Mus musculus

0 known processes

LOC100038947

signal-regulatory protein beta 1-like

LOC100038947 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
detection of fungus GO:0016046 2 0.095
regulation of vesicle mediated transport GO:0060627 139 0.086
regulation of inflammatory response GO:0050727 147 0.066
t cell activation GO:0042110 289 0.063
immune effector process GO:0002252 321 0.062
regulation of lymphocyte activation GO:0051249 240 0.060
positive regulation of phagocytosis GO:0050766 26 0.057
regulation of secretion GO:0051046 274 0.056
membrane organization GO:0061024 245 0.056
negative regulation of lymphocyte activation GO:0051250 91 0.053
response to molecule of bacterial origin GO:0002237 143 0.053
regulation of cell activation GO:0050865 289 0.052
regulation of endocytosis GO:0030100 69 0.050
positive regulation of endocytosis GO:0045807 42 0.048
inflammatory response GO:0006954 244 0.047
cation transport GO:0006812 399 0.047
defense response to other organism GO:0098542 197 0.045
negative regulation of immune system process GO:0002683 209 0.041
positive regulation of cellular amine metabolic process GO:0033240 5 0.040
cytokine production GO:0001816 319 0.039
response to lipopolysaccharide GO:0032496 128 0.039
cell adhesion GO:0007155 329 0.038
regulation of protein transport GO:0051223 163 0.038
endocytosis GO:0006897 168 0.038
positive regulation of immune effector process GO:0002699 107 0.037
myeloid cell differentiation GO:0030099 233 0.036
negative regulation of immune effector process GO:0002698 55 0.036
cellular amine metabolic process GO:0044106 44 0.036
negative regulation of serotonin secretion GO:0014063 2 0.035
positive regulation of defense response GO:0031349 124 0.035
mapk cascade GO:0000165 281 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.034
regulation of protein localization GO:0032880 231 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
cellular homeostasis GO:0019725 240 0.033
regulation of cellular amino acid metabolic process GO:0006521 5 0.032
regulation of hydrolase activity GO:0051336 246 0.031
regulation of secretion by cell GO:1903530 249 0.031
cellular amino acid metabolic process GO:0006520 103 0.031
innate immune response GO:0045087 157 0.030
sequestering of calcium ion GO:0051208 18 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.030
regulation of innate immune response GO:0045088 91 0.030
nitrogen compound transport GO:0071705 271 0.029
leukocyte differentiation GO:0002521 342 0.029
maintenance of location GO:0051235 89 0.027
positive regulation of intracellular transport GO:0032388 70 0.027
cellular nitrogen compound catabolic process GO:0044270 280 0.027
cellular response to organonitrogen compound GO:0071417 145 0.026
regulation of intracellular transport GO:0032386 159 0.025
amine metabolic process GO:0009308 45 0.025
regulation of t cell activation GO:0050863 170 0.025
cellular ketone metabolic process GO:0042180 84 0.025
metal ion homeostasis GO:0055065 189 0.025
positive regulation of programmed cell death GO:0043068 218 0.025
exocytosis GO:0006887 121 0.025
regulation of defense response GO:0031347 233 0.024
organic cyclic compound catabolic process GO:1901361 295 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
antimicrobial peptide production GO:0002775 2 0.024
rho protein signal transduction GO:0007266 32 0.024
cellular chemical homeostasis GO:0055082 215 0.024
chemotaxis GO:0006935 247 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
purine ribonucleoside catabolic process GO:0046130 205 0.024
leukocyte proliferation GO:0070661 172 0.024
positive regulation of cell death GO:0010942 224 0.024
purine containing compound metabolic process GO:0072521 311 0.023
regulation of establishment of protein localization GO:0070201 181 0.023
regulation of cytokine production GO:0001817 266 0.023
negative regulation of cell activation GO:0050866 111 0.023
regulation of mast cell activation GO:0033003 21 0.023
ion transmembrane transport GO:0034220 361 0.023
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.023
nucleoside metabolic process GO:0009116 246 0.023
response to organonitrogen compound GO:0010243 246 0.022
negative regulation of cell proliferation GO:0008285 296 0.022
peptide transport GO:0015833 133 0.022
cellular response to peptidoglycan GO:0071224 4 0.022
sensory perception GO:0007600 245 0.022
cytosolic calcium ion transport GO:0060401 48 0.022
purine containing compound catabolic process GO:0072523 213 0.022
leukocyte mediated immunity GO:0002443 174 0.022
regulation of cellular amine metabolic process GO:0033238 20 0.022
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.022
transmembrane transport GO:0055085 412 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
regulation of organelle organization GO:0033043 289 0.021
macromolecule catabolic process GO:0009057 281 0.021
positive regulation of secretion GO:0051047 130 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
positive regulation of cytokine production GO:0001819 174 0.021
ribonucleoside metabolic process GO:0009119 245 0.020
detection of biotic stimulus GO:0009595 10 0.020
positive regulation of protein transport GO:0051222 93 0.020
myeloid leukocyte differentiation GO:0002573 119 0.020
nucleotide catabolic process GO:0009166 217 0.020
