside metabolic process GO:0042278 241 0.025
carbohydrate derivative biosynthetic process GO:1901137 183 0.025
negative regulation of phosphorus metabolic process GO:0010563 184 0.025
adult behavior GO:0030534 135 0.025
regulation of anatomical structure size GO:0090066 178 0.025
negative regulation of molecular function GO:0044092 258 0.024
organophosphate catabolic process GO:0046434 232 0.024
regulation of secretion by cell GO:1903530 249 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
regulation of hormone levels GO:0010817 211 0.024
response to organonitrogen compound GO:0010243 246 0.023
regulation of cell motility GO:2000145 236 0.023
immune effector process GO:0002252 321 0.023
mapk cascade GO:0000165 281 0.023
apoptotic signaling pathway GO:0097190 306 0.023
regulation of cell projection organization GO:0031344 206 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
cellular chemical homeostasis GO:0055082 215 0.023
Worm
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
macromolecule catabolic process GO:0009057 281 0.023
Worm
purine ribonucleotide catabolic process GO:0009154 208 0.023
developmental maturation GO:0021700 193 0.023
cellular ion homeostasis GO:0006873 165 0.022
Worm
blood circulation GO:0008015 195 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
organonitrogen compound biosynthetic process GO:1901566 192 0.022
glycosyl compound metabolic process GO:1901657 246 0.022
organic hydroxy compound metabolic process GO:1901615 203 0.022
positive regulation of cellular catabolic process GO:0031331 148 0.022
regulation of neuron differentiation GO:0045664 281 0.022
circulatory system process GO:0003013 197 0.022
response to organic cyclic compound GO:0014070 198 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
organophosphate biosynthetic process GO:0090407 122 0.021
regulation of cell migration GO:0030334 219 0.021
regulation of cell activation GO:0050865 289 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
negative regulation of immune system process GO:0002683 209 0.021
regulation of hydrolase activity GO:0051336 246 0.021
lymphocyte differentiation GO:0030098 242 0.021
t cell activation GO:0042110 289 0.021
cellular metal ion homeostasis GO:0006875 151 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.021
fertilization GO:0009566 127 0.020
nucleotide catabolic process GO:0009166 217 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
muscle system process GO:0003012 141 0.020
Worm
skeletal system development GO:0001501 356 0.020
camera type eye development GO:0043010 266 0.020
cellular divalent inorganic cation homeostasis GO:0072503 127 0.020
cellular calcium ion homeostasis GO:0006874 119 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
regulation of protein localization GO:0032880 231 0.020
fat cell differentiation GO:0045444 160 0.020
small molecule biosynthetic process GO:0044283 132 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
gland development GO:0048732 330 0.020
nucleoside catabolic process GO:0009164 206 0.019
sequestering of calcium ion GO:0051208 18 0.019
calcium ion homeostasis GO:0055074 127 0.019
striated muscle tissue development GO:0014706 293 0.019
Mouse
organic acid transport GO:0015849 101 0.019
Worm
rho protein signal transduction GO:0007266 32 0.019
purine nucleoside triphosphate catabolic process GO:0009146 203 0.019
regulation of cell adhesion GO:0030155 154 0.019
germ cell development GO:0007281 185 0.019
epithelial cell development GO:0002064 159 0.019
Mouse
protein catabolic process GO:0030163 221 0.019
Worm
cell type specific apoptotic process GO:0097285 268 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
dna metabolic process GO:0006259 303 0.018
renal system development GO:0072001 225 0.018
adaptive immune response GO:0002250 155 0.018
muscle tissue development GO:0060537 308 0.018
Mouse
intracellular protein transport GO:0006886 204 0.018
wnt signaling pathway GO:0016055 188 0.018
maintenance of location GO:0051235 89 0.018
Worm
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
regulation of organelle organization GO:0033043 289 0.018
divalent inorganic cation transport GO:0072511 178 0.018
divalent inorganic cation homeostasis GO:0072507 138 0.018
cellular response to lipid GO:0071396 145 0.018
protein localization to organelle GO:0033365 185 0.018
cellular macromolecule catabolic process GO:0044265 206 0.017
forebrain development GO:0030900 302 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
alcohol metabolic process GO:0006066 116 0.017
regulation of protein transport GO:0051223 163 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
regulation of metal ion transport GO:0010959 106 0.017
ossification GO:0001503 216 0.017
sensory perception GO:0007600 245 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
spermatid differentiation GO:0048515 115 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
regulation of proteolysis GO:0030162 164 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.017
axon ensheathment GO:0008366 76 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
regulation of transferase activity GO:0051338 263 0.017
negative regulation of protein metabolic process GO:0051248 282 0.016
angiogenesis GO:0001525 201 0.016
microtubule based process GO:0007017 236 0.016
regulation of mapk cascade GO:0043408 248 0.016
