|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.985
|
Yeast |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.971
|
Yeast |
|
|
male gamete generation
|
GO:0048232 |
285 |
0.954
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.940
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.933
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.918
|
Yeast |
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.890
|
Yeast |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.887
|
Yeast |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.886
|
Yeast |
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.864
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.861
|
Yeast |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.856
|
Yeast |
|
|
germ cell development
|
GO:0007281 |
185 |
0.846
|
Fly |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.824
|
Yeast Fly |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.790
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.772
|
Yeast |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.768
|
|
|
|
regulation of glycogen catabolic process
|
GO:0005981 |
2 |
0.763
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.746
|
Yeast |
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.738
|
Yeast |
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.694
|
Yeast Worm Fly |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
45 |
0.677
|
Yeast |
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.676
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.659
|
Yeast |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.657
|
Yeast |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.650
|
Yeast |
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.615
|
Yeast |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.614
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.614
|
Yeast Worm Fly |
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.613
|
Yeast |
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.607
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.604
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.598
|
Yeast |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.586
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.567
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.565
|
Yeast |
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.565
|
|
|
|
mrna metabolic process
|
GO:0016071 |
84 |
0.564
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.555
|
Yeast Worm |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.544
|
|
|
|
glucan catabolic process
|
GO:0009251 |
5 |
0.539
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.510
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.505
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.503
|
Fly |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.498
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.494
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.486
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.480
|
Yeast Worm Fly |
|
|
positive regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902110 |
11 |
0.465
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.461
|
Yeast |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.457
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.455
|
Fly |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.453
|
Yeast |
|
|
vesicle organization
|
GO:0016050 |
60 |
0.443
|
|
|
|
cellular polysaccharide catabolic process
|
GO:0044247 |
5 |
0.435
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.428
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.428
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.427
|
Yeast |
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.427
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.426
|
|
|
|
dna repair
|
GO:0006281 |
107 |
0.418
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
48 |
0.416
|
Yeast |
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.410
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.410
|
Yeast |
|
|
spermatid development
|
GO:0007286 |
108 |
0.407
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.399
|
Yeast |
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
35 |
0.395
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.384
|
Yeast |
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
34 |
0.382
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.378
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.377
|
Yeast |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.376
|
Yeast |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.358
|
|
|
|
translesion synthesis
|
GO:0019985 |
1 |
0.354
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.340
|
Yeast Worm |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.339
|
|
|
|
dna catabolic process
|
GO:0006308 |
19 |
0.330
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.329
|
Yeast |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.329
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.325
|
Yeast |
|
|
cell cycle arrest
|
GO:0007050 |
37 |
0.321
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.318
|
Yeast |
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.310
|
Yeast |
|
|
rhythmic process
|
GO:0048511 |
174 |
0.309
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.303
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.294
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.292
|
|
|
|
mrna processing
|
GO:0006397 |
63 |
0.288
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.287
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.285
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.283
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.283
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.281
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.277
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.275
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.273
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.271
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.269
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
35 |
0.268
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.266
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
21 |
0.265
|
Yeast |
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.264
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.264
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.254
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.248
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.248
|
Yeast |
|
|
protein polyubiquitination
|
GO:0000209 |
33 |
0.248
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.247
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.246
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.240
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.235
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.229
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.228
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.228
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.228
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.223
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.222
|
|
|
|
response to iron ion
|
GO:0010039 |
4 |
0.222
|
|
|
|
er nucleus signaling pathway
|
GO:0006984 |
27 |
0.221
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.219
|
|
|
|
scf dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031146 |
10 |
0.219
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.219
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.218