negative regulation of mast cell degranulation GO:0043305 4 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
antimicrobial peptide biosynthetic process GO:0002777 2 0.020
amide transport GO:0042886 138 0.020
phagocytosis GO:0006909 66 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
positive regulation of secretion by cell GO:1903532 114 0.019
detection of stimulus GO:0051606 84 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
cell type specific apoptotic process GO:0097285 268 0.019
reactive nitrogen species metabolic process GO:2001057 0 0.019
organophosphate catabolic process GO:0046434 232 0.019
cellular calcium ion homeostasis GO:0006874 119 0.019
regulation of mapk cascade GO:0043408 248 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
purine nucleoside triphosphate catabolic process GO:0009146 203 0.019
response to acid chemical GO:0001101 111 0.019
spermatogenesis GO:0007283 284 0.019
detection of yeast GO:0001879 2 0.019
tumor necrosis factor production GO:0032640 50 0.019
negative regulation of leukocyte proliferation GO:0070664 46 0.019
cation transmembrane transport GO:0098655 266 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
regulation of cytokine secretion GO:0050707 61 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
nucleotide metabolic process GO:0009117 332 0.018
aromatic compound catabolic process GO:0019439 286 0.018
sequestering of metal ion GO:0051238 19 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
lymphocyte mediated immunity GO:0002449 139 0.018
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
cellular ion homeostasis GO:0006873 165 0.018
regulation of phagocytosis GO:0050764 33 0.018
positive regulation of protein secretion GO:0050714 52 0.017
regulation of homeostatic process GO:0032844 182 0.017
cellular metal ion homeostasis GO:0006875 151 0.017
cytoplasmic transport GO:0016482 234 0.017
cell activation involved in immune response GO:0002263 126 0.017
cellular response to lipopolysaccharide GO:0071222 77 0.017
cellular response to cytokine stimulus GO:0071345 189 0.017
heterocycle catabolic process GO:0046700 280 0.017
detection of molecule of bacterial origin GO:0032490 2 0.017
i kappab kinase nf kappab signaling GO:0007249 85 0.017
myeloid leukocyte activation GO:0002274 83 0.017
regulation of serotonin secretion GO:0014062 3 0.017
protein maturation GO:0051604 176 0.017
regulation of cytoplasmic transport GO:1903649 112 0.017
response to molecule of fungal origin GO:0002238 4 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
divalent inorganic cation transport GO:0072511 178 0.016
wound healing GO:0042060 157 0.016
regulation of leukocyte mediated immunity GO:0002703 104 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
regulation of hormone levels GO:0010817 211 0.016
cytokine secretion GO:0050663 72 0.016
regulation of ion transport GO:0043269 215 0.016
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.016
regulation of protein secretion GO:0050708 82 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
tissue homeostasis GO:0001894 115 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
response to organic cyclic compound GO:0014070 198 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
organonitrogen compound catabolic process GO:1901565 264 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.015
organelle localization GO:0051640 179 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
regulation of membrane potential GO:0042391 192 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
cellular lipid metabolic process GO:0044255 323 0.015
divalent metal ion transport GO:0070838 172 0.015
leukocyte activation involved in immune response GO:0002366 126 0.015
regulated secretory pathway GO:0045055 32 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
negative regulation of molecular function GO:0044092 258 0.014
nucleoside catabolic process GO:0009164 206 0.014
cellular response to acid chemical GO:0071229 68 0.014
antibacterial peptide biosynthetic process GO:0002780 2 0.014
alpha beta t cell activation GO:0046631 91 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
regulation of cellular response to stress GO:0080135 159 0.014
oxidation reduction process GO:0055114 342 0.014
actin cytoskeleton organization GO:0030036 220 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
adaptive immune response GO:0002250 155 0.014
purine nucleotide metabolic process GO:0006163 302 0.014
positive regulation of protein modification process GO:0031401 299 0.014
skeletal system development GO:0001501 356 0.014
homeostasis of number of cells GO:0048872 210 0.014
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.014
positive regulation of cytokine secretion GO:0050715 41 0.014
immunoglobulin transcytosis in epithelial cells GO:0002414 2 0.014
male gamete generation GO:0048232 285 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
apoptotic signaling pathway GO:0097190 306 0.014
myeloid leukocyte mediated immunity GO:0002444 42 0.013
regulation of cell projection organization GO:0031344 206 0.013
regulation of cell migration GO:0030334 219 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
positive regulation of leukocyte mediated immunity GO:0002705 70 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
