Mus musculus

0 known processes

Tpte

transmembrane phosphatase with tensin homology

(Aliases: Pten2,MGC130293)

Tpte biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
camera type eye development GO:0043010 266 0.201
cellular amino acid metabolic process GO:0006520 103 0.172
renal system development GO:0072001 225 0.148
ion transmembrane transport GO:0034220 361 0.136
urogenital system development GO:0001655 261 0.125
skin development GO:0043588 220 0.124
amino acid betaine transport GO:0015838 3 0.121
regulation of cellular amino acid metabolic process GO:0006521 5 0.120
cellular ketone metabolic process GO:0042180 84 0.112
amine metabolic process GO:0009308 45 0.107
response to acid chemical GO:0001101 111 0.100
positive regulation of cellular amine metabolic process GO:0033240 5 0.097
peptidyl tyrosine modification GO:0018212 145 0.095
cation transport GO:0006812 399 0.092
hindbrain development GO:0030902 128 0.087
neural tube development GO:0021915 160 0.084
regulation of cellular ketone metabolic process GO:0010565 66 0.083
sensory perception GO:0007600 245 0.073
organic hydroxy compound metabolic process GO:1901615 203 0.069
anion transmembrane transport GO:0098656 71 0.068
cation transmembrane transport GO:0098655 266 0.066
peptidyl amino acid modification GO:0018193 336 0.065
circulatory system process GO:0003013 197 0.065
regulation of cellular amine metabolic process GO:0033238 20 0.063
transmembrane transport GO:0055085 412 0.063
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.062
cellular amine metabolic process GO:0044106 44 0.054
small molecule biosynthetic process GO:0044283 132 0.054
monocarboxylic acid metabolic process GO:0032787 191 0.050
hematopoietic progenitor cell differentiation GO:0002244 143 0.049
inorganic ion transmembrane transport GO:0098660 234 0.049
regulation of cell cycle GO:0051726 281 0.047
regulation of cell migration GO:0030334 219 0.047
gland development GO:0048732 330 0.047
regulation of apoptotic signaling pathway GO:2001233 197 0.044
response to radiation GO:0009314 165 0.043
morphogenesis of embryonic epithelium GO:0016331 159 0.043
carnitine transport GO:0015879 3 0.042
regionalization GO:0003002 337 0.042
regulation of cell activation GO:0050865 289 0.042
methionine transport GO:0015821 1 0.040
regulation of kinase activity GO:0043549 249 0.040
epithelial cell development GO:0002064 159 0.039
regulation of ion transport GO:0043269 215 0.038
macromolecule catabolic process GO:0009057 281 0.036
paramesonephric duct development GO:0061205 3 0.036
epithelial tube morphogenesis GO:0060562 303 0.036
organonitrogen compound catabolic process GO:1901565 264 0.036
muscle tissue development GO:0060537 308 0.036
development of primary sexual characteristics GO:0045137 143 0.035
cell adhesion GO:0007155 329 0.035
cell maturation GO:0048469 127 0.034
anion transport GO:0006820 177 0.034
regulation of calcium ion transport GO:0051924 69 0.034
skeletal system development GO:0001501 356 0.033
cellular modified amino acid metabolic process GO:0006575 63 0.032
tube formation GO:0035148 140 0.032
epithelial tube formation GO:0072175 130 0.032
multicellular organism growth GO:0035264 161 0.032
positive regulation of apoptotic process GO:0043065 217 0.032
cochlea development GO:0090102 35 0.031
skeletal system morphogenesis GO:0048705 203 0.031
inner ear receptor cell development GO:0060119 39 0.031
embryonic epithelial tube formation GO:0001838 130 0.031
lipid transport GO:0006869 98 0.030
ribose phosphate metabolic process GO:0019693 291 0.030
positive regulation of protein phosphorylation GO:0001934 242 0.029
purine nucleotide metabolic process GO:0006163 302 0.029
divalent inorganic cation transport GO:0072511 178 0.029
response to organic cyclic compound GO:0014070 198 0.029
regulation of mitotic cell cycle GO:0007346 126 0.028
somatotropin secreting cell differentiation GO:0060126 4 0.028
organic cyclic compound catabolic process GO:1901361 295 0.028
regulation of transferase activity GO:0051338 263 0.028
digestive system development GO:0055123 200 0.027
dna metabolic process GO:0006259 303 0.027
membrane organization GO:0061024 245 0.027
cellular macromolecule catabolic process GO:0044265 206 0.027
positive regulation of protein modification process GO:0031401 299 0.027
purine ribonucleotide metabolic process GO:0009150 290 0.026
regulation of nucleotide metabolic process GO:0006140 169 0.026
nucleoside triphosphate metabolic process GO:0009141 230 0.026
sensory organ morphogenesis GO:0090596 242 0.026
connective tissue development GO:0061448 179 0.026
g protein coupled receptor signaling pathway GO:0007186 243 0.026
negative regulation of cellular component organization GO:0051129 194 0.026
nucleotide metabolic process GO:0009117 332 0.025
