Mus musculus

0 known processes

Dcaf8

DDB1 and CUL4 associated factor 8

(Aliases: H326,AA792214,D1Dau35e,C76055,D1Ucla4,AA433120,AA408877,Wdr42a,AU018973,MGC38511)

Dcaf8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amino acid metabolic process GO:0006521 5 0.122
protein modification by small protein conjugation or removal GO:0070647 207 0.116
cellular ketone metabolic process GO:0042180 84 0.113
dna metabolic process GO:0006259 303 0.108
cellular amino acid metabolic process GO:0006520 103 0.088
cellular macromolecule catabolic process GO:0044265 206 0.080
microtubule based process GO:0007017 236 0.071
regulation of cellular ketone metabolic process GO:0010565 66 0.070
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.069
amine metabolic process GO:0009308 45 0.064
response to radiation GO:0009314 165 0.064
cellular response to dna damage stimulus GO:0006974 207 0.063
mitochondrion organization GO:0007005 134 0.063
cellular response to growth factor stimulus GO:0071363 197 0.062
generation of precursor metabolites and energy GO:0006091 103 0.062
macromolecule catabolic process GO:0009057 281 0.061
apoptotic signaling pathway GO:0097190 306 0.061
mitotic cell cycle process GO:1903047 159 0.060
protein ubiquitination GO:0016567 171 0.059
cellular carbohydrate metabolic process GO:0044262 119 0.059
protein modification by small protein conjugation GO:0032446 187 0.056
regulation of cellular amine metabolic process GO:0033238 20 0.056
carbohydrate metabolic process GO:0005975 230 0.056
ubiquitin dependent protein catabolic process GO:0006511 129 0.055
peptidyl amino acid modification GO:0018193 336 0.054
cellular amine metabolic process GO:0044106 44 0.053
regulation of mitochondrial fission GO:0090140 3 0.051
transmission of nerve impulse GO:0019226 76 0.050
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.048
modification dependent macromolecule catabolic process GO:0043632 133 0.048
negative regulation of cellular component organization GO:0051129 194 0.048
regulation of membrane potential GO:0042391 192 0.048
response to light stimulus GO:0009416 135 0.046
ribonucleotide metabolic process GO:0009259 291 0.046
mitotic cell cycle GO:0000278 195 0.045
oxidation reduction process GO:0055114 342 0.045
nucleotide metabolic process GO:0009117 332 0.044
protein catabolic process GO:0030163 221 0.044
cellular response to organonitrogen compound GO:0071417 145 0.043
intrinsic apoptotic signaling pathway GO:0097193 132 0.042
negative regulation of phosphorus metabolic process GO:0010563 184 0.041
membrane organization GO:0061024 245 0.041
nucleoside phosphate metabolic process GO:0006753 338 0.040
mapk cascade GO:0000165 281 0.039
modification dependent protein catabolic process GO:0019941 133 0.039
multicellular organism growth GO:0035264 161 0.039
glucose homeostasis GO:0042593 128 0.038
negative regulation of intracellular signal transduction GO:1902532 167 0.038
response to nutrient levels GO:0031667 109 0.037
posttranscriptional regulation of gene expression GO:0010608 155 0.036
response to endoplasmic reticulum stress GO:0034976 53 0.034
male gamete generation GO:0048232 285 0.034
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.033
regulation of organelle organization GO:0033043 289 0.033
digestive system development GO:0055123 200 0.032
positive regulation of cellular amine metabolic process GO:0033240 5 0.032
negative regulation of organelle organization GO:0010639 90 0.032
chromatin modification GO:0016568 187 0.032
organelle fission GO:0048285 170 0.032
organelle assembly GO:0070925 177 0.032
purine nucleotide metabolic process GO:0006163 302 0.031
negative regulation of cell cycle GO:0045786 123 0.031
multicellular organismal signaling GO:0035637 91 0.031
cation transport GO:0006812 399 0.031
polysaccharide metabolic process GO:0005976 39 0.030
cellular response to hormone stimulus GO:0032870 150 0.029
neuronal action potential GO:0019228 54 0.029
regulation of cellular component biogenesis GO:0044087 181 0.029
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.029
negative regulation of phosphate metabolic process GO:0045936 184 0.029
regulation of mitotic cell cycle GO:0007346 126 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.028
transmembrane transport GO:0055085 412 0.028
circadian rhythm GO:0007623 114 0.028
leukocyte differentiation GO:0002521 342 0.028
action potential GO:0001508 78 0.027
carbohydrate derivative biosynthetic process GO:1901137 183 0.027
positive regulation of protein phosphorylation GO:0001934 242 0.027
nucleobase containing small molecule metabolic process GO:0055086 352 0.027
