Mus musculus

36 known processes

Ddx58

DEAD (Asp-Glu-Ala-Asp) box polypeptide 58

(Aliases: RIG-I,C330021E21,6430573D20Rik)

Ddx58 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
viral process GO:0016032 41 0.990
Mouse
interspecies interaction between organisms GO:0044419 83 0.949
Mouse
negative regulation of multi organism process GO:0043901 68 0.947
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.830
Mouse
negative regulation of viral process GO:0048525 23 0.819
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.805
innate immune response GO:0045087 157 0.739
regulation of interferon beta production GO:0032648 13 0.727
negative regulation of viral entry into host cell GO:0046597 10 0.691
negative regulation of viral genome replication GO:0045071 10 0.676
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.669
Mouse
interferon beta production GO:0032608 16 0.657
regulation of innate immune response GO:0045088 91 0.649
Human Mouse
viral entry into host cell GO:0046718 15 0.619
entry into host cell GO:0030260 15 0.597
regulation of multi organism process GO:0043900 111 0.565
Human Mouse
regulation of viral entry into host cell GO:0046596 12 0.561
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.544
viral release from host cell GO:0019076 6 0.538
regulation of viral release from host cell GO:1902186 6 0.529
negative regulation of viral release from host cell GO:1902187 6 0.508
activation of innate immune response GO:0002218 56 0.508
Human Mouse
movement in environment of other organism involved in symbiotic interaction GO:0052192 15 0.496
protein modification by small protein conjugation or removal GO:0070647 207 0.476
protein modification by small protein conjugation GO:0032446 187 0.474
positive regulation of type i interferon production GO:0032481 14 0.462
regulation of cytokine production GO:0001817 266 0.370
immune effector process GO:0002252 321 0.368
Human Mouse
viral life cycle GO:0019058 36 0.303
Mouse
movement in host environment GO:0052126 15 0.275
nucleoside phosphate metabolic process GO:0006753 338 0.259
Worm
rig i signaling pathway GO:0039529 4 0.258
Human Mouse
regulation of defense response GO:0031347 233 0.249
Human Mouse
viral genome replication GO:0019079 17 0.232
Mouse
positive regulation of innate immune response GO:0045089 80 0.231
Human Mouse
defense response to virus GO:0051607 68 0.216
Human Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.206
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.197
response to vitamin d GO:0033280 3 0.158
protein ubiquitination GO:0016567 171 0.157
response to organic cyclic compound GO:0014070 198 0.155
macromolecule catabolic process GO:0009057 281 0.146
viral gene expression GO:0019080 3 0.145
positive regulation of viral entry into host cell GO:0046598 3 0.143
positive regulation of viral genome replication GO:0045070 2 0.141
regulation of type i interferon production GO:0032479 22 0.134
positive regulation of interferon beta production GO:0032728 8 0.124
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.122
purine containing compound metabolic process GO:0072521 311 0.121
Worm
dna metabolic process GO:0006259 303 0.115
heterocycle catabolic process GO:0046700 280 0.108
Worm
nucleoside phosphate catabolic process GO:1901292 222 0.107
Worm
i kappab kinase nf kappab signaling GO:0007249 85 0.102
organic cyclic compound catabolic process GO:1901361 295 0.100
Worm
purine containing compound catabolic process GO:0072523 213 0.099
Worm
ribonucleoside catabolic process GO:0042454 206 0.099
Worm
organonitrogen compound catabolic process GO:1901565 264 0.093
Worm
pattern recognition receptor signaling pathway GO:0002221 47 0.091
Human Mouse
purine nucleoside catabolic process GO:0006152 205 0.091
Worm
nucleoside metabolic process GO:0009116 246 0.086
Worm
cytokine production GO:0001816 319 0.086
negative regulation of defense response GO:0031348 77 0.084
Mouse