negative regulation of lymphocyte proliferation GO:0050672 45 0.013
cellular response to lipid GO:0071396 145 0.013
innate immune response activating signal transduction GO:0002758 50 0.013
b cell activation GO:0042113 161 0.013
muscle cell differentiation GO:0042692 261 0.013
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.013
calcium ion transport GO:0006816 159 0.013
carbohydrate metabolic process GO:0005975 230 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
detection of external biotic stimulus GO:0098581 9 0.013
regulation of ion homeostasis GO:2000021 64 0.013
blood circulation GO:0008015 195 0.013
peptidyl amino acid modification GO:0018193 336 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
hormone secretion GO:0046879 128 0.013
regulation of response to wounding GO:1903034 189 0.013
dna metabolic process GO:0006259 303 0.013
response to oxygen levels GO:0070482 62 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.012
immune response regulating signaling pathway GO:0002764 125 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
regulation of tumor necrosis factor production GO:0032680 49 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
ras protein signal transduction GO:0007265 77 0.012
action potential GO:0001508 78 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
protein secretion GO:0009306 111 0.012
protein processing GO:0016485 163 0.012
humoral immune response GO:0006959 57 0.012
lymphocyte proliferation GO:0046651 164 0.012
response to inorganic substance GO:0010035 96 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
positive regulation of inflammatory response GO:0050729 47 0.012
developmental maturation GO:0021700 193 0.012
protein catabolic process GO:0030163 221 0.012
myeloid cell activation involved in immune response GO:0002275 34 0.012
endomembrane system organization GO:0010256 147 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
calcium ion homeostasis GO:0055074 127 0.012
immune response activating signal transduction GO:0002757 116 0.012
detection of peptidoglycan GO:0032499 1 0.011
intracellular protein transport GO:0006886 204 0.011
regulation of cell motility GO:2000145 236 0.011
organic hydroxy compound transport GO:0015850 93 0.011
positive regulation of monocyte chemotaxis GO:0090026 2 0.011
lateral inhibition GO:0046331 1 0.011
cell recognition GO:0008037 83 0.011
protein ubiquitination GO:0016567 171 0.011
spermatid development GO:0007286 108 0.011
mitotic cell cycle GO:0000278 195 0.011
fat cell differentiation GO:0045444 160 0.011
ribonucleotide metabolic process GO:0009259 291 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
germ cell development GO:0007281 185 0.011
phosphatidylinositol mediated signaling GO:0048015 41 0.011
glycoprotein metabolic process GO:0009100 116 0.011
regulation of neuron differentiation GO:0045664 281 0.011
transmission of nerve impulse GO:0019226 76 0.011
cellular macromolecule catabolic process GO:0044265 206 0.011
leukocyte degranulation GO:0043299 27 0.011
receptor mediated endocytosis GO:0006898 51 0.011
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
serotonin secretion by mast cell GO:0002552 1 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
response to radiation GO:0009314 165 0.011
cation homeostasis GO:0055080 212 0.011
protein localization to organelle GO:0033365 185 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
interleukin 8 production GO:0032637 4 0.011
extracellular structure organization GO:0043062 148 0.011
regulation of cell cycle GO:0051726 281 0.011
serotonin secretion involved in inflammatory response GO:0002442 4 0.011
mitotic cell cycle process GO:1903047 159 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
renal system development GO:0072001 225 0.011
bone development GO:0060348 120 0.010
camera type eye development GO:0043010 266 0.010
epithelial tube morphogenesis GO:0060562 303 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
microtubule based process GO:0007017 236 0.010
negative regulation of proteolysis GO:0045861 74 0.010
negative regulation of leukocyte mediated immunity GO:0002704 29 0.010
peptide secretion GO:0002790 114 0.010
t cell proliferation GO:0042098 120 0.010
response to extracellular stimulus GO:0009991 127 0.010
regulation of b cell mediated immunity GO:0002712 37 0.010
negative regulation of protein processing GO:0010955 79 0.010
regulation of production of molecular mediator of immune response GO:0002700 65 0.010
regulation of natural killer cell activation GO:0032814 22 0.010
mitotic cytokinesis GO:0000281 4 0.010
positive regulation of transferase activity GO:0051347 167 0.010
monocarboxylic acid metabolic process GO:0032787 191 0.010
regulation of adaptive immune response GO:0002819 90 0.010
leukocyte migration GO:0050900 124 0.010
regulation of map kinase activity GO:0043405 120 0.010
positive regulation of innate immune response GO:0045089 80 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
defense response to bacterium GO:0042742 119 0.010
lysosome localization GO:0032418 20 0.010

LOC100038947 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.016
disease of anatomical entity DOID:7 0 0.016
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
nervous system disease DOID:863 0 0.011
disease of metabolism DOID:0014667 0 0.011