positive regulation of cell activation GO:0050867 158 0.016
regulation of kinase activity GO:0043549 249 0.016
response to lipopolysaccharide GO:0032496 128 0.016
regulation of cell cycle GO:0051726 281 0.016
cellular protein complex assembly GO:0043623 116 0.016
response to acid chemical GO:0001101 111 0.016
membrane organization GO:0061024 245 0.016
regulation of t cell activation GO:0050863 170 0.016
regulation of leukocyte differentiation GO:1902105 159 0.016
spermatid development GO:0007286 108 0.016
cytokine production GO:0001816 319 0.016
amide transport GO:0042886 138 0.016
Worm
blood vessel morphogenesis GO:0048514 285 0.016
urogenital system development GO:0001655 261 0.016
cell maturation GO:0048469 127 0.015
multicellular organism growth GO:0035264 161 0.015
Worm
positive regulation of nucleotide metabolic process GO:0045981 114 0.015
regulation of system process GO:0044057 200 0.015
Worm
cellular response to organonitrogen compound GO:0071417 145 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
digestive system development GO:0055123 200 0.015
sulfur compound metabolic process GO:0006790 100 0.015
positive regulation of cell development GO:0010720 237 0.015
meiotic cell cycle GO:0051321 122 0.015
cellular response to acid chemical GO:0071229 68 0.015
protein maturation GO:0051604 176 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
lipid transport GO:0006869 98 0.015
Worm
ameboidal type cell migration GO:0001667 128 0.015
sodium ion transport GO:0006814 73 0.015
tissue homeostasis GO:0001894 115 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
regulation of ras protein signal transduction GO:0046578 114 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
lateral inhibition GO:0046331 1 0.015
skeletal muscle organ development GO:0060538 163 0.015
protein targeting GO:0006605 143 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
regulation of chloride transport GO:2001225 2 0.015
nucleotide biosynthetic process GO:0009165 78 0.015
sequestering of metal ion GO:0051238 19 0.015
plasma membrane organization GO:0007009 90 0.015
nuclear division GO:0000280 158 0.015
hexose metabolic process GO:0019318 98 0.015
protein modification by small protein conjugation or removal GO:0070647 207 0.015
peptidyl tyrosine modification GO:0018212 145 0.014
epithelial cell proliferation GO:0050673 174 0.014
ribonucleotide biosynthetic process GO:0009260 59 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
adult locomotory behavior GO:0008344 91 0.014
muscle cell differentiation GO:0042692 261 0.014
Mouse
dephosphorylation GO:0016311 129 0.014
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.014
peptidyl serine modification GO:0018209 83 0.014
leukocyte proliferation GO:0070661 172 0.014
ensheathment of neurons GO:0007272 76 0.014
glycoprotein metabolic process GO:0009100 116 0.014
generation of precursor metabolites and energy GO:0006091 103 0.014
peptide transport GO:0015833 133 0.014
Worm
anion transmembrane transport GO:0098656 71 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.014
hormone metabolic process GO:0042445 86 0.014
wound healing GO:0042060 157 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
mitotic cell cycle GO:0000278 195 0.014
nuclear transport GO:0051169 139 0.014
organelle fission GO:0048285 170 0.014
fatty acid metabolic process GO:0006631 121 0.014
tissue remodeling GO:0048771 102 0.013
myelination GO:0042552 74 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
negative regulation of protein modification process GO:0031400 163 0.013
alpha beta t cell differentiation GO:0046632 69 0.013
myeloid cell differentiation GO:0030099 233 0.013
protein processing GO:0016485 163 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
developmental growth involved in morphogenesis GO:0060560 138 0.013
muscle contraction GO:0006936 101 0.013
Worm
epithelial tube morphogenesis GO:0060562 303 0.013
lipid biosynthetic process GO:0008610 179 0.013
response to radiation GO:0009314 165 0.013
regulation of cell cycle process GO:0010564 160 0.013
negative regulation of cell development GO:0010721 169 0.013
heart morphogenesis GO:0003007 178 0.013
t cell differentiation GO:0030217 174 0.013
divalent metal ion transport GO:0070838 172 0.013
anatomical structure homeostasis GO:0060249 145 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
l amino acid transport GO:0015807 32 0.012
cell fate commitment GO:0045165 210 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
response to growth factor GO:0070848 198 0.012
protein ubiquitination GO:0016567 171 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
placenta development GO:0001890 140 0.012
nucleoside phosphate biosynthetic process GO:1901293 79 0.012
regulation of protein catabolic process GO:0042176 108 0.012
multi multicellular organism process GO:0044706 109 0.012
regulation of protein kinase activity GO:0045859 232 0.012
monocarboxylic acid transport GO:0015718 44 0.012
Worm
cellular response to growth factor stimulus GO:0071363 197 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
cell activation involved in immune response GO:0002263 126 0.012
regulation of ossification GO:0030278 112 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
cellular modified amino acid metabolic process GO:0006575 63 0.012
muscle cell development GO:0055001 133 0.012
cytosolic calcium ion homeostasis GO:0051480 70 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