regulation of metal ion transport GO:0010959 106 0.025
carboxylic acid transport GO:0046942 100 0.025
development of primary female sexual characteristics GO:0046545 73 0.025
kidney epithelium development GO:0072073 121 0.025
transmission of nerve impulse GO:0019226 76 0.025
muscle cell proliferation GO:0033002 52 0.024
axis elongation involved in somitogenesis GO:0090245 4 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
stem cell development GO:0048864 219 0.024
inflammatory response GO:0006954 244 0.024
lipid localization GO:0010876 126 0.024
positive regulation of cellular catabolic process GO:0031331 148 0.024
locomotory behavior GO:0007626 195 0.023
exocytosis GO:0006887 121 0.023
regulation of microtubule based process GO:0032886 52 0.023
organic acid transport GO:0015849 101 0.023
microtubule cytoskeleton organization GO:0000226 157 0.023
microtubule based process GO:0007017 236 0.023
tube closure GO:0060606 91 0.023
positive regulation of cell death GO:0010942 224 0.023
muscle cell development GO:0055001 133 0.023
primary neural tube formation GO:0014020 95 0.023
divalent metal ion transport GO:0070838 172 0.023
engulfment of apoptotic cell GO:0043652 3 0.023
lymphocyte differentiation GO:0030098 242 0.022
gonad development GO:0008406 141 0.022
cation homeostasis GO:0055080 212 0.022
regulation of interleukin 8 production GO:0032677 3 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.022
regulation of membrane potential GO:0042391 192 0.022
positive regulation of hydrolase activity GO:0051345 148 0.022
mesonephric epithelium development GO:0072163 94 0.022
regulation of purine nucleotide catabolic process GO:0033121 122 0.022
sperm motility GO:0030317 47 0.022
positive regulation of secretion GO:0051047 130 0.021
steroid metabolic process GO:0008202 119 0.021
regulation of t cell activation GO:0050863 170 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.021
regulation of protein kinase activity GO:0045859 232 0.021
regulation of nucleoside metabolic process GO:0009118 130 0.020
glycerolipid metabolic process GO:0046486 122 0.020
ureteric bud development GO:0001657 94 0.020
muscle fiber development GO:0048747 76 0.020
mesonephric tubule development GO:0072164 94 0.020
cellular lipid metabolic process GO:0044255 323 0.020
negative regulation of growth GO:0045926 99 0.020
regulation of protein transport GO:0051223 163 0.019
sensory perception of mechanical stimulus GO:0050954 107 0.019
regulation of transmembrane transport GO:0034762 128 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.019
regulation of ossification GO:0030278 112 0.019
appendage development GO:0048736 166 0.019
regulation of muscle tissue development GO:1901861 97 0.019
striated muscle tissue development GO:0014706 293 0.019
placenta development GO:0001890 140 0.019
amino acid transmembrane transport GO:0003333 37 0.019
oviduct development GO:0060066 3 0.019
somite development GO:0061053 81 0.019
regulation of secretion GO:0051046 274 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
fertilization GO:0009566 127 0.018
neuron apoptotic process GO:0051402 142 0.018
regulation of hormone levels GO:0010817 211 0.018
negative regulation of molecular function GO:0044092 258 0.018
action potential GO:0001508 78 0.018
carboxylic acid biosynthetic process GO:0046394 86 0.018
positive regulation of protein kinase activity GO:0045860 144 0.018
organelle fission GO:0048285 170 0.017
striated muscle cell development GO:0055002 125 0.017
nephron development GO:0072006 109 0.017
chondrocyte differentiation GO:0002062 72 0.017
cell division GO:0051301 120 0.017
carnitine transmembrane transport GO:1902603 3 0.017
developmental maturation GO:0021700 193 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
oxidation reduction process GO:0055114 342 0.017
morphogenesis of a branching structure GO:0001763 203 0.017
negative regulation of hormone metabolic process GO:0032351 4 0.017
modification dependent macromolecule catabolic process GO:0043632 133 0.017
blood circulation GO:0008015 195 0.017
synaptic transmission GO:0007268 329 0.017
leukocyte proliferation GO:0070661 172 0.017
hydrogen ion transmembrane transport GO:1902600 25 0.017
stem cell differentiation GO:0048863 268 0.016
female gonad development GO:0008585 71 0.016
regulation of asymmetric cell division GO:0009786 4 0.016
kidney development GO:0001822 213 0.016
renal tubule development GO:0061326 87 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.016
cellular protein catabolic process GO:0044257 155 0.016
positive regulation of nervous system development GO:0051962 221 0.016
paraxial mesodermal cell fate commitment GO:0048343 2 0.016
neural tube formation GO:0001841 108 0.016
t cell activation GO:0042110 289 0.016