entry into other organism involved in symbiotic interaction GO:0051828 15 0.084
glycosyl compound metabolic process GO:1901657 246 0.083
Worm
defense response to other organism GO:0098542 197 0.082
Human Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.082
regulation of rig i signaling pathway GO:0039535 2 0.082
Mouse
negative regulation of cellular component organization GO:0051129 194 0.082
positive regulation of actin nucleation GO:0051127 3 0.081
negative regulation of cell proliferation GO:0008285 296 0.079
Mouse
activation of immune response GO:0002253 138 0.079
Human Mouse
regulation of response to biotic stimulus GO:0002831 38 0.078
Human Mouse
cell division GO:0051301 120 0.077
Mouse
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 4 0.075
Human Mouse
carbohydrate metabolic process GO:0005975 230 0.075
cellular macromolecule catabolic process GO:0044265 206 0.073
response to type i interferon GO:0034340 12 0.072
regulation of mapk cascade GO:0043408 248 0.072
purine nucleoside triphosphate metabolic process GO:0009144 226 0.070
Worm
regulation of interferon beta biosynthetic process GO:0045357 4 0.069
entry into host GO:0044409 15 0.068
rna catabolic process GO:0006401 29 0.068
regulation of defense response to virus GO:0050688 18 0.067
Human Mouse
nucleotide catabolic process GO:0009166 217 0.067
Worm
spleen development GO:0048536 39 0.067
Mouse
protein catabolic process GO:0030163 221 0.066
cellular nitrogen compound catabolic process GO:0044270 280 0.066
Worm
positive regulation of rig i signaling pathway GO:1900246 1 0.065
Mouse
protein polyubiquitination GO:0000209 33 0.065
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.063
regulation of hydrolase activity GO:0051336 246 0.062
regulation of cell activation GO:0050865 289 0.062
ribose phosphate metabolic process GO:0019693 291 0.060
Worm
purine nucleotide metabolic process GO:0006163 302 0.059
Worm
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.058
response to dsrna GO:0043331 30 0.057
positive regulation of programmed cell death GO:0043068 218 0.056
cell adhesion GO:0007155 329 0.056
positive regulation of mapk cascade GO:0043410 170 0.056
aromatic compound catabolic process GO:0019439 286 0.055
Worm
regulation of actin nucleation GO:0051125 4 0.055
cellular response to interferon alpha GO:0035457 4 0.054
cellular response to lipopolysaccharide GO:0071222 77 0.054
myeloid cell differentiation GO:0030099 233 0.053
regulation of protein catabolic process GO:0042176 108 0.051
modification dependent protein catabolic process GO:0019941 133 0.050
cellular response to cytokine stimulus GO:0071345 189 0.050
immune response regulating signaling pathway GO:0002764 125 0.049
Human Mouse
regulation of viral transcription GO:0046782 3 0.049
purine ribonucleotide catabolic process GO:0009154 208 0.048
Worm
nucleoside triphosphate metabolic process GO:0009141 230 0.048
Worm
dna repair GO:0006281 107 0.047
organophosphate catabolic process GO:0046434 232 0.047
Worm
negative regulation of nervous system development GO:0051961 156 0.046
Mouse
stem cell maintenance GO:0019827 130 0.046
Mouse
regulation of cellular catabolic process GO:0031329 242 0.046
negative regulation of immune system process GO:0002683 209 0.046
Mouse
positive regulation of nervous system development GO:0051962 221 0.046
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.045
Worm
leukocyte differentiation GO:0002521 342 0.045
cellular amino acid metabolic process GO:0006520 103 0.044
cellular response to dna damage stimulus GO:0006974 207 0.044
Worm
atp metabolic process GO:0046034 75 0.044
Worm
positive regulation of viral process GO:0048524 5 0.044
nucleoside monophosphate metabolic process GO:0009123 85 0.044
Worm
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.043
positive regulation of cytokine production GO:0001819 174 0.043
positive regulation of interferon alpha production GO:0032727 4 0.043
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.043