gene silencing GO:0016458 38 0.027
organophosphate biosynthetic process GO:0090407 122 0.027
reactive oxygen species metabolic process GO:0072593 84 0.026
hexose metabolic process GO:0019318 98 0.026
digestive tract development GO:0048565 190 0.026
cytokine production GO:0001816 319 0.026
establishment of mitochondrion localization GO:0051654 4 0.025
response to peptide hormone GO:0043434 127 0.025
response to growth factor GO:0070848 198 0.025
regulation of mapk cascade GO:0043408 248 0.025
rhythmic process GO:0048511 174 0.025
cellular protein catabolic process GO:0044257 155 0.025
ribose phosphate metabolic process GO:0019693 291 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.024
intracellular protein transport GO:0006886 204 0.024
cellular response to peptide hormone stimulus GO:0071375 92 0.024
cell type specific apoptotic process GO:0097285 268 0.024
cellular response to insulin stimulus GO:0032869 78 0.024
regulation of apoptotic signaling pathway GO:2001233 197 0.024
regulation of homeostatic process GO:0032844 182 0.024
cofactor metabolic process GO:0051186 80 0.024
positive regulation of programmed cell death GO:0043068 218 0.023
response to extracellular stimulus GO:0009991 127 0.023
response to organonitrogen compound GO:0010243 246 0.023
positive regulation of organelle organization GO:0010638 128 0.023
response to peptide GO:1901652 136 0.023
dephosphorylation GO:0016311 129 0.023
protein maturation GO:0051604 176 0.023
autophagy GO:0006914 45 0.023
regulation of cell cycle process GO:0010564 160 0.023
regulation of reactive oxygen species metabolic process GO:2000377 40 0.023
carbohydrate homeostasis GO:0033500 128 0.022
response to insulin GO:0032868 100 0.022
cellular response to extracellular stimulus GO:0031668 81 0.022
regulation of cytokine production GO:0001817 266 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
regulation of engulfment of apoptotic cell GO:1901074 2 0.022
dna repair GO:0006281 107 0.022
regulation of cellular catabolic process GO:0031329 242 0.022
striated muscle tissue development GO:0014706 293 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
response to oxidative stress GO:0006979 123 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
negative regulation of phosphorylation GO:0042326 166 0.020
monosaccharide metabolic process GO:0005996 106 0.020
histone modification GO:0016570 159 0.020
regulation of chromosome organization GO:0033044 83 0.020
protein polyubiquitination GO:0000209 33 0.020
ossification GO:0001503 216 0.019
cellular lipid metabolic process GO:0044255 323 0.019
methylation GO:0032259 134 0.019
purine containing compound metabolic process GO:0072521 311 0.019
regulation of protein localization GO:0032880 231 0.019
glucan metabolic process GO:0044042 32 0.019
cation transmembrane transport GO:0098655 266 0.019
purine containing compound biosynthetic process GO:0072522 70 0.019
nucleoside phosphate biosynthetic process GO:1901293 79 0.018
microtubule cytoskeleton organization GO:0000226 157 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
nucleoside metabolic process GO:0009116 246 0.018
regulation of cell cycle GO:0051726 281 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
ribonucleotide catabolic process GO:0009261 208 0.018
digestive tract morphogenesis GO:0048546 147 0.018
chromatin organization GO:0006325 206 0.018
skeletal system development GO:0001501 356 0.018
urogenital system development GO:0001655 261 0.018
muscle tissue development GO:0060537 308 0.018
oocyte construction GO:0007308 2 0.018
ras protein signal transduction GO:0007265 77 0.018
positive regulation of protein modification process GO:0031401 299 0.018
g protein coupled receptor signaling pathway GO:0007186 243 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.018
regulation of protein transport GO:0051223 163 0.018
coenzyme metabolic process GO:0006732 52 0.018
myelination GO:0042552 74 0.018
cellular response to external stimulus GO:0071496 88 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.017
regulation of secretion GO:0051046 274 0.017
peptidyl lysine modification GO:0018205 77 0.017
cytoplasmic transport GO:0016482 234 0.017
anatomical structure homeostasis GO:0060249 145 0.017
protein acylation GO:0043543 64 0.017
regulation of cell projection organization GO:0031344 206 0.017
golgi to endosome transport GO:0006895 3 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
positive regulation of cell death GO:0010942 224 0.017
regulation of secretion by cell GO:1903530 249 0.017
