Mus musculus

93 known processes

Whsc1l1

Wolf-Hirschhorn syndrome candidate 1-like 1 (human)

(Aliases: WHISTLE,6720429E03,AI528490,NSD3,A530023P05)

Whsc1l1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin modification GO:0016568 187 0.120
aromatic compound catabolic process GO:0019439 286 0.064
regulation of cellular amino acid metabolic process GO:0006521 5 0.062
regulation of cellular ketone metabolic process GO:0010565 66 0.062
covalent chromatin modification GO:0016569 163 0.061
protein modification by small protein conjugation or removal GO:0070647 207 0.058
cellular amino acid metabolic process GO:0006520 103 0.058
cellular nitrogen compound catabolic process GO:0044270 280 0.054
heterocycle catabolic process GO:0046700 280 0.053
chromatin organization GO:0006325 206 0.053
cytokine production GO:0001816 319 0.052
synaptic transmission GO:0007268 329 0.051
cellular ketone metabolic process GO:0042180 84 0.049
regulation of cellular amine metabolic process GO:0033238 20 0.048
cellular amine metabolic process GO:0044106 44 0.046
small gtpase mediated signal transduction GO:0007264 97 0.046
macromolecule catabolic process GO:0009057 281 0.045
amine metabolic process GO:0009308 45 0.045
peptidyl amino acid modification GO:0018193 336 0.044
positive regulation of cellular amine metabolic process GO:0033240 5 0.043
histone modification GO:0016570 159 0.042
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.041
positive regulation of protein modification process GO:0031401 299 0.040
immune effector process GO:0002252 321 0.039
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.037
ras protein signal transduction GO:0007265 77 0.036
negative regulation of molecular function GO:0044092 258 0.036
organonitrogen compound catabolic process GO:1901565 264 0.036
carbohydrate derivative catabolic process GO:1901136 231 0.036
nucleobase containing small molecule metabolic process GO:0055086 352 0.034
nucleoside triphosphate metabolic process GO:0009141 230 0.033
purine nucleoside triphosphate metabolic process GO:0009144 226 0.033
ubiquitin dependent protein catabolic process GO:0006511 129 0.032
carbohydrate metabolic process GO:0005975 230 0.032
ribonucleoside triphosphate catabolic process GO:0009203 199 0.032
nucleoside phosphate metabolic process GO:0006753 338 0.031
ribonucleotide metabolic process GO:0009259 291 0.031
rho protein signal transduction GO:0007266 32 0.031
regulation of cellular catabolic process GO:0031329 242 0.031
ribose phosphate metabolic process GO:0019693 291 0.031
lymphocyte mediated immunity GO:0002449 139 0.031
Mouse
histone methylation GO:0016571 71 0.030
protein ubiquitination GO:0016567 171 0.030
nucleoside metabolic process GO:0009116 246 0.029
regulation of cytokine production GO:0001817 266 0.029
regulation of organelle organization GO:0033043 289 0.029
nucleoside phosphate catabolic process GO:1901292 222 0.029
ribonucleoside metabolic process GO:0009119 245 0.028
positive regulation of cytokine production GO:0001819 174 0.028
protein modification by small protein conjugation GO:0032446 187 0.028
negative regulation of cellular component organization GO:0051129 194 0.028
organelle localization GO:0051640 179 0.027
establishment of vesicle localization GO:0051650 81 0.027
purine ribonucleotide metabolic process GO:0009150 290 0.027
purine nucleotide catabolic process GO:0006195 211 0.027
cellular homeostasis GO:0019725 240 0.026
cytoplasmic transport GO:0016482 234 0.026
myeloid cell differentiation GO:0030099 233 0.026
positive regulation of nervous system development GO:0051962 221 0.026
immune response regulating signaling pathway GO:0002764 125 0.026
ribonucleoside triphosphate metabolic process GO:0009199 220 0.026
cellular macromolecule catabolic process GO:0044265 206 0.026
regulation of defense response GO:0031347 233 0.026
regulation of hydrolase activity GO:0051336 246 0.026
regulation of neuron differentiation GO:0045664 281 0.026
purine nucleoside metabolic process GO:0042278 241 0.025
vesicle localization GO:0051648 86 0.025
synaptic vesicle localization GO:0097479 59 0.025
heart morphogenesis GO:0003007 178 0.024
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.024
regulation of cell motility GO:2000145 236 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
protein maturation GO:0051604 176 0.024
respiratory system development GO:0060541 190 0.023
leukocyte differentiation GO:0002521 342 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.023