Worm
posttranscriptional regulation of gene expression GO:0010608 155 0.042
Mouse Worm
chromatin organization GO:0006325 206 0.042
double strand break repair GO:0006302 48 0.042
nucleotide biosynthetic process GO:0009165 78 0.041
type i interferon signaling pathway GO:0060337 10 0.041
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.041
regulation of viral genome replication GO:0045069 13 0.041
Mouse
single organism nuclear import GO:1902593 95 0.040
Human
reactive oxygen species metabolic process GO:0072593 84 0.040
production of small rna involved in gene silencing by rna GO:0070918 6 0.040
Mouse Worm
modification dependent macromolecule catabolic process GO:0043632 133 0.039
purine ribonucleoside metabolic process GO:0046128 241 0.039
Worm
nucleoside phosphate biosynthetic process GO:1901293 79 0.038
cellular amine metabolic process GO:0044106 44 0.038
negative regulation of lymphocyte activation GO:0051250 91 0.038
regulation of interleukin 6 production GO:0032675 55 0.038
endocytosis GO:0006897 168 0.038
cellular ketone metabolic process GO:0042180 84 0.036
organophosphate biosynthetic process GO:0090407 122 0.036
cellular response to molecule of bacterial origin GO:0071219 83 0.036
nucleotide metabolic process GO:0009117 332 0.036
Worm
regulation of organelle organization GO:0033043 289 0.036
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.036
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.036
Worm
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.035
response to lipopolysaccharide GO:0032496 128 0.035
purine ribonucleotide metabolic process GO:0009150 290 0.035
Worm
purine nucleoside metabolic process GO:0042278 241 0.035
Worm
microtubule based process GO:0007017 236 0.035
Mouse
purine nucleotide catabolic process GO:0006195 211 0.035
Worm
cellular protein catabolic process GO:0044257 155 0.034
viral transcription GO:0019083 3 0.034
positive regulation of immune effector process GO:0002699 107 0.034
Mouse
regulation of toll like receptor signaling pathway GO:0034121 20 0.034
purine nucleoside triphosphate catabolic process GO:0009146 203 0.034
Worm
cytoplasmic transport GO:0016482 234 0.033
Human
skin development GO:0043588 220 0.033
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.033
stem cell differentiation GO:0048863 268 0.033
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.033
regulation of lymphocyte activation GO:0051249 240 0.033
mitotic cell cycle GO:0000278 195 0.033
negative regulation of cell activation GO:0050866 111 0.033
intracellular protein transport GO:0006886 204 0.033
Human
membrane organization GO:0061024 245 0.033
ubiquitin dependent protein catabolic process GO:0006511 129 0.032
purine ribonucleoside catabolic process GO:0046130 205 0.032
Worm
immune response activating signal transduction GO:0002757 116 0.032
Human Mouse
leukocyte proliferation GO:0070661 172 0.032
organonitrogen compound biosynthetic process GO:1901566 192 0.032
positive regulation of defense response GO:0031349 124 0.031
Human Mouse
positive regulation of cell death GO:0010942 224 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.031
purine nucleoside monophosphate metabolic process GO:0009126 81 0.031
Worm
regulation of leukocyte differentiation GO:1902105 159 0.030
interleukin 6 production GO:0032635 58 0.030
nucleocytoplasmic transport GO:0006913 139 0.030
Human
response to interferon alpha GO:0035455 7 0.030
mitotic cell cycle process GO:1903047 159 0.030
leukocyte mediated immunity GO:0002443 174 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
amine metabolic process GO:0009308 45 0.029
regulation of cd8 positive alpha beta t cell activation GO:2001185 3 0.029
positive regulation of hydrolase activity GO:0051345 148 0.029
mapk cascade GO:0000165 281 0.029
actin cytoskeleton organization GO:0030036 220 0.029
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.029
Mouse