|
Yeast |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.217
|
|
|
|
regeneration
|
GO:0031099 |
38 |
0.215
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.215
|
Fly |
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.213
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.211
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.211
|
Yeast |
|
|
regulation of dna catabolic process
|
GO:1903624 |
5 |
0.206
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.205
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.199
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
31 |
0.198
|
Yeast |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.191
|
|
|
|
protein complex disassembly
|
GO:0043241 |
40 |
0.190
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
33 |
0.188
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.185
|
|
|
|
regulation of metaphase anaphase transition of cell cycle
|
GO:1902099 |
9 |
0.183
|
Yeast |
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.181
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.178
|
Fly |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.173
|
Yeast |
|
|
viral life cycle
|
GO:0019058 |
36 |
0.172
|
|
|
|
negative regulation of cell cycle arrest
|
GO:0071157 |
1 |
0.170
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.170
|
|
|
|
mitochondrial outer membrane permeabilization involved in programmed cell death
|
GO:1902686 |
11 |
0.170
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.168
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.167
|
Yeast |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.167
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.166
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.163
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.163
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.157
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.155
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.154
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.153
|
Yeast Worm Fly |
|
|
regulation of mitochondrial membrane permeability
|
GO:0046902 |
17 |
0.153
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.153
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.153
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.152
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.149
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.148
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.147
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
49 |
0.146
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.146
|
Yeast |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.145
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.145
|
|
|
|
regulation of mitosis
|
GO:0007088 |
29 |
0.145
|
Yeast |
|
|
rna processing
|
GO:0006396 |
105 |
0.143
|
Yeast |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.141
|
|
|
|
positive regulation of cell cycle phase transition
|
GO:1901989 |
17 |
0.138
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.135
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.134
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.133
|
|
|
|
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway
|
GO:0043162 |
3 |
0.132
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.132
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.132
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.132
|
Yeast |
|
|
dna replication
|
GO:0006260 |
52 |
0.132
|
Yeast |
|
|
gonad development
|
GO:0008406 |
141 |
0.131
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
4 |
0.126
|
|
|
|
intermediate filament based process
|
GO:0045103 |
27 |
0.126
|
|
|
|
cardiac muscle cell development
|
GO:0055013 |
39 |
0.124
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.123
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.122
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.122
|
|
|
|
viral process
|
GO:0016032 |
41 |
0.121
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.119
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
44 |
0.118
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.117
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.115
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
34 |
0.114
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.114
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.113
|
|
|
|
secretory granule organization
|
GO:0033363 |
20 |
0.112
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.111
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.111
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.109
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.109
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.107
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.106
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.106
|
Yeast |
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
16 |
0.106
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.106
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
41 |
0.105
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.104
|
Yeast |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.103
|
Fly |
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.103
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.102
|
|
|
|
protein localization to chromatin
|
GO:0071168 |
3 |
0.102
|
|
|
|
mrna splicing via spliceosome
|
GO:0000398 |
43 |
0.102
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.102
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.101
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
11 |
0.100
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.100
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.100
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.100
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.098
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.098
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.097
|
Yeast Worm |
|
|
camera type eye development
|
GO:0043010 |
266 |
0.096
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.096
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.096
|
|
|
|
rna splicing via transesterification reactions with bulged adenosine as nucleophile
|
GO:0000377 |
43 |
0.095
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.094
|
Yeast |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.094
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.093
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.091
|
|
|
|
postreplication repair
|
GO:0006301 |
5 |
0.091
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.090
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.089
|
|
|
|
cytokinesis
|
GO:0000910 |
17 |
0.089
|
Worm |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.089
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.088
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.087
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
69 |
0.085
|
|
|
|
metaphase anaphase transition of mitotic cell cycle
|
GO:0007091 |
9 |
0.084
|
Yeast |
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.083
|
|
|
|
regulation of mrna processing
|
GO:0050684 |
41 |
0.081
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.080
|
Yeast Worm Fly |
|
|
dna biosynthetic process
|
GO:0071897 |
22 |
0.080
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.080
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.079
|
Yeast |
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.078
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
20 |
0.078
|
|
|
|
sphingolipid metabolic process