organophosphate catabolic process GO:0046434 232 0.023
lipid localization GO:0010876 126 0.023
regulation of cell migration GO:0030334 219 0.023
cation transport GO:0006812 399 0.022
nucleoside catabolic process GO:0009164 206 0.022
transmembrane transport GO:0055085 412 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.022
synapse organization GO:0050808 125 0.022
establishment of synaptic vesicle localization GO:0097480 57 0.022
male gamete generation GO:0048232 285 0.022
protein methylation GO:0006479 81 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
regulation of response to wounding GO:1903034 189 0.022
positive regulation of cell development GO:0010720 237 0.022
t cell activation GO:0042110 289 0.022
negative regulation of cell development GO:0010721 169 0.022
nucleotide catabolic process GO:0009166 217 0.021
regulation of t cell activation GO:0050863 170 0.021
cell type specific apoptotic process GO:0097285 268 0.021
sensory perception GO:0007600 245 0.021
spermatogenesis GO:0007283 284 0.021
regulation of protein localization GO:0032880 231 0.021
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
response to molecule of bacterial origin GO:0002237 143 0.021
gtp catabolic process GO:0006184 143 0.021
respiratory tube development GO:0030323 167 0.020
nucleotide metabolic process GO:0009117 332 0.020
retrograde transport endosome to golgi GO:0042147 2 0.020
regulation of interleukin 6 production GO:0032675 55 0.020
hematopoietic progenitor cell differentiation GO:0002244 143 0.020
regulation of nucleotide metabolic process GO:0006140 169 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
mrna metabolic process GO:0016071 84 0.020
leukocyte mediated immunity GO:0002443 174 0.020
Mouse
nitrogen compound transport GO:0071705 271 0.020
apoptotic signaling pathway GO:0097190 306 0.020
forebrain development GO:0030900 302 0.020
homeostasis of number of cells GO:0048872 210 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
positive regulation of gtpase activity GO:0043547 85 0.020
regulation of leukocyte mediated immunity GO:0002703 104 0.020
Mouse
regulation of mapk cascade GO:0043408 248 0.020
lung development GO:0030324 164 0.020
methylation GO:0032259 134 0.020
regulation of inflammatory response GO:0050727 147 0.020
negative regulation of immune system process GO:0002683 209 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
Mouse
endocytosis GO:0006897 168 0.019
cellular response to molecule of bacterial origin GO:0071219 83 0.019
histone lysine methylation GO:0034968 50 0.019
positive regulation of cellular catabolic process GO:0031331 148 0.019
lymphocyte proliferation GO:0046651 164 0.019
adaptive immune response GO:0002250 155 0.019
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
activation of immune response GO:0002253 138 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
regulation of ossification GO:0030278 112 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
immune response activating signal transduction GO:0002757 116 0.019
regulation of purine nucleotide metabolic process GO:1900542 169 0.019
actin cytoskeleton organization GO:0030036 220 0.019
regulation of vesicle mediated transport GO:0060627 139 0.019
multicellular organism growth GO:0035264 161 0.019
reactive oxygen species metabolic process GO:0072593 84 0.019
exocytosis GO:0006887 121 0.018
regulation of cell activation GO:0050865 289 0.018
Mouse
dna repair GO:0006281 107 0.018
Mouse
sensory organ morphogenesis GO:0090596 242 0.018
regulation of nucleoside metabolic process GO:0009118 130 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
response to lipopolysaccharide GO:0032496 128 0.018
maintenance of location GO:0051235 89 0.018
intracellular protein transport GO:0006886 204 0.018
central nervous system neuron differentiation GO:0021953 162 0.018
cognition GO:0050890 149 0.018
regulation of nucleotide catabolic process GO:0030811 122 0.018
regulation of secretion GO:0051046 274 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.018
interleukin 6 production GO:0032635 58 0.018
regulation of ras protein signal transduction GO:0046578 114 0.018
purine containing compound metabolic process GO:0072521 311 0.018
synaptic vesicle transport GO:0048489 57 0.018
organelle fission GO:0048285 170 0.018
rna processing GO:0006396 105 0.018
positive regulation of organelle organization GO:0010638 128 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
digestive tract morphogenesis GO:0048546 147 0.017