interaction with host GO:0051701 22 0.028
regulation of cell migration GO:0030334 219 0.028
Human
cytokine mediated signaling pathway GO:0019221 115 0.028
negative regulation of cell development GO:0010721 169 0.028
Mouse
toll like receptor signaling pathway GO:0002224 38 0.028
methylation GO:0032259 134 0.028
transmembrane transport GO:0055085 412 0.028
response to extracellular stimulus GO:0009991 127 0.028
homeostasis of number of cells GO:0048872 210 0.028
covalent chromatin modification GO:0016569 163 0.027
small gtpase mediated signal transduction GO:0007264 97 0.027
interferon beta biosynthetic process GO:0045350 4 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
erythrocyte differentiation GO:0030218 88 0.027
regulation of cell cycle GO:0051726 281 0.027
Mouse
negative regulation of molecular function GO:0044092 258 0.027
hair follicle morphogenesis GO:0031069 29 0.026
Mouse
negative regulation of leukocyte differentiation GO:1902106 51 0.026
response to interferon gamma GO:0034341 34 0.026
organism emergence from protective structure GO:0071684 4 0.026
Worm
regulation of cellular ketone metabolic process GO:0010565 66 0.026
regulation of ion transport GO:0043269 215 0.026
toll like receptor 7 signaling pathway GO:0034154 4 0.026
nucleoside catabolic process GO:0009164 206 0.026
Worm
schwann cell differentiation GO:0014037 26 0.026
Mouse
hormone metabolic process GO:0042445 86 0.025
microtubule cytoskeleton organization GO:0000226 157 0.025
Mouse
cytoplasmic pattern recognition receptor signaling pathway GO:0002753 10 0.025
Human Mouse
cation transport GO:0006812 399 0.025
type i interferon production GO:0032606 29 0.025
b cell activation GO:0042113 161 0.025
regulation of cytoskeleton organization GO:0051493 122 0.025
regulation of protein localization GO:0032880 231 0.025
Human
regulation of cytokine biosynthetic process GO:0042035 59 0.025
citrate metabolic process GO:0006101 3 0.024
lipid localization GO:0010876 126 0.024
regulation of cellular component biogenesis GO:0044087 181 0.024
cellular response to type i interferon GO:0071357 10 0.024
positive regulation of apoptotic process GO:0043065 217 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
Worm
regulation of intracellular transport GO:0032386 159 0.024
Human
multicellular organismal homeostasis GO:0048871 164 0.024
negative regulation of immune effector process GO:0002698 55 0.023
Mouse
cellular response to lipid GO:0071396 145 0.023
pre mirna processing GO:0031054 3 0.023
Mouse
protein targeting GO:0006605 143 0.023
Human
regulation of cellular component size GO:0032535 121 0.023
protein oligomerization GO:0051259 67 0.023
negative regulation of t cell activation GO:0050868 65 0.023
epidermis development GO:0008544 187 0.023
Mouse
positive regulation of myelination GO:0031643 5 0.023
Mouse
positive regulation of protein complex assembly GO:0031334 45 0.023
regulation of proteolysis GO:0030162 164 0.023
myeloid leukocyte differentiation GO:0002573 119 0.022
regulation of protein transport GO:0051223 163 0.022
Human
response to organonitrogen compound GO:0010243 246 0.022
b cell differentiation GO:0030183 78 0.022
digestive system development GO:0055123 200 0.022
Mouse
regulation of neuron differentiation GO:0045664 281 0.022
Mouse
histone modification GO:0016570 159 0.022
gtp catabolic process GO:0006184 143 0.022
forebrain development GO:0030900 302 0.022
Mouse
actin filament polymerization GO:0030041 44 0.022
protein import GO:0017038 101 0.022
Human
cellular lipid metabolic process GO:0044255 323 0.022
positive regulation of protein catabolic process GO:0045732 60 0.022
regionalization GO:0003002 337 0.022
protein localization to nucleus GO:0034504 121 0.022
Human
myeloid cell homeostasis GO:0002262 114 0.022
glial cell differentiation GO:0010001 131 0.022
Mouse
regulation of protein kinase activity GO:0045859 232 0.022
natural killer cell proliferation GO:0001787 3 0.021