|
GO:0006665 |
45 |
0.078
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.076
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.075
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.074
|
Yeast |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.074
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.074
|
Fly |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.074
|
|
|
|
base excision repair
|
GO:0006284 |
9 |
0.073
|
|
|
|
positive regulation of mitotic cell cycle phase transition
|
GO:1901992 |
17 |
0.072
|
|
|
|
mitotic spindle checkpoint
|
GO:0071174 |
9 |
0.072
|
Yeast |
|
|
response to calcium ion
|
GO:0051592 |
20 |
0.072
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
23 |
0.072
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.071
|
Yeast Worm |
|
|
developmental maturation
|
GO:0021700 |
193 |
0.070
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.070
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.070
|
Yeast |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.070
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.069
|
|
|
|
protein localization to chromosome
|
GO:0034502 |
6 |
0.069
|
Yeast |
|
|
negative regulation of response to dna damage stimulus
|
GO:2001021 |
10 |
0.068
|
|
|
|
cardiac cell development
|
GO:0055006 |
41 |
0.068
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.068
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.068
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.068
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.067
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.066
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.066
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.066
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.066
|
Yeast |
|
|
neuron death
|
GO:0070997 |
154 |
0.066
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.065
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.065
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.065
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.065
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.064
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.063
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.063
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.063
|
|
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.063
|
Yeast Worm Fly |
|
|
response to uv a
|
GO:0070141 |
1 |
0.063
|
|
|
|
sister chromatid cohesion
|
GO:0007062 |
12 |
0.062
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.062
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.062
|
|
|
|
regulation of sister chromatid segregation
|
GO:0033045 |
13 |
0.062
|
Yeast |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.061
|
|
|
|
nucleus organization
|
GO:0006997 |
45 |
0.061
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
33 |
0.061
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.060
|
Yeast |
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.060
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.060
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.060
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.060
|
|
|
|
regulation of nuclear cell cycle dna replication
|
GO:0033262 |
2 |
0.059
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.059
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.059
|
|
|
|
glycogen catabolic process
|
GO:0005980 |
5 |
0.059
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.059
|
|
|
|
rna splicing
|
GO:0008380 |
54 |
0.057
|
|
|
|
positive regulation of mitochondrion organization
|
GO:0010822 |
17 |
0.057
|
|
|
|
gene silencing
|
GO:0016458 |
38 |
0.057
|
Yeast |
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.057
|
|
|
|
mitochondrial transport
|
GO:0006839 |
36 |
0.057
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.057
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.056
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.055
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.055
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.055
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.055
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.055
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.055
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.053
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
35 |
0.052
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.052
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
18 |
0.052
|
|
|
|
rna splicing via transesterification reactions
|
GO:0000375 |
43 |
0.051
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.051
|
|
|
|
regulation of double strand break repair via nonhomologous end joining
|
GO:2001032 |
2 |
0.050
|
|
|
|
spermatid nucleus differentiation
|
GO:0007289 |
19 |
0.049
|
|
|
|
protein depolymerization
|
GO:0051261 |
34 |
0.049
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.049
|
|
|
|
positive regulation of nuclear division
|
GO:0051785 |
27 |
0.048
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.048
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
31 |
0.048
|
|
|
|
response to ethanol
|
GO:0045471 |
18 |
0.048
|
|
|
|
liposaccharide metabolic process
|
GO:1903509 |
27 |
0.047
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.047
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
18 |
0.046
|
|
|
|
regulation of mrna splicing via spliceosome
|
GO:0048024 |
32 |
0.046
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.046
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
17 |
0.046
|
|
|
|
male gonad development
|
GO:0008584 |
88 |
0.045
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.045
|
|
|
|
histone methylation
|
GO:0016571 |
71 |
0.045
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001241 |
10 |
0.044
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.044
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.044
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.043
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
15 |
0.043
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.043
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.043
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
18 |
0.042
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
25 |
0.042
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.042
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.042
|
Yeast |
|
|
regulation of rna splicing
|
GO:0043484 |
37 |
0.041
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.041
|
|
|
|
translation
|
GO:0006412 |
93 |
0.041
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.041
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.041
|
|
|
|
rna 3 end processing
|
GO:0031123 |
20 |
0.041
|
|
|
|
growth involved in symbiotic interaction
|
GO:0044110 |
23 |
0.041
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.041
|
|
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.041
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.040
|
|
|
|
dna templated transcription termination
|
GO:0006353 |
4 |
0.040
|
Yeast |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.040
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
30 |
0.040
|
Yeast |
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
31 |
0.040
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.040
|
|
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
26 |
0.040
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
31 |
0.040
|
|
|
|
acrosome assembly
|
GO:0001675 |
11 |
0.039
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
20 |
0.039