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
modification dependent protein catabolic process GO:0019941 133 0.017
establishment of organelle localization GO:0051656 122 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
purine containing compound catabolic process GO:0072523 213 0.017
mapk cascade GO:0000165 281 0.017
response to acid chemical GO:0001101 111 0.017
negative regulation of lymphocyte activation GO:0051250 91 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
regulation of multi organism process GO:0043900 111 0.016
compound eye development GO:0048749 1 0.016
mitotic cell cycle GO:0000278 195 0.016
nuclear transport GO:0051169 139 0.016
regulation of protein kinase activity GO:0045859 232 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
stem cell development GO:0048864 219 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
regulation of transferase activity GO:0051338 263 0.016
camera type eye development GO:0043010 266 0.016
skeletal system development GO:0001501 356 0.015
Mouse
stem cell differentiation GO:0048863 268 0.015
oxidation reduction process GO:0055114 342 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
cellular protein complex assembly GO:0043623 116 0.015
leukocyte proliferation GO:0070661 172 0.015
protein alkylation GO:0008213 81 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
regulation of cell projection organization GO:0031344 206 0.015
macromolecule methylation GO:0043414 120 0.015
regulation of secretion by cell GO:1903530 249 0.015
regulation of lymphocyte mediated immunity GO:0002706 84 0.015
Mouse
digestive system development GO:0055123 200 0.015
Mouse
membrane organization GO:0061024 245 0.015
glycosyl compound catabolic process GO:1901658 206 0.015
skin development GO:0043588 220 0.015
cellular response to lipopolysaccharide GO:0071222 77 0.015
glucose homeostasis GO:0042593 128 0.015
learning or memory GO:0007611 148 0.015
cellular chemical homeostasis GO:0055082 215 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
protein processing GO:0016485 163 0.015
regulation of cell cycle GO:0051726 281 0.014
cellular response to lipid GO:0071396 145 0.014
cation transmembrane transport GO:0098655 266 0.014
asymmetric neuroblast division GO:0055059 1 0.014
ion transmembrane transport GO:0034220 361 0.014
negative regulation of cell activation GO:0050866 111 0.014
negative regulation of t cell activation GO:0050868 65 0.014
hindbrain development GO:0030902 128 0.014
dephosphorylation GO:0016311 129 0.014
carbohydrate homeostasis GO:0033500 128 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
regulation of kinase activity GO:0043549 249 0.014
regulation of protein maturation GO:1903317 96 0.014
stem cell proliferation GO:0072089 117 0.014
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.014
Mouse
multicellular organismal homeostasis GO:0048871 164 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.014
chemotaxis GO:0006935 247 0.014
muscle tissue development GO:0060537 308 0.014
negative regulation of nervous system development GO:0051961 156 0.014
endomembrane system organization GO:0010256 147 0.014
protein localization to organelle GO:0033365 185 0.013
anion transport GO:0006820 177 0.013
peptidyl serine modification GO:0018209 83 0.013
regulation of adaptive immune response GO:0002819 90 0.013
Mouse
appendage development GO:0048736 166 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
gland development GO:0048732 330 0.013
negative regulation of t cell proliferation GO:0042130 38 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
digestive tract development GO:0048565 190 0.013
Mouse
regulation of cytoskeleton organization GO:0051493 122 0.013
microtubule based process GO:0007017 236 0.013
t cell differentiation GO:0030217 174 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
defense response to other organism GO:0098542 197 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.013
response to organonitrogen compound GO:0010243 246 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
Mouse
guanosine containing compound metabolic process GO:1901068 144 0.013
limb development GO:0060173 166 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
placenta development GO:0001890 140 0.013
glycoprotein metabolic process GO:0009100 116 0.013
muscle system process GO:0003012 141 0.013
cellular protein catabolic process GO:0044257 155 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
response to organic cyclic compound GO:0014070 198 0.013