spermatogenesis GO:0007283 284 0.017
learning or memory GO:0007611 148 0.017
negative regulation of cell proliferation GO:0008285 296 0.016
dna integrity checkpoint GO:0031570 28 0.016
nucleotide biosynthetic process GO:0009165 78 0.016
small molecule catabolic process GO:0044282 71 0.016
engulfment of apoptotic cell GO:0043652 3 0.016
organophosphate catabolic process GO:0046434 232 0.016
cognition GO:0050890 149 0.016
response to uv GO:0009411 44 0.016
negative regulation of nervous system development GO:0051961 156 0.015
translation GO:0006412 93 0.015
regulation of circadian rhythm GO:0042752 58 0.015
regulation of kinase activity GO:0043549 249 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
endomembrane system organization GO:0010256 147 0.015
cellular response to starvation GO:0009267 57 0.015
memory GO:0007613 58 0.015
aromatic compound catabolic process GO:0019439 286 0.015
carbohydrate biosynthetic process GO:0016051 74 0.015
wnt signaling pathway GO:0016055 188 0.015
limb morphogenesis GO:0035108 149 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.014
plasma membrane organization GO:0007009 90 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
neuron death GO:0070997 154 0.014
regulation of system process GO:0044057 200 0.014
regulation of peptidyl serine phosphorylation GO:0033135 39 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
compound eye development GO:0048749 1 0.014
carbohydrate catabolic process GO:0016052 32 0.014
regulation of myeloid cell differentiation GO:0045637 96 0.014
cerebellum development GO:0021549 77 0.014
blood circulation GO:0008015 195 0.014
regulation of intracellular transport GO:0032386 159 0.014
cellular hyperosmotic salinity response GO:0071475 0 0.014
proteasomal protein catabolic process GO:0010498 98 0.014
plus end directed organelle transport along microtubule GO:0072386 2 0.014
mitochondrion transport along microtubule GO:0047497 3 0.014
protein localization to chromatin GO:0071168 3 0.014
t cell activation GO:0042110 289 0.014
regulation of interleukin 8 production GO:0032677 3 0.014
nuclear division GO:0000280 158 0.014
divalent inorganic cation transport GO:0072511 178 0.014
axon ensheathment GO:0008366 76 0.014
heterocycle catabolic process GO:0046700 280 0.014
developmental maturation GO:0021700 193 0.014
pyruvate metabolic process GO:0006090 28 0.014
regulation of cellular response to stress GO:0080135 159 0.014
peptidyl serine phosphorylation GO:0018105 74 0.014
regulation of cell cycle phase transition GO:1901987 77 0.014
energy derivation by oxidation of organic compounds GO:0015980 77 0.014
nucleoside monophosphate metabolic process GO:0009123 85 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
ion transmembrane transport GO:0034220 361 0.014
sensory perception GO:0007600 245 0.014
regulation of transferase activity GO:0051338 263 0.014
cellular response to peptide GO:1901653 92 0.014
cellular amino acid catabolic process GO:0009063 25 0.013
negative regulation of viral transcription GO:0032897 3 0.013
peptidyl serine modification GO:0018209 83 0.013
negative regulation of mapk cascade GO:0043409 65 0.013
interleukin 8 production GO:0032637 4 0.013
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.013
ribonucleotide biosynthetic process GO:0009260 59 0.013
myeloid cell differentiation GO:0030099 233 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
locomotory behavior GO:0007626 195 0.013
positive regulation of growth GO:0045927 104 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.013
positive regulation of dna templated transcription elongation GO:0032786 2 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
negative regulation of mitotic cell cycle GO:0045930 58 0.013
insulin receptor signaling pathway GO:0008286 49 0.013
muscle cell differentiation GO:0042692 261 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
metencephalon development GO:0022037 89 0.013
nitrogen compound transport GO:0071705 271 0.013
cellular glucan metabolic process GO:0006073 32 0.013
glycerophospholipid metabolic process GO:0006650 71 0.013
regulation of synaptic plasticity GO:0048167 87 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
purine nucleotide biosynthetic process GO:0006164 65 0.012
energy reserve metabolic process GO:0006112 39 0.012
protein kinase b signaling GO:0043491 74 0.012
negative regulation of multi organism process GO:0043901 68 0.012
negative regulation of cell cycle process GO:0010948 69 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
negative regulation of protein metabolic process GO:0051248 282 0.012