potassium ion transport GO:0006813 52 0.012
defecation GO:0030421 1 0.012
Worm
regulation of body fluid levels GO:0050878 162 0.012
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.012
positive regulation of nucleotide catabolic process GO:0030813 88 0.012
dorsal ventral axon guidance GO:0033563 3 0.012
development of primary sexual characteristics GO:0045137 143 0.012
protein localization to nucleus GO:0034504 121 0.012
monosaccharide transport GO:0015749 58 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
leukocyte migration GO:0050900 124 0.012
myotube differentiation GO:0014902 105 0.012
locomotory behavior GO:0007626 195 0.012
carbohydrate transport GO:0008643 62 0.012
transepithelial chloride transport GO:0030321 4 0.012
second messenger mediated signaling GO:0019932 73 0.012
innate immune response GO:0045087 157 0.012
digestive tract development GO:0048565 190 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
epidermis development GO:0008544 187 0.011
hormone secretion GO:0046879 128 0.011
homeostasis of number of cells GO:0048872 210 0.011
mitotic cell cycle process GO:1903047 159 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
response to transforming growth factor beta GO:0071559 88 0.011
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.011
mesodermal cell migration GO:0008078 4 0.011
skin development GO:0043588 220 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
peptide secretion GO:0002790 114 0.011
small molecule catabolic process GO:0044282 71 0.011
regulation of cellular component size GO:0032535 121 0.011
rna interference GO:0016246 2 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
cellular response to organic cyclic compound GO:0071407 87 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
cell growth GO:0016049 130 0.011
epithelial tube formation GO:0072175 130 0.011
regulation of binding GO:0051098 111 0.011
rna processing GO:0006396 105 0.011
meiotic nuclear division GO:0007126 115 0.011
glucose transport GO:0015758 56 0.011
lipid localization GO:0010876 126 0.011
Worm
biomineral tissue development GO:0031214 64 0.011
compound eye development GO:0048749 1 0.011
intracellular mrna localization GO:0008298 4 0.011
protein glycosylation GO:0006486 55 0.011
regulation of response to wounding GO:1903034 189 0.011
response to light stimulus GO:0009416 135 0.011
steroid metabolic process GO:0008202 119 0.011
peptide hormone secretion GO:0030072 109 0.011
response to inorganic substance GO:0010035 96 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
sodium ion transmembrane transport GO:0035725 49 0.011
regionalization GO:0003002 337 0.011
gtp catabolic process GO:0006184 143 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.011
cellular protein catabolic process GO:0044257 155 0.011
hexose transport GO:0008645 56 0.011
lipoprotein metabolic process GO:0042157 43 0.011
positive regulation of vasoconstriction GO:0045907 4 0.011
meiotic cell cycle process GO:1903046 77 0.011
carbohydrate catabolic process GO:0016052 32 0.011
cell junction organization GO:0034330 77 0.011
lymphocyte proliferation GO:0046651 164 0.011
regulation of neuron projection development GO:0010975 169 0.011
calcium ion transport GO:0006816 159 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.010
microtubule cytoskeleton organization GO:0000226 157 0.010
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.010
actin filament based movement GO:0030048 23 0.010
actin mediated cell contraction GO:0070252 15 0.010
positive regulation of epithelial cell proliferation GO:0050679 68 0.010
lymphocyte mediated immunity GO:0002449 139 0.010
cofactor metabolic process GO:0051186 80 0.010
amino acid transmembrane transport GO:0003333 37 0.010
negative regulation of growth GO:0045926 99 0.010
purine nucleotide biosynthetic process GO:0006164 65 0.010
regulation of protein complex assembly GO:0043254 83 0.010
epithelial cell morphogenesis GO:0003382 41 0.010
oocyte construction GO:0007308 2 0.010
oocyte axis specification GO:0007309 2 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
actin cytoskeleton organization GO:0030036 220 0.010
single organism cell adhesion GO:0098602 156 0.010
lymphocyte activation involved in immune response GO:0002285 93 0.010
regulation of lymphocyte differentiation GO:0045619 107 0.010
bone development GO:0060348 120 0.010
peptidyl serine phosphorylation GO:0018105 74 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.010
ribonucleoside monophosphate metabolic process GO:0009161 80 0.010
mrna metabolic process GO:0016071 84 0.010
single fertilization GO:0007338 82 0.010
regulation of peptide transport GO:0090087 91 0.010
Worm
regulation of organ morphogenesis GO:2000027 144 0.010
ribose phosphate biosynthetic process GO:0046390 59 0.010
negative regulation of synapse assembly GO:0051964 3 0.010
neuron apoptotic process GO:0051402 142 0.010
alpha beta t cell activation GO:0046631 91 0.010
organic hydroxy compound transport GO:0015850 93 0.010

Slc9a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
cardiovascular system disease DOID:1287 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.013
musculoskeletal system disease DOID:17 0 0.013
organ system cancer DOID:0050686 0 0.012
sensory system disease DOID:0050155 0 0.011
central nervous system disease DOID:331 0 0.011