positive regulation of cytokine biosynthetic process GO:0042108 40 0.021
ribonucleotide metabolic process GO:0009259 291 0.021
Worm
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
Worm
cell activation involved in immune response GO:0002263 126 0.021
ossification GO:0001503 216 0.021
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.021
synaptic transmission GO:0007268 329 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.021
mammary gland epithelium development GO:0061180 65 0.021
response to nutrient levels GO:0031667 109 0.020
gene silencing GO:0016458 38 0.020
Mouse Worm
spermatogenesis GO:0007283 284 0.020
regulation of actin filament length GO:0030832 45 0.020
regulation of cellular amine metabolic process GO:0033238 20 0.020
inflammatory response GO:0006954 244 0.020
cellular component assembly involved in morphogenesis GO:0010927 139 0.020
Mouse
respiratory tube development GO:0030323 167 0.020
Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.020
ras protein signal transduction GO:0007265 77 0.020
chromatin modification GO:0016568 187 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.020
Worm
guanosine containing compound metabolic process GO:1901068 144 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
Worm
neuronal action potential GO:0019228 54 0.020
ion transmembrane transport GO:0034220 361 0.020
mast cell proliferation GO:0070662 4 0.020
glycosyl compound catabolic process GO:1901658 206 0.020
Worm
cell type specific apoptotic process GO:0097285 268 0.020
Mouse
gonad development GO:0008406 141 0.020
response to exogenous dsrna GO:0043330 22 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
negative regulation of viral transcription GO:0032897 3 0.019
lymphocyte differentiation GO:0030098 242 0.019
organelle assembly GO:0070925 177 0.019
Mouse
muscle cell development GO:0055001 133 0.019
Mouse
angiogenesis GO:0001525 201 0.019
Mouse
hair follicle cell proliferation GO:0071335 3 0.019
Mouse
regulation of hormone levels GO:0010817 211 0.019
cellular response to organic cyclic compound GO:0071407 87 0.019
Mouse Worm
response to molecule of bacterial origin GO:0002237 143 0.019
positive regulation of cellular catabolic process GO:0031331 148 0.019
regulation of response to wounding GO:1903034 189 0.019
purine nucleoside monophosphate catabolic process GO:0009128 58 0.019
Worm
regulation of transferase activity GO:0051338 263 0.019
regulation of body fluid levels GO:0050878 162 0.018
lung development GO:0030324 164 0.018
Mouse
t cell activation GO:0042110 289 0.018
lymphocyte proliferation GO:0046651 164 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.018
positive regulation of peptidase activity GO:0010952 49 0.018
peptidyl amino acid modification GO:0018193 336 0.018
regulation of inflammatory response GO:0050727 147 0.018
negative regulation of organelle organization GO:0010639 90 0.018
anatomical structure homeostasis GO:0060249 145 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
Worm
epithelial tube morphogenesis GO:0060562 303 0.018
Mouse
cardiac muscle tissue development GO:0048738 130 0.018
Mouse
positive regulation of cell development GO:0010720 237 0.017
Mouse
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.017
modification by symbiont of host morphology or physiology GO:0044003 4 0.017
mda 5 signaling pathway GO:0039530 1 0.017
Mouse
protein processing GO:0016485 163 0.017
male gamete generation GO:0048232 285 0.017
cellular protein complex assembly GO:0043623 116 0.017
muscle cell differentiation GO:0042692 261 0.017
Mouse
regulation of anatomical structure size GO:0090066 178 0.017
intracellular receptor signaling pathway GO:0030522 74 0.017
Human Mouse
negative regulation of transferase activity GO:0051348 85 0.017
morphogenesis of a branching structure GO:0001763 203 0.017
Mouse
negative regulation of defense response to virus GO:0050687 6 0.017
Mouse
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