regionalization GO:0003002 337 0.012
skeletal muscle organ development GO:0060538 163 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
regulation of glucose metabolic process GO:0010906 60 0.012
immune effector process GO:0002252 321 0.012
ensheathment of neurons GO:0007272 76 0.012
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.012
sister chromatid cohesion GO:0007062 12 0.012
kidney development GO:0001822 213 0.012
hexose biosynthetic process GO:0019319 39 0.012
negative regulation of protein modification process GO:0031400 163 0.012
negative regulation of cytokine production GO:0001818 84 0.012
phospholipid metabolic process GO:0006644 87 0.012
regulation of hydrolase activity GO:0051336 246 0.012
protein localization to organelle GO:0033365 185 0.012
oocyte anterior posterior axis specification GO:0007314 2 0.012
cell maturation GO:0048469 127 0.012
epithelial cell proliferation GO:0050673 174 0.012
renal system development GO:0072001 225 0.012
ear development GO:0043583 200 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
germ cell development GO:0007281 185 0.011
fat cell differentiation GO:0045444 160 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
regulation of cell cycle g1 s phase transition GO:1902806 35 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
establishment of organelle localization GO:0051656 122 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
regulation of neuron projection development GO:0010975 169 0.011
maintenance of location GO:0051235 89 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
regulation of tor signaling GO:0032006 17 0.011
covalent chromatin modification GO:0016569 163 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.011
cell cell junction organization GO:0045216 72 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
response to epidermal growth factor GO:0070849 4 0.011
signal transduction by p53 class mediator GO:0072331 51 0.011
adaptive immune response GO:0002250 155 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
substantia nigra development GO:0021762 2 0.011
response to starvation GO:0042594 65 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
lymphocyte differentiation GO:0030098 242 0.011
neuromuscular process GO:0050905 99 0.011
protein targeting GO:0006605 143 0.011
tissue homeostasis GO:0001894 115 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
alpha amino acid metabolic process GO:1901605 59 0.011
cellular response to acid chemical GO:0071229 68 0.011
regulation of cell activation GO:0050865 289 0.011
myeloid cell homeostasis GO:0002262 114 0.011
smoothened signaling pathway GO:0007224 105 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
female gamete generation GO:0007292 74 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
cell adhesion GO:0007155 329 0.011
organelle localization GO:0051640 179 0.011
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.011
cell cycle checkpoint GO:0000075 47 0.011
extracellular matrix organization GO:0030198 147 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
negative regulation of molecular function GO:0044092 258 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.010
response to inorganic substance GO:0010035 96 0.010
negative regulation of homeostatic process GO:0032845 71 0.010
establishment or maintenance of neuroblast polarity GO:0045196 1 0.010
regulation of transmembrane transport GO:0034762 128 0.010
sulfur compound metabolic process GO:0006790 100 0.010
nucleoside phosphate catabolic process GO:1901292 222 0.010
appendage development GO:0048736 166 0.010
regulation of ossification GO:0030278 112 0.010
protein localization to membrane GO:0072657 108 0.010
synaptic transmission GO:0007268 329 0.010
positive regulation of leukocyte differentiation GO:1902107 86 0.010
purine nucleotide catabolic process GO:0006195 211 0.010
divalent metal ion transport GO:0070838 172 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
protein localization to plasma membrane GO:0072659 57 0.010
regulation of generation of precursor metabolites and energy GO:0043467 38 0.010
negative regulation of wnt signaling pathway GO:0030178 73 0.010
regulation of cell size GO:0008361 72 0.010
mitotic nuclear division GO:0007067 48 0.010
regulation of mitochondrion organization GO:0010821 27 0.010
multi multicellular organism process GO:0044706 109 0.010

Dcaf8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.019
disease of anatomical entity DOID:7 0 0.014
cardiovascular system disease DOID:1287 0 0.014
disease of cellular proliferation DOID:14566 0 0.011