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.039
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.039
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.039
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.038
|
|
|
|
mitochondrial membrane organization
|
GO:0007006 |
26 |
0.038
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.038
|
Yeast |
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
27 |
0.038
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.038
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.038
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.038
|
|
|
|
neuron maturation
|
GO:0042551 |
29 |
0.038
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.038
|
Yeast |
|
|
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031145 |
9 |
0.037
|
Yeast |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.037
|
Yeast |
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.037
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
19 |
0.037
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.036
|
|
|
|
positive regulation of mitotic sister chromatid separation
|
GO:1901970 |
2 |
0.036
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.036
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.036
|
Yeast |
|
|
double strand break repair via homologous recombination
|
GO:0000724 |
21 |
0.036
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.036
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
57 |
0.035
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.035
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.035
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.035
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.035
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.035
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.035
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.034
|
|
|
|
intermediate filament cytoskeleton organization
|
GO:0045104 |
26 |
0.034
|
|
|
|
regulation of carbohydrate catabolic process
|
GO:0043470 |
12 |
0.034
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.034
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
26 |
0.034
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.034
|
|
|
|
cardiac muscle tissue growth
|
GO:0055017 |
37 |
0.034
|
|
|
|
response to uv
|
GO:0009411 |
44 |
0.033
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.033
|
|
|
|
negative regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0071930 |
1 |
0.033
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
20 |
0.033
|
|
|
|
double strand break repair via nonhomologous end joining
|
GO:0006303 |
10 |
0.033
|
|
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
22 |
0.033
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.033
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.032
|
|
|
|
glycolipid metabolic process
|
GO:0006664 |
25 |
0.032
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.032
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
20 |
0.032
|
Yeast Fly |
|
|
positive regulation of striated muscle tissue development
|
GO:0045844 |
31 |
0.032
|
|
|
|
regulation of mrna metabolic process
|
GO:1903311 |
43 |
0.032
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.032
|
Yeast |
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.032
|
|
|
|
3 utr mediated mrna stabilization
|
GO:0070935 |
2 |
0.032
|
|
|
|
carbohydrate catabolic process
|
GO:0016052 |
32 |
0.032
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.032
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.031
|
|
|
|
positive regulation of chromosome segregation
|
GO:0051984 |
4 |
0.031
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
34 |
0.031
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.031
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.031
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.031
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.031
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.031
|
|
|
|
mitotic g2 dna damage checkpoint
|
GO:0007095 |
8 |
0.030
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.030
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.030
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.030
|
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.030
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.030
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.030
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.029
|
Fly |
|
|
positive regulation of triglyceride catabolic process
|
GO:0010898 |
3 |
0.029
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.029
|
Fly |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.029
|
|
|
|
polysaccharide catabolic process
|
GO:0000272 |
5 |
0.029
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.029
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.029
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
27 |
0.029
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.029
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.029
|
|
|
|
regulation of heart growth
|
GO:0060420 |
31 |
0.029
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.029
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.029
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.029
|
|
|
|
regulation of membrane permeability
|
GO:0090559 |
18 |
0.029
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.028
|
|
|
|
sperm individualization
|
GO:0007291 |
1 |
0.028
|
|
|
|
gene silencing by rna
|
GO:0031047 |
19 |
0.028
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
55 |
0.028
|
Yeast |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.028
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
10 |
0.028
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.028
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.028
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.028
|
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
9 |
0.028
|
Yeast |
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.028
|
|
|
|
protein alkylation
|
GO:0008213 |
81 |
0.028
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.028
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.027
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.027
|
Yeast |
|
|
b cell activation
|
GO:0042113 |
161 |
0.027
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.027
|
|
|
|
response to starvation
|
GO:0042594 |
65 |
0.027
|
|
|
|
positive regulation of rna splicing
|
GO:0033120 |
12 |
0.027
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.027
|
Yeast |
|
|
cellular response to gamma radiation
|
GO:0071480 |
4 |
0.027
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
62 |
0.027
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.027
|
|
|
|
positive regulation of histone modification
|
GO:0031058 |
28 |
0.027
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.027
|
|
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
38 |
0.027
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
60 |
0.027
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.026
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.026
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.026
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.026
|
|
|
|
regulation of mitotic metaphase anaphase transition
|
GO:0030071 |
8 |
0.026
|
Yeast |
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.026
|
|
|
|
response to estrogen
|
GO:0043627 |
24 |
0.026
|
|
|
|
male meiosis
|
GO:0007140 |
37 |
0.026
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
34 |
0.026
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.026
|
|