generation of precursor metabolites and energy GO:0006091 103 0.017
positive regulation of transferase activity GO:0051347 167 0.017
defense response to bacterium GO:0042742 119 0.017
wnt signaling pathway GO:0016055 188 0.017
limb morphogenesis GO:0035108 149 0.016
Mouse
regulation of schwann cell proliferation GO:0010624 2 0.016
Mouse
regulation of endocytosis GO:0030100 69 0.016
carbohydrate homeostasis GO:0033500 128 0.016
olfactory learning GO:0008355 2 0.016
peptidyl tyrosine modification GO:0018212 145 0.016
regulation of defense response to virus by host GO:0050691 8 0.016
Human
ribonucleoside monophosphate metabolic process GO:0009161 80 0.016
Worm
steroid metabolic process GO:0008202 119 0.016
connective tissue development GO:0061448 179 0.016
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 95 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
apoptotic signaling pathway GO:0097190 306 0.016
regulation of peptidase activity GO:0052547 96 0.016
protein maturation GO:0051604 176 0.016
translation GO:0006412 93 0.016
regulation of actin cytoskeleton organization GO:0032956 84 0.016
regulation of leukocyte mediated immunity GO:0002703 104 0.016
establishment of organelle localization GO:0051656 122 0.016
purine nucleotide biosynthetic process GO:0006164 65 0.015
organelle fission GO:0048285 170 0.015
actin polymerization or depolymerization GO:0008154 54 0.015
protein import into nucleus GO:0006606 95 0.015
Human
response to radiation GO:0009314 165 0.015
regulation of system process GO:0044057 200 0.015
Mouse
interleukin 8 production GO:0032637 4 0.015
regulation of actin polymerization or depolymerization GO:0008064 45 0.015
stress activated mapk cascade GO:0051403 80 0.015
protein autophosphorylation GO:0046777 61 0.015
regulation of b cell differentiation GO:0045577 23 0.015
cellular response to biotic stimulus GO:0071216 92 0.015
macromolecule methylation GO:0043414 120 0.015
gland development GO:0048732 330 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
regulation of mast cell proliferation GO:0070666 4 0.015
divalent metal ion transport GO:0070838 172 0.015
regulation of t cell differentiation GO:0045580 83 0.015
regulation of interleukin 8 production GO:0032677 3 0.015
compound eye development GO:0048749 1 0.015
positive regulation of cellular component biogenesis GO:0044089 94 0.015
regulation of chromosome organization GO:0033044 83 0.015
regulation of cell adhesion GO:0030155 154 0.015
regulation of cellular response to stress GO:0080135 159 0.015
regulation of cell motility GO:2000145 236 0.015
Human
rho protein signal transduction GO:0007266 32 0.015
regulation of endopeptidase activity GO:0052548 89 0.015
developmental maturation GO:0021700 193 0.015
regulation of nucleoside metabolic process GO:0009118 130 0.015
positive regulation of protein kinase activity GO:0045860 144 0.014
proteasomal protein catabolic process GO:0010498 98 0.014
cation transmembrane transport GO:0098655 266 0.014
regulation of secretion GO:0051046 274 0.014
b cell activation involved in immune response GO:0002312 50 0.014
extrinsic apoptotic signaling pathway GO:0097191 126 0.014
regulation of tumor necrosis factor production GO:0032680 49 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
zygote asymmetric cell division GO:0010070 2 0.014
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.014
Worm
regulation of actin filament based process GO:0032970 99 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
germ cell development GO:0007281 185 0.014
glycosylation GO:0070085 62 0.014
protein acylation GO:0043543 64 0.014
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.014
female sex differentiation GO:0046660 84 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
extracellular matrix organization GO:0030198 147 0.014
rhythmic process GO:0048511 174 0.014
natural killer cell mediated cytotoxicity GO:0042267 29 0.014
actin filament organization GO:0007015 113 0.014