respiratory system development GO:0060541 190 0.016
interleukin 8 production GO:0032637 4 0.016
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.016
monocarboxylic acid transport GO:0015718 44 0.016
purine containing compound metabolic process GO:0072521 311 0.016
response to light stimulus GO:0009416 135 0.016
appendage morphogenesis GO:0035107 149 0.016
mesoderm development GO:0007498 100 0.016
hormone metabolic process GO:0042445 86 0.015
protein maturation GO:0051604 176 0.015
response to organonitrogen compound GO:0010243 246 0.015
ensheathment of neurons GO:0007272 76 0.015
axon ensheathment GO:0008366 76 0.015
mechanoreceptor differentiation GO:0042490 67 0.015
amino acid transport GO:0006865 61 0.015
blood vessel morphogenesis GO:0048514 285 0.015
inorganic anion transport GO:0015698 43 0.015
detection of light stimulus GO:0009583 25 0.015
development of primary male sexual characteristics GO:0046546 88 0.015
segmentation GO:0035282 93 0.015
single organism cell adhesion GO:0098602 156 0.015
androgen biosynthetic process GO:0006702 4 0.015
neuromuscular process GO:0050905 99 0.015
branching morphogenesis of an epithelial tube GO:0048754 159 0.015
organic hydroxy compound transport GO:0015850 93 0.015
mesonephros development GO:0001823 97 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.015
regulation of organelle organization GO:0033043 289 0.015
cellular response to lipid GO:0071396 145 0.015
regulation of neurotransmitter levels GO:0001505 87 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
midgut development GO:0007494 4 0.015
lateral inhibition GO:0046331 1 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
positive regulation of organelle organization GO:0010638 128 0.015
cellular response to organic cyclic compound GO:0071407 87 0.015
single fertilization GO:0007338 82 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.015
aromatic compound catabolic process GO:0019439 286 0.015
regulation of cellular protein catabolic process GO:1903362 61 0.014
regulation of cell division GO:0051302 76 0.014
positive regulation of cell cycle GO:0045787 92 0.014
regulation of anatomical structure size GO:0090066 178 0.014
mesonephric tubule morphogenesis GO:0072171 63 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
neutral lipid metabolic process GO:0006638 57 0.014
sodium ion transport GO:0006814 73 0.014
regulation of cell adhesion GO:0030155 154 0.014
embryonic placenta development GO:0001892 98 0.014
regulation of defense response GO:0031347 233 0.014
germ cell development GO:0007281 185 0.014
olfactory lobe development GO:0021988 32 0.014
negative regulation of cell cycle GO:0045786 123 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
heterocycle catabolic process GO:0046700 280 0.014
cytokine production GO:0001816 319 0.014
sensory perception of light stimulus GO:0050953 54 0.014
innate immune response GO:0045087 157 0.014
nucleoside catabolic process GO:0009164 206 0.014
male gamete generation GO:0048232 285 0.013
endocytosis GO:0006897 168 0.013
positive regulation of proteolysis GO:0045862 85 0.013
mitotic cell cycle process GO:1903047 159 0.013
bmp signaling pathway GO:0030509 93 0.013
proteasomal protein catabolic process GO:0010498 98 0.013
defense response to bacterium GO:0042742 119 0.013
sequestering of metal ion GO:0051238 19 0.013
female gamete generation GO:0007292 74 0.013
steroid biosynthetic process GO:0006694 47 0.013
protein localization to membrane GO:0072657 108 0.013
response to inorganic substance GO:0010035 96 0.013
compound eye development GO:0048749 1 0.013
nephron epithelium development GO:0072009 92 0.013
regulation of lipid transport GO:0032368 36 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.013
inner ear receptor cell differentiation GO:0060113 61 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
regulation of secretion by cell GO:1903530 249 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
cardiac muscle tissue growth GO:0055017 37 0.013
methylation GO:0032259 134 0.013
regulation of b cell activation GO:0050864 81 0.012
neuron projection guidance GO:0097485 141 0.012
positive regulation of cell adhesion GO:0045785 80 0.012
mesenchyme development GO:0060485 152 0.012
ras protein signal transduction GO:0007265 77 0.012
sclerotome development GO:0061056 4 0.012
regulation of transforming growth factor beta2 production GO:0032909 2 0.012
negative regulation of protein processing GO:0010955 79 0.012
skeletal muscle organ development GO:0060538 163 0.012
fat soluble vitamin biosynthetic process GO:0042362 4 0.012
amino acid betaine metabolic process GO:0006577 7 0.012
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.012
establishment of blood nerve barrier GO:0008065 3 0.012