muscle cell differentiation GO:0042692 261 0.013
ameboidal type cell migration GO:0001667 128 0.013
cell activation involved in immune response GO:0002263 126 0.013
Mouse
regulation of neuron projection development GO:0010975 169 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
germ cell development GO:0007281 185 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
epithelial cell development GO:0002064 159 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
innate immune response GO:0045087 157 0.012
anatomical structure homeostasis GO:0060249 145 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
regulation of t cell anergy GO:0002667 4 0.012
protein targeting GO:0006605 143 0.012
regulation of proteolysis GO:0030162 164 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
regulation of cellular response to stress GO:0080135 159 0.012
Mouse
lymphocyte differentiation GO:0030098 242 0.012
regulation of carbohydrate metabolic process GO:0006109 75 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
protein catabolic process GO:0030163 221 0.012
regulation of purine nucleotide catabolic process GO:0033121 122 0.012
positive regulation of nucleoside metabolic process GO:0045979 91 0.012
regulation of binding GO:0051098 111 0.012
t cell proliferation GO:0042098 120 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
protein modification by small protein removal GO:0070646 21 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
skeletal system morphogenesis GO:0048705 203 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
peptidyl serine phosphorylation GO:0018105 74 0.011
gtp metabolic process GO:0046039 144 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
telencephalon development GO:0021537 186 0.011
stem cell maintenance GO:0019827 130 0.011
tissue homeostasis GO:0001894 115 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
nuclear division GO:0000280 158 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
regulation of t cell proliferation GO:0042129 92 0.011
regulation of protein processing GO:0070613 96 0.011
interferon gamma production GO:0032609 67 0.011
regulation of histone methylation GO:0031060 30 0.011
regulation of anatomical structure size GO:0090066 178 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
regulation of embryonic development GO:0045995 71 0.011
t cell anergy GO:0002870 4 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.011
urogenital system development GO:0001655 261 0.011
cellular lipid metabolic process GO:0044255 323 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
regulation of rho protein signal transduction GO:0035023 71 0.011
neuron death GO:0070997 154 0.011
muscle cell development GO:0055001 133 0.011
asymmetric stem cell division GO:0098722 3 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
regulation of membrane potential GO:0042391 192 0.011
extracellular structure organization GO:0043062 148 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
cardiac ventricle development GO:0003231 83 0.011
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.011
regulation of ion transport GO:0043269 215 0.011
interleukin 8 production GO:0032637 4 0.011
positive regulation of gtp catabolic process GO:0033126 85 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
alpha beta t cell activation GO:0046631 91 0.010
axonogenesis GO:0007409 274 0.010
negative regulation of protein maturation GO:1903318 79 0.010
molting cycle GO:0042303 90 0.010
blood circulation GO:0008015 195 0.010
regulation of intracellular transport GO:0032386 159 0.010
response to inorganic substance GO:0010035 96 0.010
pharynx development GO:0060465 1 0.010
regulation of hormone levels GO:0010817 211 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
regulation of chromatin modification GO:1903308 57 0.010
regulation of system process GO:0044057 200 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.010
fat cell differentiation GO:0045444 160 0.010
locomotory behavior GO:0007626 195 0.010
positive regulation of lymphocyte activation GO:0051251 140 0.010
Mouse
actin filament organization GO:0007015 113 0.010
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.010
inorganic cation transmembrane transport GO:0098662 207 0.010

Whsc1l1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.019
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.011
inherited metabolic disorder DOID:655 0 0.011
cancer DOID:162 0 0.010
Human
disease of cellular proliferation DOID:14566 0 0.010
Human