heart morphogenesis GO:0003007 178 0.013
Mouse
stem cell development GO:0048864 219 0.013
Mouse
oocyte construction GO:0007308 2 0.013
regulation of transmembrane transport GO:0034762 128 0.013
schwann cell proliferation GO:0014010 2 0.013
Mouse
extracellular structure organization GO:0043062 148 0.013
muscle tissue development GO:0060537 308 0.013
Mouse
progesterone metabolic process GO:0042448 4 0.013
regulation of osteoblast differentiation GO:0045667 67 0.013
regulation of mast cell differentiation GO:0060375 3 0.013
cellular amide metabolic process GO:0043603 58 0.013
organelle localization GO:0051640 179 0.013
regulation of b cell activation GO:0050864 81 0.013
regulation of cell cycle process GO:0010564 160 0.013
response to estrogen GO:0043627 24 0.013
spermatid differentiation GO:0048515 115 0.013
nitrogen compound transport GO:0071705 271 0.013
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.013
regulation of translation GO:0006417 71 0.013
jak stat cascade involved in growth hormone signaling pathway GO:0060397 4 0.013
meiotic cell cycle process GO:1903046 77 0.013
Mouse
development of primary sexual characteristics GO:0045137 143 0.013
protein secretion GO:0009306 111 0.013
negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039532 2 0.013
Mouse
synapse organization GO:0050808 125 0.013
protein localization to organelle GO:0033365 185 0.013
Human
cell fate commitment GO:0045165 210 0.013
regulation of kinase activity GO:0043549 249 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
Worm
positive regulation of cell cycle GO:0045787 92 0.012
photoreceptor cell differentiation GO:0046530 52 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
maintenance of location GO:0051235 89 0.012
blastocyst development GO:0001824 80 0.012
negative regulation of antigen receptor mediated signaling pathway GO:0050858 16 0.012
tissue remodeling GO:0048771 102 0.012
striated muscle cell development GO:0055002 125 0.012
Mouse
atp catabolic process GO:0006200 55 0.012
Worm
cation homeostasis GO:0055080 212 0.012
regulation of lymphocyte differentiation GO:0045619 107 0.012
protein polymerization GO:0051258 57 0.012
establishment or maintenance of cell polarity GO:0007163 86 0.012
cytokine biosynthetic process GO:0042089 68 0.012
hair cycle GO:0042633 90 0.012
Mouse
lymphocyte homeostasis GO:0002260 64 0.012
glucose homeostasis GO:0042593 128 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
regulation of t cell activation GO:0050863 170 0.012
purine containing compound biosynthetic process GO:0072522 70 0.012
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.012
oocyte axis specification GO:0007309 2 0.012
interferon alpha production GO:0032607 7 0.012
Human
ear development GO:0043583 200 0.012
Mouse
spermatid development GO:0007286 108 0.012
development of primary female sexual characteristics GO:0046545 73 0.012
alpha beta t cell activation GO:0046631 91 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
mrna metabolic process GO:0016071 84 0.012
cognition GO:0050890 149 0.012
lipid transport GO:0006869 98 0.011
positive regulation of protein modification process GO:0031401 299 0.011
epithelial cell proliferation GO:0050673 174 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
Mouse
nuclear transport GO:0051169 139 0.011
Human
cellular metal ion homeostasis GO:0006875 151 0.011
anion transport GO:0006820 177 0.011
feeding behavior GO:0007631 62 0.011
t cell receptor signaling pathway GO:0050852 46 0.011
protein methylation GO:0006479 81 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
protein alkylation GO:0008213 81 0.011
nuclear division GO:0000280 158 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.011

Ddx58 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.030
disease of metabolism DOID:0014667 0 0.024
cancer DOID:162 0 0.023
organ system cancer DOID:0050686 0 0.023
acquired metabolic disease DOID:0060158 0 0.011