mrna metabolic process GO:0016071 84 0.012
stem cell maintenance GO:0019827 130 0.012
male sex differentiation GO:0046661 109 0.012
establishment of tissue polarity GO:0007164 28 0.012
gastrulation GO:0007369 116 0.012
forebrain neuron development GO:0021884 30 0.012
sodium ion transmembrane transport GO:0035725 49 0.012
regulation of hydrolase activity GO:0051336 246 0.012
negative regulation of response to wounding GO:1903035 77 0.012
spermatid differentiation GO:0048515 115 0.012
protein catabolic process GO:0030163 221 0.012
smoothened signaling pathway GO:0007224 105 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
ear development GO:0043583 200 0.012
positive regulation of cytoskeleton organization GO:0051495 49 0.012
mammary gland epithelium development GO:0061180 65 0.012
peptidyl serine phosphorylation GO:0018105 74 0.012
sensory perception of sound GO:0007605 97 0.012
nuclear division GO:0000280 158 0.012
regulation of protein catabolic process GO:0042176 108 0.012
interferon gamma production GO:0032609 67 0.012
regulation of lymphocyte apoptotic process GO:0070228 41 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
embryonic limb morphogenesis GO:0030326 126 0.012
sensory perception of chemical stimulus GO:0007606 51 0.012
regulation of proteolysis GO:0030162 164 0.012
cellular response to inorganic substance GO:0071241 37 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
negative regulation of lymphocyte activation GO:0051250 91 0.012
mesoderm morphogenesis GO:0048332 64 0.012
glucose transport GO:0015758 56 0.012
cardiac ventricle development GO:0003231 83 0.012
cellular homeostasis GO:0019725 240 0.012
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.012
cell cycle arrest GO:0007050 37 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
regulation of response to wounding GO:1903034 189 0.011
alcohol metabolic process GO:0006066 116 0.011
positive regulation of interleukin 8 production GO:0032757 2 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
determination of left right symmetry GO:0007368 80 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
interspecies interaction between organisms GO:0044419 83 0.011
intracellular protein transport GO:0006886 204 0.011
carnitine metabolic process GO:0009437 7 0.011
carbohydrate transport GO:0008643 62 0.011
heart morphogenesis GO:0003007 178 0.011
defense response to other organism GO:0098542 197 0.011
calcium ion transport GO:0006816 159 0.011
ameboidal type cell migration GO:0001667 128 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
regulation of homeostatic process GO:0032844 182 0.011
cytoplasmic transport GO:0016482 234 0.011
endothelium development GO:0003158 45 0.011
ribonucleoside metabolic process GO:0009119 245 0.011
limb development GO:0060173 166 0.011
regulation of inflammatory response GO:0050727 147 0.011
response to steroid hormone GO:0048545 56 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
organic hydroxy compound biosynthetic process GO:1901617 77 0.011
proton transport GO:0015992 35 0.011
response to nutrient levels GO:0031667 109 0.011
cellular alcohol metabolic process GO:0044107 3 0.011
angiogenesis GO:0001525 201 0.011
negative regulation of fibroblast growth factor production GO:0090272 2 0.011
oogenesis GO:0048477 56 0.011
regulation of nuclear division GO:0051783 56 0.011
metanephros development GO:0001656 79 0.011
regulation of cell cycle process GO:0010564 160 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.011
mitotic cell cycle GO:0000278 195 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
multicellular organismal signaling GO:0035637 91 0.010
peptidyl serine modification GO:0018209 83 0.010
organic anion transport GO:0015711 137 0.010
regulation of nucleotide catabolic process GO:0030811 122 0.010
negative regulation of protein metabolic process GO:0051248 282 0.010
cellular chemical homeostasis GO:0055082 215 0.010
positive regulation of lipid transport GO:0032370 22 0.010
response to molecule of bacterial origin GO:0002237 143 0.010
cardiac septum development GO:0003279 59 0.010
cellular response to molecule of bacterial origin GO:0071219 83 0.010
nucleoside triphosphate catabolic process GO:0009143 205 0.010
interleukin 6 production GO:0032635 58 0.010
cell fate commitment GO:0045165 210 0.010
lymphocyte proliferation GO:0046651 164 0.010
embryonic appendage morphogenesis GO:0035113 126 0.010
muscle cell differentiation GO:0042692 261 0.010
regulation of cell growth GO:0001558 91 0.010

Tpte disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
migraine DOID:6364 0 0.010
central nervous system disease DOID:331 0 0.010
brain disease DOID:936 0 0.010
disease of anatomical entity DOID:7 0 0.010
nervous system disease DOID:863 0 0.010